Patents Assigned to Hamilton Bonaduz AG
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Publication number: 20130118118Abstract: A tool device for the automated opening of flip tubes including an actuating plunger which is provided and configured to move the actuating portion at least in open direction and thereby to exert an opening moment on the lid portion, and wherein the device further includes a damping means which is configured to exert a damping moment on the container lid at least during a period of the actuation of the actuating portion by the actuating plunger, which damping moment is less in amount and is in an opposite direction compared to the opening moment.Type: ApplicationFiled: May 18, 2011Publication date: May 16, 2013Applicant: HAMILTON BONADUZ AGInventors: Walter Kubler, Rainer Beckbissinger, Urs Muller
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Publication number: 20130001242Abstract: The invention relates to a metering device (10; 10a; 10b) comprising a guide tube (20; 20a; 20b), a piston (24; 24a; 24b) inserted displaceably in the guide tube (20; 20a; 20b), an actuating assembly (40; 40a; 42) for exerting a force on the piston (24; 24a; 24b) in order to displace the piston (24; 24a; 24b) in the guide tube (20; 20a; 20b), and a chamber (28, 30) for receiving a medium to be metered (34), said medium to be metered (34) can be aspirated or dispensed according to a displacement of the piston (24; 24a; 24b), the actuating assembly (40; 40a; 42) being equipped for a magnetic interaction with the piston (24; 24a; 24b).Type: ApplicationFiled: January 5, 2011Publication date: January 3, 2013Applicant: HAMILTON BONADUZ AGInventors: Meinrad Hofstetter, Vinzenz Kirste
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Patent number: 8245586Abstract: For aspiration and dispensation of a metering fluid, a pipetting apparatus comprises a work fluid which differs from the former, the work fluid being accommodated in a work space with a variable volume which extends along a channel axis and, with reference to the latter, is formed by a piston-cylinder system at least along an axial section of the channel axis, having a cylinder which delimits the work space along a cylinder section in the radial direction and a piston which delimits the work space in a first axial direction, the cylinder and the piston being arranged so that they can move with respect to each other such that the piston-cylinder system has an axial longitudinal end region for metering, which is open for aspiration and dispensation, and an axial longitudinal end region for work which is closed by the piston, the piston being designed as an outer piston and surrounding the cylinder on the outside in the longitudinal end region for work of the piston-cylinder system.Type: GrantFiled: May 5, 2009Date of Patent: August 21, 2012Assignee: Hamilton Bonaduz AGInventors: Armin Panzer, Patrick Schelling
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Publication number: 20120085181Abstract: The present invention relates to a temperature adjustment device (10) for adjusting the temperature of at least one sample container (12), which temperature adjustment device (10) comprises, for optional heat-transferring coupling of the sample container (12) therewith and for isolation of the sample container (12) therefrom, at least one sample container holder (16) extending along a holder axis (A), the temperature adjustment device (10) comprising a first temperature adjustment zone (26) and a second temperature adjustment zone (31) which can be operated separately therefrom, the first and second temperature adjustment zones (26, 31) being arranged in different axial regions of the sample container holder (16) relative to the holder axis (A).Type: ApplicationFiled: September 13, 2011Publication date: April 12, 2012Applicants: Hamilton Company, Hamilton Bonaduz AGInventors: Carsten ETZOLD, Frieder Neuhäusser-Wespy, Mareen Schmökel, Claudio Schmid, Johann Seeber
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Publication number: 20120017704Abstract: Pipette device (10), at least for dispensing metering liquid by increasing the pressure of a working fluid, comprising a metering liquid receptacle (38) which is filled, at least in part, with working fluid and has a pipette opening (36) as a first tapering of cross-section of flow, through which metering liquid can be dispensed from the metering liquid receptacle (38) as a function of the pressure of the working fluid, and comprising a pressure change device (40) which is designed to change the pressure of the working fluid in the metering liquid receptacle (38), wherein the pipette device (10) comprises a throttle point (42) in a pipette duct (12) filled with working fluid during normal operation as a further tapering of cross-section of flow, said throttle point being arranged fluid-mechanically between the metering liquid receptacle (38) and the pressure change device (40) and being dimensioned in such a way that a ratio of a flow resistance (R1) of the pipette opening (36) for dispensed metering liquid tType: ApplicationFiled: July 26, 2011Publication date: January 26, 2012Applicant: Hamilton Bonaduz AGInventors: Vinzenz KIRSTE, Helmut Knapp, Urs Lendenmann, Noa Schmid, Tobias Seiler, Fabian Winter
