Patents Assigned to GUANGXI UNIVERSITY
  • Publication number: 20240099311
    Abstract: A virulence factor FsPL gene from the sugarcane pokkah boeng disease and use thereof are provided. The virulence factor FsPL gene from the sugarcane pokkah boeng disease has a sequence set forth in SEQ ID NO: 1. The present invention reveals a gene FsPL that is related to the pathogenicity of F. sacchari. Preliminary analysis shows that the deletion of the gene affects the ability of hyphae to penetrate and further affects the pathogenicity of pathogens. This provides a basis for the molecular mechanism of the pathogen infection and pathogenic process.
    Type: Application
    Filed: March 16, 2023
    Publication date: March 28, 2024
    Applicant: GUANGXI UNIVERSITY
    Inventors: Zhenzhen DUAN, Wei YAO, Muqing ZHANG, Caixia WANG, Zhen HUANG, Yixue BAO, Huixue LI
  • Publication number: 20240034991
    Abstract: In a method for efficiently inducing reprogramming of human cells into neuronal cells, a concentration of cAMP is increased or an expression of PKA and CREB is up-regulated or an expression of AMPK, ALK2, ALK3, P38, and JNK is inhibited by a single small molecule compound or gene knockout or gene overexpression. In the present disclosure, the induction small molecule compound is single and safe, and has a short induction time, high induction efficiency, definite induction sites and genes, and clear molecular regulation mechanism. The small molecule compound can be applied to the clinical treatment of human neurodegenerative diseases, providing a safer and more efficient treatment method for the neurodegenerative diseases. Since neuronal cells cannot divide and proliferate, the method induces fibroblasts and astrocytes that can divide and proliferate in vitro and in vivo, to continuously obtain a large number of induced neuronal cells in vitro and in vivo.
    Type: Application
    Filed: July 27, 2022
    Publication date: February 1, 2024
    Applicants: GUANGXI UNIVERSITY, Guangxi Benpeng Biotechnology Co., Ltd.
    Inventors: Ben HUANG, Guodong WANG, Dandan ZHANG, Quanhui LIU, Yulian WU, Danwei LV, Jigang HU, Xiaolian XIE
  • Patent number: 11825844
    Abstract: The present disclosure provides a method for controlling Fusarium oxysporum f. sp. cubense tropical race 4 (Foc TR4). The present disclosure mainly aims to solve the problem of effectively inhibiting the Foc TR4, but the existing fungicides cannot effectively inhibit the Foc TR4 without damage to banana plants. By treating with the fungicide disclosed by the present disclosure, the growth of the Foc TR4 can be limited, and there is no adverse effect on banana plants.
    Type: Grant
    Filed: June 1, 2022
    Date of Patent: November 28, 2023
    Assignee: GUANGXI UNIVERSITY
    Inventors: Jianxiong Li, Zhihong Tian, Zhiyan Zhu
  • Patent number: 11738329
    Abstract: The present invention provides a bionic fiber adsorptive material with multi-adsorption sites and a preparation method and use thereof, and the material is rich in multi-adsorption sites (N, O and S). The material is obtained by blending three polyethyleneimine polymers modified by multifunctional groups respectively with a carboxylated nanocellulose and graphene oxide, then adopting a coaxial spinning method based on a principle of imitating spider spinning, and then adopting a post-crosslinking technology. The material has a multilayer structure with the nanocellulose as a skeleton, the graphene oxide as an outer layer, and the three polyethyleneimine polymers modified by the multifunctional groups respectively as an inner layer, and a connection among the layers is a chemical bond connection. Densities of N, O and S adsorption sites of the material according to the present invention are all higher than 5 mmol/g.
