Patents Assigned to GPI
  • Pipecolic acid derivative hair growth compositions and uses
    Publication number: 20010036947
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using pipecolic acid derivatives.
    Type: Application
    Filed: February 13, 2001
    Publication date: November 1, 2001
    Applicant: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Novel pyrrolidine carboxylate hair revitalizing agents
    Publication number: 20010029263
    Abstract: This invention relates to methods of treating hair loss, through hair revitalization and germination, by administering non-immunosuppresive pyrrolidine carboxylate compounds.
    Type: Application
    Filed: April 5, 2001
    Publication date: October 11, 2001
    Applicant: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • N-linked sulfonamides of heterocyclic thioesters
    Patent number: 6294551
    Abstract: This invention relates to neurotrophic low molecular weight, small molecule N-linked sulfonamides of heterocyclic thioesters having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.
    Type: Grant
    Filed: March 1, 2000
    Date of Patent: September 25, 2001
    Assignee: GPI Nil Holdings, Inc.
    Inventors: Gregory S. Hamilton, Jai-He Li, Wei Huang
  • Small molecule inhibitors of rotamase enzyme activity
    Patent number: 6291510
    Abstract: This invention relates to neurotrophic compounds having an affinity for FKBP-type immunophilins, their preparation and use as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity.
    Type: Grant
    Filed: May 7, 1998
    Date of Patent: September 18, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Gregory S. Hamilton, Joseph P. Steiner
  • N-linked ureas and carbamates of heterocyclic thioesters
    Patent number: 6274607
    Abstract: This invention relates to neurotrophic low molecular weight, small molecule N-linked ureas and carbamates of heterocyclic thioesters having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.
    Type: Grant
    Filed: September 10, 1999
    Date of Patent: August 14, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Gregory S. Hamilton, Jia-He Li, Wei Huang
  • Heterocyclic ester and amide hair growth compositions and uses
    Patent number: 6274617
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using heterocyclic esters or amides.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: August 14, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Heterocyclic thioester and ketone hair growth compositions and uses
    Patent number: 6274602
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using heterocyclic thioesters and ketones.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: August 14, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • N-linked urea or carbamate of heterocyclic thioester hair growth compositions and uses
    Patent number: 6271244
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using N-linked ureas or carbamates of heterocyclic thioesters.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: August 7, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • N-oxides of heterocyclic esters, amides, thioesters, and ketones
    Patent number: 6251892
    Abstract: This invention relates to neurotrophic low molecular weight, small molecule N-oxides of heterocyclic esters, amides, thioesters, and ketones having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.
    Type: Grant
    Filed: April 21, 2000
    Date of Patent: June 26, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Gregory S. Hamilton, Joseph P. Steiner, Eric S. Burak
  • Method of using neurotrophic sulfonamide compounds
    Patent number: 6245783
    Abstract: This invention relates to a method of using neurotrophic low molecular weight, small molecule sulfonamide compounds having an affinity for FKBP-type immunophilins, as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.
    Type: Grant
    Filed: October 18, 1999
    Date of Patent: June 12, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Gregory S. Hamilton, Jia-He Li, Joseph P. Steiner
  • Pyrrolidine carboxylate and pyrrolidine amide hair revitalizing agents
    Patent number: 6239164
    Abstract: This invention relates to methods of treating hair loss, through hair revitalization and germination, by administering non-immunosuppresive pyrrolidine carboxylate and pyrrolidine amide compounds.
    Type: Grant
    Filed: August 9, 1999
    Date of Patent: May 29, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Pyrrolidine derivatives for vision and memory disorders
    Patent number: 6218423
    Abstract: This invention relates to pharmaceutical compositions and methods for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance using pyrrolidine derivatives.
    Type: Grant
    Filed: August 14, 1998
    Date of Patent: April 17, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Douglas T. Ross, Hansjörg Sauer, Gregory S. Hamilton, Joseph P. Steiner
  • Heterocyclic ketone and thioester compounds and uses
    Patent number: 6218424
    Abstract: This invention relates to neurotrophic, low molecular weight, small molecule heterocyclic ketone and thioester compounds, compositions containing the same, and the use of such compounds for treating neurological disorders, including physically damaged nerves and neurodegenerative diseases.
    Type: Grant
    Filed: November 22, 1999
    Date of Patent: April 17, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Gregory S. Hamilton, Jia-He Li
  • Heterocyclic esters and amides
    Patent number: 6218544
    Abstract: This invention relates to neurotrophic low molecular weight, small molecule heterocyclic esters and amides having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.
    Type: Grant
    Filed: November 18, 1999
    Date of Patent: April 17, 2001
    Assignee: Gpi Nil Holdings, Inc.
    Inventors: Jia-He Li, Gregory S. Hamilton
  • Heterocyclic esters and amides
    Patent number: 6200972
    Abstract: This invention relates to neurotrophic low molecular weight, small molecule heterocyclic esters and amides having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.
    Type: Grant
    Filed: February 23, 1998
    Date of Patent: March 13, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Jia-He Li, Gregory S. Hamilton
  • Small molecule carbamate or urea hair growth compositions and uses
    Patent number: 6194440
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using small molecule carbamates and ureas.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: February 27, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Small molecule pipecolic acid derivative hair growth compositions and uses
    Patent number: 6191125
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using pipecolic acid derivatives.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: February 20, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • N-linked sulfone of heterocyclic thioester hair growth compositions and uses
    Patent number: 6187806
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using N-linked sulfonamides of heterocyclic thioesters.
    Type: Grant
    Filed: July 23, 1999
    Date of Patent: February 13, 2001
    Assignee: GPI NIL Holdings
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Pipecolic acid derivative hair growth compositions and uses
    Patent number: 6187784
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using pipecolic acid derivatives.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: February 13, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Sulfone hair growth compositions and uses
    Patent number: 6187796
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using small molecule sulfonamides.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: February 13, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton