Patents Assigned to Galderma Research & Development
  • Biphenyl compound selective agonists of gamma RAR receptors
    Patent number: 8362082
    Abstract: Biphenyl compounds having the formula (I): are useful for preventing/treating pathologies linked to a deficiency of the activation of the RAR gamma receptor, e.g., for treating a pathology linked to a cell differentiation and/or proliferation disorder, for treating acne, for treating psoriasis.
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: January 29, 2013
    Assignee: Galderma Research & Development
    Inventors: Thibaud Biadatti, Etienne Thoreau
  • 4-(AZACYCLOALKYL)BENZENE-1,3-DIOL COMPOUNDS AS TYROSINASE INHIBITORS, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS
    Publication number: 20130023516
    Abstract: 4-(azacycloalkyl)benzene-1,3-diol compounds are described corresponding to general formula (I) below: Also described, are compositions including the same, processes for preparation thereof and uses thereof in pharmaceutical or cosmetic compositions to treat pigmentary disorders.
    Type: Application
    Filed: September 12, 2012
    Publication date: January 24, 2013
    Applicant: Galderma Research & Development
    Inventors: Jean-Guy BOITEAU, Karine Bouquet, Sandrine Talano, Corinne Millois Barbuis
  • Method for the synthesis of (Z)-3-[2-butoxy-3?-(3-heptyl-1-methyl-ureido)-biphenyl-4-yl]-2-methoxy-acrylic acid
    Patent number: 8357819
    Abstract: The invention relates to a process for the synthesis of (Z)-3-[2-butoxy-3?-(3-heptyl-1-methylureido)biphenyl-4-yl]-2-methoxyacrylic acid of formula (I): and also to the process for the synthesis of the reaction intermediates of general formula (XII), and to the said compounds when R2 is chosen from the methyl, trifluoromethyl, phenyl and 4-tolyl radicals:
    Type: Grant
    Filed: April 18, 2008
    Date of Patent: January 22, 2013
    Assignee: Galderma Research & Development
    Inventor: Jean-Guy Boiteau
  • COMBINATION OF ADRENERGIC RECEPTOR AGONIST ALPHA-1 OR ALPHA-2, PREFERABLY BRIMONIDINE WITH FILLERS, PREFERABLY HYALURONIC ACID
    Publication number: 20120295914
    Abstract: A combination of a quantity of adrenergic receptor agonist ?-1 or ?-2, and preferably product known as brimonidine, with fillers, and preferably with hyaluronic acid, for decreasing skin or cutaneous reactions is described.
    Type: Application
    Filed: May 28, 2010
    Publication date: November 22, 2012
    Applicant: Galderma Research & Development
    Inventors: Christophe Villard, Sylviane Villard
  • 4-(azacycloalkyl)benzene-1,3-diol compounds as tyrosinase inhibitors, process for the preparation thereof and use thereof in human medicine and in cosmetics
    Patent number: 8299259
    Abstract: 4-(azacycloalkyl)benzene-1,3-diol compounds are described corresponding to general formula (I) below: Also described, are compositions including the same, processes for preparation thereof and uses thereof in pharmaceutical or cosmetic compositions to treat pigmentary disorders.
    Type: Grant
    Filed: December 2, 2009
    Date of Patent: October 30, 2012
    Assignee: Galderma Research & Development
    Inventors: Jean-Guy Boiteau, Karine Bouquet, Sandrine Talano, Corinne Millois Barbuis
  • NOVEL LIGANDS THAT MODULATE RAR RECEPTORS
    Publication number: 20120258996
    Abstract: Novel ligand compounds having the general formula (I): and pharmaceutical/cosmetic compositions comprised thereof are useful in human and veterinary medicine or, alternatively, in cosmetics.
    Type: Application
    Filed: June 19, 2012
    Publication date: October 11, 2012
    Applicant: Galderma Research & Development
    Inventors: Thibaud BIADATTI, Laurence DUMAIS, Catherine SOULET, Sandrine TALANO, Sebastien DAVER
  • Phenylurea inhibitors of the SOAT-1 enzyme and pharmaceutical/cosmetic compositions comprised thereof
    Patent number: 8283378
    Abstract: Novel phenylurea compounds of formula (I): and cosmetic and pharmaceutical compositions containing same are useful for treating disorders of the sebaceous gland, e.g., acne, or have cosmetic applications.
