Patents Assigned to Gunma University
  • Patent number: 10406629
    Abstract: To provide a method for joining metal members, in which joining can be performed at relatively lower temperature, and deformation caused when joining the metal members can be reduced. The present invention includes a step of joining a plurality of metal members with a sheet sandwiched between the joining surfaces of the plurality of metal members, wherein the sheet is obtained by forming an organic acid metal salt film on the surface of a metal sheet; wherein aluminum or an aluminum alloy is used as the metal members, and a sheet made of any one of zinc, copper and magnesium is used as the metal sheet.
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: September 10, 2019
    Assignee: NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY
    Inventors: Shinji Koyama, Xiaojuan Ma, Tatsunori Tsunetou, Tsukasa Akiyama, Yohei Tomikawa
  • Patent number: 10392249
    Abstract: A hydrogen storage carbon material having a carbon structure suited for hydrogen storage and a production method thereof. The hydrogen storage carbon material according to this embodiment includes a carbon structure which has a ratio of an ultramicropore volume to a micropore volume of 60% or more, and in which stored hydrogen exhibits, in 1H-NMR measurement, a second peak at a position corresponding to a chemical shift of from ?2 ppm to ?20 ppm with respect to a first peak attributed to gaseous hydrogen.
    Type: Grant
    Filed: June 17, 2016
    Date of Patent: August 27, 2019
    Assignees: NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY, NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY, NISSHINBO HOLDINGS INC.
    Inventors: Haruo Kumagai, Jun-ichi Ozaki, Asao Oya, Takafumi Ishii, Takuya Maie, Rieko Kobayashi, Yasuo Imashiro
  • Patent number: 10385090
    Abstract: Disclosed is a nucleoside derivative of formulae (I-1) or a salt thereof: in which R1, R2, R3, R5, A1 to A3, B, X, Y, and k are described herein. Also provided are a 5?-phosphate ester and a 3?-phosphoramidite derivative of the nucleoside derivative and substrate solutions thereof. A polynucleotide is produced using the 5?-phosphate ester or 3?-phosphoramidite derivative of the nucleoside derivative. A library of the produced polynucleotide is used in a method of selecting a nucleic acid aptamer. Further provided is a vesicular endothelial growth factor binding agent of formula (i).
    Type: Grant
    Filed: September 10, 2014
    Date of Patent: August 20, 2019
    Assignee: NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY
    Inventor: Masayasu Kuwahara
  • Publication number: 20190248826
    Abstract: The present invention provides a novel nucleoside derivative or a salt thereof, a polynucleotide synthesis reagent, a method for producing a polynucleotide, a polynucleotide, and a method for producing a binding nucleic acid molecule. The nucleoside derivative or a salt thereof of the present invention is represented by the following chemical formula (1): where in the chemical formula (1), Su is an atomic group having a sugar skeleton at a nucleoside residue or an atomic group having a sugar phosphate skeleton at a nucleotide residue, and may or may not have a protecting group, L1 and L2 are each independently a straight-chain or branched, saturated or unsaturated hydrocarbon group having 2 to 10 carbon atoms, X1 and X2 are each independently an imino group (—NR1—), an ether group (—O—), or a thioether group (—S—), and the R1 is a hydrogen atom or a straight-chain or branched, saturated or unsaturated hydrocarbon group having 2 to 10 carbon atoms.
    Type: Application
    Filed: September 14, 2017
    Publication date: August 15, 2019
    Applicants: NEC Solution Innovators, Ltd., NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY
    Inventors: Hirotaka MINAGAWA, Katsunori HORII, Jou AKITOMI, Naoto KANEKO, Iwao WAGA, Masayasu KUWAHARA
  • Publication number: 20190241895
    Abstract: The present invention provides a novel molecule that can be used for detection of sIgA. The sIgA-binding nucleic acid molecule of the present invention is characterized in that it binds to secretory immunoglobulin A (sIgA) with a dissociation constant of 37.7 nM or less, and preferably includes a polynucleotide consisting of any of base sequences of SEQ ID NOs: 1 to 12 or a partial sequence thereof, for example. According to the sIgA-binding nucleic acid molecule of the present invention, it is possible to detect sIgA in saliva.
