Patents Assigned to Foundation
  • Optical devices and methods of controlling propagation directions of light from the optical devices
    Patent number: 9499400
    Abstract: An optical device may include a substrate, a metal layer on the substrate, at least one first nano-structure in the layer, and at least one second nano-structure in the layer. The at least one first nano-structure may include a light source. The at least one first and second nano-structures may be spaced apart. A method of controlling a propagation direction of light output from an optical device that includes a metal layer on a substrate may include disposing first and second nano-structures in the layer; disposing at least one light source in the first nano-structure; and controlling the propagation direction of the light output from the at least one light source by changing at least one of a shape of the first nano-structure, a shape of the second nano-structure, a size of the first nano-structure, a size of the second nano-structure, and an interval between the first and second nano-structures.
    Type: Grant
    Filed: July 16, 2012
    Date of Patent: November 22, 2016
    Assignees: Samsung Electronics Co., Ltd., Korea Universisty Industrial & Academic Collaboration Foundation
    Inventors: Jin-eun Kim, Q-han Park, Chang-won Lee, Yeon-sang Park, Young-geun Roh, Hwan-soo Suh, Jong-ho Choe
  • System and method for attaching soft tissue to an implant comprising a nanotextured surface
    Patent number: 9498218
    Abstract: One embodiment of the present invention is directed to compositions and methods for enhancing attachment of soft tissues to a metal prosthetic device. In one embodiment a construct is provided comprising a metal implant having a porous metal region, wherein the porous region exhibits a nano-textured surface, and a biocompatible polymer matrix coating the nano-textured surface. The polymer matrix coating comprises a naturally occurring extracellular matrix with biocompatible inorganic materials distributed within the matrix, or a biocompatible polymer and an osteo-inductive agent.
    Type: Grant
    Filed: January 22, 2015
    Date of Patent: November 22, 2016
    Assignees: Purdue Research Foundation, DePuy Synthes Products, Inc.
    Inventors: Perla Venu, Prasanna Malaviya, Thomas J. Webster
  • TIMP3 as VEGF inhibitor
    Patent number: 9498509
    Abstract: Polypeptides or proteins comprising tissue inhibitor of mettaloproteinases-3 (TIMP3) or variants of TIMP3 can be used to substantially inhibit vascular endothelial growth factor (VEGF) binding to VEGF receptor-2 (VEGFR2/KDR/Flk-1)) without substantially inhibiting VEGF binding to VEGF receptor 1 (VEGFR1/Flt-1).
    Type: Grant
    Filed: January 16, 2007
    Date of Patent: November 22, 2016
    Assignee: The Cleveland Clinic Foundation
    Inventor: Bela Anand-Apte
  • Die for reducing springback and process thereof
    Patent number: 9498812
    Abstract: A sheet metal forming device and a process for reducing springback during forming of sheet metal. The sheet metal forming device includes a die tool that has a corner and a roller that at least partially forms the corner. The roller rotates relative to the die tool during and/or after forming of a piece of sheet metal around the corner. The rotation of the roller can be either a rotation that freely occurs during the forming process or rotation that is forcibly imposed on the roller during and/or after the forming process.
    Type: Grant
    Filed: August 22, 2014
    Date of Patent: November 22, 2016
    Assignee: The Penn State Research Foundation
    Inventor: Chetan P. Nikhare
  • Collimator for redirecting compton scattered radiation in stereotactic radiosurgery
    Patent number: 9498646
    Abstract: A collimator assembly for use with radiation therapy systems, in particular stereotactic radiosurgery (“SRS”) systems, is provided. In general, the collimator assembly includes a collimator in which a plurality of concentric, conical slits is formed. Each conical slit is oriented along a different slit angle, such that radiation impinging on the top surface of the collimator is redirected along each conical slit towards a common target isocenter located at a distance away from the bottom surface of the collimator. The conical slits can be referred to as “Compton slits” because they are designed to increase the radiation output at the isocenter of the collimator by redirecting Compton scattered radiation towards the isocenter in the target region. The collimator assembly thus improves the efficiency of a radiation treatment system by utilizing Compton scattered radiation that would otherwise be lost.