    Type: Grant
    Filed: March 5, 2010
    Date of Patent: October 9, 2012
    Assignee: Galderma Research & Development
    Inventor: Thibaud Portal
  • Dermatological/cosmetic gels comprising at least one retinoid and/or retinoid salt and benzoyl peroxide
    Patent number: 8241649
    Abstract: Dermatological/cosmetic gel compositions suited for preventing or treating cell differentiation and/or proliferation and/or keratinization disorders, including preventing or treating common acne, comprise (i) at least one retinoid, (ii) dispersed benzoyl peroxide and (iii) at least one pH-independent gelling agent, formulated into (iv) a physiologically acceptable medium therefor.
    Type: Grant
    Filed: May 9, 2011
    Date of Patent: August 14, 2012
    Assignee: Galderma Research & Development
    Inventors: Sandrine Orsoni, Nathalie Willcox
  • Ligands that modulate RAR receptors
    Patent number: 8227507
    Abstract: Novel ligand compounds having the general formula (I): and pharmaceutical/cosmetic compositions comprised thereof are useful in human and veterinary medicine or, alternatively, in cosmetics.
    Type: Grant
    Filed: July 23, 2010
    Date of Patent: July 24, 2012
    Assignee: Galderma Research & Development
    Inventors: Thibaud Biadatti, Laurence Dumais, Catherine Soulet, Sandrine Talano, Sebastien Daver
  • Topical application of travoprost for combating hair loss
    Patent number: 8227514
    Abstract: Travoprost medicament compositions for non-daily topical application are useful for simulating or inducing the growth and/or decreasing the loss and/or increasing the density and/or reducing the heterogeneity in the diameter of human hair shafts/follicles, e.g., for the treatment of androgenic alopecia, such medicament compositions being at least twice applied over a time interval of greater than 24 hours.
    Type: Grant
    Filed: February 23, 2010
    Date of Patent: July 24, 2012
    Assignee: Galderma Research & Development
    Inventors: Sandrine Rethore, Carine Rosignoli, André Jomard, Johannes Voegel
  • INJECTABLE COMBINATION OF ADRENERGIC RECEPTOR AGONISTS WITH FILLERS, FOR DECREASING SKIN REACTIONS DUE TO INJECTION
    Publication number: 20120135937
    Abstract: The present invention concerns an injectable composition comprising a filler or a botulinum toxin and an adrenergic receptor agonist, and its use for diminishing, decreasing or avoiding skin reactions due to injection, specially redness, ecchymosis, bruising, bleeding, erythema, oedema, necrosis, ulceration, swelling and/or inflammation.
    Type: Application
    Filed: May 28, 2010
    Publication date: May 31, 2012
    Applicants: Galderma Research & Development, Symatese
    Inventors: Isabelle Bertholon, Florence Brunel, Benjamin Herbage, Christophe Villard, Sylviane Villard
  • COMBINATIONS OF ADAPALENE AND BENZOYL PEROXIDE FOR TREATING ACNE LESIONS
    Publication number: 20120136059
    Abstract: Adapalene or a pharmaceutically acceptable salt thereof formulated into a pharmaceutical composition is useful for reducing the number of acne lesions, via daily topical application, in combination or in association with benzoyl peroxide (BPO); such treatment may be via administration of a pharmaceutical composition combining adapalene and BPO or by a concomitant application of two pharmaceutical compositions, one containing adapalene and the other containing BPO.
    Type: Application
    Filed: November 30, 2011
    Publication date: May 31, 2012
    Applicant: Galderma Research & Development
    Inventors: Marie-line ABOU-CHACRA VERNET, Denis Gross, Christian Loesche, Michel Poncet
  • Ligand activators of the RAR receptors and pharmaceutical/cosmetic applications thereof
    Patent number: 8188106
    Abstract: Novel ligand compounds having the structural formula (I): in which: Ar is a radical selected from among the radicals of formulae (a)-(c) below: are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine, or, alternatively into cosmetic compositions.
    Type: Grant
    Filed: July 6, 2010
    Date of Patent: May 29, 2012
    Assignee: Galderma Research & Development
    Inventors: Thibaud Biadatti, Jean-Marie Arlabosse
  • INFRARED IMAGING OF CUTANEOUS MELANOMA
    Publication number: 20120123275
    Abstract: A process is described for identifying and classifying cutaneous melanoma of a lesion on the skin of a subject by a FTIR spectrometer coupled with a micro-imaging system.
    Type: Application
    Filed: July 23, 2010
    Publication date: May 17, 2012
    Applicant: Galderma Research & Development
    Inventor: Jean-Paul Ortonne
  • NOVEL BIAROMATIC COMPOUNDS THAT MODULATE PPARy TYPE RECEPTORS AND COSMETIC/PHARMACEUTICAL COMPOSITIONS COMPRISED THEREOF
    Publication number: 20120121527
    Abstract: Novel biaromatic compounds having the general formula (I): and cosmetic/pharmaceutical compositions comprised thereof are useful in human or veterinary medicine (in dermatology and also in the fields of cardiovascular diseases, of immune diseases and/of diseases related to the metabolism of lipids), or, alternatively, in cosmetic compositions.
    Type: Application
    Filed: January 18, 2012
    Publication date: May 17, 2012
    Applicant: Galderma Research & Development
    Inventors: Jean-Guy BOITEAU, Laurence Clary, Corinne Millois Barbuis
  • COMBINATION/ASSOCIATION OF ADAPALENE AND BENZOYL PEROXIDE FOR TREATING ACNE LESIONS
    Publication number: 20120115947
    Abstract: Acne lesions, whether of inflammatory and/or non-inflammatory type, are simultaneously or sequentially treated and their number reduced, via daily topical regimen, with the combination or association of adapalene or pharmaceutically acceptable salt thereof and benzoyl peroxide (BPO).
    Type: Application
    Filed: January 17, 2012
    Publication date: May 10, 2012
    Applicant: Galderma Research & Development
    Inventors: Marie-Line Abou Chacra Vernet, Denis Gross, Christian Loesche, Michel Poncet
  • RAR receptor agonist ligands and use thereof in human medicine and cosmetics
    Patent number: 8163952
    Abstract: The invention relates to compounds corresponding to general formula (I) below: to the compositions containing same, to methods for the preparation thereof and to the use thereof in pharmaceutical compositions for use in human or veterinary medicine, or else in cosmetic compositions.
    Type: Grant
    Filed: April 24, 2008
    Date of Patent: April 24, 2012
    Assignee: Galderma Research & Development
    Inventor: Thibaud Biadatti-Portal
  • METHOD FOR PREPARING MOLECULAR COMPLEXES BETWEEN ADAPALENE AND CYCLODEXTRINS
    Publication number: 20120077970
    Abstract: A method for preparing molecular complexes between Adapalene and cyclodextrins using the technology of dense fluids under pressure, especially that of CO2 is described.
    Type: Application
    Filed: April 9, 2010
    Publication date: March 29, 2012
    Applicant: Galderma Research & Development
    Inventors: Hubert Lochard, Bernard Freiss
  • COMBINATIONS OF ADAPALENE AND BENZOYL PEROXIDE FOR TREATING ACNE LESIONS
    Publication number: 20120059063
    Abstract: Adapalene or a pharmaceutically acceptable salt thereof formulated into a pharmaceutical composition is useful for reducing the number of acne lesions, via daily topical application, in combination or in association with benzoyl peroxide (BPO); such treatment may be via administration of a pharmaceutical composition combining adapalene and BPO or by a concomitant application of two pharmaceutical compositions, one containing adapalene and the other containing BPO.
    Type: Application
    Filed: November 14, 2011
    Publication date: March 8, 2012
    Applicant: Galderma Research & Development
    Inventors: Marie-line ABOU-CHACRA VERNET, Denis Gross, Christian Loesche, Michel Poncet
  • Combination/association of adapalene and benzoyl peroxide for treating acne lesions
    Patent number: 8129362
    Abstract: Acne lesions, whether of inflammatory and/or non-inflammatory type, are simultaneously or sequentially treated and their number reduced, via daily topical regimen, with the combination or association of adapalene or pharmaceutically acceptable salt thereof and benzoyl peroxide (BPO).
    Type: Grant
    Filed: July 13, 2007
    Date of Patent: March 6, 2012
    Assignee: Galderma Research & Development
    Inventors: Marie-Line Abou Chacra Vernet, Denis Gross, Christian Loesche, Michel Poncet