    Type: Grant
    Filed: March 29, 2021
    Date of Patent: August 29, 2023
    Assignee: GUANGXI UNIVERSITY
    Inventors: Hongxiang Zhu, Hui He, Lei Wang, Shuangfei Wang, Hang Zhou
  • Patent number: 11731997
    Abstract: The disclosure provides a method for preparing an amphiphilic lignin nanomaterial based on pulping black liquor, an amphiphilic lignin nanomaterial, and an oil sludge detergent. In the disclosure, physical treatments such as ball milling and high-pressure jet homogenization treatment are conducted on alkali lignin at the early stage to adjust the molecular weight and size of alkali lignin and thus to give alkali lignin nanoparticles with uniform particle sizes; and on this basis, a chemical treatment such as alkylation grafting modification is conducted to give amphiphilic lignin nanoparticles with both hydrophilicity and lipophilicity. Due to the nano-size effect, the amphiphilic lignin nanomaterial has a significantly-increased specific surface area (SSA) and effectively-improved surface properties, which can reduce the oil-water interfacial tension, and emulsify the crude oil and peel off the crude oil from the surface of rock particles, so as to achieve the purpose of oil-solid separation.
    Type: Grant
    Filed: November 11, 2020
    Date of Patent: August 22, 2023
    Assignee: GUANGXI UNIVERSITY
    Inventors: Chengrong Qin, Jian Zhang, Chen Liang, Shuangquan Yao, Xinliang Liu, Zhiwei Wang, Wei Li, Jiulong Sha
  • Patent number: 11731104
    Abstract: The invention provides a biomass-based hyperbranched adsorption material with multi-adsorption sites to multiple heavy metal ions and a preparation method thereof. The biomass-based hyperbranched adsorption material with multi-adsorption sites to multiple heavy metal ions is prepared by one-step instant-crosslinking method using a biomass raw material as matrix and a hyperbranched polymer containing chelating atoms of N, O, and S as functional reagent, wherein the hyperbranched polymer has two or more different adsorption sites (containing elements such as N, S, O, etc.) to heavy metal ions.
    Type: Grant
    Filed: August 12, 2021
    Date of Patent: August 22, 2023
    Assignee: GUANGXI UNIVERSITY
    Inventors: Hongxiang Zhu, Hui He, Lei Wang, Fei Xue, Xianlin Lei
  • Patent number: 11733212
    Abstract: A method for quantitative analysis of a cavity at the top of a concrete-filled steel tube is disclosed. By substitution of the determined inner radius of the steel tube, the thickness of the steel tube wall and the propagation speed of ultrasonic waves in the steel tube and in the concrete, the propagation time of the ultrasonic wave between the top and the bottom of the concrete-filled steel tube enables calculation of the height of the cavity. The method can be used to quantify the cavity height at the top of the concrete-filled steel tube, with small relative errors and high accuracy.
    Type: Grant
    Filed: March 25, 2021
    Date of Patent: August 22, 2023
    Assignee: Guangxi University
    Inventors: Zheng Chen, Jielian Zheng, Zengxin Ye, Jiaping Liu, Jianjun Wang, Changjie Wu, Wen Xu, Weiwei Xie
  • Patent number: 11630097
    Abstract: The present invention relates to a quantitative evaluation method for concrete workability based on bottom resistance, including the following steps: step 1, carrying out a test for bottom resistance of fresh concrete; step 2, drawing a curve of inserting velocity of steel sheet over time; and step 3, quantitatively evaluating a concrete workability based on conditions of the bottom resistance. This method can quantitatively characterize the sinking condition of aggregate of the fresh concrete by effectively carrying out the test for bottom resistance of fresh concrete, calculating the inserting velocity of concrete and drawing the curves of displacement and velocity over time, so as to achieve the quantitative evaluation for concrete workability and overcome the defects of conventional methods that it is difficult to quantitatively characterize the segregation degree of concrete.
    Type: Grant
    Filed: December 28, 2020
    Date of Patent: April 18, 2023
    Assignee: GUANGXI UNIVERSITY
    Inventors: Zheng Chen, Ben Chen, Changjie Wu, Zhongxing Zou, Xin Sun
  • Publication number: 20230066648
    Abstract: The present disclosure provides a method for inducing transdifferentiation of somatic cells into mammary epithelial cells in vitro using a small molecule compound. The method includes: inhibiting an expression of TGFbeta R1 and related sites thereof, to induce the transdifferentiation of the somatic cells into the mammary epithelial cells in vitro. The present disclosure fills a gap in the technology of inducing the transdifferentiation of fibroblasts to the mammary epithelial cells using the small molecule compound; the present disclosure also provides a research platform for in vitro researches on a mammary gland bioreactor, mammary gland development and differentiation, breast cancer, and transdifferentiation of the fibroblasts into other types of functional cells.