    Type: Application
    Filed: April 20, 2017
    Publication date: August 8, 2019
    Applicants: NEC Solution Innovators, Ltd., NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY
    Inventors: Hirotaka MINAGAWA, Katsunori HORII, Jou AKITOMI, Naoto KANEKO, Iwao WAGA, Masayasu KUWAHARA
  • Publication number: 20190211048
    Abstract: The present invention provides a novel nucleoside derivative or a salt thereof, a polynucleotide synthesis reagent, a method for producing a polynucleotide, a polynucleotide, and a method for producing a binding nucleic acid molecule. The nucleoside derivative or a salt thereof of the present invention is represented by the following chemical formula (1): where in the chemical formula (1), Su is an atomic group having a sugar skeleton at a nucleoside residue or an atomic group having a sugar phosphate skeleton at a nucleotide residue, and may or may not have a protecting group, L1 and L2 are each independently a straight-chain or branched, saturated or unsaturated hydrocarbon group having 2 to 10 carbon atoms, X1 and X2 are each independently an imino group (—NR1—), an ether group (—O—), or a thioether group (—S—), and the R1 is a hydrogen atom or a straight-chain or branched, saturated or unsaturated hydrocarbon group having 2 to 10 carbon atoms.
    Type: Application
    Filed: September 14, 2017
    Publication date: July 11, 2019
    Applicants: NEC Solution Innovators, Ltd., NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY
    Inventors: Hirotaka MINAGAWA, Katsunori HORII, Jou AKITOMI, Naoto KANEKO, Iwao WAGA, Masayasu KUWAHARA
  • Publication number: 20190190034
    Abstract: A carbon catalyst, a battery electrode, and a battery, each exhibits excellent catalytic performance. A carbon catalyst contains two kinds of transition metals and has such a carbon structure that an interplanar spacing d002, which is determined from a Bragg angle of one of three diffraction peaks fbroad, fmiddle, and fnarrow obtained by separating a diffraction peak around a diffraction angle (2?) of 26° in an X-ray diffraction pattern of powder X-ray diffraction with a CuK? ray, the one diffraction peak being the diffraction peak fbroad, is 0.374 nm or more.
    Type: Application
    Filed: June 1, 2017
    Publication date: June 20, 2019
    Applicants: NISSHINBO HOLDINGS INC., NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY
    Inventors: Yoshikazu KOBAYASHI, Yuji KUBOTA, Jun-ichi OZAKI, Takafumi ISHII, Takuya MAIE
  • Patent number: 10294419
    Abstract: [Problem] To provide highly heat-resistant and radiation-resistant radiation measuring equipment. [Solution] Provided are a charged particle radiation measuring method and a charged particle radiation measuring device using a scintillator comprising a phosphor in which the main component is a SiAlON phosphor.
    Type: Grant
    Filed: August 25, 2016
    Date of Patent: May 21, 2019
    Assignees: Denka Company Limited, National University Corporation Gunma University, National Institutes For Quantum And Radiological Science And Technology
    Inventors: Wataru Kada, Kenta Miura, Osamu Hanaizumi, Tomihiro Kamiya, Takahiro Satoh, Junichi Susaki, Suzuya Yamada
  • Patent number: 10232355
    Abstract: The present invention applies carbon nanotubes to catalyst particles, thereby providing catalyst particles which are usable in fluidized bed reactions, have high catalytic activity, and are easy to handle. The catalyst particles are carbon nanotube-coated catalyst particles which each comprise a carrier particle and a coating layer disposed on the surface of the carrier particle, wherein the carrier particles are flowable in fluidized beds and the coating layer comprises carbon nanotubes which have metal nanoparticles supported thereon and/or which have been doped with nitrogen or boron. The carbon nanotube-coated catalyst particles are flowable in fluidized bed reactions.
    Type: Grant
    Filed: March 1, 2016
    Date of Patent: March 19, 2019
    Assignee: NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY
    Inventors: Reiji Noda, Ryosuke Atsumi, Kyoya Wanibuchi
  • Patent number: 10199561
    Abstract: An electroconductive film for an actuator is formed from a gel composition including carbon nanofibers, an ionic liquid, and a polymer. The carbon nanofibers are produced with an aromatic mesophase pitch by melt spinning.
