Patents Assigned to Fraunhofer
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Publication number: 20250122578Abstract: Disclosed is a method for identifying a cfDNA derived biomarker for a physiological condition, disease or disorder comprising: a) isolating cfDNA from a sample of a subject known to be in the physiological condition or suffer from the disease or disorder; b) selecting short double-stranded cfDNA fragments; c) determining the nucleic acid sequences of said short double-stranded cfDNA fragments; d) comparing the nucleic acid sequences of said short double-stranded cfDNA fragments to a reference; and; e) based on said comparison in step d) identifying at least one cfDNA derived biomarker associated with the physiological condition, disease or disorder; a method for assessing a physiological condition, disease or disorder; a method for determining efficacy of treating a physiological condition, disease or disorder; use of a cfDNA derived biomarker in a sample for assessing a disease or disorder in a subject; and a device for detecting a cfDNA derived biomarker in a sample.Type: ApplicationFiled: October 10, 2024Publication date: April 17, 2025Applicant: Fraunhofer-Gesellschaft zur Forderung der angewandten Forschung e.V.Inventors: Christina HARTWIG, Jan MULLER, Kai SOHN, Mirko SONNTAG
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Patent number: 12274971Abstract: Apparatuses and methods are provided for applying accelerated electrons to a gaseous medium by means of an electron beam generator, which has at least one cathode for emitting electrons and at least one electron exit window, wherein a) the at least one cathode is annular and the at least one electron exit window is in the form of an annular first hollow cylinder, the annular electron exit window in the form of the first hollow cylinder forms an inner wall of an annular housing of the electron beam generator, wherein the electrons emitted by the cathode are accelerated to the ring axis of the annular housing; b) an annular second hollow cylinder is arranged within the electron exit window in the form of the first hollow cylinder and delimits an annular space between the first hollow cylinder and the second hollow cylinder; c) a cooling gas is fed through the annular space between the first hollow cylinder and the second hollow cylinder; and d) the gaseous medium to which accelerated electrons are to be appliedType: GrantFiled: December 14, 2020Date of Patent: April 15, 2025Assignee: Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.Inventors: Gösta Mattausch, André Weidauer, Ralf Blüthner, Jörg Kubusch, Frank-Holm Rögner, Volker Kirchhoff, Rainer Labitzke, Burkhard Zimmermann
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Patent number: 12278960Abstract: Block-based coding of a picture is done by providing an intra-prediction coding concept according to which a certain block of the picture is intra-prediction coded using a certain intra-coding mode by partitioning the predetermined block into partitions which are, for reconstruction purposes, sequentially subject to spatial prediction using the intra-prediction coding mode signaled for the certain block followed by correcting the thus obtained predictor using a prediction residual so that for preceding partitions a reconstruction of the samples is available to the decoder at the time of processing the next, then current, partition.Type: GrantFiled: December 6, 2023Date of Patent: April 15, 2025Assignee: Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.Inventors: Santiago De Luxán Hernández, Philipp Merkle, Heiko Schwarz, Detlev Marpe, Thomas Wiegand
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Patent number: 12279151Abstract: A wireless communication system includes one or more base stations, and one or more user devices, UEs. When running a certain application, the UE is to communicate over a session, like a PDU session, the session having associated therewith a current Quality of Service, QoS, profile, the current QoS profile selected form a plurality of different QoS profiles associated with the session. In case of a certain event, the wireless communication system is to replace the current QoS profile for the session by a new QoS profile for the session, the new QoS profile selected from a subset or all of the plurality of different QoS profiles associated with the session and/or one or more QoS profiles not yet associated with the session.Type: GrantFiled: March 18, 2022Date of Patent: April 15, 2025Assignee: Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.Inventors: Roya Ebrahim Rezagah, Thomas Fehrenbach, Cornelius Hellge, Thomas Wirth, Thomas Schierl, Thomas Haustein, Sarun Selvanesan
