Patents Assigned to Foundation
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Patent number: 5208121Abstract: A thin film battery is disclosed based on the use of ceramic membrane technology. The battery includes a pair of conductive collectors on which the materials for the anode and the cathode may be spin coated. The separator is formed of a porous metal oxide ceramic membrane impregnated with electrolyte so that electrical separation is maintained while ion mobility is also maintained. The entire battery can be made less than 10 microns thick while generating a potential in the 1 volt range.Type: GrantFiled: June 18, 1991Date of Patent: May 4, 1993Assignee: Wisconsin Alumni Research FoundationInventors: Mark S. Yahnke, Golan Shlomo, Marc A. Anderson
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Patent number: 5206083Abstract: Novel diamond thin films deposited on a metal or ceramic composite comprising a matrix having dispersed therein finely divided diamond or diamond-like particles are useful in improving the erosion resistance of materials used for long wave infrared transmitting applications such as domes and infrared windows.Type: GrantFiled: September 18, 1989Date of Patent: April 27, 1993Assignee: Cornell Research Foundation, Inc.Inventors: Rishi Raj, Albert J. Sievers
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Patent number: 5206165Abstract: Two immortalized human mammary epithelial cell sublines are provided. The sublines do not undergo terminal differentiation and senescence upon exposure to high calcium concentrations. The sublines exhibit positive reactivity with milk-fat globule membrane and cytokeratin anti-sera and are non-tumorigenic in athymic mice. The sublines are useful in evaluating the capacity of preselected agents to bring about a change in epithelial cell growth and in the production of proteins.Type: GrantFiled: July 9, 1991Date of Patent: April 27, 1993Assignee: Michigan Cancer FoundationInventors: Robert J. Pauley, Terry J. Paine, Herbert D. Soule
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Patent number: 5206347Abstract: A method of isolating cell surface receptors utilizing a short peptide sequence bound to an affinity column. Cell surface receptors which bind selectively to the short peptide and which are specific to various adhesion proteins may be isolated therewith from various cell preparations. These receptors, whose functional integrity has been maintained by the presence of the peptide ligand, are incorporated into liposomes and used to deliver specific compounds inside the liposomes to select tissues containing the specific adhesion proteins.Type: GrantFiled: July 13, 1990Date of Patent: April 27, 1993Assignee: La Jolla Cancer Research FoundationInventors: Erkki I. Ruoslahti, Michael D. Pierschbacher
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Patent number: 5206150Abstract: A formulation for use in detecting and/or determining peroxidase activity comprises a mixture in solution of tetramethylbenzidine, hydrogen peroxide, a buffering agent and bacitracin as a stabilizing agent. The formulation is used as a peroxidase substrate that is stable in solution for an extended period of time and provides enhanced color sensitivity.Type: GrantFiled: October 26, 1990Date of Patent: April 27, 1993Assignee: University of Kentucky Research FoundationInventor: Hsin-Hsiung Tai
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Patent number: 5205673Abstract: Apparatus and method for supporting and lifting building foundation slabs utilizing an above-slab, power cylinder activated, lift assembly and a below-slab support bracket. The bracket is an elongated plate which is inserted through a small access slot cut in the slab and then rotated to extend transversely of the slot. Lift rods are connected between the bracket and a cross arm of the lift assembly positioned above the slab. The cross arm and the bracket include apertured guides for slidably receiving and guiding pilings successively driven under the slab by power cylinders connected from the cross arm.Type: GrantFiled: July 18, 1991Date of Patent: April 27, 1993Assignee: Power Lift Foundation RepairInventors: William B. Bolin, William B. McCown, Jr.