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Publication number: 20120009100Abstract: The present invention relates to a pipette tip (10), for aspirating and dispensing pipetting fluid, which extends along a pipette tip longitudinal axis (L), a first axial longitudinal end region (16) of the pipette tip (10), as a pipetting longitudinal end region (16), comprising a pipette opening (12), through which pipetting fluid can flow in the course of operation, and a second axial longitudinal end region (18) of the pipette tip (10), as a coupling longitudinal end region (18), which opposes the pipetting longitudinal end region (16) in the axial direction, comprising a coupling shape, for coupling, preferably releasable coupling, to a coupling counter-shape of a pipette device, the pipette tip (10) comprising an outer hydrophobic region (32) on the outside (30) thereof and an inner hydrophobic region (26) on the inside (28) thereof, each having a quadratic roughness in a range of 100 nm to 1000 nm, preferably of 150 nm to 750 nm and particularly preferably of 200 nm to 500 nm, and having a peak-to-peakType: ApplicationFiled: July 12, 2011Publication date: January 12, 2012Applicant: HAMILTON BONADUZ AGInventors: Vinzenz KIRSTE, Renato NAY, Rainer BECKBISSINGER
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Publication number: 20110318242Abstract: A metering device for the aspiration and dispensing of a metered medium (26) by means of a working substance through a metering opening (22a) into a metering chamber (24), and out of the same, comprises a working chamber (12) filled at least partially with a compressible working substance, a pressure change apparatus (14, 16) which is designed to change the pressure of the working substance in the working chamber, and a metering chamber (24) comprising the metering opening (22a), wherein the working chamber (12) and the metering chamber (24) are connected by a valve (28) which can be switched between a blocking position, in which pressure transmission, in particular a working substance flow, from the working chamber (12) into the metering chamber (24) by way of the valve (28) is prevented, and a passage position, in which pressure transmission from the working chamber (12) into the metering chamber (24) by way of the valve (28) is permitted.Type: ApplicationFiled: November 28, 2008Publication date: December 29, 2011Applicant: HAMILTON BONADUZ AGInventor: Renato Nay
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Publication number: 20110236962Abstract: The present invention relates to a calibratable sensor unit for a reaction vessel, such as for example a fermenter (48), in particular a disposable fermenter, comprising at least one sensor device (14) to be calibrated and at least one compartment (26, 28, 30) containing a calibrating agent, the at least one sensor device and the at least one compartment (26, 28, 30) being accommodated movably relative to one another in a housing (12) that is connected to or can be connected to the reaction vessel (48), wherein the calibrating unit (10) is arranged to calibrate the at least one sensor device (14) by contact with the calibrating agent before chemical and/or physical parameters of a measurement substance are measured with the at least one sensor device (14).Type: ApplicationFiled: February 10, 2011Publication date: September 29, 2011Applicant: HAMILTON BONADUZ AGInventors: Andreas LOEBBERT, Dirk SCHOENFUSS
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Publication number: 20110206577Abstract: The invention relates to a radial sliding seal component (10), particularly for use in metering devices, such as syringes, pipetting piston-cylinder arrangements, and the like, comprising a sealing component (12) working together with at least one pretensioning component (14), wherein the sealing component (12) comprises a sealing segment (16) extending in the axial direction and in the circumferential direction, preferably running in the circumferential direction, on which a sealing surface (18) facing in a first radial direction for sealing and sliding contact in at least the axial direction is formed on a working surface extending in the axial direction and in the circumferential direction, preferably running in the circumferential direction, and on which a pretensioning surface (20) extending in a second radial direction opposite to the first is formed for engaging with the pretensioning component (14) for transferring the radial pretensioning force, wherein the pretensioning component (14) comprises a spType: ApplicationFiled: November 5, 2008Publication date: August 25, 2011Applicant: HAMILTON BONADUZ AGInventor: Klaus Leckebusch
