Patents Assigned to Haemonetics Corporation
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Patent number: 11135349Abstract: A tubing set for a blood processing system includes a first connector, a first tube, and a second tube. The first connector is configured to connect to a separation device within the blood processing system, and has a first inlet configured to be fluidly connected to an outlet of the separation device. The first connector also has an outlet and a second inlet. The first tube fluidly connects to the outlet and fluidly connects the separation device and a blood component storage container. The second tube is fluidly connected to the second inlet and fluidly connects the separation device and a saline storage container. The second tube may include a second connector that connects to the saline storage container.Type: GrantFiled: June 14, 2017Date of Patent: October 5, 2021Assignee: Haemonetics CorporationInventor: Christopher S. McDowell
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Patent number: 11065376Abstract: A plasmapheresis bowl for the separation and collection of plasma includes a core and a feed tube that increase the bowl efficiency and reduce foaming within the plasma. The core may have a cylindrical body and a ledge located within the interior of the core. The ledge extends radially inward from the core and defines, at least partially, a collection chamber within the plasmapheresis bowl. The core also has ribs that extend above the top of core body and create flow paths that allow fluid to enter the interior of the cylindrical body and collection chamber. The feed tube has a flow path extending through it that fluidly connects an inlet port on the plasmapheresis centrifuge. A first skirt member on the feed tube has a smooth angled surface that helps to reduce foaming.Type: GrantFiled: March 26, 2018Date of Patent: July 20, 2021Assignee: HAEMONETICS CORPORATIONInventor: Taylor Korytko
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Patent number: 10980926Abstract: A method for collecting plasma includes determining the weight and hematocrit of a donor, and inserting a venous-access device into the donor. The method then withdraws blood from the donor through a draw line connected to a blood component separation device, and introduces anticoagulant into the withdrawn blood. The blood component separation device separates the blood into a plasma component and a second blood component, and the plasma component is collected from the blood component separation device and into a plasma collection container. The method may then calculate (1) a percentage of anticoagulant in the collected plasma component, and (2) a volume of pure plasma collected within the plasma collection container. The volume of pure plasma may be based, at least in part, on the calculated percentage of anticoagulant. The method may continue until a target volume of pure plasma is collected within the plasma collection container.Type: GrantFiled: May 4, 2020Date of Patent: April 20, 2021Assignee: HAEMONETICS CORPORATIONInventor: Michael Ragusa
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Patent number: 10980934Abstract: A method for collecting plasma includes determining the weight, height, and hematocrit of a donor, and calculating a donor plasma volume and a target plasma collection volume. The target plasma collection volume is based on the donor plasma volume and a target percentage of plasma. The method then withdraws blood from the donor through a line connected to a blood component separation device, and introduces anticoagulant into the withdrawn blood. The blood component separation device separates the blood into a plasma component and a second blood component, and the plasma component is collected from the blood component separation device and into a plasma collection container. The method may then calculate the volume of pure plasma collected within the plasma collection container, and continue processing/collecting until the calculated volume of pure plasma equals the target plasma collection volume.Type: GrantFiled: July 16, 2020Date of Patent: April 20, 2021Assignee: HAEMONETICS CORPORATIONInventor: Michael Ragusa
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Patent number: 10954549Abstract: In some embodiments, the invention provides methods for detecting and/or classifying an anticoagulant at a therapeutically relevant amount or higher in a patient, including subjecting a sample of a control blood component (known not to contain the anticoagulant) to a clotting assay in the presence of a Factor Xa reagent to obtain a control clotting measurement; and subjecting a sample of a blood component from a patient suspected of having the anticoagulant to the clotting assay in the presence of the Factor Xa reagent to obtain a patient clotting measurement, wherein the patient clotting measurement sample greater than the control clotting measurement indicates the presence of the anticoagulant at a therapeutically relevant amount or higher in the patient. In some embodiments, the invention includes methods for classifying an anticoagulant as an anti-Factor Xa or a direct thrombin inhibitor anticoagulant using a clotting assay in the presence of an ecarin reagent.Type: GrantFiled: November 5, 2019Date of Patent: March 23, 2021Assignee: Haemonetics CorporationInventors: Fowzia S. Zaman, Marc Doubleday
