Patents Assigned to GENO LLC
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Publication number: 20150314100Abstract: Various systems and devices for generating nitric oxide are disclosed herein. According to one embodiment, the device includes a body having an inlet, an outlet, and a porous solid matrix positioned with the body. The porous solid matrix is coated with an aqueous solution of an antioxidant, wherein the inlet is configured to receive a gas flow and fluidly communicate the gas flow to the outlet through the solid matrix to convert nitrogen dioxide in the gas flow into nitric oxide. The porous solid matrix allows the device to be used in any orientation. Additionally, the porous solid matrix provides a rigid structure suitable to withstand vibrations and abuse without compromising device functionality.Type: ApplicationFiled: February 2, 2015Publication date: November 5, 2015Applicant: GENO LLCInventors: David H. Fine, Bryan Johnson, Gregory Vasquez
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Patent number: 8944049Abstract: Various systems and devices for generating nitric oxide are disclosed herein. According to one embodiment, the device includes a body having an inlet, an outlet, and a porous solid matrix positioned with the body. The porous solid matrix is coated with an aqueous solution of an antioxidant, wherein the inlet is configured to receive a gas flow and fluidly communicate the gas flow to the outlet through the solid matrix to convert nitrogen dioxide in the gas flow into nitric oxide. The porous solid matrix allows the device to be used in any orientation. Additionally, the porous solid matrix provides a rigid structure suitable to withstand vibrations and abuse without compromising device functionality.Type: GrantFiled: December 16, 2013Date of Patent: February 3, 2015Assignee: GENO LLCInventors: David H. Fine, Bryan Johnson, Gregory Vasquez
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Publication number: 20150007814Abstract: A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.Type: ApplicationFiled: May 5, 2014Publication date: January 8, 2015Applicant: GENO LLCInventors: David H. Fine, David R. Rounbehler, Gregory Vasquez, Brian Johnson
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Patent number: 8887720Abstract: A system for delivering a therapeutic amount of nitric oxide can include a reservoir including a restrictor with a length of at least 0.5 inch and at most 2 inches covered by a metal sheath, a gas supply, and a delivery conduit. A delivery conduit can include at least one cartridge and a patient interface. The at least one cartridge can include a surface-active material and a reducing agent.Type: GrantFiled: April 26, 2011Date of Patent: November 18, 2014Assignee: Geno LLCInventors: David H. Fine, Gregory Vasquez, Bryan Johnson, Ryan Denton, Lucas G. Gamero
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Patent number: 8821801Abstract: A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.Type: GrantFiled: August 16, 2012Date of Patent: September 2, 2014Assignee: Geno LLCInventors: David R. Rounbehler, David H. Fine
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Patent number: 8741222Abstract: Various systems, devices, NO2 absorbents, NO2 scavengers and NO2 recuperator for generating nitric oxide are disclosed herein. According to one embodiment, an apparatus for converting nitrogen dioxide to nitric oxide can include a receptacle including an inlet, an outlet, a surface-active material coated with an aqueous solution of ascorbic acid and an absorbent wherein the inlet is configured to receive a gas flow and fluidly communicate the gas flow to the outlet through the surface-active material and the absorbent such that nitrogen dioxide in the gas flow is converted to nitric oxide.Type: GrantFiled: December 16, 2013Date of Patent: June 3, 2014Assignee: Geno LLCInventors: David H. Fine, Gregory Vasquez, David P. Rounbehler
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Patent number: 8715577Abstract: A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.Type: GrantFiled: March 30, 2012Date of Patent: May 6, 2014Assignee: Geno LLCInventors: David H. Fine, David P. Rounbehler, Gregory Vasquez, Bryan Johnson
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Patent number: 8701657Abstract: In one aspect, a system for delivering nitric oxide to a patient can include a first gas source including nitrogen dioxide mixed in air or oxygen, a second gas source supplying compressed air, a ventilator coupled to the first and second gas sources, where the ventilator can be resistant to nitrogen dioxide, and where the ventilator provides a gas flow having a proper amount of nitrogen dioxide, one or more conversion devices operably coupled to the ventilator, where the conversion devices covert nitrogen dioxide into nitric oxide, and a patient interface operably coupled to the conversion devices, where the patient interface delivers nitric oxide to the patient.Type: GrantFiled: August 13, 2009Date of Patent: April 22, 2014Assignee: Geno LLCInventors: David H. Fine, Gregory Vasquez, Bryan Johnson