    Type: Grant
    Filed: March 22, 2016
    Date of Patent: February 5, 2019
    Assignees: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY, ALPS ELECTRIC CO., LTD.
    Inventors: Kinji Asaka, Takushi Sugino, Soshi Shiraishi, Isao Takahashi, Tomomasa Takatsuka, Shinya Komura
  • Patent number: 10179248
    Abstract: Provided is an implantable spacer that can be placed in a body and can be easily removed after placement. The implantable spacer includes a tube which is folded or bent at one or a plurality of positions to form partial sections adjacent to each other; fixing threads which are disposed along a direction transverse to the partial sections in order to maintain the shape of the tube; and a trigger thread for catching the fixing threads being in a releasable state.
    Type: Grant
    Filed: December 25, 2014
    Date of Patent: January 15, 2019
    Assignee: National University Corporation Gunma University
    Inventor: Takayuki Asao
  • Publication number: 20180346932
    Abstract: A DNA methylation editing kit comprises: (1) a fusion protein of inactivated CRISPR-associated endonuclease Cas9 (dCas9) having no nuclease activity and a tag peptide array in which plural tag peptides are linked by linkers, or an RNA or DNA coding therefor; (2) a fusion protein(s) of a tag peptide-binding portion and a methylase or demethylase, or an RNA(s) or DNA(s) coding therefor; and (3) a guide RNA(s) (gRNA(s)) comprising a sequence complementary to a DNA sequence within 1 kb of a desired site of methylation or demethylation, or a DNA(s) expressing the gRNA(s).
    Type: Application
    Filed: November 25, 2016
    Publication date: December 6, 2018
    Applicant: NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY
    Inventors: Izuho HATADA, Sumiyo MORITA, Takuro HORII
  • Publication number: 20180327746
    Abstract: The present invention provides a novel nucleic acid molecule that can be used for detection of ?-amylase. The ?-amylase-binding nucleic acid molecule of the present invention is characterized in that it binds to ?-amylase with a dissociation constant of 17 nM or less, and preferably includes a polynucleotide consisting of any of base sequences of SEQ ID NOs: 1 to 22, for example. According to the nucleic acid molecule of the present invention, it is possible to detect ?-amylase in saliva.
    Type: Application
    Filed: September 12, 2016
    Publication date: November 15, 2018
    Applicants: NEC Solution Innovators, Ltd., Gunma University
    Inventors: Hirotaka MINAGAWA, Katsunori HORII, Jou AKITOMI, Naoto KANEKO, Ikuo SHIRATORI, Iwao WAGA, Masayasu KUWAHARA
  • Patent number: 10099419
    Abstract: Disclosed is a polyethylene porous film having an average pore diameter of 200 nm or less, a specific surface area of 50 m2/g or more, and a porosity of 15% or more, each of which is measured by a mercury intrusion method at room temperature, the polyethylene porous film being obtained by forming pores only by drawing a film containing an ultrahigh molecular weight polyethylene having a viscosity average molecular weight of from 1 million to 15 million and a polyethylene having a weight average molecular weight of from 10,000 to 800,000 at a mass ratio of from 50:50 to 99:1. The polyethylene porous film is produced by molding a film using a mixture of the ultrahigh weight polyethylene and the polyethylene having a weight average molecular weight of from 10,000 to 800,000, biaxially drawing the film, then heat-treating and redrawing the film to form pores in the film.
    Type: Grant
    Filed: August 16, 2013
    Date of Patent: October 16, 2018
    Assignee: National University Corporation Gunma University
    Inventors: Hiroki Uehara, Takeshi Yamanobe, Hidekazu Tanaka
  • Publication number: 20180282156
    Abstract: A carbon material that is compact and exhibits an excellent hydrogen storage capacity. A carbon material has a specific surface area of 200 m2/g or less and exhibits a hydrogen storage capacity of 1.5×10?5 g/m2 or more at a hydrogen pressure of 10 MPa.
