Patents Assigned to Glaukos Corporation
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Patent number: 8070290Abstract: Various embodiments relate to opthalmoscopic devices, systems and methods for viewing the anterior chamber, trabecular meshwork, iris root, scleral spur, and/or related nearby structures in the eye. In some embodiments, devices, systems and/or methods may employ a plurality of gonioscopic optical elements that form a virtual image that can be imaged by a microscope directly in front of a patient (e.g., without tilting the patient's head). Various embodiments described herein may be useful for ophthalmologic diagnoses, treatments, monitoring and/or surgical procedures. Some embodiments include a gonioscopic attachment configured to attach to a conventional gonioscope and redirect light emitted by the gonioscope. Various embodiments described herein can be incorporated into disposable, single-use gonioscopes.Type: GrantFiled: December 16, 2009Date of Patent: December 6, 2011Assignee: Glaukos CorporationInventors: Henrick K. Gille, Leslie Dale Foo, James Patrick McGuire, Jr.
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Patent number: 8062244Abstract: Implants and methods for treating ocular disorders are disclosed. One implant has a tubular member, with inlet and outlet ends, and a cutting member connected thereto. The tubular member is configured to extend through eye tissue such that the inlet and outlet ends reside respectively in an anterior chamber and a physiologic outflow pathway of the eye. Desirably, the cutting member is configured to make an incision in the eye tissue for receiving at least a portion of the tubular member. One method involves introducing an implant, with proximal and distal ends, into the anterior chamber and penetrating eye tissue using an implant distal portion. The implant is advanced from the anterior chamber into the penetrated eye tissue to locate the distal and proximal ends respectively in the physiologic outflow pathway and the anterior chamber. Aqueous humor is conducted between the proximal and distal ends.Type: GrantFiled: February 5, 2009Date of Patent: November 22, 2011Assignee: Glaukos CorporationInventors: Hosheng Tu, Gregory T Smedley, David Haffner, Barbara A Niksch
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Patent number: 8007459Abstract: Devices and methods for treating ocular disorders are disclosed. One ocular implant, has a substantially straight, rigid, elongate body. The body has a self-trephinating distal portion that narrows toward a distal end, and at least one inlet that communicates with at least one inner lumen that communicates with a plurality of outlets. The lumen has a sufficient length to extend from an anterior chamber of an eye to a physiologic outflow pathway. An anchor member extends from the implant.Type: GrantFiled: December 18, 2008Date of Patent: August 30, 2011Assignee: Glaukos CorporationInventors: David S. Haffner, Gregory T. Smedley, Thomas W. Burns, Hosheng Tu
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Publication number: 20110196281Abstract: Shunt devices and a method for continuously decompressing elevated intraocular pressure in eyes affected by glaucoma by diverting excess aqueous humor from the anterior chamber of the eye into Schlemm's canal where post-operative patency can be maintained with an indwelling shunt device which surgically connects the canal with the anterior chamber. The shunt devices provide uni- or bi-directional flow of aqueous humor into Schlemm's canal.Type: ApplicationFiled: December 13, 2010Publication date: August 11, 2011Applicant: GLAUKOS CORPORATIONInventors: Mary G. Lynch, Reay H. Brown
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Patent number: 7951155Abstract: A method is provided for treatment of cataract in combination with a glaucoma procedure while maintaining the intraocular pressure by permitting aqueous to flow out of an anterior chamber of the eye through a surgically stented pathway. A trabecular stent is adapted for implantation within the trabecular meshwork of an eye such that intraocular liquid flows controllably from the anterior chamber of the eye to Schlemm's canal, bypassing the trabecular meshwork. Depending upon the specific treatment contemplated, pharmaceuticals may be utilized in conjunction with the trabecular stent enabling post-cataract healing processes.Type: GrantFiled: January 16, 2007Date of Patent: May 31, 2011Assignee: Glaukos CorporationInventors: Gregory T. Smedley, David Haffner, Barbara Niksch, Hosheng Tu, Thomas W. Burns
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Publication number: 20110105987Abstract: Surgical methods and related medical devices for treating ocular disorders are disclosed. Some methods relate to delivering an implant within an eye, and involve providing an elongate guide device, such as, a flexible guide member or a guide wire. A distal end of the guide device can be advanced into an anterior chamber of an eye, or through at least a portion of a site of resistance along a physiologic outflow pathway of the eye, or from an anterior chamber of the eye to a location proximate a physiologic outflow pathway of the eye. The implant is advanced along the guide device toward the guide device distal end, and is positioned to conduct aqueous humor between the anterior chamber and the physiologic outflow pathway.Type: ApplicationFiled: October 28, 2010Publication date: May 5, 2011Applicant: GLAUKOS CORPORATIONInventors: Olav B. Bergheim, Morteza (Mory) Gharib