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Patent number: 8646445Abstract: An ambulatory or stationary device for delivery of a therapeutic amount of nitric oxide to an individual's lungs.Type: GrantFiled: November 22, 2010Date of Patent: February 11, 2014Assignee: Geno LLCInventors: David H. Fine, Gregory Vasquez, Bryan Johnson, Jody Fuller, Ryan Denton
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Patent number: 8613958Abstract: A method for delivering nitric oxide therapy to a subject can include administering a composition including a nitric-oxide releasing agent and silica to the subject and releasing a therapeutic amount of nitric oxide from the composition.Type: GrantFiled: June 21, 2010Date of Patent: December 24, 2013Assignee: GENO LLCInventor: David H. Fine
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Patent number: 8609026Abstract: Various systems, devices, NO2 absorbents, NO2 scavengers and NO2 recuperator for generating nitric oxide are disclosed herein. According to one embodiment, an apparatus for converting nitrogen dioxide to nitric oxide can include a receptacle including an inlet, an outlet, a surface-active material coated with an aqueous solution of ascorbic acid and an absorbent wherein the inlet is configured to receive a gas flow and fluidly communicate the gas flow to the outlet through the surface-active material and the absorbent such that nitrogen dioxide in the gas flow is converted to nitric oxide.Type: GrantFiled: May 24, 2012Date of Patent: December 17, 2013Assignee: GENO LLCInventors: David Fine, Gregory Vasquez, David P. Rounbehler
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Patent number: 8607785Abstract: Various systems and devices for generating nitric oxide are disclosed herein. According to one embodiment, the device includes a body having an inlet, an outlet, and a porous solid matrix positioned with the body. The porous solid matrix is coated with an aqueous solution of an antioxidant, wherein the inlet is configured to receive a gas flow and fluidly communicate the gas flow to the outlet through the solid matrix to convert nitrogen dioxide in the gas flow into nitric oxide. The porous solid matrix allows the device to be used in any orientation. Additionally, the porous solid matrix provides a rigid structure suitable to withstand vibrations and abuse without compromising device functionality.Type: GrantFiled: August 13, 2009Date of Patent: December 17, 2013Assignee: Geno LLCInventors: David H. Fine, Bryan Johnson, Gregory Vasquez
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Patent number: 8609028Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. A nitric oxide delivery system that converts nitrogen dioxide to nitric oxide employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid.Type: GrantFiled: July 23, 2012Date of Patent: December 17, 2013Assignee: Geno LLCInventors: David R. Rounbehler, David H. Fine
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Patent number: 8371296Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. Precise delivery of nitric oxide at therapeutic levels of 20 to 100 ppm and inhibition of reaction of nitric oxide with oxygen to form toxic impurities such as nitrogen dioxide can provide effective inhalation therapy for pulmonary hypertension.Type: GrantFiled: May 8, 2006Date of Patent: February 12, 2013Assignee: Geno, LLCInventors: David H. Fine, Stephen J. MacDonald, David Rounbehler, David Wheeler, Jonathan L. Rolfe, George Jarvis
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Patent number: 8268252Abstract: A unique combination of male and female gas connectors for one way transfer of gasses.Type: GrantFiled: April 26, 2011Date of Patent: September 18, 2012Assignee: GENO LLCInventors: Jody Fuller, David H. Fine
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Patent number: 8246725Abstract: A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.Type: GrantFiled: October 7, 2011Date of Patent: August 21, 2012Assignee: Geno LLCInventors: David R. Rounbehler, David H. Fine
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Patent number: 8226916Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. A nitric oxide delivery system that converts nitrogen dioxide to nitric oxide employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid.Type: GrantFiled: November 17, 2011Date of Patent: July 24, 2012Assignee: Geno LLCInventors: David R. Rounbehler, David H. Fine
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Patent number: 8221800Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. Precise delivery of nitric oxide at therapeutic levels of 20 to 100 ppm and inhibition of reaction of nitric oxide with oxygen to form toxic impurities such as nitrogen dioxide can provide effective inhalation therapy for pulmonary hypertension.Type: GrantFiled: April 7, 2006Date of Patent: July 17, 2012Assignee: Geno LLCInventors: David H. Fine, Stephen J. MacDonald, David R. Rounbehler, David Wheeler, Jonathan L. Rolfe, George Jarvis
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Patent number: D679366Type: GrantFiled: April 27, 2010Date of Patent: April 2, 2013Assignee: Geno LLCInventor: Jody Fuller
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Patent number: D688352Type: GrantFiled: April 27, 2010Date of Patent: August 20, 2013Assignee: Geno LLCInventor: Jody Fuller