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Publication number: 20100312194Abstract: A syringe comprises a syringe body (12) having an axial inner recess (14) extending in the direction of a longitudinal axis of the syringe body (L), a piston (16) being guided in an axially moveable manner in said inner recess and contributing to the delimitation of a fluid-receiving volume together with a section of a wall (14a) radially delimiting the inner recess (14), and having a needle (24) that can be or is connected to a longitudinal end (12a) of the syringe body (12), wherein the needle (24) has a coupling geometry (28) at the longitudinal end (24a) thereof that is closer to the syringe body, wherein the needle (24) can be connected by said coupling geometry to a counter coupling geometry (30) of the syringe body (12), wherein the geometry composed of the coupling geometry (28) and counter coupling geometry (30) comprises an insertion section (32), which in the assembled state of the syringe (10) is received in a coupling recess (34) of the respectively other geometry, and wherein furthermore safetyType: ApplicationFiled: September 19, 2008Publication date: December 9, 2010Applicant: HAMILTON BONADUZ AGInventor: Klaus Leckebusch
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Patent number: 7704359Abstract: The present application relates to a pressurized reference electrode and to a process for its production, said reference electrode comprising a chamber (11) which has a flowable reference electrolyte, and a portion of the wall of said chamber being formed from porous material (10) for contacting said reference electrode with a measuring medium, and said chamber being under overpressure, which is characterized in that the overpressure is generated in said reference electrode by introducing a gas or/and a liquid through said porous material of the wall in said chamber, or introducing said reference electrolyte into said chamber and closing said chamber under pressure.Type: GrantFiled: December 15, 2004Date of Patent: April 27, 2010Assignee: Hamilton Bonaduz AGInventors: Fabio Sovrano, Rolf Thrier
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Publication number: 20090277285Abstract: For aspiration and dispensation of a metering fluid, a pipetting apparatus comprises a work fluid which differs from the former, the work fluid being accommodated in a work space with a variable volume which extends along a channel axis and, with reference to the latter, is formed by a piston-cylinder system at least along an axial section of the channel axis, having a cylinder which delimits the work space along a cylinder section in the radial direction and a piston which delimits the work space in a first axial direction, the cylinder and the piston being arranged so that they can move with respect to each other such that the piston-cylinder system has an axial longitudinal end region for metering, which is open for aspiration and dispensation, and an axial longitudinal end region for work which is closed by the piston, the piston being designed as an outer piston and surrounding the cylinder on the outside in the longitudinal end region for work of the piston-cylinder system.Type: ApplicationFiled: May 5, 2009Publication date: November 12, 2009Applicant: HAMILTON BONADUZ AGInventors: Armin Panzer, Patrick Schelling
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Patent number: 7581660Abstract: A liquid-metering device is disclosed, in particular, a pipetting device for aspirating and dispensing liquids. The device comprises a vessel which is at least partially filled with gas and has an opening through which liquid is received or discharged, a gas-pressure-changing device for changing the gas pressure in the vessel, a state-variable-detecting device for detecting at least one state variable of the gas in the vessel, and a control device which activates the gas-pressure-changing device as a function of the state variable detected by the state-variable-detecting device. The control device is a regulating device which, during a regulating time segment between liquid reception and liquid discharge, activates the gas-pressure-changing device as a function of the detected state variable such that the actual gas pressure in the vessel is kept essentially at a predetermined gas pressure.Type: GrantFiled: November 9, 2005Date of Patent: September 1, 2009Assignee: Hamilton Bonaduz AGInventors: Renato Nay, Markus Bentz, Rene Ackermann