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Patent number: 12279183Abstract: A wireless communication system includes a plurality of user devices, UEs, and at least one logical group defined in accordance with one or more logical group criteria. The logical group includes a plurality of member UEs to be connected via sidelink for sidelink communication with each other, and all member UEs of the logical group have assigned the same destination identification, ID, the destination ID being unique for the logical group.Type: GrantFiled: June 2, 2024Date of Patent: April 15, 2025Assignee: Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.Inventors: Sarun Selvanesan, Thomas Fehrenbach, Roya Ebrahim Rezagah, Cornelius Hellge, Thomas Wirth, Thomas Schierl, Robin Thomas, Baris Göktepe, Eiko Seidel
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Patent number: 12277941Abstract: There are disclosed several examples of encoding and decoding technique. In particular, an audio synthesizer for generating a synthesis signal from a downmix signal, includes: an input interface for receiving the downmix signal, the downmix signal having a number of downmix channels and side information, the side information including channel level and correlation information of an original signal, the original signal having a number of original channels; and a synthesis processor for generating, according to at least one mixing rule, the synthesis signal using: channel level and correlation information of the original signal; and covariance information associated with the downmix signal.Type: GrantFiled: December 14, 2021Date of Patent: April 15, 2025Assignee: Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.Inventors: Alexandre Bouthéon, Guillaume Fuchs, Markus Multrus, Fabian Küch, Oliver Thiergart, Stefan Bayer, Sascha Disch, Jürgen Herre
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Patent number: 12273805Abstract: A wireless communication system, including: a plurality of time variant transmission points for communicating with a user device, UE, wherein the UE is in a tracking region, wherein the UE is configured to receive and store a list including identifiers, IDs, of time variant transmission points for the tracking region, and wherein the list includes IDs of time variant transmission points which are available or visible for the UE in the one tracking region at different times or time periods.Type: GrantFiled: October 27, 2021Date of Patent: April 8, 2025Assignee: Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.Inventors: Thi Uyen Ly Dang, Thomas Heyn, Alexander Hofmann, Elke Roth-Mandutz, Thomas Fehrenbach, Leszek Raschkowski
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Patent number: 12272365Abstract: An apparatus processing an encoded signal to acquire first and second frames comprising spectral values and an aliasing portion; applying a transform to the first frame using a first window function to acquire a first block of samples, applying another transform to a first portion of the second frame using a second window function, and applying another one or more transforms to a second portion of the second frame using one or more third window functions to acquire a second block of samples; and post-processing the second block of samples using a folding-out operation to acquire a post-processed second block of samples comprising a portion of the second block of samples overlapping with the first block of samples in a multi-overlap region, windowing the post-processed second block of samples using an auxiliary window function, and overlap-adding a windowed post-processed second block of samples and the first block of samples.Type: GrantFiled: February 17, 2023Date of Patent: April 8, 2025Assignee: Fraunhofer-Gesellschaft zur Foerderung der angewandten Forschung e.V.Inventors: Christian Helmrich, Jérémie Lecomte, Goran Markovic, Markus Schnell, Bernd Edler, Stefan Reuschl
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Patent number: 12272493Abstract: A method for producing a spiral-shaped body, in particular an electric coil, made of an electrically conductive material. First, the material is wound about a mandrel in a casting mold in order to form a coil with a plurality of windings, and pressure is then exerted onto the coil in the axial direction of the coil. The pressure leads to a deformation and compression of the cross-section of the individual windings in the axial direction of the coil. By compressing the coil, an optimal use of space is achieved with an electric coil, for example for an electric machine.Type: GrantFiled: February 14, 2020Date of Patent: April 8, 2025Assignee: Fraunhofer-Gesellschaft zur Förderung der Angewandten Forschung E.V.Inventors: Matthias Busse, Franz-Josef Wöstmann