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Patent number: 10947966Abstract: A peristaltic pump includes a rotor and first and second rollers mounted on the rotor. The first and second rollers rotate between a disengaged, initially engaged and a fully engaged position with respect to a section of tubing. The rollers begin to occlude the tubing when in the initially engaged positon and fully occlude the tubing when in the fully engaged position. The pump also includes an encoder and a rotor controller. The encoder monitors the position of the first and second rollers as the rotor rotates. The rotor controller is in electrical communication with the encoder and controls the operation of the pump and rotor. The controller stops the rotation of the rotor in response to a stop command and based upon the monitored position of the first and second rollers such that either the first or second roller remains in the fully engaged positon.Type: GrantFiled: October 21, 2016Date of Patent: March 16, 2021Assignee: Haemonetics CorporationInventors: Gary Stacey, Edward Kaleskas
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Patent number: 10935559Abstract: In some embodiments, the invention provides a container adapted for detecting hyperfibrinolysis or fibrinolysis in a blood sample using viscoelastic analysis comprising an interior having a coating comprises an inhibitor of fibrinolysis.Type: GrantFiled: May 9, 2016Date of Patent: March 2, 2021Assignees: Haemonetics Corporation, The Regents of the University of Colorado, a body corporateInventors: Michael P. Chapman, Ernest E. Moore, Katherine M. Norem
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Patent number: 10837933Abstract: A system for detecting a fluid type within a blood processing device includes a voltage source for electrical connection to a first electrode and to a second electrode, and a resistor in series between the voltage source and the first and/or second electrode. The voltage source may apply a voltage across the first and second electrodes. The system also includes a voltage detector that is electrically connected to the resistor and measures a voltage drop across the resistor. A circuit electrically connected to the voltage detector determines the type of fluid in contact with the first and second electrode based, at least in part, upon the measured voltage drop.Type: GrantFiled: July 21, 2015Date of Patent: November 17, 2020Assignee: Haemonetics CorporationInventors: Sarah Kaczmarek, Bruno Piazzarolo, Samuel Vaughan
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Patent number: 10821220Abstract: A continuous flow centrifuge bowl includes a rotatable outer body, and a top and bottom core that are rotatable with the outer body. The bottom core has a wall extending proximally from a bottom wall. The proximally extending wall is radially outward from at least a portion of the top core and, together with the top core, defines a primary separation region in which initial separation of the whole blood occurs. The bowl may also have a secondary separation region located between the top core and the outer body, and a rotary seal that couples an inlet port and two outlet ports to the outer body. The inlet port may be connected to an inlet tube that extends distally into a whole blood introduction region. Additionally, one of the outlet ports may be connected to an extraction tube that extends into a region below the bottom core.Type: GrantFiled: April 9, 2019Date of Patent: November 3, 2020Assignee: Haemonetics CorporationInventors: Matthew Murphy, Dominique Uhlmann, Edward Powers, Michael Ragusa, Etienne Pagès
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Patent number: 10806847Abstract: A blood processing system for collecting plasma reduced platelets and anticipating plasma return includes a venous access device, a blood component separation device, a first return line, a recirculation line, and a second return line. The venous access device draws whole blood from a subject and returns blood components to the subject using a first pump. The blood component separation device separates the drawn blood into a first blood component and a second blood component, and sends the first blood component to a first blood component bag. The first return line fluidly connects the venous-access device and the blood component separation device. The recirculation line connects the first blood component container and the separation device. The second return line fluidly connects the first blood component container and the first return line and is configured to return the first blood component within the first blood container to the subject.Type: GrantFiled: January 27, 2016Date of Patent: October 20, 2020Assignee: Haemonetics CorporationInventor: Etienne Pagès
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Patent number: 10792416Abstract: A method for collecting plasma includes determining the weight, height, and hematocrit of a donor, and calculating a donor plasma volume and a target plasma collection volume. The target plasma collection volume is based on the donor plasma volume and a target percentage of plasma. The method then withdraws blood from the donor through a line connected to a blood component separation device, and introduces anticoagulant into the withdrawn blood. The blood component separation device separates the blood into a plasma component and a second blood component, and the plasma component is collected from the blood component separation device and into a plasma collection container. The method may then calculate the volume of pure plasma collected within the plasma collection container, and continue processing/collecting until the calculated volume of pure plasma equals the target plasma collection volume.Type: GrantFiled: October 25, 2017Date of Patent: October 6, 2020Assignee: HAEMONETICS CORPORATIONInventor: Michael Ragusa
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Patent number: 10758652Abstract: A method for collecting plasma includes determining the weight and hematocrit of a donor, and inserting a venous-access device into the donor. The method then withdraws blood from the donor through a draw line connected to a blood component separation device, and introduces anticoagulant into the withdrawn blood. The blood component separation device separates the blood into a plasma component and a second blood component, and the plasma component is collected from the blood component separation device and into a plasma collection container. The method may then calculate (1) a percentage of anticoagulant in the collected plasma component, and (2) a volume of pure plasma collected within the plasma collection container. The volume of pure plasma may be based, at least in part, on the calculated percentage of anticoagulant. The method may continue until a target volume of pure plasma is collected within the plasma collection container.Type: GrantFiled: May 30, 2017Date of Patent: September 1, 2020Assignee: Haemonetics CorporationInventor: Michael Ragusa
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Patent number: 10668207Abstract: A method for removing fat from salvaged blood includes transferring salvaged blood from a reservoir to a blood component separation device, and separating the blood into a plurality of blood components. The method may then transfer a volume of unwashed blood components from the blood component separation device back toward the reservoir, and re-centrifuge the blood components remaining within the blood component separation device. After re-centrifuging, the method transfers additional salvaged blood from the reservoir to the blood component separation device to refill the blood component separation device. The method may then wash the components within the bowl by introducing wash solution into the blood component separation device. The wash solution displaces a volume of fat from the blood component separation device and into a waste container. The method may then empty the washed blood components within the blood component separation device to a product container.Type: GrantFiled: July 13, 2016Date of Patent: June 2, 2020Assignee: Haemonetics CorporationInventors: Seth Kasper, Jordan Smelker, Samuel Vaughan
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Patent number: 10564145Abstract: An imaging system for a rotatable object includes an imaging unit configured to take a series of images of a portion of the rotatable object and a light source. The light source is directed at the rotatable object and is configured to generate pulses of light that illuminate the rotatable object during rotation of the rotatable object and allow the imaging unit to take the series of images of the rotatable object. The system also includes a synchronizer that monitors the rotational position of the rotatable object as it rotates, and a controller in communication with the imaging unit, the light source, and the synchronizer. The controller controls the operation of the imaging unit and/or the light source based upon the rotational position of the rotatable object such that each of the series of images is taken at the same rotational position of the rotatable object.Type: GrantFiled: September 28, 2016Date of Patent: February 18, 2020Assignee: Haemonetics CorporationInventors: Gary Stacey, James Sullivan
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Patent number: 10500330Abstract: A method for collecting and washing shed blood includes providing a blood salvage reservoir and a blood salvage system. The user may connect a vacuum inlet port on the reservoir to a vacuum outlet port on the salvage system, connect an inlet port on the reservoir to a patient, and connect a vacuum source to a vacuum connection port on the salvage system. The method may then (1) draw a vacuum on the reservoir to draw shed blood into the reservoir, (2) disconnect the reservoir from the surgical field and salvage system, and (3) connect a second reservoir. The first blood salvage reservoir may then be connected to an automated blood processing system, and the collected blood may be introducing into the automated blood processing system and washed. The blood processing system may then return a portion of the washed blood to the patient.Type: GrantFiled: October 7, 2015Date of Patent: December 10, 2019Assignee: Haemonetics CorporationInventors: Donald J. Schwarz, Seth Kasper, Lisa Fahey