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Patent number: 5204627Abstract: A magnetic resonance angiogram is produced by projecting a 3D array of motion sensitized NMR data. A mask which locates the vessels in the 3D array is produced by thresholding the NMR data, and this mask is combined with the 3D NMR data set to exclude signals produced by surrounding stationary tissues. An integration projection technique is used to produce the angiogram from the masked data set.Type: GrantFiled: March 14, 1991Date of Patent: April 20, 1993Assignee: Wisconsin Alumni Research FoundationInventors: Charles A. Mistretta, Frank R. Korosec, David M. Weber
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Patent number: 5203646Abstract: An underwater robot is employed to clean and/or inspect the inner surfaces of high flow rate water inlet pipes for various facilities, such as power plants, water treatment plants, etc. The robot crawls along a cable positioned within a pipe to be inspected or cleaned, and in one embodiment, includes a plurality of guidance fins which rely upon the flow of water through the pipe to position the robot therein as desired. Retractable legs can also be provided to fix the robot at a location within the pipe when it is employed to clean the pipe using a water jet or similar system. The robot can also include a water driven turbine for generating electricity for the various motors, servos and other actuators contained on board the robot. Also, the robot preferably includes wheel or pulley arrangements which further help the robot to negotiate sharp corners or other obstructions within the pipe to be inspected or cleaned.Type: GrantFiled: February 6, 1992Date of Patent: April 20, 1993Assignee: Cornell Research Foundation, Inc.Inventors: Samuel E. Landsberger, Raj Sundra, David B. Short, Benjamin F. Martin
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Patent number: 5202253Abstract: A Ca.sup.2+ dependent monoclonal antibody that specifically binds to a specific twelve peptide sequence (E D Q V D P R L I D G K) in the activation region of the Protein C. The antibody does not bind to Activated Protein C and can be used to inhibit activation of Protein C by thrombin-thrombomodulin. The antibody can be isolated from cell culture or ascites fluid in large quantities by affinity chromatography with mild conditions using the peptide bound to an immobilized substrate. The antibody has a number of specific uses in isolation and characterization of Protein C and as a model for the design of Ca.sup.2+ dependent antibodies for the isolation of other proteins, as a diagnostic, and as a therapeutic to prevent activation of Protein C. The Protein C can be naturally produced or produced by expression of the recombinant gene. Advantages of the antibody in purification of Protein C include the specificity for Protein C and not Activated Protein C, and the unique Ca.sup.Type: GrantFiled: July 12, 1991Date of Patent: April 13, 1993Assignee: Oklahoma Medical Research FoundationInventors: Charles T. Esmon, Naomi L. Esmon
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Patent number: 5202356Abstract: The present Application discloses pesticidally active compounds of the formula (I):Q Q.sup.1 CR.sup.2 =CR.sup.3 CR.sup.4 =CR.sup.5 C (.dbd.X) NHR.sup.1or a salt thereof, wherein Q is an monocyclic aromatic ring. or fused bicyclic ring system of which at least one ring is aromatic containing 9 or 10 atoms of which one may be nitrogen and the rest carbon each optionally substituted, or Q is a dihalovinyl group or a group R.sup.6 --C.tbd.C-- where R.sup.6 is C.sub.1-4 alkyl, tri C.sub.1-4 alkylsilyl, halogen or hydrogen; Q.sup.1 is a 1,2-cyclopropyl ring optionally substituted by one or more groups selected from C.sub.1-3 alkyl. halo, C.sub.1-3 haloalkyl, alkynyl, or cyano; R.sup.2,R.sup.3, R.sup.4 and R.sup.5 are the same or different with at least one being hydrogen and the others being independently selected from hydrogen, halo. C.sub.1-4 alkyl or C.sub.1-4 haloalkyl; X is oxygen or sulphur; and R.sup.1 is selected from hydrogen and C.sub.Type: GrantFiled: July 12, 1991Date of Patent: April 13, 1993Assignee: The Wellcome Foundation LimitedInventors: Robert J. Blade, George S. Cockerill, John E. Robinston