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Patent number: 12273519Abstract: Embodiments of the present invention provide an encoder including a quantization stage, an entropy encoder, a residual quantization stage and a coded signal former. The quantization stage is configured to quantize an input signal using a dead zone in order to obtain a plurality of quantized values. The entropy encoder is configured to encode the plurality of quantized values using an entropy encoding scheme in order to obtain a plurality of entropy encoded values. The residual quantization stage is configured to quantize a residual signal caused by the quantization stage, wherein the residual quantization stage is configured to determine at least one quantized residual value in dependence on the dead zone of the quantization stage. The coded signal former is configured to form a coded signal from the plurality of entropy encoded values and the at least one quantized residual value.Type: GrantFiled: July 8, 2020Date of Patent: April 8, 2025Assignee: Fraunhofer-Gesellschaft zur Foerderung der angewandten Forschung e.V.Inventors: Guillaume Fuchs, Benjamin Schubert, Grzegorz Pietrzyk, Markus Multrus, Bernhard Grill
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Patent number: 12273993Abstract: The invention relates to a carrier arrangement (100; 500; 600; 700; 800; 900; 1000), and a method for producing a carrier arrangement. The method comprises: producing a layer (130; 530; 630; 730; 830; 930; 1030) on a surface (120; 520; 620; 720; 820; 920; 1020) of a carrier (110; 510; 610; 710; 810; 910; 1010), the layer comprising a first region (131; 531; 631; 731; 831; 931; 1031) and a second region (132; 532; 632; 732; 832; 932; 1032) connected to the first region, the first region covering a first surface region (121; 521; 621; 721; 821; 921; 1021) of the carrier and the second region covering a second surface region (122; 722; 922) of the carrier, detaching the second region of the layer from the carrier, the first region of the layer remaining on the first surface region of the carrier and not being separated from the second region, the layer being flexible in the detached second region.Type: GrantFiled: March 13, 2024Date of Patent: April 8, 2025Assignee: Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.Inventors: Mathias Bottcher, Frank Windrich, Kai Zoschke, M. Jürgen Wolf
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Patent number: 12273766Abstract: The embodiments herein relate to a method performed by a UE (800) capable for sidelink communications, for congestion control in a wireless telecommunications network, wherein the UE is allocated one or more resource pools, the method comprising: performing (701) CBR/CR measurements on said at least one resource pool to generate CBR/CR value(s); wherein the measurements are performed over a sensing window which is either pre-configured or adapted based on the QoS of at least one data packet or at least one service, and selecting (702) a resource pool or at least one resource within the resource pool based on a CBR/value and QoS requirements of the data packet or the service for transmission.Type: GrantFiled: December 10, 2019Date of Patent: April 8, 2025Assignee: Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.Inventors: Khaled Hassan, Shubhangi Bhadauria, Elke Roth-Mandutz, Martin Leyh
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Patent number: 12273737Abstract: A wireless communication system including: at least a first terrestrial or non-terrestrial base station, the first base station configured to generate one or more beams for covering at least a first beam coverage area; wherein the first base station is configured to broadcast at least to the first beam coverage area a list of tracking area IDs including a first tracking area ID belonging to a first tracking region and a second tracking area ID belonging to a second tracking region.Type: GrantFiled: April 27, 2021Date of Patent: April 8, 2025Assignee: Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.Inventors: Thi Uyen Ly Dang, Thomas Heyn, Alexander Hofmann, Leszek Raschkowski, Thomas Fehrenbach, Stephan Jaeckel
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Patent number: 12266372Abstract: There are disclosed several examples of encoding and decoding technique. In particular, an audio synthesizer for generating a synthesis signal from a downmix signal, includes: an input interface for receiving the downmix signal, the downmix signal having a number of downmix channels and side information, the side information including channel level and correlation information of an original signal, the original signal having a number of original channels; and a synthesis processor for generating, according to at least one mixing rule, the synthesis signal using: channel level and correlation information of the original signal; and covariance information associated with the downmix signal.Type: GrantFiled: December 14, 2021Date of Patent: April 1, 2025Assignee: Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.Inventors: Alexandre Bouthéon, Guillaume Fuchs, Markus Multrus, Fabian Küch, Oliver Thiergart, Stefan Bayer, Sascha Disch, Jürgen Herre