    Type: Application
    Filed: June 30, 2020
    Publication date: March 2, 2023
    Applicants: GUANGXI UNIVERSITY, Guangxi Benpeng Biotechnology Co., Ltd.
    Inventors: Ben HUANG, Dandan ZHANG, Sheng YE, Shaoqian ZHU, Quanhui LIU, Liangshan QIN, Deshun SHI, Jigang HU, Xiaolian XIE
  • Publication number: 20220395808
    Abstract: The invention provides a biomass-based hyperbranched adsorption material with multi-adsorption sites to multiple heavy metal ions and a preparation method thereof. The biomass-based hyperbranched adsorption material with multi-adsorption sites to multiple heavy metal ions is prepared by one-step instant-crosslinking method using a biomass raw material as matrix and a hyperbranched polymer containing chelating atoms of N, O, and S as functional reagent, wherein the hyperbranched polymer has two or more different adsorption sites (containing elements such as N, S, O, etc.) to heavy metal ions.
    Type: Application
    Filed: August 12, 2021
    Publication date: December 15, 2022
    Applicant: GUANGXI UNIVERSITY
    Inventors: Hongxiang ZHU, Hui HE, Lei WANG, Fei XUE, Xianlin LEI
  • Publication number: 20220360079
    Abstract: Disclosed is an optimal power flow acquiring method for regional distribution network of small hydropower groups based on deep learning, which specifically includes the following steps: generating required data sets by adopting continuous power flow and power flow equation calculation methods; the data set is randomly divided into training data (80 percent) and test data (20 percent); training the built convolutional neural network model with training data to learn the mapping relationship between load and generator output power; inputting test data, and directly obtaining PG and QG from the trained convolutional neural network; and solving residual variables Vi and ?i with traditional power flow solver. The application can accelerate the solving speed of the optimal power flow problem with higher prediction accuracy.
    Type: Application
    Filed: April 24, 2022
    Publication date: November 10, 2022
    Applicant: GUANGXI UNIVERSITY
    Inventors: Xiaoqing BAI, Biyun CHEN, Yujing JIA, Bin LI, Peijie LI, Yun ZHU, Ge ZHANG, Yunyi LI, Tianyi DIAO, Guang LIU, Danlei CHEN, Shangfu WEI, Xian TANG, Liqin ZHENG, Xinwen WANG, Songyang ZHU, Zonglong WENG, Qinghua SHANG, Rui WANG, Puming WANG, Xiaoqing SHI
  • Publication number: 20220326213
    Abstract: The present invention relates to a quantitative evaluation method for concrete workability based on bottom resistance, including the following steps: step 1, carrying out a test for bottom resistance of fresh concrete; step 2, drawing a curve of inserting velocity of steel sheet over time; and step 3, quantitatively evaluating a concrete workability based on conditions of the bottom resistance. This method can quantitatively characterize the sinking condition of aggregate of the fresh concrete by effectively carrying out the test for bottom resistance of fresh concrete, calculating the inserting velocity of concrete and drawing the curves of displacement and velocity over time, so as to achieve the quantitative evaluation for concrete workability and overcome the defects of conventional methods that it is difficult to quantitatively characterize the segregation degree of concrete.
    Type: Application
    Filed: December 28, 2020
    Publication date: October 13, 2022
    Applicant: GUANGXI UNIVERSITY
    Inventors: Zheng CHEN, Ben CHEN, Changjie WU, Zhongxing ZOU, Xin SUN
  • Patent number: 11466406
    Abstract: A cellulose-silicon oxide composite superhydrophobic material and a preparation method thereof are disclosed. In the method, cellulose substrates with different surface topographies are pretreated by a low-temperature plasma, and then a first silicon oxide layer is deposited on the cellulose substrate by a low-temperature plasma-enhanced chemical vapor deposition method, then modified by a low-temperature plasma, and finally a second silicon oxide layer is deposited thereon, thereby preparing a micro-nano structured superhydrophobic surface on the cellulose substrate, to obtain a cellulose-silicon oxide composite superhydrophobic material, which is an environmentally friendly bio-based hydrophobic material.