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Publication number: 20110092878Abstract: Systems and methods for treating ocular disorders are disclosed. One system has a delivery instrument, with a non-linear axis, configured to be inserted into an anterior chamber of an eye and moved to a location proximate a physiologic outflow pathway of the eye. The delivery instrument carries an implant that has a distal end sized for insertion into tissue such that aqueous humor drains from the anterior chamber to the physiologic outflow pathway. One method involves inserting a non-linear portion of a delivery device into the anterior chamber to position an implant within the eye. Another method involves using a delivery device with a curved distal portion to implant an implant at a location communicating with the physiologic outflow pathway. The delivery can be through a corneal incision and the implant can comprise a drug.Type: ApplicationFiled: December 27, 2010Publication date: April 21, 2011Applicant: GLAUKOS CORPORATIONInventors: Hosheng Tu, Gregory T Smedley, David Haffner, Barbara A. Niksch
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Patent number: 7879001Abstract: Intraocular implants and delivery instruments are disclosed for treating ophthalmic conditions and ocular disorders, such as glaucoma. The implants are configured to extend between the anterior chamber of the eye and a fluid outflow path or physiologic outflow pathway, such as Schlemm's canal, of the eye for enhancing outflow of aqueous from the anterior chamber so as to reduce intraocular pressure. The implants can have features for anchoring the implant into the physiologic outflow pathway as well as preventing the walls of the physiologic outflow pathway from closing the outlet of the implants. The delivery instruments can be steerable so as to make implantation easier. Additionally, the delivery instruments can be configured to hold a plurality of implants so that multiple implants can be implanted through one incision without removing the delivery instrument from the incision between serial implantations.Type: GrantFiled: August 8, 2007Date of Patent: February 1, 2011Assignee: Glaukos CorporationInventors: David Haffner, Gregory T Smedley, Hosheng Tu
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Patent number: 7879079Abstract: Surgical methods and related medical devices for treating glaucoma are disclosed. The method comprises trabecular bypass surgery, which involves bypassing diseased trabecular meshwork with the use of a stent implant. The stent implant is inserted into an opening created in the trabecular meshwork by a piercing member that is slidably advanceable through the lumen of the stent implant for supporting the implant insertion. The stent implant is positioned through the trabecular meshwork so that an inlet end of the stent implant is exposed to the anterior chamber of the eye and an outlet end is positioned into fluid collection channels at about an exterior surface of the trabecular meshwork or up to the level of aqueous veins.Type: GrantFiled: June 19, 2006Date of Patent: February 1, 2011Assignee: Glaukos CorporationInventors: Hosheng Tu, David S. Haffner, Gregory T. Smedley, Barbara A. Niksch, Morteza Gharib
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Patent number: 7867205Abstract: Surgical methods and related medical devices for treating ocular disorders are disclosed. Some methods relate to delivering an implant within an eye, and involve providing an elongate guide device, such as, a flexible guide member or a guide wire. A distal end of the guide device can be advanced into an anterior chamber of an eye, or through at least a portion of a site of resistance along a physiologic outflow pathway of the eye, or from an anterior chamber of the eye to a location proximate a physiologic outflow pathway of the eye. The implant is advanced along the guide device toward the guide device distal end, and is positioned to conduct aqueous humor between the anterior chamber and the physiologic outflow pathway.Type: GrantFiled: May 6, 2005Date of Patent: January 11, 2011Assignee: Glaukos CorporationInventors: Olav B. Bergheim, Morteza (Mory) Gharib
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Patent number: 7867186Abstract: Intraocular implants and delivery instruments are disclosed for treating ophthalmic conditions and ocular disorders, such as glaucoma. The implants are configured to extend between the anterior chamber of the eye and a fluid outflow path or physiologic outflow pathway, such as Schlemm's canal, of the eye for enhancing outflow of aqueous from the anterior chamber so as to reduce intraocular pressure. The implants can have features for anchoring the implant into Schlemm's canal as well as preventing the walls of Schlemm's canal from closing the outlet of the implants. The delivery instruments can be steerable so as to make implantation easier. Additionally, the instruments can be configured to hold a plurality of implants so that multiple implants can be implanted through one incision without removing the instrument from the incision between serial implantations.Type: GrantFiled: August 5, 2003Date of Patent: January 11, 2011Assignee: Glaukos CorporationInventors: David Haffner, Gregory T. Smedley, Hosheng Tu
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Patent number: 7857782Abstract: Systems and methods for treating ocular disorders are disclosed. One system has a delivery instrument, with a non-linear axis, configured to be inserted into an anterior chamber of an eye and moved to a location proximate a physiologic outflow pathway of the eye. The delivery instrument carries an implant that has a distal end sized for insertion into tissue such that aqueous humor drains from the anterior chamber to the physiologic outflow pathway. One method involves inserting a non-linear portion of a delivery device into the anterior chamber to position an implant within the eye. Another method involves using a delivery device with a curved distal portion to implant an implant at a location communicating with the physiologic outflow pathway. The delivery can be through a corneal incision and the implant can comprise a drug.Type: GrantFiled: February 5, 2009Date of Patent: December 28, 2010Assignee: Glaukos CorporationInventors: Hosheng Tu, Gregory T Smedley, David Haffner, Barbara A Niksch