    Type: Grant
    Filed: August 13, 2014
    Date of Patent: November 22, 2016
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Edward T. Bender, Andrew J. Shepard
  • Synchronization of ion generation with cycling of a discontinuous atmospheric interface
    Patent number: 9500623
    Abstract: The invention generally relates to methods and devices for synchronization of ion generation with cycling of a discontinuous atmospheric interface. In certain embodiments, the invention provides a system for analyzing a sample that includes a mass spectrometry probe that generates sample ions, a discontinuous atmospheric interface, and a mass analyzer, in which the system is configured such that ion formation is synchronized with cycling of the discontinuous atmospheric interface.
    Type: Grant
    Filed: October 14, 2013
    Date of Patent: November 22, 2016
    Assignee: Purdue Research Foundation
    Inventors: Robert Graham Cooks, Jason Duncan, Guangming Huang, Guangtao Li, Xin Yan, Ewa Sokol, Xin Li
  • Integrated circuit providing fault prediction
    Patent number: 9500705
    Abstract: The prediction of hardware failure is obtained by operating two redundant circuit modules while one circuit module is artificially aged. The output of the two circuit modules is compared and a discrepancy between outputs indicates a projected failure of the aged modules. Aging may be accomplished by one or a combination of lowering operating voltages and re-phasing a sampling clock to reduce slack time both of which provide increased sensitivity to gate delay.
    Type: Grant
    Filed: August 28, 2013
    Date of Patent: November 22, 2016
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Raghuraman Balasubramanian, Karthikeyan Sankaralingam
  • Sensing circuit for resistive memory cells
    Patent number: 9502091
    Abstract: A sensing system may include a sense amplifier, a sensing circuit configured to sense a current difference, a data cell selectively coupled to the sensing circuit, a first reference cell selectively coupled to the sensing circuit, and a second reference cell selectively coupled to the sensing circuit. The resistance of the first reference cell and the second reference cell are different.
    Type: Grant
    Filed: September 2, 2015
    Date of Patent: November 22, 2016
    Assignees: QUALCOMM Incorporated, Industry-Academic Cooperation Foundation, Yonsei University
    Inventors: Seong-Ook Jung, Taehui Na, Byung Kyu Song, Jung Pill Kim, Seung Hyuk Kang
  • Sample dispenser including an internal standard and methods of use thereof
    Patent number: 9500572
    Abstract: The invention generally relates to a sample dispenser including an internal standard and methods of use thereof. In certain embodiments, the invention provides a fluid dispenser that includes a fluid chamber. A portion of an inner wall of the chamber includes an internal standard. The chamber is configured such that fluid introduced to the chamber must interact with the portion of the chamber wall that includes the internal standard prior to flowing through an outlet of the chamber. The dispenser additionally includes a member coupled to the chamber such that it can control movement of fluid within the chamber.
    Type: Grant
    Filed: March 4, 2013
    Date of Patent: November 22, 2016
    Assignee: Purdue Research Foundation
    Inventors: Zheng Ouyang, He Wang, Nicholas E. Manicke, Robert Graham Cooks, Qian Yang, Jiangjiang Liu
  • Tyrosine kinase biosensors and methods of use
    Patent number: 9499854
    Abstract: The claims describe a process for designing and validating peptide-based substrates for a specified kinase. The process uses a rational approach to design peptides with a specific amino acid that is phosphorylated by a target tyrosine kinase, and upon phosphorylation shows an increased affinity for a lanthanide ion that results in an enhanced fluorescent signal. The process uses kinase specific input data sets, encodes the input into positional scoring matrices, analyses the positional scoring matrices in order to generate a candidate list of peptide sequences, compares the peptide sequences in the candidate list, substitutes residues at non-selective positions in selections from the candidate list with terbium binding residues, and then screens the substituted selections with different kinases in vitro.
