Abstract: The present disclosure relates generally to systems and methods for the photo-inactivation of microorganisms. More specifically, the present invention is directed towards the photo-inactivation of microorganisms, such as viruses, using at least one furanocoumarin and broad spectrum pulsed light. For example, an aspect of the present invention includes a method for inactivating a herpesvirus, such as herpes B virus or herpes virus papio 2 using a psoralen and broad spectrum pulsed light.
Type:
Application
Filed:
December 20, 2010
Publication date:
October 25, 2012
Applicant:
GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION
Abstract: Systems and methods are disclosed with which queries can be sent to various clients of a trusted query network in a trusted query network message. In one embodiment, each registered client receives the message and determines whether or not it will participate in the query. If so, the client adds to the message in a first data round a true response to the query and obfuscation data, and then forwards the message on to the next client (or back to the client that initiated the query if each client has added its data to the message). In a second round, the message is again sent to each participating client, which this time removes its obfuscation data. Once each client has removed its obfuscation data, a final result is obtained that can be sent to each of the clients.
Type:
Application
Filed:
July 16, 2010
Publication date:
July 12, 2012
Applicant:
GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
Inventors:
Richard Baskerville, Art Vandenberg, Daniele Bertolotti, Saravanaraj Duraisamy
Abstract: A composition, reactor apparatus, method, and control system for growing epitaxial layers of group III-nitride alloys. Super-atmospheric pressure is used as a process parameter to control the epitaxial layer growth where the identity of alloy layers differ within a heterostructure stack of two or more layers.
Type:
Application
Filed:
August 12, 2010
Publication date:
June 7, 2012
Applicant:
GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
Abstract: Novel aza analogues of dicationic terphenyl compounds for use in combating microbial infections are described. The compounds include those of Formula (III): wherein one of A1, Y1, and Z1 is N; Ar1 is phenylene; and Ar3 is a nitrogen-containing aromatic group.
Type:
Grant
Filed:
June 17, 2011
Date of Patent:
May 29, 2012
Assignees:
The University of North Carolina at Chapel Hill, Georgia State University Research Foundation, Inc.
Inventors:
Richard R. Tidwell, David W. Boykin, W. David Wilson, Reto Brun, Karl Werbovetz, Mohamed A. Ismail, Reem K. Arafa, Laixing Hu
Abstract: Disclosed herein are compounds suitable for use as antitumor agents, methods for treating cancer wherein the disclosed compounds are used in making a medicament for the treatment of cancer, methods for treating a tumor comprising, administering to a subject a composition comprising one or more of the disclosed cytotoxic agents, and methods for preparing the disclosed antitumor agents.
Type:
Application
Filed:
May 7, 2010
Publication date:
May 17, 2012
Applicants:
SHANDONG UNIVERSITY, GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION
Inventors:
Wen Fang Xu, Hao Fang, Yan Ling Li, Binghe Wang
Abstract: The present invention provides selenium derivatives of nucleosides, nucleoside phosphoramidites, nucleotides, nucleotide triphosphates, oligonucleotides, polynucleotides, and larger nucleic acids and methods for their synthesis. Selenium derivatives of both ribonucleic acids and deoxyribonucleic acids, as well as methods for their synthesis, crystallization and uses in structural determinations, particularly by X-ray crystallographic techniques are disclosed. The selenium derivatives of the present invention are also useful as food supplements.
Type:
Application
Filed:
June 29, 2011
Publication date:
March 15, 2012
Applicant:
GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
Abstract: The invention relates to the innate immune pathway and anti-inflammatory molecules with therapeutic properties. In some embodiments, the invention relates to compounds and pharmaceutical compositions and methods of using the compounds and compositions to treat inflammatory diseases including inflammation associated with auto-immune diseases.
Type:
Application
Filed:
August 24, 2011
Publication date:
March 1, 2012
Applicants:
GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, EMORY UNIVERSITY
Inventors:
Susu Zughaier, Ritu Aneja, David S. Stephens
Abstract: The present invention relates to compositions for and methods of optically imaging tissues or cells using imaging agents having desirable in vivo properties that result in improved signal-to-background ratio.
Type:
Application
Filed:
February 5, 2010
Publication date:
February 2, 2012
Applicants:
GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC., BETH ISRAEL DEACONESS MEDICAL CENTER, INC.
Abstract: Novel aza analogues of dicationic terphenyl compounds for use in combating microbial infections are described. Also described are processes for synthesizing the compounds.
Type:
Grant
Filed:
May 17, 2006
Date of Patent:
January 24, 2012
Assignees:
The University of North Carolina at Chapel Hill, Georgia State University Research Foundation, Inc.
Inventors:
Richard R. Tidwell, David W. Boykin, W. David Wilson, Reto Brun, Karl Werbovetz, Mohamed A. Ismail, Reem K. Arafa
Abstract: A dual band photodetector for detecting infrared and ultraviolet optical signals is disclosed. Aspects include homojunction and heterojunction detectors comprised of one or more of GaN, AlGaN, and InGaN. In one aspect ultraviolet/infrared dual-band detector is disclosed that is configured to simultaneously detect UV and IR.