    Type: Grant
    Filed: December 9, 2020
    Date of Patent: October 11, 2022
    Assignee: GUANGXI UNIVERSITY
    Inventors: Chongxing Huang, Yuan Zhao, Hui Zhao, Lijie Huang, Yangfan Xu, Qingshan Duan, Cuicui Li, Hongxia Su, Jian Wang, Linyun Zhang
  • Patent number: 11434306
    Abstract: The present disclosure provides a low-molecular-weight Tremella aurantialba glucuronoxylomannan (LTAG) as well as a preparation method and an application thereof, and specifically relates to the technical field of medicine. The LTAG provided in the present disclosure has a weight-average molecular weight of 8,000-24,000 Da. In the method of preparing LTAG as provided in the present disclosure, Tremella aurantialba glucuronoxylomannan is depolymerized by peroxides so as to get low-molecular-weight products, which are then exchanged into pharmaceutically acceptable salts through cation exchange resins. The resulting LTAG has a clear structure, a low viscosity and a good solubility, has a strong immune-enhancing activity, and is capable of acting on TLR4 receptor-activated macrophagocytes and promoting the production of various immune factors, so it can be used in the prevention and/or treatment of immunodeficiency-related diseases.
    Type: Grant
    Filed: January 6, 2021
    Date of Patent: September 6, 2022
    Assignee: GUANGXI UNIVERSITY OF CHINESE MEDICINE
    Inventors: Qingxia Yuan, Longyan Zhao, Hong Li, Ziyi Wei
  • Publication number: 20220241752
    Abstract: The present invention provides a bionic fiber adsorptive material with multi-adsorption sites and a preparation method and use thereof, and the material is rich in multi-adsorption sites (N, O and S). The material is obtained by blending three polyethyleneimine polymers modified by multifunctional groups respectively with a carboxylated nanocellulose and graphene oxide, then adopting a coaxial spinning method based on a principle of imitating spider spinning, and then adopting a post-crosslinking technology. The material has a multilayer structure with the nanocellulose as a skeleton, the graphene oxide as an outer layer, and the three polyethyleneimine polymers modified by the multifunctional groups respectively as an inner layer, and a connection among the layers is a chemical bond connection. Densities of N, O and S adsorption sites of the material according to the present invention are all higher than 5 mmol/g.
    Type: Application
    Filed: March 29, 2021
    Publication date: August 4, 2022
    Applicant: GUANGXI UNIVERSITY
    Inventors: Hongxiang ZHU, Hui HE, Lei WANG, Shuangfei WANG, Hang ZHOU
  • Patent number: 11391560
    Abstract: An image acquisition device and a measuring method for geometric parameters of a specific developing area on a concrete test block. In the image acquisition device, a digital camera is provided on a camera support; the camera support is provided with a screw bearing which is connected to a first stepping motor via a first coupling; the camera support is provided on a screw slideway which is connected to a second stepping motor via a second coupling; the screw slideway, the first stepping motor and the second stepping motor are provided on a rear platform of a L-shaped base; a spirit level and a controller are respectively provided at two sides of the rear platform of the L-shaped base; and a reference glass plate is arranged on a front raised platform of the L-shaped base.
    Type: Grant
    Filed: May 7, 2020
    Date of Patent: July 19, 2022
    Assignee: GUANGXI UNIVERSITY
    Inventors: Lufeng Yang, Junwu Chen, Hao Kang, Xiani Liang, Zheng Chen, Jiaqi Zhao, Weizhe Sun, Wenting Nong, Weifu Lu, Linyu Gan
  • Patent number: 11263435
    Abstract: A method for recognizing a face from monitoring video data is disclosed. Two neural networks are used to compare and score high-dimensional face features of a face, and a K-neighbor algorithm and a screening mechanism with a Euclidean distance as a threshold are combined for face comparison recognition to obtain an accurate face recognition result. In addition, the present disclosure also performs further screening based on the time of video data and the frequency of face appearance, and finally obtains a recognition result, thereby obtaining a more accurate face recognition result. The present disclosure can perform relatively accurate face recognition on video data or picture data captured by a real-time or historical monitoring camera.