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Patent number: 10501773Abstract: In some embodiments, the invention provides methods for detecting and/or classifying an anticoagulant at a therapeutically relevant amount or higher in a patient, including subjecting a sample of a control blood component (known not to contain the anticoagulant) to a clotting assay in the presence of a Factor Xa reagent to obtain a control clotting measurement; and subjecting a sample of a blood component from a patient suspected of having the anticoagulant to the clotting assay in the presence of the Factor Xa reagent to obtain a patient clotting measurement, wherein the patient clotting measurement sample greater than the control clotting measurement indicates the presence of the anticoagulant at a therapeutically relevant amount or higher in the patient. In some embodiments, the invention includes methods for classifying an anticoagulant as an anti-Factor Xa or a direct thrombin inhibitor anticoagulant using a clotting assay in the presence of an ecarin reagent.Type: GrantFiled: July 30, 2015Date of Patent: December 10, 2019Assignee: Haemonetics CorporationInventors: Fowzia S. Zaman, Marc Doubleday
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Publication number: 20190307941Abstract: A tubing set for a blood processing system includes a first connector, a first tube, and a second tube. The first connector is configured to connect to a separation device within the blood processing system, and has a first inlet configured to be fluidly connected to an outlet of the separation device. The first connector also has an outlet and a second inlet. The first tube fluidly connects to the outlet and fluidly connects the separation device and a blood component storage container. The second tube is fluidly connected to the second inlet and fluidly connects the separation device and a saline storage container. The second tube may include a second connector that connects to the saline storage container.Type: ApplicationFiled: June 14, 2017Publication date: October 10, 2019Applicant: Haemonetics CorporationInventor: Christopher S. McDowell
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Publication number: 20190151200Abstract: A top for a plasma storage container includes a top body that defines the structure of the top and seals an opening of the plasma storage container. The top also includes a first opening and a vent opening extending through the top body. A septum is located at least partially within the first opening and includes an aperture therethrough. The septum allows a blunt cannula to pass through the aperture to access the interior of the plasma storage container. The top also includes a hydrophobic membrane located on underside of the top body. The membrane covers the vent opening and allows air to vent through the vent opening during plasma collection.Type: ApplicationFiled: May 16, 2017Publication date: May 23, 2019Applicant: Haemonetics CorporationInventor: Christopher S. McDowell
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Patent number: 10293097Abstract: A continuous flow centrifuge bowl includes a rotatable outer body, and a top and bottom core that are rotatable with the outer body. The bottom core has a wall extending proximally from a bottom wall. The proximally extending wall is radially outward from at least a portion of the top core and, together with the top core, defines a primary separation region in which initial separation of the whole blood occurs. The bowl may also have a secondary separation region located between the top core and the outer body, and a rotary seal that couples an inlet port and two outlet ports to the outer body. The inlet port may be connected to an inlet tube that extends distally into a whole blood introduction region. Additionally, one of the outlet ports may be connected to an extraction tube that extends into a region below the bottom core.Type: GrantFiled: November 5, 2013Date of Patent: May 21, 2019Assignee: Haemonetics CorporationInventors: Matthew Murphy, Dominique Uhlmann, Edward Powers, Michael Ragusa, Etienne Pagès
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Patent number: 10228310Abstract: A flow through fluid sampling system includes a sample tube and a cap. The sample tube is configured to collect a sample of a fluid and has an open top. The cap is configured to be secured to the sample tube to close the open top. The cap includes an inflow port configured to allow fluid to enter the fluid sample tube, an outflow port configured to allow fluid to leave the sample tube.Type: GrantFiled: January 12, 2015Date of Patent: March 12, 2019Assignee: Haemonetics CorporationInventors: Michael Ragusa, Matthew J. Murphy