    Type: Grant
    Filed: February 7, 2013
    Date of Patent: November 22, 2016
    Assignee: Purdue Research Foundation
    Inventors: Laurie Louise Parker, Andrew M. Lipchik, Scott Charles Bolton
  • Grouping method and device for enhancing redundancy removing performance for storage unit
    Patent number: 9501239
    Abstract: The present invention relates to a grouping method and device for enhancing redundancy removing performance for a storage unit such as a hard disk, a solid state disk (SSD), etc. The grouping method for enhancing performance of a redundancy removing technology may include: extracting samples from data that is stored in a buffer of a memory and is standing by to be processed; performing remaining calculations on the extracted samples; and grouping samples by connecting them to a bucket corresponding to a resultant value of the remaining calculations.
    Type: Grant
    Filed: December 10, 2012
    Date of Patent: November 22, 2016
    Assignee: Industry-University Cooperation Foundation Hanyang University
    Inventors: Soo Yong Kang, You Jip Won, Jae Hyuk Cha, Jong Moo Choi, Sung Roh Yoon, Jong Hwa Kim, Ik Joon Son, Sang Yup Lee
  • Compounds and methods for treating HIV
    Patent number: 9499558
    Abstract: Inhibitors of HIV-1 protease and compositions containing them are described. Use of the inhibitors and compositions containing them to treat HIV, AIDS, and AIDS-related diseases is described.
    Type: Grant
    Filed: April 21, 2015
    Date of Patent: November 22, 2016
    Assignee: Purdue Research Foundation
    Inventors: Arun K. Ghosh, Bruno D. Chapsal, Hiroaki Mitsuya, Cuthbert D Martyr
  • Dishwasher using oscillatory flow generated from thermoacoustic effect
    Patent number: 9498101
    Abstract: Disclosed herein is a dishwasher using oscillatory flow generated from thermoacoustic effect. The dishwasher is configured such that thermoacoustic waves having high amplitude are generated from solar energy rather than electric energy, wherein the thermoacoustic waves make oscillating waves be directly transmitted to an air column and a water column formed in a closed end of a dishwashing pipeline. In this way, high-quality energy can be directly applied to washing water, whereby energy loss can be minimized, and the washing efficiency can be markedly increased.
    Type: Grant
    Filed: August 28, 2014
    Date of Patent: November 22, 2016
    Assignee: Jeju National University Industry-Academic Cooperation Foundation
    Inventors: Wongee Chun, Seungjin Oh, Namjin Kim, Youncheol Park, Yeongmin Kim, Kuan Chen
  • Method for differentiating stem cells into neurons
    Patent number: 9499787
    Abstract: The present invention relates to a method for differentiating stem cells into neurons, and is characterized in that stem cells are treated with a culture additive comprising lipoic acid, albumin, hydrocortisone, and insulin after culturing for differentiation into neurons. Since the neurons produced according to the method for producing neurons of the present invention express nestin, neuroD1, neuron-specific enolase (NSE), neurofilament (NF), tau, microtubule-associated protein 2 (MAP2), and doublecortin (DCX), just as normal mature neurons do, the neurons of the present invention can be effectively used in various therapeutic agents for neurons and as cell origins for an in vitro study system.
    Type: Grant
    Filed: February 5, 2013
    Date of Patent: November 22, 2016
    Assignee: Dongguk University Industry—Academic Cooperation Foundation
    Inventors: Jung Keug Park, Hee Hoon Yoon, Soo Yeon Kim, Young Kwon Seo
  • Method and apparatus for inspecting an object employing machine vision
    Patent number: 9500475
    Abstract: A machine vision system including a digital camera can be employed to inspect an object in a field of view. This includes projecting digitally-generated light patterns including first and second boundary patterns and first and second spatial patterns onto the object in the field of view. Images associated with the projected light patterns including the object are captured. Spatial cells are found in the field of view by matching codes in the first and second spatial patterns to boundaries determined based upon one of the first and second boundary patterns. The spatial cells are found in the field of view by matching codes in the spatial patterns to boundaries determined based upon the boundary patterns. The spatial cells are decoded and matched to the boundaries. Three-dimensional (3D) point cloud data of the object is generated based upon the decoded spatial cells matched to the boundaries.