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Patent number: 12266375Abstract: Described are an encoder for coding speech-like content and/or general audio content, wherein the encoder is configured to embed, at least in some frames, parameters in a bitstream, which parameters enhance a concealment in case an original frame is lost, corrupted or delayed, and a decoder for decoding speech-like content and/or general audio content, wherein the decoder is configured to use parameters which are sent later in time to enhance a concealment in case an original frame is lost, corrupted or delayed, as well as a method for encoding and a method for decoding.Type: GrantFiled: July 5, 2023Date of Patent: April 1, 2025Assignee: Fraunhofer-Gesellschaft zur Foerderung der angewandten Forschung e.V.Inventors: Jérémie Lecomte, Benjamin Schubert, Michael Schnabel, Martin Dietz
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Patent number: 12266371Abstract: A multi-channel audio encoder for providing an encoded audio representation on the basis of an input audio representation is provided. The multi-channel audio encoder is configured to switch between a parametric multi-channel encoding of a plurality of channels and an individual encoding of a plurality of channels in dependence on characteristics of the input audio representation.Type: GrantFiled: October 1, 2021Date of Patent: April 1, 2025Assignee: Fraunhofer-Gesellschaft zur Foerderung der angewandten Forschung e.V.Inventors: Emmanuel Ravelli, Eleni Fotopoulou, Markus Multrus, Guillaume Fuchs
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Patent number: 12267197Abstract: An apparatus for a wireless communication system is to transmit a reference signal on a common set of resource elements, REs, the common set of REs used by one or more further apparatuses in the wireless communication system to transmit the reference signal so that the reference signals of the apparatus and of the one or more further apparatuses use the same REs. The reference signal is transmit using OFDM symbols and the same sequence having a zero auto correlation property is applied to each OFDM symbol. A phase correction is applied to an OFDM symbol before transmission, wherein a correction factor of the phase correction depends on a comb factor and a comb offset of the OFDM symbol and is independent of the resource element.Type: GrantFiled: April 28, 2022Date of Patent: April 1, 2025Assignee: Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.Inventors: Mohammad Alawieh, Ernst Eberlein, Marcus Großmann, Birendra Ghimire
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Publication number: 20250101724Abstract: An apparatus includes a flow range configured to let a fluid having a flow characteristic flow. The apparatus includes actuator means configured to change the flow characteristic of the flow range and further includes acoustic sensor means configured to receive an acoustic signal and to output a sensor signal based on the acoustic signal. The apparatus includes an analysis means configured to analyze the sensor signal to obtain an analysis result. The apparatus is configured to control the actuator means based on the analysis result for changing the flow characteristic.Type: ApplicationFiled: December 6, 2024Publication date: March 27, 2025Applicant: Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.Inventors: Jens-Ekkehart APPELL, Thomas SPORER
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Publication number: 20250102381Abstract: A measuring device is provided having at least one substrate, which contains or consists of a polymer or a glass, at least one optical waveguide being written in the substrate, in which at least one Bragg grating with a predeterminable grating constant is arranged, wherein the measuring device further includes an evaluation device, which is configured to determine a deformation of the substrate and/or a force acting on the substrate from a change in the grating constant and/or a change in the refractive index of the Bragg grating.Type: ApplicationFiled: September 16, 2024Publication date: March 27, 2025Applicant: Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.Inventors: Wolfgang Schade, Martin Angelmahr, Jannis Koch
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Patent number: 12262035Abstract: A video data stream is rendered reducible in a manner so that the reduction leads to a restriction of pictures of the reduced video data stream to merely a predetermined subarea of the pictures of the original video data stream and in a manner so that transcoding, such as re-quantization, may be avoided and a conformance of the reduced video data stream relative to the codec underlying the original video data stream be maintained. This is achieved by providing the video data stream with information including an indication of the predetermined subarea and replacement indices for redirecting the indices included by the payload portion so as to refer to, and/or replacement parameters for adjusting the first set of coding parameter settings so as to result in, a second set of coding parameter settings.Type: GrantFiled: May 15, 2024Date of Patent: March 25, 2025Assignee: Fraunhofer-Gesellschaft zur Foerderung der angewandten Forschung e.V.Inventors: Robert Skupin, Yago Sánchez De La Fuente, Thomas Schierl, Cornelius Hellge, Karsten Grueneberg, Thomas Wiegand