Abstract: The invention provides for peptides from the Mucin 1 (MUC1) cytoplasmic domain and methods of use therefor. These peptides can inhibit MUC1 oligomerization, thereby preventing tumor cell growth, inducing tumor cell apoptosis and necrosis of tumor tissue in vivo.
Type:
Grant
Filed:
October 16, 2009
Date of Patent:
September 3, 2013
Assignees:
Dana-Farber Cancer Institute, Inc., Genus Oncology, LLC