Abstract: Pharmaceutical/dermatological compositions useful for the prevention/treatment of disorders of the skin, especially rosacea, contain thus effective amounts of at least one avermectin compound, e.g., ivermectin, and at least one azelaic acid compound or salt or derivative thereof, formulated into a physiologically acceptable medium therefor.

Abstract: Dermatological medicament compositions contain a combination of hydroquinone, fluocinolone acetonide and tretinoin and are useful for the treatment of the hyperpigmentation of pathological scars, namely, hypertrophic scars and keloidal scars.

Abstract: Anhydrous sprayable pharamecutical/dermatological compositions containing, as active pharmaceutical agent, a corticoid, preferably clobetasol propionate, and an oily phase, are formulated in a physiologically acceptable medium, and are useful for the treatment of a variety of conditions and afflictions, notably psoriasis.

Abstract: A cream base for the topical application of skin care therapeutics and a process for making the cream base. In one embodiment, the therapeutic is tretinoin, hydroquinone and fluocinolone acetonide for the treatment of hyperpigmented skin conditions, such as melasma.

Abstract: Topical application of a triple combination immixture of fluocinolone acetonide, tretinoin and hydroquinone is useful for the maintenance therapy of melasma to prevent hyperpigmentation recurrence or reduce the severity of the hyperpigmentation recurrence.

Abstract: Topical application of a triple combination immixture of fluocinolone acetonide, tretinoin and hydroquinone is useful for the maintenance therapy of melasma to prevent hyperpigmentation recurrence or reduce the severity of the hyperpigmentation recurrence.

Abstract: A cream base for the topical application of skin care therapeutics and a process for making the cream base. In one embodiment, the therapeutic is tretinoin, hydroquinone and fluocinolone acetonide for the treatment of hyperpigmented skin conditions, such as melasma.

Abstract: Topically applicable, anhydrous and physically/chemically stable pharmaceutical compositions useful for the treatment of disorders of the skin, notably psoriasis, contain a silicone agent; a therapeutically effect amount of a compound A, which is vitamin D or derivative thereof, solubilized in a solvent therefor; and a therapeutically effective amount of a compound B, which is the corticosteroids, also solubilized in a solvent therefor.

Abstract: Pharmaceutical/dermatological compositions containing at least one avermectin compound, e.g., ivermectin and benzoyl peroxide, are useful for treating afflictions of the skin, especially rosacea.

Abstract: Pharmaceutical/dermatological compositions containing at least one avermectin compound, e.g., ivermectin and metronidazole or salt, ester or derivative thereof, are useful for treating afflictions of the skin, especially rosacea.

Abstract: Pharmaceutical/dermatological compositions containing at least one avermectin compound, e.g., ivermectin and benzoyl peroxide, are useful for treating afflictions of the skin, especially rosacea.

Abstract: A process for the preparation of a compound of formula (Ib): including contacting a compound of formula (Ia): with toluene and HCl gas to provide the compound of formula (Ib).

Abstract: A regime or regimen for the treatment of a nail disease state includes topically applying onto the infected nail(s) of an individual a thus effective amount of a solution of amorolfine in ionized form and concomitantly applying thereto an iontophoretic current of such intensity as to deliver the amorolfine into and/or through the infected nail(s).

Abstract: The invention relates to a device to assist in quantifying a medicament for application on the skin, characterized in that it includes, on the one hand, a first element having a first window and at least one additional window and, on the other hand, a second element having a first graduation and at least one additional graduation, each graduation comprising successive values, the said first and second elements being superimposed and mounted so as to rotate with respect to each other about an axis of rotation so that, when the second element is rotated with respect to the first element, each additional window is arranged in front of one of the successive values of each additional graduation, as a function of the position of the first window relative to the successive values of the first graduation. The invention applies, in particular, to determining the quantity of a cream marketed under the brand name Silkis™.

Abstract: The invention concerns a foaming composition for washing and treating hair and/or scalp essentially characterised in that it contains in an aqueous medium: at least an active principle selected among corticoids and retinoids; at least an anionic surfactant; at least an amphoteric surfactant; and a pro-penetrating

Abstract: A process for the preparation of a compound of formula (Ia): includes: (i) contacting a compound of formula (III): with a compound of formula (IV): in the presence of a palladium catalyst, methanol and hydrogen gas, the step (i) preferably being conducted under basic conditions with acetic acid being added to the medium of reaction once the consumption of the hydrogen gas has ceased.

Abstract: Dermatological/pharmaceutical compositions contain lipid vesicles dispersed in a hydrophilic phase, such vesicles including at least one vitamin D compound and particularly calcitriol, and are useful for the treatment of dermatological pathologies, notably psoriasis.

Abstract: The slow and sustained, controlled release of a drug into and through the skin includes topically applying onto the skin of an individual in need of such treatment, a composition containing at least one solubilized drug, at least one film-forming silicone, and at least one volatile solvent.

Abstract: A microdose of at least one active principle is homogeneously formulated as an ointment using a container with perforations having a size and shape that permit diffusion of the active principle(s) and petroleum jelly through the perforations, by: (a) weighing the at least one active principle in a container lined with a petroleum jelly; (b) encapsulating the active principle with additional petroleum jelly; (c) introducing the container with the active principle(s) and the petroleum jelly into a mixer, where the mixer contains at least one excipient in a heated liquid state; and (d) immersing the container within the at least one excipient in a heated liquid state, thereby melting the petroleum jelly, which causes diffusion of the active principal(s) and the melted petroleum jelly and microdoses the active principle(s) in the excipients.

Abstract: Stable, topically applicable, non-greasy and non-tacky oil-in-water (O/W) anti-inflammatory emulsions, useful, e.g., for the treatment of psoriasis, contain: a. a therapeutically effective amount of at least one steroidal anti-inflammatory agent, notably clobetasol propionate; b. a pro-penetrating system which includes at least one pro-penetrating glycol and at least one other pro-penetrating agent; and c. at least one polymeric emulsifier not sensitive to electrolytes, for example not an acrylate/C10-C30 alkyl acrylate copolymer, formulated into a topically applicable, pharmaceutically acceptable vehicle therefor.