Abstract: A high-resolution x-ray imaging system encodes spatial information into x-ray energy by an encoding filter which changes the x-ray energy sensitivity of each detector at different portions of the detector. Acquiring successive images at different energies allows the fluence at different portions of a single detector to be isolated providing effective sub detector resolution.
Abstract: A network switch holds a routing table and a network topology table so that when a link failure is detected at the network switch, the network switch may independently reroute a packet intended for that failed link using the network topology table. This processing can be performed in the data plane at a speed that can eliminate dropped packets. Intercommunication with a central controller is not required and intercommunication with other network switches may be accomplished through data plane communication by embedding the link failure information in the affected packet.
Abstract: A display apparatus includes a display panel; a touch sensing unit (TSU) on the display panel and including first and second transmission touch lines (TTL); and a touch driving circuit (TDC). The TDC applies first and second touch driving signals (TDS) to the first and second TTL, respectively. The TDC includes first and second sharing switch devices (SSD) respectively connected to the first and second TTL. The first and second SSD are connected to each other. The first TDS has a first voltage level during a first period, and the second TDS has a second voltage level different than the first voltage level during the first period. The TDC is configured to turn on the first and second SSD during a second period after the first period such that the first and second TDSs have a voltage level between the first voltage level and the second voltage level.
Type:
Grant
Filed:
August 8, 2018
Date of Patent:
July 27, 2021
Assignees:
Samsung Display Co., Ltd., Seoul National University R&DB Foundation
Inventors:
Youngmin Park, Deog-kyoon Jeong, Kyungyoul Min, Jiheon Park, Jonghyun Oh, Moonsang Hwang, Young-Ha Hwang
Abstract: Analogues of an alternatively spliced form of atrial natriuretic peptide (MANP) that exhibit pGC-A gain of function and can be used to treat cardiorenal and metabolic disease are described herein.
Type:
Grant
Filed:
November 9, 2017
Date of Patent:
July 27, 2021
Assignee:
Mayo Foundation for Medical Education and Research
Abstract: Disclosed herein are multifunctional polypeptides comprising a first domain comprising an anti-tau antigen binding domain and a second domain comprising a proteasome-targeting PEST motif, and methods for using these polypeptides in treatment of tauopathies.
Type:
Grant
Filed:
September 8, 2017
Date of Patent:
July 27, 2021
Assignee:
Regenerative Research Foundation
Inventors:
Sally Temple, Anne Messer, David Butler
Abstract: When using a pharmaceutical composition for preventing or treating malignant hyperthermia, containing NAADP antagonists, of the present invention, malignant hyperthermia can be effectively prevented or treated through the inhibition of an oxygen consumption rate abnormal increase, which is associated with a ryanodine receptor (RYR) of skeletal muscles. In addition, the present invention can be used even after the onset of malignant hyperthermia and can inhibit an oxygen consumption rate abnormal increase even at concentrations lower than those of conventional agents for treating malignant hyperthermia, thereby enabling conventional agents for treating malignant hyperthermia to be replaced, and can be stably used, thereby being effectively usable in relevant industries.
Type:
Grant
Filed:
October 11, 2017
Date of Patent:
July 27, 2021
Assignee:
Industrial Cooperation Foundation Chonbuk National University
Inventors:
Uh Hyun Kim, Dae Ryoung Park, Kwang Hyun Park
Abstract: Provided are aromatic oligoamide foldamers and self-assembled compositions of the same. The aromatic oligoamide foldamers and compositions can form tube-like structures that can form pores in membranes. The pores can be used to transport ions and molecules, such as, for example, cryoprotective agents or therapeutic agents, through the membrane. The tube-like structures exhibit desirable stability at low temperatures.
