Abstract: The present invention relates to a novel method of obtaining a factor involved in appetite control and/or body weight control, as well as genes obtained by said method, polypeptides encoded by said genes, or novel polypeptides obtained from the information on polypeptides encoded by said genes as a means for treating, controlling or diagnosing diseases associated with eating disorders and/or body weight control. Also the present invention relates to substances that inhibit the effects of said genes or said polypeptides as a means for treating, controlling or diagnosing diseases associated with appetite control and/or body weight control. By using thiazolidine diones having a PPAR ? agonist activity, genes and polypeptides involved in appetite regulation and/or body weight reduction can be obtained. NESFATIN or the like obtained by said method can be used as a means for treating, controlling or diagnosing diseases associated with eating disorders and/or body weight control.

Abstract: The compound represented by the general formula (I) is administered to a subject suffering from diabetes or obesity. In the formula (I), R1 and R2 independently represent an aliphatic hydrocarbon group having 1 to 10 carbon atoms or phenyl group, and arbitrary hydrogen atoms on the aliphatic hydrocarbon group and the phenyl group may be replaced by halogen, X1 represents halogen, and X2 represents hydrogen or halogen.

Abstract: A gaseous fuel injector 3 supplies gaseous fuel from a compressed gas cylinder 1 into a measuring portion thin tube 5 and pressure change in the tube is measured by a pressure measuring device 4 through a small hole provided in the thin tube 5. An extension thin tube 6 for removing the influence of reflected waves is provided on the downstream side of the measuring portion thin tube 5. There is provided at the downstream side end of the extension thin tube a back pressure valve 13 for uniformly increasing the pressure in the tube and for bringing the pressure close to the actual environment in the engine cylinder. Also, a tapered-shape nozzle is arranged in the measuring portion thin tube 5. Pressure measured by the pressure measuring device 4 is transduced into mass flow rate in the thin tube according to a predetermined calculation formula. Accordingly, it is possible to measure instantaneous mass flow rate of gaseous fuel injected from the gaseous fuel injector.

Abstract: A table forming unit calculates, in a weighted reproducing kernel Hilbert space formed of an absolutely continuous function that is zero at an origin, solutions of simultaneous equations obtained by discretization of an integral equation of the second kind derived from Tikhonov regularization method with a weighted square integrable space used as an observation space, and forms an H table describing information including numerical solution of the integral equation of the second kind based on the solutions of the simultaneous equations. An inverse transform unit obtains, by numerical calculation, an inner product, in the weighted square integrable space, of the numerical solution of the integral equation of the second kind and a Laplace transform image multiplied by a mollifier function with reference to the H table.

Abstract: The present invention relates to a novel method of obtaining a factor involved in appetite control and/or body weight control, as well as genes obtained by said method, polypeptides encoded by said genes, or novel polypeptides obtained from the information on polypeptides encoded by said genes as a means for treating, controlling or diagnosing diseases associated with eating disorders and/or body weight control. Also the present invention relates to substances that inhibit the effects of said genes or said polypeptides as a means for treating, controlling or diagnosing diseases associated with appetite control and/or body weight control. By using thiazolidine diones having a PPAR ? agonist activity, genes and polypeptides involved in appetite regulation and/or body weight reduction can be obtained. NESFATIN or the like obtained by said method can be used as a means for treating, controlling or diagnosing diseases associated with eating disorders and/or body weight control.

Abstract: A cantilever type sensor includes a cantilever, an actuator that oscillates the cantilever, and a sensor provided at the cantilever so as to detect an oscillation condition of the cantilever. Further, the cantilever type sensor includes a control unit that controls the actuator so as to cause the cantilever to be subjected to pulse excitation, and a measurement unit that measures a physical quantity related to a measurement object, based on a change in pulse response detected in the sensor.

Abstract: A carbon nanomaterial produced by: performing centrifugal melt spinning of core-shell particles that are prepared by using fine particles containing a carbon precursor polymer and a thermally decomposable polymer that disappears as a result of heat treatment, wherein the core-shell particles are heated up to a temperature at which phase separation thereof is not caused, and pressed against a plate-like heater 12 having a large number of pores 12A that penetrate therethrough in a thickness direction of the plate-like heater using centrifugal force; making the fiber obtained by the centrifugal melt spinning infusible; and performing carbonization thereof. According to this method, a carbon nanomaterial such as a carbon nanotube or a carbon nanofiber can be produced with high efficiency.

Abstract: A subject is imaged for treatment of the subject such as an eye to be inspected, while irradiating a charged particle beam on the eye, so that an aim position of a charged particle beam for treatment can be determined.

Abstract: In a schlieren optical system, a laser beam is passed through the jet flow and the ambient around the jet flow, and a high speed sampling is performed using a high speed photo sensor while displacing measurement points. The value obtained by sampling represents a result of the optical path caused curved by a density gradient generated in an arc-shape from the center of the jet flow. The value is subjected to a high speed discrete Fourier transform and decomposed into frequency components which constitute the noise. Thereafter, Abel inversion is performed on data belonging to a particular frequency to obtain a density gradient in the radial direction from the center of the jet flow. The obtained density gradient is visualized in a graph display, so that the position of the sound source and the state of the jet flow can be accurately grasped.

Abstract: The peptide production method of the present invention produces a peptide (SEQ ID NO: 1) of a protein from Plasmodium falciparum, which is effective as a malaria vaccine. The method produces the peptide of SEQ ID NO: 1 by linking the fragments (i) through (v) shown below: (v) Asn-Asn-Asp-Xaa (SEQ ID NO: 2); (iv) Asp-Phe-Lys-Thr-Pro (SEQ ID NO: 3); (iii) Asn-Lys-Thr-Tyr-Asp-Leu (SEQ ID NO: 4); (ii) Phe-Tyr-Asn-Ser-Glu (SEQ ID NO: 5); and (i) Xaa-Ala-Ser-Glu (SEQ ID NO: 6), where ‘Xaa’ in (i) and (v) represents zero or any arbitrary number of amino acid residues.

