Abstract: Various embodiments disclosed relate to a sensor assembly probe for determining enzymatic activity. The sensor assembly probe includes one or more fluorescent hydrophobic semi-conductive nanoparticles disposed in an aqueous medium. The assembly further includes an amphiphilic polymer including a substrate for a predetermined enzyme. The amphiphilic polymer coats at least a portion of a surface of the fluorescent hydrophobic semi-conductive nanoparticle.

Abstract: A system, methods, and techniques are provided for performing automated operations to track one or more physiological indicators of a user via hardware capabilities of a computing device associated with the user, and/or of external monitoring devices communicatively coupled to such a user computing device. Feedback regarding such tracked activities may be provided to the user via one or more guided physiological and/or exercises. The system may enable the user to interactively create and/or experience audiovisual artworks that may include still images, music, dynamic sound effects, and animations, such as animations depicting the creation of one or more related artworks.

Abstract: Various examples are provided for in situ growth of subsurface structures using bioinspired mineralization. In one example, among others, a method for growth of a subsurface structure includes introducing a first aqueous mineral salt reactant and a second aqueous mineral salt reactant comprising a polymeric additive into a soil substrate. The first and second aqueous mineral salt reactants can combine to form a polymer-induced liquid-precursor (PILP) phase that initiates in situ mineralization in the soil substrate. Solidifying the mineralization can form a subsurface structure in the soil substrate. Multiple applications of aqueous mineral salt reactants can be introduced to adjust the thickness of the mineralization or for layers of coatings.

Abstract: The present invention provides a non-destructive method of characterizing CMAS infiltration and CMAS assisted damage in thermal barrier coatings (TBCs). Such approach is especially relevant for determining the lifetime of coatings on e.g. turbines or parts of the turbines such as blades or in-liners of the combustion chambers. The turbines can be gas turbines or high-pressure turbines or others and may be stationary or used for example in aviation.

Abstract: A method for testing system-on-a-chip (SoC) for faults at subthreshold or substantially at threshold operating voltages includes the steps of testing the SoC for fault at a favorable operating voltage, the testing including measuring a metric characterizing the fault at the favorable operating voltage to obtain a first metric value; and retesting the SoC for the fault at a first operating voltage upon the first metric value at the favorable operating voltage being correlated, according to a metric correlation establishing a correlation relationship between the favorable operating voltage and the first operating voltage, to a second metric value at the first operating voltage within a predictive interval of the metric correlation.

Abstract: A compound of Formula 1: Li1+2x?yZn1?xPS4?y??Ay??(1) wherein A is halogen, 0?x?1, 0?y?0.5, and 0???0.5, and wherein the compound of Formula 1 has an body centered cubic crystal structure. Also a lithium battery and an electrode including the compound.

Abstract: A method of emitting photons at a desired wavelength, including: providing a material having a first region of high absorption of radiation at a first set of wavelength of radiation, contiguous with a second region of low absorption of radiation at a shorter set of wavelengths, and a third region of high emission at a further shorter set of wavelengths; applying energy to the material at the first region, such that most of an effective black body radiation of said material at a temperature of the material would fall within the second region and be configured to transfer energy to said third region and not overlap with the first region; and emitting energy from the material at the third region, powered by said applying energy.

Abstract: A non-transitory computer-readable medium encoded with a computer-readable program, which when executed by a processor, will cause the processor to execute an image processing method, the image processing method including establishing a zero crossing region from a target image onto a screen, wherein the zero crossing region comprises a corresponding value. The method further includes receiving a variable input and an integration time input, wherein the variable input comprises a frequency number for an image accumulation procedure, and wherein the integration time comprises a time period for which an aperture for a sensor receives incoming signals. Additionally, the method includes performing the image accumulation procedure. Moreover, the method includes producing a final greyscale image by adding a plurality of sets of vertically shifted pixel values, wherein the frequency number for the image accumulation procedure ranges from 3 to 20.

Abstract: A heart valve therapeutic device (1) comprises a coaptation assist valve (20) comprising a conduit (2) with an outer surface (3) for coaption with the native leaflets, and a prosthetic flow valve (5) mounted within the conduit (2) to allow one-way flow through the conduit (2). Support for the coaptation assist valve (20) is provided by a support (10) for positioning the conduit (2) across the native leaflets, and connectors (15) attaching the conduit (2) to the support (10).

Abstract: A sensor including a layer of amorphous selenium (a-Se) and at least one charge blocking layer is formed by depositing the charge blocking layer over a substrate prior to depositing the amorphous selenium, enabling the charge blocking layer to be formed at elevated temperatures. Such a process is not limited by the crystallization temperature of a-Se, resulting in the formation of an efficient charge blocking layer, which enables improved signal amplification of the resulting device. The sensor can fabricated by forming first and second amorphous selenium layers over separate substrates, and then fusing the a-Se layers at a relatively low temperature.