Type:
Grant
Filed:
February 26, 2020
Date of Patent:
July 27, 2021
Assignee:
The Research Foundation for The State University of New York
Abstract: Disclosed are an apparatus for controlling vehicle platooning and a method thereof. The apparatus includes a communication device that receives estimated acceleration from a leading vehicle, a radar sensor that measures acceleration of a preceding vehicle, and a controller that calculates corrected acceleration by using the estimated acceleration received from the leading vehicle and the acceleration (hereinafter, referred to as a measured acceleration) of the preceding vehicle measured by the radar sensor and controls the vehicle platooning based on the corrected acceleration.
Type:
Grant
Filed:
April 24, 2019
Date of Patent:
July 27, 2021
Assignees:
Hyundai Motor Company, Kia Motors Corporation, Korea University Research and Business Foundation
Inventors:
Hong Gi Park, Hyoung Jong Wi, Dae Hie Hong
Abstract: Methods for ex vivo expansion of very small embryonic like stem cells in the absence of feeder cells are provided. In some embodiments the methods include providing a plurality of VSELs; and growing the VSELs in a culture medium that includes a histone deacetylase inhibitor, luteinizing hormone, follicle-stimulating hormone, and optionally transforming growth factor beta in an amount that is sufficient to overcome quiescence of the VSELs. Also provided are feeder cell-free cell cultures, ex vivo expanded VSELs, pharmaceutical compositions that include the disclosed ex vivo expanded VSELs, methods for overcoming quiescence in VSELs, methods for re-establishing imprinting in VSELs, method for treating injuries to tissues in subjects, methods for repopulating cell types in subjects, methods for bone marrow transplantation, methods for treating radiation exposure in subjects, and methods that relate to regenerative medicine.
Type:
Grant
Filed:
March 3, 2017
Date of Patent:
July 27, 2021
Assignee:
University of Louisville Research Foundation, Inc.
Inventors:
Mariusz Z. Ratajczak, Janina Ratajczak, Magdalena Kucia, Donald Miller
Abstract: An automatic cardiopulmonary resuscitation device includes a movable chest compressor for repeatedly pressing a patient's chest at a preset depth and cycle, a cardiac output measurement unit for measuring a cardiac output of the patient in accordance with the pressurization of the chest compressor and a processor for changing pressing locations by performing control such that the chest compressor moves according to a preset method.
Type:
Grant
Filed:
January 26, 2017
Date of Patent:
July 27, 2021
Assignee:
Seoul National University R&DB Foundation
Inventors:
Gil Joon Suh, Woon Yong Kwon, Kyung Su Kim, Sang Hoon Na, Jaeheung Park, Jung Chan Lee, Yoon Sun Jung, Kyoung Min You, Min Ji Park, Taegyun Kim, Jung-In Ko, Jeeseop Kim, Jaesug Jung, Sanghyun Kim, Byeong Wook Yoo, Byeongtak Lee, Woo Sang Cho, Jin Woo Choi
Abstract: A method of controlling a data center having a cold air cooling system, and at least one containment structure, comprising: determining a minimum performance constraint; determining optimum states of the cold air cooling system, a controlled leakage of air across the containment structure between a hot region and a cold air region, and information technology equipment for performing tasks to meet the minimum performance constraint, to minimize operating cost; and generating control signals to the cold air cooling system, a controlled leakage device, and the information technology equipment in accordance with the determined optimum states.
Type:
Grant
Filed:
January 24, 2018
Date of Patent:
July 27, 2021
Assignee:
The Research Foundation for the State University
Abstract: The invention generally relates to two-dimensional mass spectrometry using ion micropacket detection. In certain aspects, the invention provides systems including a mass spectrometer having an ion trap and one or more detectors. The system includes a central processing unit (CPU), and storage coupled to the CPU for storing instructions that when executed by the CPU cause the system to: apply one or more scan functions to the ion trap that excite a precursor ion and eject a product ion from the ion trap; and determine a secular frequency of the product ion by detecting micropackets of the product ion as the micropackets are ejected from the ion trap.