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Patent number: 7850637Abstract: Shunt devices and a method for continuously decompressing elevated intraocular pressure in eyes affected by glaucoma by diverting excess aqueous humor from the anterior chamber of the eye into Schlemm's canal where post-operative patency can be maintained with an indwelling shunt device which surgically connects the canal with the anterior chamber. The shunt devices provide uni- or bi-directional flow of aqueous humor into Schlemm's canal.Type: GrantFiled: November 12, 2004Date of Patent: December 14, 2010Assignee: Glaukos CorporationInventors: Mary G. Lynch, Reay H. Brown
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Publication number: 20100265461Abstract: Various embodiments relate to opthalmoscopic devices, systems and methods for viewing the anterior chamber, trabecular meshwork, iris root, scleral spur, and/or related nearby structures in the eye. In some embodiments, devices, systems and/or methods may employ a plurality of gonioscopic optical elements that form a virtual image that can be imaged by a microscope directly in front of a patient (e.g., without tilting the patient's head). Various embodiments described herein may be useful for opthalmologic diagnoses, treatments, monitoring and/or surgical procedures. Some embodiments include a gonioscopic attachment configured to attach to a conventional gonioscope and redirect light emitted by the gonioscope. Various embodiments described herein can be incorporated into disposable, single-use gonioscopes.Type: ApplicationFiled: December 16, 2009Publication date: October 21, 2010Applicant: Glaukos CorporationInventors: Henrick K. Gille, Leslie Dale Foo, James Patrick McGuire, JR.
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Publication number: 20100234790Abstract: Implants and methods for treating ocular disorders are provided. One method involves introducing an implant into an anterior chamber of an eye such that at least a distal end of the implant is temporarily in the anterior chamber. The implant is implanted into eye tissue adjacent the anterior chamber. A therapeutic agent is eluted from the implant into at least one of the anterior chamber, a physiologic outflow pathway of the eye, and a space adjacent a choroid of the eye. The therapeutic agent can be an antiproliferative agent, an anti-inflammatory drug, or a compound for treating glaucoma or ocular hypertension. The therapeutic agent can be contained within the implant or coated on the implant.Type: ApplicationFiled: May 3, 2010Publication date: September 16, 2010Applicant: GLAUKOS CORPORATIONInventors: Hosheng Tu, Barbara Niksch, David Haffner, Gregory Smedley, Olav B. Bergheim, Morteza (Mory) Gharib
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Publication number: 20100234791Abstract: A shunt is provided for the flow of aqueous humor from the anterior chamber of the eye to Schlemm's canal and to other anatomical spaces of the eye. The shunt comprises at least one lumen and optionally has at least one anchor extending from a proximal portion of the shunt to assist in placement and anchoring of the device in the correct anatomic position.Type: ApplicationFiled: May 21, 2010Publication date: September 16, 2010Applicant: Glaukos CorporationInventors: Mary G. Lynch, Reay H. Brown, Guido Smeets
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Patent number: 7708711Abstract: Devices and methods are provided for the treatment of ocular disorders. An ocular implant has a body comprising material that includes a therapeutic drug. The body has an inlet portion and an outlet portion. The inlet portion is configured to reside in an anterior chamber of an eye when the outlet portion is disposed in a physiological outflow pathway of the eye. The outlet portion has an outflow opening such that the body drains fluid from the anterior chamber to the physiological outflow pathway. One method of treating an ocular disorder involves introducing an implant comprising a therapeutic drug into the eye such that the implant drains aqueous humor into a physiological outflow pathway and the therapeutic drug reaches eye tissue.Type: GrantFiled: November 12, 2003Date of Patent: May 4, 2010Assignee: Glaukos CorporationInventors: Hosheng Tu, Barbara Niksch, David Haffner, Gregory Smedley, Olav B. Bergheim, Morteza (Mory) Gharib
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Publication number: 20100106073Abstract: The invention discloses a trabecular stent and methods for treating glaucoma. The stent may incorporate an intraocular pressure sensor comprising a compressible element that is implanted inside an anterior chamber of an eye, wherein at least one external dimension of the element correlates with intraocular pressure. In some embodiments, the sensor may be coupled to the stent. Also disclosed are methods of delivery of the stent and the sensor to the eye.Type: ApplicationFiled: January 4, 2010Publication date: April 29, 2010Applicant: GLAUKOS CORPORATIONInventors: David S. Haffner, Hosheng Tu, Morteza Gharib
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Patent number: D645489Type: GrantFiled: December 22, 2009Date of Patent: September 20, 2011Assignee: Glaukos CorporationInventors: Henrick K. Gille, Ali Nikkhah
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Patent number: D645490Type: GrantFiled: December 22, 2009Date of Patent: September 20, 2011Assignee: Glaukos CorporationInventors: Henrick K. Gille, Ali Nikkhah