Patents Assigned to Fukuoka University
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Patent number: 9918738Abstract: [Problem] Provided are: an ultrasound-guided puncture assist device that is capable of preventing occurrence of operational mistakes or the like when a nerve block or vascular puncture is performed under ultrasonography, an ultrasound-guided puncture method using the ultrasound-guided puncture assist device, and the like. [Solution] An ultrasound-guided puncture assist device with an object of preventing narrowing or the like of a puncture target site for a nerve block or vascular puncture under ultrasonography to thereby assist the puncture by comprising a pulling mechanism for pulling the surface of the puncture target site, such as skin. The use of the ultrasound-guided puncture assist device of the invention can increase the width of the target site tissue where a nerve block or vascular puncture is performed, and thus occurrence of mispuncture is preventable.Type: GrantFiled: March 27, 2014Date of Patent: March 20, 2018Assignee: Fukuoka UniversityInventors: Isao Haraga, Kazuo Higa, Keiichi Nitahara
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Patent number: 9910052Abstract: Markers useful in diagnosing disseminated intravascular coagulation (DIC) or infectious DIC are provided. In a method for detecting DIC of the present invention, sCD14-ST in a sample is measured. In a method of detecting infectious DIC of the present invention, sCD14-ST and a coagulation-related marker in a sample are measured.Type: GrantFiled: April 26, 2013Date of Patent: March 6, 2018Assignees: LSI MEDIENCE CORPORATION, FUKUOKA UNIVERSITYInventor: Hiroyasu Ishikura
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Patent number: 9769125Abstract: An information administration system configured of: a component information management apparatus (4) including a component information storing unit (41) storing component information after sectionalizing the component information into public information and non-public information, and also sectionalizing the non-public information into information for designing and information for manufacturing, and an encryption processing unit (42) encrypting the non-public information; a designing information management apparatus (2) including a first component information receiving unit (24) receiving the component information, a first decryption unit (25) decrypting non-public component information for designing, and a designing information storing unit (22) storing designing information that is designed by adding the received component information thereto; and a manufacturing apparatus (3) including a second decryption unit (33) decrypting the received non-public component information for manufacturing, and a drive contType: GrantFiled: January 23, 2015Date of Patent: September 19, 2017Assignees: ZUKEN INC., FUJI MACHINE MFG CO LTD, FUKUOKA UNIVERSITYInventors: Hajime Tomokage, Hidemichi Kawase, Hiroshi Matsuoka, Hirohiko Matsuzawa, Kazuhiro Kusunoki, Hiroshi Yamazaki
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Patent number: 9764029Abstract: Provided are a tumor proliferation inhibitor and a method for inhibiting tumor proliferation both of which can be applied to a minimally invasive cancer treatment using low-intensity pulsed ultrasound. The present invention provides a tumor proliferation inhibitor containing an ultrasound-sensitive substance and an acoustic cavitation phenomenon-enhancing substance, and provides a method for inhibiting tumor proliferation that can exhibit a tumor proliferation-inhibitory effect using the tumor proliferation inhibitor in combination with low-intensity pulsed ultrasound of a degree that is used in ultrasound diagnosis, and that can be applied to a minimally invasive cancer treatment using low-intensity pulsed ultrasound.Type: GrantFiled: February 21, 2014Date of Patent: September 19, 2017Assignee: FUKUOKA UNIVERSITYInventors: Hirotomo Shibaguchi, Hirofumi Tsuru
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Patent number: 9452036Abstract: A dental ultrasonic drug delivery system capable of accurately cleaning the inside of root canals and killing bacteria in dentin tubules is provided. The dental ultrasonic drug delivery system delivers a drug to a target using an ultrasonic delivery device 800 . The drug is delivered in a mixed state with nanobubbles. A dental therapeutic probe for applying ultrasound is attached to the ultrasonic delivery device 800 . The dental therapeutic probe is selected from: (1) a root canal insertion probe 100 which is configured to be inserted into a root canal and causes ultrasound to propagate in the root canal; (2) a dental caries therapeutic probe which causes ultrasound to propagate in a dental caries portion; (3) a periodontal disease therapeutic probe which applies ultrasound to a periodontal disease portion; and (4) a hyperesthesia therapeutic probe which applies ultrasound to hyperesthesia portion.Type: GrantFiled: December 16, 2010Date of Patent: September 27, 2016Assignees: National Center for Geriatrics and Gerontology, Fukuoka UniversityInventors: Misako Nakashima, Katsuro Tachibana
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Patent number: 9330496Abstract: There is provided a 3-dimensional coordinate specifying device which can accurately specify a set or sets of optional coordinates in a 3-dimensional space by a simple manipulation. The 3-dimensional coordinate specifying device includes a standard plane setting section 22 for setting an optional standard flat plane 31 in a 3-dimensional space, a standard point determining section 23 for determining values of coordinates of an optional point on the set standard flat plane 31, a light beam emitting section 25 for emitting an imaginary light beam 33 at an optional angle from the determined standard point 32, a point specifying section 26 for specifying an optional point on the emitted imaginary light beam, and a coordinate calculating section 27 for calculating 3-dimensional coordinates of the specified point.Type: GrantFiled: December 22, 2010Date of Patent: May 3, 2016Assignee: Fukuoka UniversityInventors: Hajime Tomokage, Hidemichi Kawase, Osamu Horiuchi