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Patent number: 5202152Abstract: A substantially stoichiometric film of titanium nitride is provided by heating a substrate upon which a solution containing titanium has been applied at a substantially ambient temperature to provide a gel-film containing titanium on the surface of the substrate in an ammonia atmosphere. The substrate is heated to a temperature at which the titanium in the titanium-containing gel-film is substantially completely transformed to a substantially stoichiometric titanium nitride film, and at a rate of temperature change that is great enough to prevent the formation of nonstoichiometric titanium nitride compounds or other undesired titanium compounds in the resulting titanium nitride film. The invention is particularly suited for use in microelectronic devices.Type: GrantFiled: October 25, 1991Date of Patent: April 13, 1993Assignee: Cornell Research Foundation, Inc.Inventors: Emmanuel P. Giannelis, Joseph L. Keddie, Y. Y. Shacham-Diamond
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Patent number: 5200183Abstract: The complete structure of human milk BAL cDNA is disclosed. The nucleotide sequences of the cDNA inserts of two clones overlap and together contain 2951 base pairs of BAL cDNA which codes for an open reading frame of 742 amino acid residues between initiation and termination codons. There is a putative signal sequence of 20 residues which is followed by a 61-amino-terminal sequence of BAL. The cDNA sequence also contains a 678-base 5'-untranslated sequence, a 97-base 3'-untranslated region, and a 14-base poly(A) tail. The deduced BAL protein structure contains in the carboxyl-terminal region fourteen repeating unis of 11 amino acids each. The repeating units have the basic structure of Pro-Val-Pro-Pro-Thr-Gly-Asp-Ser-Gly-Ala-Pro-, with only minor substitutions.Type: GrantFiled: June 12, 1990Date of Patent: April 6, 1993Assignee: Oklahoma Medical Research FoundationInventors: Jordan J. N. Tang, Chi-Sun Wang
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Patent number: 5200338Abstract: A newly discovered lignin peroxidase enzyme is provided. The enzyme is obtained from a bacterial source and is capable of degrading the lignin portion of lignocellulose in the presence of hydrogen peroxide. The enzyme is extracellular, oxidative, inducible by lignin, larch wood xylan, or related substrates and capable of attacking certain lignin substructure chemical bonds that are not degradable by fungal lignin peroxidases.Type: GrantFiled: November 30, 1988Date of Patent: April 6, 1993Assignee: Idaho Research Foundation, IncorporationInventors: Donald L. Crawford, Muralidhara Ramachandra
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Patent number: 5199299Abstract: An ultrasonic unipolar pulse/echo instrument uses active switches and a timing and drive circuitry to control electrical energy to a transducer, the discharging of the transducer, and the opening of an electrical pathway to the receiving circuitry for the returning echoes. The active switches utilize MOSFET devices along with decoupling circuitry to insure the preservation of the unipolar nature of the pulses, insure fast transition times, and maintain broad band width and time resolution. A housing contains the various circuitry and switches and allows connection to a power supply and a movable ultrasonic transducer. The circuitry maintains low impedance input to the transducer during transmitting cycles, and high impedance between the transducer and the receiving circuit during receive cycles to maintain the unipolar pulse shape. A unipolar pulse is valuable for nondestructive evaluation, a prime use for the present instrument.Type: GrantFiled: March 11, 1991Date of Patent: April 6, 1993Assignee: Iowa State University Research Foundation, Inc.Inventors: Michael S. Hughes, David K. Hsu, Donald O. Thompson, Samuel J. Wormley
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Patent number: 5200050Abstract: An electrophoretic processor for separating proteins and other chemicals exhibiting varying electrophoretic mobilities. The preferred processor includes a rotor which turns within a stator to define a processing chamber therebetween. The rotor and stator are preferably cylindrical to provide an cylindrically annular processing chamber which will induce transverse secondary flows, preferably in the form of toroidal vortices. The transverse toroidal vortices improve heat transfer and counteract longitudinal flows which decrease separation. The processor can be provided with a process temperature stabilizer, such as a chamber surrounding the stator, through which a heat exchange fluid is passed. The processor can be used to perform a variety of processes including batch and continuous flow zone electrophoresis and batch isoelectric focusing.Type: GrantFiled: October 25, 1991Date of Patent: April 6, 1993Assignee: Washington State University Research FoundationInventors: Cornelius F. Ivory, William A. Gobie
