Abstract: Systems and methods are disclosed to determine the axial and/or lateral location of a particle using light modulated with temporal and/or spatial modulation pattern. The system, for example, may include a modulator configured to temporally modulate an intensity pattern of a line of light uniquely at each point along a lateral length of the line of light and produce an undiffracted modulated line of light, a first first-order diffracted line of light, and a second first-order diffracted line of light; and one or more optical elements configured to direct the undiffracted line of light and one of the first first-order diffracted line of light and the second first-order diffracted line of light toward at least one particle disposed at or near a sample region. The system may include a processor configured to determine an axial and/or a lateral position of the particle disposed at or near the sample region.
Type:
Grant
Filed:
March 24, 2015
Date of Patent:
September 11, 2018
Assignee:
Colorado State University Research Foundation
Inventors:
Randy Bartels, Jeffrey J. Field, David G. Winters
Abstract: Provided herein is a composite, comprising: a polymer host selected from the group consisting of low-density polyethylene (LDPE), linear low-density polyethylene (LLDPE), polyethylene terephthalate (PET), polytetrafluoroethylene (PTFE), and polypropylene (PP), polyurethane, polycaprolactone (PCL), polydimethylsiloxane (PDMS), polymethylmethacrylate (PMMA), and polyoxymethylene (POM); and a guest molecule comprising hyaluronic acid; wherein the guest molecule is disposed within the polymer host, and wherein the guest molecule is covalently bonded to at least one other guest molecule. Also provided herein are methods for forming the composite, and blood-contracting devices made from the composite, such as heart valves and vascular grafts.
Type:
Grant
Filed:
March 11, 2013
Date of Patent:
September 11, 2018
Assignee:
Colorado State University Research Foundation
Inventors:
Susan P. James, Harold Dean, IV, Lakshmi Prasad Dasi, Marcio H. Forleo, Ketul C. Popat, Nicole R. Lewis, David Alois Prawel
Abstract: Provided is a non-surgical method of treatment of carpal tunnel syndrome by administering an effective amount of purified collagenase I and II by injection onto a transverse carpal ligament, without penetrating the transverse carpal ligament. The purified collagenase I and II are obtained from Clostridium histolyticum, and the effective amount is a dose comprising a concentration of approximately 0.29 mg of the purified collagenase I and II to one ml diluent.
Type:
Grant
Filed:
January 5, 2016
Date of Patent:
September 11, 2018
Assignee:
The Research Foundation for The State University of New York
Abstract: A lens flare generation method and apparatus simulates lens flare effects through paraxial approximation-based linear approximation to generate a lens flare utilizing physical characteristics of a lens system while generating a lens flare at high speed. A non-linear effect may be added to a linear pattern-based lens flare effect to generate an actual lens flare reflecting most of physical characteristics generated from the lens system. A pre-recorded non-linear pattern may be used.
Type:
Grant
Filed:
January 23, 2017
Date of Patent:
September 11, 2018
Assignee:
Research & Business Foundation Sungkyunkwan University
Abstract: This document provides methods and materials for treating endometrial cancer. For example, methods and materials for identifying a female mammal as having endometrial cancer and surgically removing at least the uterus of the female are provided.
Type:
Grant
Filed:
March 27, 2015
Date of Patent:
September 11, 2018
Assignee:
Mayo Foundation for Medical Education and Research
Inventors:
Andrea Mariani, Nicholas Chia, Marina R. Walther-Antonio
Abstract: There is provided a three-dimensional triboelectric energy generator comprising: a moving object; at least two triboelectric energy generator modules defining at least two planes respectively, wherein the moving object is disposed between the least two planes; and at least two elastic members configured to couple the moving object to the at least two triboelectric energy generator modules respectively, wherein a movement of the moving object allows each of the at least two triboelectric energy generator modules to generate a triboelectric energy.