Abstract: Minute masses of a plurality of measuring objects are measured at a time. A multi-lever is prepared, in which a plurality of cantilevers, each having a buried piezoresistance element, is provided. Different measuring object attracting substances are coated on the multi-lever. The multi-lever is driven by a single vibration exciting device. The vibrational frequency is swept within a predetermined range, and the resonance frequency of each cantilever is detected. Frequency changes before putting in and after putting in the measuring object are detected, and based on this, the mass changes are calculated.

Abstract: Disclosed are a compound represented by the general formula (I) below and a polymer compound obtained by polymerizing such a compound. R1-Gly-Lac-Pro-R2 (I) (In the formula, -Gly-Lac-Pro- represents a glycine residue represented by the formula (II) below, a lactic acid residue and a tridepsipeptide linked with a proline residue; R1 represents an amino acid, polypeptide or hydroxycarboxylic acid linked by an amide bond; and R2 represents an amino acid or polypeptide linked by an amide bond, or a hydroxycarboxylic acid linked by an ester bond.

Abstract: A compound represented by the formula (I) is used as an active ingredient in a medicament for treatment or prevention of infectious diseases caused by protozoa or bacterium. X represents halogen, Z represents —(CH2)m— wherein m is an integer of 1-5, and R represents one of the following (i)-(v): (i) hydrogen n represents an integer of 0-5, R1's independently represent hydrogen, halogen, alkoxy having 1-5 carbon atoms or alkyl having 1-5 carbon atoms. R2's independently represent hydrogen, halogen, alkoxy having 1-5 carbon atoms or alkyl having 1-5 carbon atoms. (iv) alkyl having 1-5 carbon atoms, (v) hydroxyalkyl having 1-5 carbon atoms.

Abstract: A region-in object measuring system comprises a reference object (1) having two frames, i.e., an object surface frame (2) brought into contact with the surface of an object and a film frame (3) with which an X-ray film (7) is brought into contact, spaced from each other and a computing device.

Abstract: The invention provides a cancer chemotherapeutic agent which has fewer side effects and excellent efficacy. The cancer chemotherapeutic agent of the invention includes a cholestanol derivative represented by formula (1): (wherein G represents GlcNAc-Gal-, GlcNAc-Gal-Glc-, Fuc-Gal-, Gal-Glc-, Gal-, or GlcNAc-) or a cyclodextrin inclusion compound thereof, and an anti-cancer agent.

Abstract: A composite material is provided which is lightweight, mechanically strong, and excellent in formability and water resistance, and is capable of reducing an environmental burden. A production method of the composite material composed of a natural vegetable fiber and a synthetic polymer includes chemically bonding a molecular chain of the synthetic polymer to a surface of the natural vegetable fiber; kneading the chemically bonded fiber and a synthetic polymer of a type one of identical to and different from the synthetic polymer used in the chemical bonding; and forming the obtained kneaded material into a predetermined shape.

Abstract: A peptide having a sequence which satisfies all of the following requirements (I) to (V) and has an activity of stimulating an immune cell: (I) the number of constituent amino acid residues is 12 to 36; (II) the sequence is amphipathic; (III) the charge of the whole molecule is +2 or more; (IV) when constituent amino acid residues are arranged so as to form an a-helical structure, a side chain of any aromatic amino acid residue is not located between side chains of at least two positively charged amino acid residues on a side where hydrophilic amino acid residues are located; and (V) the sequence contains an amino acid residue which serves as a cleavage point for a mitochondrial processing enzyme.

Abstract: A water-insoluble liquid crystalline gel composed mainly of a water-soluble polymer, itself having a gelation function together with a liquid crystal formation function and having an optical property is produced. First, the water-soluble polymer is dissolved in water or an aqueous solution containing a salt(s) to prepare a polymer solution. Subsequently, this polymer solution is dialyzed in an aqueous solution containing a chemical crosslinking agent, thereby obtaining the gel having a liquid crystal structure and composed mainly of the water-soluble polymer. Said water soluble polymer is one or two or more polymers selected from the group consisting of water-soluble biopolymers, derivatives of these water-soluble biopolymers and water-soluble synthesized polymers. The water-soluble biopolymers are one or two or more polymers selected from the group consisting of nucleic acids, polysaccharides, proteins, modified proteins and polyamino acids.

Abstract: A high-precision ?? modulator reduces nonlinear noise due to the use of a multibit DAC and has little hardware and power consumption. A digital signal is DA converted and fed back to a subtraction circuit supplied with an analog signal. The DAC used in this feedback circuit uses a DAC (DWADAC) that includes a weighted pointer so that input digital signals are supplied in order to a plurality of segment elements that construct the DAC. In this DWADAC, the construction and number of the pointer is set based on the type and order of the filter disposed before the ADC.

Abstract: A plurality of data of still image for screening and zooming shot at maximum magnification to perform magnified observation with regard to a plurality of divided areas obtained by dividing a shoot target area in a microscopic image such that a portion of a peripheral portion of each of the dividing areas is overlapped to each other, and a plurality of data of still image for focusing shot by respectively shifting focus in each of the divided areas, are created. From data of tiled still image for screening and zooming and data of edited still images for focusing, which are obtained by applying a predetermined processing to the data of still image, an animated image for screening, an animated image for zooming, and an animated image for focusing are created, and an animated image reproducing motion of a microscopic image in actual microscope observation is displayed on a computer screen.