    Type: Grant
    Filed: July 29, 2020
    Date of Patent: March 1, 2022
    Assignee: Guangxi University
    Inventors: Zuojun Fan, Jian Gao, Wenjun Jiang, Guanglin Liang
  • Publication number: 20220041762
    Abstract: The present disclosure provides a low-molecular-weight Tremella aurantialba glucuronoxylomannan (LTAG) as well as a preparation method and an application thereof, and specifically relates to the technical field of medicine. The LTAG provided in the present disclosure has a weight-average molecular weight of 8,000-24,000 Da. In the method of preparing LTAG as provided in the present disclosure, Tremella aurantialba glucuronoxylomannan is depolymerized by peroxides so as to get low-molecular-weight products, which are then exchanged into pharmaceutically acceptable salts through cation exchange resins. The resulting LTAG has a clear structure, a low viscosity and a good solubility, has a strong immune-enhancing activity, and is capable of acting on TLR4 receptor-activated macrophagocytes and promoting the production of various immune factors, so it can be used in the prevention and/or treatment of immunodeficiency-related diseases.
    Type: Application
    Filed: January 6, 2021
    Publication date: February 10, 2022
    Applicant: GUANGXI UNIVERSITY OF CHINESE MEDICINE
    Inventors: Qingxia YUAN, Longyan ZHAO, Hong LI, Ziyi WEI
  • Patent number: 11185796
    Abstract: The present disclosure provides a fast and high-capacity intelligent cellulose-based oil-absorbing material and a preparation method and use thereof. The material includes an intelligent response layer and an adsorption layer. The intelligent response layer is a pH-responsive nanofiber layer with an adjustable pH response performance and is obtained by grafting hyperbranched polycarboxylic acid-modified polyethyleneimine on to carboxylated cellulose nanofibers. The hyperbranched polycarboxylic acid is prepared by melting and polycondensing at a high temperature, using trimethylolpropane as a core, citric acid as a reactive monomer, and p-toluenesulfonic acid as a catalyst. The adsorption layer is prepared by coating ferroferric oxide with the carboxylated cellulose nanofibers to prepare magnetic carboxylated cellulose nanofibers, and then modifying the magnetic carboxylated cellulose nanofibers with hexadecylamine.
    Type: Grant
    Filed: October 22, 2020
    Date of Patent: November 30, 2021
    Assignee: GUANGXI UNIVERSITY
    Inventors: Chengrong Qin, Hui He, Lei Wang, Hongxiang Zhu, Chao Zhao, Rimei Chen, Zongyan Quan, Zhiping Chen
  • Patent number: 11045788
    Abstract: The present invention discloses a near-infrared regenerative intelligent fiber-based adsorptive material and a preparation method and use thereof. The material is obtained by chemically grafting a stepwise dual-temperature stimuli-responsive polyethyleneimine onto a carboxylated cellulose nanofiber matrix to prepare a stepwise dual-temperature stimuli-responsive intelligent nanofiber, and combining the stepwise dual-temperature stimuli-responsive intelligent nanofiber with a photosensitizer having near-infrared stimuli-response to prepare a stepwise dual-temperature/near-infrared stimuli-responsive intelligent nanofiber, and then by using a crosslinking agent to directly crosslink and combine the stepwise dual-temperature/near-infrared stimuli-responsive intelligent nanofiber with a hyperbranched polyamine in one step. The material has a stepwise dual-temperature/near-infrared stimuli-response, high density of amino group (greater than 14 mmol/g), and nano cavities.
    Type: Grant
    Filed: June 11, 2020
    Date of Patent: June 29, 2021
    Assignee: GUANGXI UNIVERSITY
    Inventors: Hui He, Chengrong Qin, Shuangfei Wang, Rimei Chen, Xiaoyu Shi, Jiehan Lin, Chao Zhao, Qin Lu