Type:
Grant
Filed:
June 8, 2016
Date of Patent:
September 11, 2018
Assignee:
Research & Business Foundation Sungkyunkwan University
Inventors:
Sang Woo Kim, Kwon Hoon Han, Seong Su Kim, Wan Chul Seung, Sung Kyun Kim
Abstract: An electrode for a lithium secondary battery including a silicon-based alloy having an expansion coefficient of 10% or greater and an electrochemically inactive whisker, and a lithium secondary battery using the electrode for a lithium secondary battery.
Type:
Grant
Filed:
May 27, 2014
Date of Patent:
September 11, 2018
Assignees:
Samsung SDI Co., Ltd., SNU R&DB Foundation
Inventors:
Jae-Hyuk Kim, Young-Ugk Kim, Seung-Uk Kwon, Soon-Sung Suh, Hee-Young Chu, Duk-Hyoung Yoon, Chang-Ui Jeong, Yo-Han Park, Kyu-Hwan Oh, Seoung-Bum Son, Seul-Cham Kim, Chan-Soon Kang
Abstract: The invention provides a method of removing or reducing undifferentiated cells from a differentiated cell population contaminated or having a risk of contamination with undifferentiated cells by contacting a pigment epithelium-derived factor with the differentiated cell population to induce apoptosis of the undifferentiated cells. The invention also provides an agent for cell transplantation therapy, containing a differentiated cell population substantially free of an undifferentiated cell, which is obtained by the method, as well as an agent for inducing apoptosis of an undifferentiated cell, containing a pigment epithelium-derived factor, and combined use of the aforementioned agent for cell transplantation therapy and the aforementioned agent for inducing apoptosis.
Type:
Grant
Filed:
March 25, 2014
Date of Patent:
September 11, 2018
Assignee:
Foundation for Biomedical Research and Innovation at Kobe
Abstract: An isolation and detection method for viruses from large quantities of water or other aqueous media. The technology employs charged resins to isolate viral particles from liquid sources such as water, milk, juices, and homogenized food. Anionic resin beads are added to a sample liquid and suspended within the liquid. While in suspension the anionic beads complex with negatively charged virus particles of other pathogens. The complexed beads are then removed from the liquid, effecting the isolation of the virus. Detection techniques can then be performed directly on the complexed beads without resorting to additional steps to elute the virus or other pathogen from the bead. The methodology can be employed for the detection of bacteriophage in an aqueous medium where the bacteriophage serves as a surrogate for the presence of a pathogen or other contaminant, such as an enteric virus.
Type:
Grant
Filed:
January 25, 2010
Date of Patent:
September 11, 2018
Assignee:
Colorado State University Research Foundation
Abstract: A soil sensor includes a housing, an antenna disposed within the housing, a measurement circuit disposed within the housing and operatively connected to the antenna, the circuit configured to measure impedance of soil at a plurality of different frequencies using the antenna as a sensor electrode, and a wireless interface disposed within the housing and operatively connected to the antenna and configured for wireless communications over the antenna at its communications frequency.
Type:
Grant
Filed:
April 24, 2015
Date of Patent:
September 11, 2018
Assignee:
Iowa State University Research Foundation, Inc.
Inventors:
Ratnesh Kumar, Robert J. Weber, Gunjan Pandey
Abstract: Provided herein are a thermoelectric material and a method for preparing the same, wherein the thermoelectric material has excellent thermoelectric performance and high mechanical properties (in particular, fracture toughness), and thus, when the thermoelectric material is applied to a thermoelectric module, the thermoelectric module has excellent performance and efficiency and a long lifespan.
Type:
Grant
Filed:
May 25, 2017
Date of Patent:
September 11, 2018
Assignees:
Hyundai Motor Company, Kia Motors Corporation, Industry-Academic Cooperation Foundation,Yonsei University
Inventors:
Byung Wook Kim, Jong Kook Lee, Han Saem Lee, In Woong Lyo, Jin Woo Kwak, Woo Young Lee, Gwan Sik Kim, Hwi Jong Lee
Abstract: A device and method for sensing including a sensor having a functional surface layer located to interact with a material to be sensed, the sensor having an output that produces a signal responsive one or more of inertia, stiffness, acceleration, pressure, radiation, chemical compounds, and biological compounds; and further including electronics including: an input coupled to the sensor to receive a first signal therefrom; and a non-linearity provider that applies one or more non-linear operations to the input signal to generate a non-linear second signal.
Type:
Grant
Filed:
February 7, 2018
Date of Patent:
September 11, 2018
Assignee:
Purdue Research Foundation
Inventors:
Jeffrey Frederick Rhoads, George Tsu-Chih Chiu, Nikhil Bajaj, Andrew Burke Sabater
Abstract: Disclosed are various embodiments for assessing machine trajectories for collision avoidance. A three-dimensional model of a patient based at least in part on data received from a three-dimensional imaging device is generated. The three-dimensional model of the patient is aligned with a coordinate system of a three-dimensional model of a radiation treatment machine. It is then determined whether a collision between the patient and the radiation treatment machine will occur at each one of a series of control points of the radiation treatment plan.
Abstract: The present invention relates to a pharmaceutical composition for preventing, treating or delaying an Alzheimer's disease (AD) or dementia including a G protein-coupled receptor19 (GPCR19) agonist or its pharmaceutically acceptable salt as an active ingredient and a food composition for preventing, treating or delaying an Alzheimer's disease or dementia. The GPCR19 agonist according to the present invention has an effect of improving cognitive and behavioral disorders without harming the health of objects when administrated to the objects and has an effect of preventing the Alzheimer's disease or dementia or delaying or treating the progression of the disease in the objects with the disease by suppressing apoptosis of the brain tissue, enhancing immunity, and reducing formation of an amyloid ? (A?) plague.
Type:
Grant
Filed:
January 15, 2016
Date of Patent:
September 11, 2018
Assignee:
Seoul National University R&DB Foundation
Inventors:
Seung Yong Seong, Jung Ah Cho, Tae Joo Kim, Youn Hee Kim
Abstract: Methods for enhancing production of a cellulose component are disclosed herein.
Type:
Grant
Filed:
September 9, 2015
Date of Patent:
September 11, 2018
Assignees:
Purdue Research Foundation, Federal University of Sao Carlos, Brazilian Agricultural Research Corporatio—Embrapa
Inventors:
Michael Ralph Ladisch, Eduardo de Aquino Ximenes, Thomas Richard Kreke, Alberto Colli Badino, Jr., Fernanda Marisa da Cunha, Cristiane Sanchez Farinas
Abstract: A method of designing and manufacturing a replica composite object based on an original object. The method identifies the structure and physical properties of an original object. Base materials, bodies, and structural templates, each of which includes associated physical properties, are utilized to generate a 3-dimensional model. The 3-dimensional model is discretized and tested to determine if the selected combination of base materials and bodies have physical properties that substantially equal the physical properties of the original object. If the physical properties do not equate, the 3-dimensional model is optimized by adjusting the combination of base materials, bodies, and structural templates. When the difference between the measured physical properties of the 3-dimensional model and the identified physical properties of the original object is less than a tolerance value, the method instructs an additive manufacturing system to generate a replica composite object based on the original object.
Type:
Grant
Filed:
February 13, 2018
Date of Patent:
September 11, 2018
Assignee:
University of Central Florida Research Foundation, Inc.
Abstract: This invention provides a device for implantation directly into the spinal cord for the purpose of treating back pain. Electrodes on a backing that conforms directly to the spinal cord are installed as a source of electrical stimulation and pain relief. The floating electrodes can be flexibly mounted to the substrate such that when the electrode array is implanted into the subject, individual electrodes float or move resiliently relative to the substrate to an extent sufficient to accommodate pulsations of the surface of the spinal cord within the dura.
Type:
Grant
Filed:
February 21, 2017
Date of Patent:
September 11, 2018
Assignees:
University of Iowa Research Foundation, University of Virgina Patent Foundation
Inventors:
Matthew A. Howard, Hiroyuki Oya, Steve Viljoen, Chandan G. Reddy, George T. Gillies