    Type: Grant
    Filed: January 8, 2015
    Date of Patent: November 22, 2016
    Assignees: GM Global Technology Operations LLC, SungyKyunKwan University Foundation for Corporate Collaboration
    Inventors: Sukhan Lee, Quang-Lam Bui, Jianying Shi
  • Systems and methods for estimating the geographic location at which image data was captured
    Patent number: 9501699
    Abstract: In some embodiments, a system and method for estimating the geographical location at which image data was captured with a camera identifies matching feature points between the captured images, estimates a pose of the camera during the image capture from the feature points, performs geometric reconstruction of a scene in the images using the estimated pose of the camera to obtain a reconstructed scene, and compares the reconstructed scene to overhead images of known geographical origin to identify potential matches.
    Type: Grant
    Filed: May 12, 2012
    Date of Patent: November 22, 2016
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Hakjae Kim, Warren Dixon
  • Stabilization of an injection locked harmonically mode-locked laser via polarization spectroscopy for frequency comb generation
    Patent number: 9502856
    Abstract: Stabilization of an injection locked optical frequency comb is achieved through polarization spectroscopy of an active laser cavity, eliminating optical PM sidebands inherent in previous stabilization methods. Optical SNR of 35 dB is achieved. A monolithic AlInGaAs quantum well Fabry-Prot laser injection locked to a passively mode-locked monolithic laser is presented here. The FP laser cavity can be used as a true linear interferometric intensity modulator for pulsed light.
    Type: Grant
    Filed: April 11, 2013
    Date of Patent: November 22, 2016
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventors: Peter J. Delfyett, Charles Williams, Edris Sarailou
  • Method of treating lung diseases using cells separated or proliferated from umbilical cord blood
    Patent number: 9498497
    Abstract: There is provided a method of treating lung diseases including administering cells separated or proliferated from umbilical cord blood to a patient suffering from such diseases.
    Type: Grant
    Filed: August 1, 2008
    Date of Patent: November 22, 2016
    Assignees: MEDIPOST Co., Ltd., Samsung Life Public Welfare Foundation
    Inventors: Yun Sil Chang, Won Soon Park, Yoon-Sun Yang
  • Apparatus and method for targeting a body tissue
    Patent number: 9498584
    Abstract: An apparatus for targeting a desired target site on a body tissue comprising a wall of a first body cavity of a patient includes a target catheter. The framing member has a longitudinal framing member core defining a central framing member axis. At least one target point is carried by the framing member and is adapted for placement adjacent the desired target site. The framing member comprises a plurality of longitudinally extending multi-segment framing strands.
    Type: Grant
    Filed: October 22, 2013
    Date of Patent: November 22, 2016
    Assignee: The Cleveland Clinic Foundation
    Inventors: Samir Kapadia, Marwane Berrada, Cesar Fuentes-Ortega, Daniel Wing Fai Mok
  • Serine protease molecules and therapies
    Patent number: 9499807
    Abstract: Cell-targeted serine protease constructs are provided. Such constructs can be used in methods for targeted cell killing such as for treatment cell of proliferative diseases (e.g., cancer). In some aspects, recombinant serine proteases, such as Granzyme B polypeptides, are provided that exhibit improved stability and cell toxicity. Methods and compositions for treating lapatinib or trastuzumab-resistant cancers are also provided.
    Type: Grant
    Filed: July 2, 2014
    Date of Patent: November 22, 2016
    Assignee: Research Development Foundation
    Inventors: Michael G. Rosenblum, Khalid Amanali Mohamedali, Lawrence H. Cheung