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Patent number: 9238814Abstract: The hammerhead ribozyme according to the present invention produces a hammerhead ribozyme—target RNA construct by base-pairing with an edited target RNA, and an editing recognition site of the hammerhead ribozyme cleaves the modification site by forming a base pair with the target RNA modification site. The cleavage of the modification site is expected to be applicable to the research and development of new drugs that can be used to prevent or treat diseases caused by the edited target RNA.Type: GrantFiled: May 19, 2012Date of Patent: January 19, 2016Assignee: Fukuoka UniversityInventors: Masatora Fukuda, Masanobu Deshimaru, Kei Kurihara
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Patent number: 9212333Abstract: A dispersant of the present invention is used after being added to a dispersant obtained by dispersing fine particles of a crystalline polymer as a dispersed particle and is characterized by containing a copolymer of a first monomer and a second monomer, the first monomer being a monomer that can be crystallized as a polymer having the molecular structure identical to that of the dispersed particle.Type: GrantFiled: November 8, 2011Date of Patent: December 15, 2015Assignee: Fukuoka UniversityInventors: Satoshi Ichikawa, Kazuhiro Oda, Shigeru Yao
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Patent number: 9206415Abstract: Disclosed herein is a method for simply inducing an anti-apoptotic effect and/or an anti-necrotic effect in a living cell with good control without administering any drug. The method includes applying an alternating-current voltage to the living cell so that an electric current of 25 ?A or higher but 75 ?A or lower flows to induce an anti-apoptotic effect and/or an anti-necrotic effect in the living cell. The living cell used may be a cultured cell. The alternating-current voltage may be applied to a stage member on which a container holding the living cell is placed.Type: GrantFiled: January 18, 2012Date of Patent: December 8, 2015Assignees: FUKUOKA UNIVERSITY, MAYATEC CO., LTD.Inventors: Shohta Kodama, Tomoyuki Godai
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Publication number: 20150191904Abstract: A composite structure includes a plate-like shear resistance member joined to a surface of a substrate in an erected manner and a concrete-based member formed on the surface of the substrate. The plate-like shear resistance member is embedded in the concrete-based member, and a through hole and a projecting rim portion projecting outside of at least one surface of the plate-like shear resistance member from an inner periphery of the through hole are provided on the plate-like shear resistance member.Type: ApplicationFiled: July 3, 2013Publication date: July 9, 2015Applicant: Fukuoka UniversityInventors: Teruhisa Tanaka, Junichi Sakai
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Publication number: 20140287000Abstract: Provided are a tumor proliferation inhibitor and a method for inhibiting tumor proliferation both of which can be applied to a minimally invasive cancer treatment using low-intensity pulsed ultrasound. The present invention provides a tumor proliferation inhibitor containing an ultrasound-sensitive substance and an acoustic cavitation phenomenon-enhancing substance, and provides a method for inhibiting tumor proliferation that can exhibit a tumor proliferation-inhibitory effect using the tumor proliferation inhibitor in combination with low-intensity pulsed ultrasound of a degree that is used in ultrasound diagnosis, and that can be applied to a minimally invasive cancer treatment using low-intensity pulsed ultrasound.Type: ApplicationFiled: February 21, 2014Publication date: September 25, 2014Applicant: FUKUOKA UNIVERSITYInventors: Hirotomo SHIBAGUCHI, Hirofumi TSURU
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Publication number: 20140256820Abstract: A medicinal agent or a pharmaceutical composition, each of which comprises a biguanides agent or a pharmaceutically acceptable salt thereof as an active ingredient, and which can potentiate blood-brain barrier functions including tight junction capability and transcellular transport capability of a brain capillary endothelial cell and therefore can treat blood-brain barrier dysfunction syndrome.Type: ApplicationFiled: December 12, 2011Publication date: September 11, 2014Applicant: FUKUOKA UNIVERSITYInventors: Fuyuko Takata, Shinya Dohgu, Yasufumi Kataoka, Junichi Matsumoto, Syuji Kaneshima
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Publication number: 20140228556Abstract: The hammerhead ribozyme according to the present invention produces a hammerhead ribozyme—target RNA construct by base-pairing with an edited target RNA, and an editing recognition site of the hammerhead ribozyme cleaves the modification site by forming a base pair with the target RNA modification site. The cleavage of the modification site is expected to be applicable to the research and development of new drugs that can be used to prevent or treat diseases caused by the edited target RNA.Type: ApplicationFiled: May 19, 2012Publication date: August 14, 2014Applicant: Fukuoka UniversityInventors: Masatora Fukuda, Masanobu Deshimaru, Kei Kurihara
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Publication number: 20140045053Abstract: A dispersant of the present invention is used after being added to a dispersant obtained by dispersing fine particles of a crystalline polymer as a dispersed particle and is characterized by containing a copolymer of a first monomer and a second monomer, the first monomer being a monomer that can be crystallized as a polymer having the molecular structure identical to that of the dispersed particle.Type: ApplicationFiled: November 8, 2011Publication date: February 13, 2014Applicant: Fukuoka UniversityInventors: Satoshi Ichikawa, Kazuhiro Oda, Shigeru Yao
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Publication number: 20130316429Abstract: Disclosed herein is a method for simply inducing an anti-apoptotic effect and/or an anti-necrotic effect in a living cell with good control without administering any drug. The method includes applying an alternating-current voltage to the living cell so that an electric current of 25 ?A or higher but 75 ?A or lower flows to induce an anti-apoptotic effect and/or an anti-necrotic effect in the living cell. The living cell used may be a cultured cell. The alternating-current voltage may be applied to a stage member on which a container holding the living cell is placed.Type: ApplicationFiled: January 18, 2012Publication date: November 28, 2013Applicants: MAYATEC CO., LTD., FUKUOKA UNIVERSITYInventors: Shohta Kodama, Tomoyuki Godal
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Patent number: 8580562Abstract: The inhibitory RNA for inhibiting the expression of ZFAT gene according to this invention is a siRNA comprising a sense RNA having a base sequence of contiguous 20 to 20 bases, preferably 23 to 27 bases, of ZFAT mRNA and an anti-sense RNA having a base sequence complementary to the base sequence of the sense RNA or a shRNA comprising a double-stranded RNA (dsRNA) with the sense RNA connected to the anti-sense RNA via a loop sequence. The inhibitory RNA for inhibiting the expression of ZFAT gene according to this invention decreases a rate of cell proliferation of cancer cells, etc., induces apoptosis of cells including cancer cells, or inhibits an immunoresponse by inhibiting the expression of the ZFAT gene. Therefore, the inhibitory RNA of this invention is useful for development of molecular target agents particularly for cancer cells or immunosuppressive agents.Type: GrantFiled: September 8, 2008Date of Patent: November 12, 2013Assignee: Fukuoka UniversityInventors: Senji Shirasawa, Takahiro Fujimoto, Toshiyuki Tsunoda, Keiko Doi, Midori Koyanagi
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Publication number: 20130231576Abstract: Provided are a somatic data-measuring apparatus that can easily and accurately measure the optimal exercise intensity for the subject being measured, and a somatic data measurement method.Type: ApplicationFiled: October 11, 2011Publication date: September 5, 2013Applicant: Fukuoka UniversityInventors: Hiroaki Tanaka, Takuro Matsuda
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Publication number: 20130211195Abstract: To develop a clinically useful composition and an endoscopic observation method that utilizes WOS properties. The composition for improving diagnostic performance, containing lipids as a component is characterized in that, by administering or loading said composition orally, by intubation or via an endoscope, the lipids are absorbed by gastric tumors, facilitating the detection of tumors and qualitative diagnoses by endoscope. Tumors are thus whitened by administering or loading this composition for improving diagnostic performance prior to endoscopic observation, making it easier to discover and qualitatively diagnose tumors by endoscopic observation.Type: ApplicationFiled: September 20, 2011Publication date: August 15, 2013Applicant: FUKUOKA UNIVERSITYInventor: Kenshi Yao
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Publication number: 20130129799Abstract: Provided are a tumor proliferation inhibitor and a method for inhibiting tumor proliferation both of which can be applied to a minimally invasive cancer treatment using low-intensity pulsed ultrasound. The present invention provides a tumor proliferation inhibitor containing an ultrasound-sensitive substance and an acoustic cavitation phenomenon-enhancing substance, and provides a method for inhibiting tumor proliferation that can exhibit a tumor proliferation-inhibitory effect using the tumor proliferation inhibitor in combination with low-intensity pulsed ultrasound of a degree that is used in ultrasound diagnosis, and that can be applied to a minimally invasive cancer treatment using low-intensity pulsed ultrasound.Type: ApplicationFiled: August 30, 2011Publication date: May 23, 2013Applicant: FUKUOKA UNIVERSITYInventors: Hirotomo Shibaguchi, Hirofumi Tsuru
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Publication number: 20130094490Abstract: A wireless communication apparatus has a first communication unit configured to perform at least one of transmission and reception by using a multicarrier signal constituted by a plurality of subcarriers shaped by a band-limited pulse waveform; and second communication unit configured to perform at least one of transmission and reception by using a signal having a different modulation format or modulation constant from said signal of said first communication unit. Said first communication unit configured to perform communication without using at least one of said plurality of subcarriers, and said second communication unit configured to perform communication using a band of said subcarrier not used by said first communication unit.Type: ApplicationFiled: August 20, 2012Publication date: April 18, 2013Applicants: TOYOTA INFOTECHNOLOGY CENTER CO., LTD., FUKUOKA UNIVERSITY, TOYOTA JIDOSHA KABUSHIKI KAISHAInventors: Makoto TAROMARU, Takahiko KISHI, Eiji NIWA