Type:
Application
Filed:
May 23, 2019
Publication date:
July 22, 2021
Applicant:
Purdue Research Foundation
Inventors:
Robert Graham Cooks, Dalton Snyder, Lucas Szalwinski
Abstract: Provided herein are methods and compositions useful in the production of recombinant AAV (rAAV) in insect cells. In some embodiments, methods and compositions include the use of modified Kozak sequences to express AAV VP1 proteins in amounts that are useful for producing infective rAAV particles.
Type:
Application
Filed:
April 16, 2017
Publication date:
July 22, 2021
Applicant:
University of Florida Research Foundation, Incorporated
Abstract: Provided herein are methods for generating a non-naturally occurring, broadly reactive, pan-epitopic antigen derived from H3 influenza virus that is capable of eliciting a broadly reactive immune response, such as a broadly reactive neutralizing antibody response, against H3 virus following administration to a subject. Also provided is a non-naturally occurring immunogen generated using the methods, and vaccines and compositions comprising the immunogen. Methods of generating an immune response in a subject by administering the immunogen, vaccine, or composition are provided. In particular, the immunogen comprises the hemagglutinin (HA) protein of H3 influenza vims strains.
Type:
Application
Filed:
July 12, 2019
Publication date:
July 22, 2021
Applicant:
University of Georgia Research Foundation
Inventors:
James Daniel Allen, Ted Milburn Ross, Terianne Maiko Wong
Abstract: A heart valve therapeutic device (1) comprises a coaptation assist valve (20) comprising a conduit (2) with an outer surface (3) for coaption with the native leaflets, and a prosthetic flow valve (5) mounted within the conduit (2) to allow one-way flow through the conduit (2). Support for the coaptation assist valve (20) is provided by a support (10) for positioning the conduit (2) across the native leaflets, and connectors (15) attaching the conduit (2) to the support (10).
Type:
Application
Filed:
March 18, 2021
Publication date:
July 22, 2021
Applicant:
The Provost, Fellows, Foundation Scholars, And The Other Members Of Board, Of The College Of The Ho
Inventors:
Paul HENEGHAN, Bruce MURPHY, Lucy O'KEEFFE, Martin QUINN, Conor QUINN
Abstract: Provided herein are aptamers capable of inhibiting the activity of Von Willebrand Factor (VWF). Pharmaceutical compositions comprising these aptamers are also provided. Methods of preventing blood clot formation in a subject by administering the aptamers are provided and methods of treating a blood clot by administering a VWF-targeting agent are also provided.
Type:
Application
Filed:
January 11, 2021
Publication date:
July 22, 2021
Applicants:
Duke University, Ohio State Innovation Foundation
Inventors:
Shahid M. NIMJEE, Bruce SULLENGER, George A. PITOC, Juliana LAYZER
Abstract: A wearable chair may include a foot frame configured to support a foot of a user; a shank link configured to rotatably connect to the foot frame; a connecting link provided in front of the shank link and configured to rotatably connect to the foot frame; a knee link configured to rotatably connect to each of the shank link and the connecting link; and a thigh link configured to extend from the knee link. The foot frame, the shank link, the connecting link, and the knee link constitute a four-bar linkage.
Type:
Application
Filed:
April 5, 2021
Publication date:
July 22, 2021
Applicants:
Samsung Electronics Co., Ltd., Korea University of Technology and Education Industry-University Cooperation Foundation
Abstract: Disclosed is a method for synthesizing a single crystal transition metal dichalcogenide thin film. The method includes processing a surface of a metal substrate such that a high index surface having a Miller index of (hkl) is exposed; and synthesizing a single crystal transition metal dichalcogenide on the high index surface using a chemical vapor deposition, wherein each of h, k, and l is independently an integer, and at least one of h, k, and l is an integer greater than or equal to +2 or smaller than or equal to ?2.
Type:
Application
Filed:
January 20, 2021
Publication date:
July 22, 2021
Applicant:
Research & Business Foundation Sungkyunkwan University