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Publication number: 20070007149Abstract: The present invention relates to an aqueous solution for calibrating conductometric measuring cells.Type: ApplicationFiled: November 18, 2005Publication date: January 11, 2007Applicant: HAMILTON BONADUZ AGInventor: Hannes Buehler
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Patent number: 7033543Abstract: A pipette device has a coupling stud on which a pipette tip can be stuck in a slipping-on direction for coupling. The coupling stud has an adjustable pre-stress member that can be adjusted into a prestress state and a release state via an actuation device which is provided in the coupling stud. The pipette tip has an axial stop which interacts with a counter-stop of the coupling stud in an axial coupling position of the pipette tip. The prestress member in its prestress state acts upon a working surface of the stuck-on pipette tip having a surface component of the pipette tip, which extends radially inward, turned away from the stuck on direction, in such a way that it abuts sealingly on the working surface, and prestresses the pipette tip on the pipette unit into the axial coupling position. The prestress member, in its releasing state, substantially releases the working surface of the pipette tip (101).Type: GrantFiled: April 14, 2000Date of Patent: April 25, 2006Assignee: Hamilton Bonaduz AGInventors: Armin Panzer, Johann L. Camenisch
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Patent number: 6938504Abstract: The invention relates to a method for evaluating a liquid dosing process in a container which is at least partially filled with a gas. According to the inventive method, a temporal course of at least one state variable p of a medium contained in said container is determined essentially over the entire duration of the dosing process. The temporal course (40; 40?) of the at least one state variable (p) is graphically or mathematically compared with a pre-determined state variable nominal range (42; 42?; 242) by means of a correlation method, and an evaluation result (S6, S14, S16) is obtained according to the results of the comparison.Type: GrantFiled: March 7, 2002Date of Patent: September 6, 2005Assignee: Hamilton Bonaduz AGInventor: Johann L. Camenisch
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Publication number: 20050133369Abstract: The present application relates to a pressurized reference electrode and to a process for its production, said reference electrode comprising a chamber (11) which has a flowable reference electrolyte, and a portion of the wall of said chamber being formed from porous material (10) for contacting said reference electrode with a measuring medium, and said chamber being under overpressure, which is characterized in that the overpressure is generated in said reference electrode by introducing a gas or/and a liquid through said porous material of the wall in said chamber, or introducing said reference electrolyte into said chamber and closing said chamber under pressure.Type: ApplicationFiled: December 15, 2004Publication date: June 23, 2005Applicant: HAMILTON BONADUZ AGInventors: Fabio Sovrano, Rolf Thrier
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Patent number: 6468408Abstract: The invention relates to a polymeric electrolyte which is part of an electrochemical reference electrode and which is used in potentiometric and amperometric sensors. The polymeric electrolyte is a hydrogel which is stable in a large pH-range and stable against organic solvents.Type: GrantFiled: February 8, 2001Date of Patent: October 22, 2002Assignee: Hamilton Bonaduz AGInventors: Rolf Thrier, Stephan Buschor, Heiner Bührer, Hannes Bühler
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Patent number: 4830832Abstract: A pipette includes a pipette body made of plastic material and a pipette piston made of plastic material that is also electrically conductive. The pipette is automatically received or discarded in a pickup device which has an electric transmission filament. A pipetting apparatus has a pickup device for receiving test containers, a pickup section for a microstandard plate, a pipette hopper, and a dosing device. For automatic pipetting, the dosing device receives the pipettes, conveys the pipettes while simultaneously changing the distance of the pipettes to the test containers, absorbs liquid through the pipette, conveys the pipettes while simultaneously changing the distance of the pipette to the microstandard plate, discharges the liquid, and finally ejects the pipette.Type: GrantFiled: December 12, 1986Date of Patent: May 16, 1989Assignee: Hamilton Bonaduz AGInventors: Renato Arpagaus, Herwig Leyssens