Abstract: The invention relates to pharmaceutical compositions comprising at least one antigen and an adjuvant composition, where the adjuvant composition comprises a saponin and a liposome. The liposome of the composition comprises monophosphoryl lipid A (MPLA), cholesterol and a phospholipid that is in a liquid crystalline state at greater than or equal to 23° C., and the concentration of cholesterol to lipid in the liposome is greater than 50% (mol/mol). The antigen in the composition is a soluble Plasmodium falciparum recombinant circumsporozoite protein (rCSP) comprising the amino acid sequence of SEQ ID NO:1, or a P. falciparum rCSP peptide that is at least 95% identical to the amino acid sequence of SEQ ID NO:1.

Abstract: An optical filter includes a light absorbing layer and a conductive nanodisk. The light absorbing layer includes a near-infrared absorbing material configured to absorb light of a first wavelength spectrum within a near-infrared wavelength spectrum. The conductive nanodisk is configured to absorb or reflect light of a second wavelength spectrum within the first wavelength spectrum. An image sensor includes the optical filter, a camera module includes the optical filter, and an electronic device includes the optical filter.

Abstract: A method of tailoring the properties of garnet-type scintillators to meet the particular needs of different applications is described. More particularly, codoping scintillators, such as Gd3Ga3Al2O12, Gd3Ga2Al3O12, or other rare earth gallium aluminum garnets, with different ions can modify the scintillation light yield, decay time, rise time, energy resolution, proportionality, and/or sensitivity to light exposure. Also provided are the codoped garnet-type scintillators themselves, radiation detectors and related devices comprising the codoped garnet-type scintillators, and methods of using the radiation detectors to detect gamma rays, X-rays, cosmic rays, and particles having an energy of 1 keV or greater.

Abstract: Provided is a three-dimensional vertical memory device including: a semiconductor substrate, a vertical columnar channel region provided on the semiconductor substrate and having a void of a predetermined size therein; a source electrode and a drain electrode spaced apart from each other with the channel region interposed therebetween; and a gate stack formed on the channel region.

Abstract: This disclosure relates to the 5th generation (5G) or pre-5G communication system for supporting a higher data rate after the 4th generation (4G) communication system such as Long Term Evolution (LTE). The method for operating the core network in a wireless communication system according to this disclosure comprises the processes of determining the content to store in the terminal based on the location information of the terminal, transmitting the content transmission command to the base station so as to transmit the content to the terminal in response to the determination, checking whether the terminal has entered the overload cell, and forming a D2D communication link between the terminal and another adjacent terminal when it is identified that the terminal has entered the overload cell.

Abstract: The present invention relates to: a spectral leakage-based loopback method for a built-in self-test (BIST), achieving cost efficiency by accurately predicting the nonlinearity of a mixed-signal circuit in a loopback mode; and a system therefor, the method comprising the steps of: modeling a correlation by deriving the transfer function of a loopback path; generating a digitally synthesized single-tone sine wave input signal by means of an on-chip DSP core so as to sample same in a nonlinear DAC channel, and supplying a DAC output signal to a nonlinear ADC channel through an analog loopback path so as to measure each of the DAC channel and the ADC channel for a process test; and performing post-processing by means of the on-chip DSP core and predicting the harmonics of the two separate DAC and ADC channels.

Abstract: A host includes: an index tree storing an index including information for identifying a versioning key; and an index update buffer storing a write key included in data subject to a write request and the versioning key corresponding to the write key. When a preset update condition is satisfied, the host transfers the versioning key stored in the index update buffer to the index tree, and when the index update buffer requires recovery, the host designates a recovery section of memory of the storage device including data corresponding to the versioning key which has not been updated to the index tree, to be read by a plurality of threads, reads data included in the recovery section from the storage device through the plurality of threads, and inserts the read data into the index update buffer to recover the index update buffer.

Abstract: The capillary transfer technology presented here represents a powerful approach to transfer soft films from surface of liquid onto a solid substrate in a fast and defect-free manner. The fundamental theoretical model and transfer criteria validated with comprehensive experiments and finite element analyses, for the first time provides a quantitative guide and optimization for the choice of material systems, operating conditions and environments for scalable on-demand transfers with high yield. The intrinsically moderate capillary transfer force and externally selectable transfer direction offer robust capabilities for achieving deterministic assembly and surface properties of structures with complex layouts and patterns for potentially broad applications in the fabrication of flexible/stretchable electronics, surface wetting structures and optical devices.

Abstract: A method for predicting a structure of an indoor space using radio propagation channel analysis through deep-learning is disclosed. Channel data of radio signals are collected for various indoor spaces, and radio channel parameter data such as PDP, AoA, and AoD are extracted therefrom. A large amount of propagation channel parameter data is input to an artificial neural network together with vertex coordinate data of the corresponding indoor space and deep-learning is performed in advance. The propagation channel parameter data are extracted from the indoor space to be predicted, the best matching indoor space is detected based on the trained artificial neural network. The best matching indoor space is predicted as the structure of the indoor space.