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Patent number: 5200389Abstract: A method for manufacturing a superconducting article, comprising the steps of: forming a first layer comprising a mixture of LnBa.sub.2 Cu.sub.3 O.sub.x and Ln.sub.2 BaCuO.sub.x ' on the surface of a substrate, said Ln being an optional rare earth element; then forming a second layer comprising a mixture of at least CuO and BaCuO.sub.2 on the surface of the first layer; and then melting the mixture in the second layer to cause the resultant melt of the mixture in the second layer to diffusion-react with Ln.sub.2 BaCuO.sub.x ' in the first layer so as to convert the first and second layers into a film of a superconducting substance comprising LnBa.sub.2 Cu.sub.3 O.sub.x ; thereby manufacturing a superconducting article comprising the substrate and the film of the superconducting substance formed on the surface of the substrate.Type: GrantFiled: October 25, 1991Date of Patent: April 6, 1993Assignees: The Tokai University Juridicial Foundation, NKK CorporationInventors: Kyoji Tachikawa, Yukio Shinbo, Moriaki Ono, Shigeyoshi Kosuge, Makoto Kabasawa
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Patent number: 5200004Abstract: A high strength, light weight "in-situ" Ti-Y composite is produced by deformation processing a cast body having Ti and Y phase components distributed therein. The composite comprises elongated, ribbon-shaped Ti and Y phase components aligned along an axis of the deformed body.Type: GrantFiled: December 16, 1991Date of Patent: April 6, 1993Assignee: Iowa State University Research Foundation, Inc.Inventors: John D. Verhoeven, Timothy W. Ellis, Alan M. Russell, Lawrence L. Jones
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Patent number: 5200514Abstract: A method for the preparation of 2'-deoxynucleosides and 2',3'-dideoxy-2',3'-didehydronucleosides that includes the step of reacting a nucleoside having hydroxyl groups in the 2' and 3' positions with a mixture of acyl bromide or chloride and HX, wherein X is Br or Cl, at moderate temperature, to give a haloacyl nucleoside derivative that can be deprotected and reduced to form the desired compound.Type: GrantFiled: January 19, 1990Date of Patent: April 6, 1993Assignee: University of Georgia Research Foundation, Inc.Inventor: Chung K. Chu
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Patent number: 5199917Abstract: Through a silicon fabrication process, an emitter tip array is produced by electron beam or other suitable submicrometer scale lithography for precise location of the emitters. The emitter tips are formed by an oxidation process which ensures accurate and precise formation of tips having uniform radii. The process also utilizes the oxidation step to precisely align gate electrode apertures with respect to corresponding emitter tips so that large arrays can be formed with great accuracy and reliability.Type: GrantFiled: December 9, 1991Date of Patent: April 6, 1993Assignee: Cornell Research Foundation, Inc.Inventors: Noel C. MacDonald, James P. Spallas
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Patent number: 5200693Abstract: A method and apparatus for determining the carrier concentration and profile depth for pn semiconductor structures, and band discontinuities for heterojunction pn structures is disclosed. A more accurate measurement of carrier concentration and profile depth is obtained by initially measuring the pn junction intercept voltage of a pn semiconductor structure to be tested before the structure is exposed to a conventional capacitance-voltage (C-V) profiling process. The pn junction intercept voltage is employed to determine the pn junction capacitance which can then be compensated for in capacitance dependent formulae used for calculating the carrier concentration and profile depth. The intercept voltage can also be used to determine band discontinuities in a heterojunction pn structure. A fixed or retractable metal contact is employed to contact the p-type layer of a pn semiconductor structure to be tested and permit this initial measurement to be obtained.Type: GrantFiled: February 26, 1991Date of Patent: April 6, 1993Assignee: Cornell Research Foundation, Inc.Inventor: James Singletery, Jr.