Abstract: The present disclosure provides nucleic acid compositions that incorporate one or more halouracil molecules. More specifically, the present disclosure reveals that the replacement of uracil nucleotides within a microRNA nucleotide sequence with a 5-halouracil increases the ability of the micro-RNA to inhibit cancer progression and tumorigenesis. As such, the present disclosure provides various nucleic acid (e.g., microRNA) compositions having 5-halouracil molecules incorporated in their nucleic acid sequences and methods for using the same. The present disclosure further provides pharmaceutical compositions comprising the modified nucleic acid compositions, and methods for treating cancers using the same.

Abstract: Provided is a negative differential resistance element having a 3-dimension vertical structure. The negative differential resistance element having a 3-dimension vertical structure includes: a substrate; a first electrode that is formed on the substrate to receive a current; a second semiconductor material that is formed in some region of the substrate; a first semiconductor material that is deposited in some other region and the first electrode of the substrate and some region of an upper end of the second semiconductor material; an insulator that has a part vertically erected from the substrate, the other part vertically erected from the second semiconductor material, and an upper portion stacked with a first semiconductor material; and a second electrode that is formed at an upper end of the second semiconductor material to output a current, thereby significantly reducing an area of the device and greatly improving device scaling and integration.

Abstract: A branched and fenestrated prosthesis may include a main tubular graft body including a proximal end opening, a distal end opening, a lumen, and a sidewall. A branch may extend from the sidewall and may include a first end opening, a second end opening, and a lumen. A fenestration may be disposed in the sidewall and positioned distal of the second end opening of the branch. The branched and fenestrated prosthesis may include a plurality of branches and a plurality of fenestrations.

Abstract: The present invention provides antibodies that target glioblastoma stem-like cells and methods and kits for their use.

Abstract: A delta-sigma modulator generates a bit stream signal from an analog signal by operating according to a modulation period including a sampling period and a filtering period and includes a digital-to-analog converter (DAC) configured to generate a charge signal according to one of a first reference voltage and a second reference voltage according to the bit stream signal during the sampling period and to output a signal generated according to the charge signal and the other of the first reference voltage and the second reference voltage; a loop filter configured to charge a sampling signal corresponding to the analog signal during the sampling period and to filter an output from the DAC and a signal generated according to the sampling signal during the filtering period; and a quantizer configured to generate the bit stream signal according to an output from the loop filter in the modulation period.

Abstract: The present disclosure relates to a self-assembled nanostructure of an elastin- and resilin-based block copolypeptide with stimuli responsiveness and resilience for drug delivery, tissue engineering and regenerative medicine, a method for preparing the same and application thereof. The diblock polypeptide reversibly forms a self-assembled micelle structure in response to temperature stimuli and a hydrogel prepared using the triblock polypeptide undergoes reversible sol-gel or gel-sol transition in response to temperature stimuli and exhibits enhanced mechanical strength due to chemical crosslinkages between tyrosine residues. With such superior properties, the diblock/triblock polypeptide of the present disclosure can be used for drug delivery systems, scaffolds for tissue engineering and kits for tissue or organ regeneration.

Abstract: The present invention provides a memory device in which a lower electrode, a seed layer, synthetic antiferromagnetic layers, a separation layer, a magnetic tunnel junction, a capping layer, and an upper electrode are formed on a substrate in a laminated manner, wherein a diffusion barrier is formed between the magnetic tunnel junction and the capping layer. In addition, the present invention provides a memory device in which a lower electrode, a seed layer, synthetic antiferromagnetic layers, a separation layer, a magnetic tunnel junction, a capping layer, and an upper electrode are formed on a substrate in a laminated manner, wherein the seed layer is formed of a material that allows the synthetic antiferromagnetic layers to grow in the FCC (111) direction.

Abstract: A first fiber is connected to a first end of a third fiber doped with a rare earth element, and a second fiber is connected to a second end of the third fiber. In the third fiber doped with the rare earth element, a central portion of a core is more heavily doped with the rare earth element than a peripheral portion of the core is.

Abstract: An information processing device for performing performance control in a virtualized environment is disclosed. The information processing device can include an I/O thread configured to transfer signals between a virtual machine and at least one physical resource, and a performance manager unit configured to compare a target performance for the virtual machine with an actual performance of the virtual machine and manage a resource allocated to the I/O thread based on the comparison result, where the performance manager unit may obtain information regarding the actual performance of the virtual machine, determine a performance adjustment value by using the difference between the actual performance of the virtual machine and the target performance for the virtual machine, and manage the resource allocated to the I/O thread based on the performance adjustment value.

Abstract: The present invention relates to a device and a method for detecting a peak of an intracranial pressure (ICP) waveform using a morphological feature of an arterial blood pressure waveform.