    Type: Application
    Filed: November 30, 2015
    Publication date: October 4, 2018
    Applicants: NISSHINBO HOLDINGS INC., NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY
    Inventors: Yasuo IMASHIRO, Rieko KOBAYASHI, Noriko OSUGA, Jun-ichi OZAKI, Hirotaka KUJIRAI, Setsura KOBAYASHI
  • Publication number: 20180280484
    Abstract: An effective amount of botulinum toxin type B is administered to a subject in need thereof for treating Raynaud's phenomenon. Botulinum toxin type B may be in a form of an injection, and may be locally administered to a disease affected site, in a dose of 200 to 400 units per disease affected site.
    Type: Application
    Filed: March 30, 2018
    Publication date: October 4, 2018
    Applicant: NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY
    Inventor: Sei-ichiro MOTEGI
  • Patent number: 10083800
    Abstract: First, the present invention involves adding a curing catalyst to a phenolic resin, polyvinyl alcohol, a pore-forming agent, and a cross-linking agent, and mixing, casting, heating, and drying the same. Next, the plate-shaped porous phenolic resin obtained thereby which has uniform consecutive macropores having an average pore diameter in the range of 3 to 35 ?m and formed in a three-dimensional network pattern is immersed with an organic solvent. Thereafter, this block is extracted and pressure is applied thereto. It is possible to obtain plate-shaped activated carbon for use in an electrode of a power-storage device by carbonizing and activating a block which has undergone this procedure by keeping the same at an increased temperature.
    Type: Grant
    Filed: September 3, 2014
    Date of Patent: September 25, 2018
    Assignees: AION CO., LTD., NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY
    Inventors: Hidehiko Tsukada, Kimiyasu Onda, Hiroshi Miyaji, Soshi Shiraishi, Yukiko Endo
  • Publication number: 20180266876
    Abstract: A system for detecting vibrations from a surface is provided. The system includes a coherent light source for projecting a multi-beam pattern onto the surface and an imaging device for mapping a speckle field generated by each spot formed on the surface by the multi-beam pattern to a unique region of an imaging sensor. The system further includes a processor for processing speckle field information received by the imaging sensor and deriving surface vibration information.
    Type: Application
    Filed: December 27, 2015
    Publication date: September 20, 2018
    Applicant: National University Corporattion Gunma University
    Inventor: Gideon CARMON
  • Publication number: 20180264587
    Abstract: To provide a method for joining metal members, in which joining can be performed at relatively lower temperature, and deformation caused when joining the metal members can be reduced. The present invention includes a step of joining a plurality of metal members with a sheet sandwiched between the joining surfaces of the plurality of metal members, wherein the sheet is obtained by forming an organic acid metal salt film on the surface of a metal sheet; wherein aluminum or an aluminum alloy is used as the metal members, and a sheet made of any one of zinc, copper and magnesium is used as the metal sheet.
    Type: Application
    Filed: December 21, 2015
    Publication date: September 20, 2018
    Applicant: National University Corporation Gunma University
    Inventors: Shinji KOYAMA, Xiaojuan MA, Tatsunori TSUNETOU, Tsukasa AKIYAMA, Yohei TOMIKAWA
  • Patent number: 10049824
    Abstract: An activated carbon for an electrode of a power storage device of the present invention has uniform consecutive macropores, and a pore size distribution centered within a range of 1.5 to 25 ?m, a specific surface area within a range of 1,500 to 2,300 m2/g, a micropore volume within a range of 0.4 to 1.0 mL/g, and an average micropore width within a range of 0.7 to 1.2 nm. Provided is an activated carbon for an electrode of a power storage device suitable for an electric double layer capacitor that has high capacitance during charging and discharging at high current density and excellent endurance against charging at a high voltage of 3 V or more and a lithium-ion capacitor having excellent endurance against charging at a high voltage of 4 V or more.
    Type: Grant
    Filed: February 22, 2013
    Date of Patent: August 14, 2018
    Assignees: AION CO., LTD, NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY
    Inventors: Hidehiko Tsukada, Kimiyasu Onda, Hiroshi Miyaji, Soshi Shiraishi, Yukiko Endo