Abstract: Systems and methods for self-cleaning a surface of an object where an electrodynamic shield is mounted to a surface of the object. The electrodynamic shield includes one or more sets of electrodes atop a substrate, at least one or more sets of electrodes being covered in a protective film. A coating is applied to the top surface of the protection film. A signal pulse generator is connected to the one or more sets of electrodes. The signal pulse generator generates a pulse signal that causes the one or more sets of electrodes to generate an electric field. The pulse signal comprises a plurality of different pulse signals which have phase differences between consecutive signals, and the electric field causes a particle atop the coating to experience an electrostatic force and be repelled away from the coating. These pulse signals (including shapes, amplitudes, shifts, and frequencies) can be tuned to increase efficiency of removal depending on dust type and relative humidity.

Abstract: A semiconductor device includes a multilevel receiver including a signal determiner receiving a plurality of multilevel signals and outputting a result of mutual comparison of the plurality of multilevel signals as an N-bit signal, where N is a natural number equal to or greater than 2. A decoder restores a valid signal among the N-bit signals from the signal determiner to an M-bit data signal, where M is a natural number less than N. A clock generator receives a reference clock signal, generates an input clock signal using the reference clock signal, inputs the input clock signal to the signal determiner, and determines a phase of the input clock signal based on an occurrence probability of an invalid signal not restored to the M-bit data signal among the N-bit signals.

Abstract: A nanohole template is disclosed which includes a substrate and a vertically aligned nanocomposite (VAN) structure disposed over the substrate. The VAN structure is a metal nitride having circular periodic nanoholes of about 2 nm to about 20 nm in diameter.

Abstract: There are provided a lithography method capable of selecting best resist and a semiconductor device manufacturing method and exposure equipment based on the lithography method. The lithography method includes estimating a shape of a virtual resist pattern based on a multi-scale simulation for resist, forming a test resist pattern by performing exposure on selected resist based on the simulation result, comparing the test resist pattern with the virtual resist pattern, and forming a resist pattern on an object to be patterned by using the resist when an error between the test resist pattern and the virtual resist pattern is in an allowable range.

Abstract: Disclosed herein are recombinant AAV variant (e.g., variant serotype 3B (AAV3B)) capsid proteins and variant capsid protein-containing viral particles with enhanced ability to transduce hepatic cells. Viral particles containing these capsid variants are capable of evading neutralization by the host humoral immune response. The recombinant AAV3B variant proteins and viral particles disclosed herein were identified from a variant AAV3B capsid library that was engineered by making substitutions in only the variable regions of the capsid. Some embodiments of the AAV3B capsid variants disclosed herein comprise the AAV3B-G3 variant and the AAV3B-E12 variant. Compositions of these variant AAV particles are provided that are useful for transducing and delivering therapeutic transgenes to cells, such as liver cells, and thus treat diseases and disorders pertaining to these cells.

Abstract: Compositions and methods for the treatment of malignancy are disclosed.

Abstract: Peptides and conjugates are described herein, including peptides having antimicrobial and/or anticancer properties, as are compositions, articles, and kits comprising such peptides and conjugates, and methods for using the peptides and conjugates.

Abstract: A substrate bonding apparatus for bonding a first substrate to a second substrate includes a first bonding chuck supporting the first substrate, a second bonding chuck disposed above the first bonding chuck and supporting the second substrate, a resonant frequency detector detecting a resonant frequency of a bonded structure with the first substrate and the second substrate which are at least partially bonded to each other, and a controller controlling a distance between the first bonding chuck and the second bonding chuck according to the detected resonant frequency of the bonded structure.

Abstract: A handover method for managing WBSS vehicle network managed by a WESS-CM includes: recognizing that a vehicle enters an overlapped area between first and second WBSSs; sending, by the first WBSS, a handover recommend request to the WESS-CM; confirming with the second WBSS, by the WESS-CM, whether handover is possible; responding to the WESS-CM, by the second WBSS, the availability of the handover after allocating communication resources; sending, by the WESS-CM, a handover recommend response to the first WBSS; transmitting, by the first WBSS, a handover request message to the vehicle; performing the handover, by the vehicle, by performing reassociation with the second WBSS; and periodically broadcasting, by the vehicle, basic safety message using a T-slot in shared control channel and a T-slot in BSM channel for the second WBSS, while the vehicle is located in the overlapped area.

Abstract: The present invention generally provides methods and compositions for the treatment of Parkinson's disease and depression and/or anxiety. The invention relates to recombinant microorganisms, particularly gut-colonizing probiotics, modified to produce L-DOPA.

Abstract: Devices and methods for assisting breathing in a subject are described. In one embodiment, a device includes a splint that can be used to apply negative distending pressure, i.e., outward pull, to one or both of the chest walls and/or the abdomen of a subject. The splint may include an air bladder that can be attached to the skin of the subject's chest and/or abdomen. When the air bladder is inflated, negative distending pressure is applied to the subject's chest and/or abdomen, thereby assisting or promoting respiration. The inflated air bladder may also apply a compressive force on the chest to facilitate expiration, and the removal of secretions in the airways.