Type:
Grant
Filed:
October 19, 2010
Date of Patent:
January 10, 2012
Assignee:
Georgia State University Research Foundation, Inc.
Inventors:
A. G. Unil Perera, Steven George Matsik
Abstract: In one embodiment, facilitating classroom interaction includes sending a message containing a question to be answered from a mobile device located within a classroom at which a class is being taught, receiving the message with a central server and identifying the class to which the message pertains, and displaying the question on a display device located within the classroom.
Type:
Application
Filed:
June 7, 2011
Publication date:
December 8, 2011
Applicant:
Georgia State University Research Foundation
Abstract: A nanostructure is used to generate a highly localized nanoscale optical field. The field is excited using surface plasmon amplification by stimulated emission of radiation (SPASER). The SPASER radiation consists of surface plasmons that undergo stimulated emission, but in contrast to photons can be localized within a nanoscale region. A SPASER can incorporate an active medium formed by two-level emitters, excited by an energy source, such as an optical, electrical, or chemical energy source. The active medium may be quantum dots, which transfer excitation energy by radiationless transitions to a resonant nanosystem that can play the same role as a laser cavity in a conventional laser. The transitions are stimulated by the surface plasmons in the nanostructure, causing the buildup of a macroscopic number of surface plasmons in a single mode.
Type:
Grant
Filed:
April 30, 2009
Date of Patent:
September 13, 2011
Assignees:
Ramot At Tel-Aviv University Ltd, The Georgia State University Research Foundation
Abstract: The present invention is directed to methods for delaying a plant development process comprising exposing a plant or plant part to one or more bacteria or enzymes. In specific embodiments, the one or more bacteria are selected from the group consisting of Rhodococcus spp., Pseudomonas chloroaphis, Brevibacterium ketoglutamicum, and a mixture comprising any combination of these bacteria. Apparatuses for delaying a plant development process comprising a catalyst that comprises one or more of the above bacteria.
Type:
Application
Filed:
April 11, 2011
Publication date:
July 28, 2011
Applicant:
GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
Inventors:
George E. Pierce, Sangeeta Ganguly, Gene K. Drago
Abstract: The present invention provides selenium derivatives of nucleosides, nucleoside phosphoramidites, nucleotides, nucleotide triphosphates, oligonucleotides, polynucleotides, and larger nucleic acids and methods for their synthesis. Selenium derivatives of both ribonucleic acids and deoxyribonucleic acids, as well as methods for their synthesis, crystallization and uses in structural determinations, particularly by X-ray crystallographic techniques are disclosed. The selenium derivatives of the present invention are also useful as food supplements.
Type:
Grant
Filed:
September 18, 2009
Date of Patent:
July 19, 2011
Assignee:
Georgia State University Research Foundation, Inc.
Abstract: Disclosed herein are antimicrobial compositions, kits, and articles of manufacture. Further disclosed herein are methods for treating surfaces, including tissue, inter alia, wounds, with the disclosed compositions.
Type:
Application
Filed:
July 27, 2009
Publication date:
July 7, 2011
Applicant:
GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC
Inventors:
Charles Derby, Binghe Wang, Phang C. Tai, Ko-Chun Ko, Michiya Kamio
Abstract: Disclosed herein are novel dicationic teraryl compounds and their aza analogues, including compounds of Formula (IIe): wherein p and q are each 0 and each A, Y and Z is CR4. An exemplary compound of Formula (IIe) is: Methods for combating microbial infections, such as parasitic Leishmania species, with novel dicationic terphenyl compounds and their aza analogues are included. Processes for synthesizing novel dicationic terphenyl compounds and their aza analogues are disclosed along with methods for evaluation of the compounds as potential anti-protozoan agents.
Type:
Grant
Filed:
January 25, 2007
Date of Patent:
June 21, 2011
Assignees:
The University of North Carolina at Chapel Hill, Georgia State University Research Foundation, Inc.
Inventors:
Richard R. Tidwell, David W. Boykin, W. David Wilson, Reto Brun, Laixing Hu, Karl Werbovetz, Mohamed A. Ismail, Reem K. Arafa
Abstract: The present invention is directed to methods for delaying a plant development process comprising exposing a plant or plant part to one or more bacteria or enzymes. In specific embodiments, the one or more bacteria are selected from the group consisting of Rhodococcus spp., Pseudomonas chloroaphis, Brevibacterium ketoglutamicum, and a mixture comprising any combination of these bacteria. Apparatuses for delaying a plant development process comprising a catalyst that comprises one or more of the above bacteria.
Type:
Grant
Filed:
April 2, 2007
Date of Patent:
May 17, 2011
Assignee:
Georgia State University Research Foundation, Inc.
Inventors:
George E. Pierce, Sangeeta Ganguly, Gene K. Drago
Abstract: A dual band photodetector for detecting infrared and ultraviolet optical signals is disclosed. Aspects include homojunction and heterojunction detectors comprised of one or more of GaN, AlGaN, and InGaN. In one aspect ultraviolet/infrared dual-band detector is disclosed that is configured to simultaneously detect UV and IR.
Type:
Application
Filed:
October 19, 2010
Publication date:
March 3, 2011
Applicant:
GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC.