Abstract: Pharmaceutical/dermatological compositions containing at least one avermectin compound, e.g., ivermectin and hydrocortisone or salt, ester or derivative thereof, are useful for treating afflictions of the skin, especially rosacea.
Abstract: Metronidazole is solubilized in an aqueous phase, by mixing same with niacinamide and at least two glycolic cosolvents; the resulting solutions and pharmaceutical compositions comprised thereof are useful for the treatment of dermatological conditions/afflictions, notably rosacea.
Abstract: The slow and sustained, controlled release of a drug into and through the skin includes topically applying onto the skin of an individual in need of such treatment, a composition containing at least one solubilized drug, at least one film-forming silicone, and at least one volatile solvent.
Abstract: The invention relates to a pharmaceutical composition, especially a dermatological composition, containing, in a physiologically acceptable medium, at least one compound of the avermectin family, and benzoyl peroxide, and also to its use for the manufacture of a medicament for treating skin conditions, especially rosacea.
Abstract: Pharmaceutical/dermatological compositions useful for the prevention/treatment of disorders of the skin, especially rosacea, contain thus effective amounts of at least one avermectin compound, e.g., ivermectin, and at least one azelaic acid compound or salt or derivative thereof, formulated into a physiologically acceptable medium therefor.
Abstract: Topically applicable film-forming solutions, e.g., nail varnishes, useful for such dermatological applications as the prevention or treatment of nail psoriasis, contain, as active agents solubilized therein, vitamin D or derivative thereof and a corticosteroid, formulated into a topically applicable, physiologically acceptable medium therefor.
Abstract: The invention concerns a foaming composition for washing and treating hair and/or scalp essentially characterised in that it contains in an aqueous medium: at least an active principle selected among corticoids and retinoids; at least an anionic surfactant; at least an amphoteric surfactant; and a pro-penetrating agent.
Abstract: The invention concerns a foaming composition for washing and treating hair and/or scalp essentially characterized in that it contains in an aqueous medium: at least an active principle selected among corticoids and retinoids; at least an anionic surfactant; at least an amphoteric surfactant; and a pro-penetrating agent.
Abstract: A microdose of at least one active principle is essentially homogeneously formulated within at least one excipient therefor, via the following steps: 1. weighing the at least one active principle in a receptacle lined with a petroleum jelly; 2. encapsulating the active principle with additional petroleum jelly; 3. introducing the receptacle confining the active principle(s) and the petroleum jelly into a mixer, the receptacle being provided with perforations of a size and shape as to permit diffusion of the active principle(s) and petroleum jelly therethrough and the mixer containing at least one excipient in heated liquid state; and 4. melting said petroleum jelly by immersion of the receptacle within the at least one excipient in heated liquid state and thence diffusing and microdosing the active principle(s) therein.
Abstract: The present invention concerns a device for metering products intended to be applied to the skin, in particular pharmaceutical or cosmetic compositions. The invention relates more particularly to a device taking the form of an applicator stick, the graduations of which allow users to determine precisely the quantity of medication to be applied to the skin as a function of the surface area to be treated.
Abstract: Pharmaceutical cream-gel compositions useful for the treatment of a variety of dermatological conditions, disorders and afflictions, in particular of rosacea, contain at least one avermectin compound active principle, and which also contain an oily phase dispersed in an aqueous phase by means of a non-surfactant polymeric emulsifier, the oily phase comprising oils having a melting point below 30° C. and being free of solid fats having a melting point above 30° C., formulated into a physiologically acceptable medium therefor.
Abstract: The invention relates to a device to assist in quantifying a medicament for application on the skin, characterised in that it includes, on the one hand, a first element having a first window and at least one additional window and, on the other hand, a second element having a first graduation and at least one additional graduation, each graduation comprising successive values, the said first and second elements being superimposed and mounted so as to rotate with respect to each other about an axis of rotation so that, when the second element is rotated with respect to the first element, each additional window is arranged in front of one of the successive values of each additional graduation, as a function of the position of the first window relative to the successive values of the first graduation. The invention applies, in particular, to determining the quantity of a cream marketed under the brand name Silkis™.
Abstract: Topically applicable pharmaceutical compositions suited for the treatment of dermatological complaints, conditions or afflictions, notably rosacea, contain a thus effective amount of metronidazole and at least one dye effective to impart a green color thereto, formulated into a topically applicable, pharmaceutically acceptable vehicle therefor.
Abstract: Seborrheic dermatitis is effectively/safely treated by topically applying a corticosteroid shampoo, notably a clobetasol propionate shampoo, onto the scalp of a human subject afflicted therewith.
Type:
Application
Filed:
December 22, 2004
Publication date:
June 22, 2006
Applicant:
Galderma S.A.
Inventors:
Bistuer Florence, Christian Loesche, Pascale Soto
Abstract: A microdose of at least one active principle is essentially homogeneously formulated within at least one excipient therefor, via the following steps: 1. weighing the at least one active principle in a receptacle lined with a petroleum jelly; 2. encapsulating the active principle with additional petroleum jelly; 3. introducing the receptacle confining the active principle(s) and the petroleum jelly into a mixer, the receptacle being provided with perforations of a size and shape as to permit diffusion of the active principle(s) and petroleum jelly therethrough and the mixer containing at least one excipient in heated liquid state; and 4. melting said petroleum jelly by immersion of the receptacle within the at least one excipient in heated liquid state and thence diffusing and microdosing the active principle(s) therein.
Abstract: Dermatological conditions/afflictions such as rosacea, common acne, seborrheic dermatitis, perioral dermatitis, acneform rashes, transient acantholytic dermatosis, and acne necrotica miliaris, most notably rosacea, are treated by topically applying onto the affected skin area of an individual in need of such treatment, a topical pharmaceutical composition which comprises a thus effective amount of ivermectin.
Abstract: Topically applicable, pharmaceutical foam/mousse compositions, well suited for the treatment of psoriasis, include a hydrophobic phase, at least one surfactant, a therapeutically effective amount of a vitamin D analogue and a therapeutically effective amount of a corticosteroid.
Abstract: Topically applicable pharmaceutical compositions useful for the treatment of psoriasis contain respective amounts of calcitriol and clobetasol propionate permitting a once-per-day effective regimen of topical application onto the part or parts of the skin affected by psoriasis.
Abstract: Sprayable, anhydrous and physically/chemically stable dermatological/pharmaceutical compositions, well suited for the treatment of a variety of dermatological disorders, notably psoriasis, contain: a) a therapeutically effective amount of a solubilized corticoid, notably dissolved clobetasol propionate; b) a therapeutically effective amount of a solubilized vitamin D derivative, notably dissolved calcitriol; and c) an alcohol phase; and d) an oily phase which comprises one or more oils; formulated into e), a sprayable and topically applicable, dermatologically/pharmaceutically acceptable vehicle therefor.
Abstract: Topically applicable, anhydrous, hydrophobic and physically/chemically stable dermatological/pharmaceutical oleaginous ointments having effective release/penetration capacity and also having therapeutically effective amounts of calcitriol and clobetasol 17-propionate solubilized therein, are well suited for the treatment of psoriasis.