Abstract: Tracking the process of a client activity via an electronic system involves the provision of user interfaces by which data are communicated to user. Optimizing the generation of these user interfaces in a cloud-based system reduces processing resources required by the cloud-based portion, improves the user experience on the local portions, and improves the data collected by users. Using, as described herein, historical data known to the cloud-based portion related to both the user and the client, the user interfaces are updated to show progress of the activity and to organize the tasks for the given user in an optimal arrangement. Reports may also be generated regarding the efficacy of the users in shepherding the activity to completion in a more efficient manner. Various user interface elements are integrated into the cloud-based system for quick provision of activity and task statuses to the user.

Abstract: It has been surprisingly discovered that administration of nitrite to subjects causes a reduction in blood pressure and an increase in blood flow to tissues. The effect is particularly beneficial, for example, to tissues in regions of low oxygen tension. This discovery provides useful treatments to regulate a subject's blood pressure and blood flow, for example, by the administration of nitrite salts. Provided herein are methods of administering a pharmaceutically-acceptable nitrite salt to a subject, for treating, preventing or ameliorating a condition selected from: (a) ischemia-reperfusion injury (e.g., hepatic or cardiac or brain ischemia-reperfusion injury); (b) pulmonary hypertension (e.g., neonatal pulmonary hypertension); or (c) cerebral artery vasospasm.

Abstract: A power cooperation system among exerciser apparatuses includes at least two exercise apparatuses. The exercise apparatuses have a wireless communication channel therebetween, and each has a motion module, a power generation module, a power storage module and at least one power consuming module. At least one of the exercise apparatuses has a power transmitting module connected to the power generation module and/or the power storage module and being able to transmit an energy wave. The other exercise apparatus has a power receiving module connected to the power storage module for being able to receive the energy wave. Under this arrangement, the power cooperation system is configured to achieve power sharing among exercise apparatuses and ensure that every exercise apparatus has enough power to keep available, and using the excess power by the respective exercise apparatuses efficiently.

Abstract: Aspects described herein pertain to monitoring and automatic re-instantiation of a communication session using a monitoring system and/or device and one or more remote systems and/or devices. If a disruption in a communication session occurs, an automated reconnect agent executable can execute on one or more of the remote systems and/or devices to automatically re-instantiate the communication session without or absent requiring human intervention. For example, the automated reconnect agent executable can use automatic reconnect parameters to automatically re-instantiate a pre-existing communication session without or absent requiring a human operator to reenter login or other authentication credentials or engage in some other form of authorization or authentication in order to reestablish the communication session between a monitoring system and/or device and one or more remote systems and/or devices.

Abstract: Microcapsules are described that comprise (a) a liquid aqueous or hydrogel core; (b) a semipermeable membrane surrounding said core; (c) live animal cells (e.g., pancreatic cells) in the core; and (d) oxygen-generating particles in said core, said oxygen-generating particles included in said microcapsules in an amount sufficient to lengthen the duration of viability of said animal cells in said microcapsules. Compositions comprising such microcapsules and uses thereof, such as in treating diabetes, are also described.

Abstract: Contemplated compositions and methods are directed to prevent and/or treat various autoimmune diseases that are typically associated with glycan dysregulation, and especially autoimmune demyelinating diseases. Further especially contemplated aspects include animal models and systems for screening compounds to treat and/or prevent such diseases.

Abstract: The present invention relates to methods of inducing a T-cell response against a EGFRvIII in a subject. These method comprise administering to a subject a composition which expresses at least one immunogenic polypeptide, the amino acid sequence of which comprise a plurality of EGFRvIII polypeptide sequences, the sequence of which each comprise EEKKGNYV (SEQ ID NO: 3), and/or administering the polypeptide itself.

Abstract: Disclosed are compounds of formula (I) which possess pesticidal, especially nematicidal properties wherein in the structural elements have the meaning as indicated in the description.

Abstract: The invention relates to methods of preparing a bone matrix solution, a bone matrix implant, and variants thereof. The invention also relates to methods of cell culture using the same. The invention further relates to bone matrix scaffolds comprising one or more bone matrix nanofibers, methods of preparing, and methods of use thereof. The invention also relates to methods of culturing cells and promoting differentiation of stem cells using the same.

Abstract: The present disclosure provides a system and method of determining a risk score for triage. In particular, a system is provided for providing an assessment of risk of a cardiac event for a patient, for example an incoming patient to a hospital emergency department complaining of chest pain. In the disclosure, the system includes an input device for measuring physiological data based vital signs parameter of the patient, a twelve-lead electrocardiogram (ECG) device for establishing an ECG obtained from results of the electrocardiography procedure, and determining an ECG parameter and a heart rate variability (HRV) parameter therefrom. An ensemble-based scoring system is further provided, establishing weighted classifier based on past patient data and where the vital signs parameter, the ECG parameter and the HRV parameter are compared to corresponding weighted classifiers to determine a risk score. A corresponding method to determine a risk score for triage is also provided.

Abstract: The present disclosure describes systems and methods for using patient-specific genomic information to optimize or de-risk therapy for the patient. A user may identify a medication for consideration for prescription to a patient, and a genetic variant of the patient affecting a first protein. An analyzer may identify a second medication targeting the first protein, and may retrieve adverse event data from an adverse event database for patients co-medicated with both the first medication and second medication. The analyzer may determine, based on rates of adverse events, the likelihood of an adverse event occurring through co-medication of the first medication and second medication. Based on the likelihood, and based on a correspondence or non-correspondence between a protein activation characteristic of the first medication and the effect of the genetic variant of the patient, the analyzer may indicate or contra-indicate the first medication for the patient.

Abstract: Without limitation, some embodiments comprise a method of treatment for promoting recovery of peripheral neuropathy in a subject, including administering to a subject in need of such treatment a therapeutically effective amount of a composition comprised of thymosin beta 4, amino acid sequences LKKTET or LKKTNT, and/or any conservative variants thereof, or an agent that stimulates production of any of those materials, or a conservative variant thereof.

Abstract: HIV neutralizing peptides, sulfated HIV-1 envelope proteins and immunogenic fragments thereof are disclosed, as well as nucleic acids encoding these molecules and methods of producing these peptides, envelope proteins and fragments. Methods are also provided for the treatment or prevention of a human immunodeficiency type 1 (HIV-1 ) infection. The methods can include administering to a subject an HIV neutralizing peptide, sulfated HIV-1 envelope protein or immunogenic fragment thereof as disclosed herein. In several embodiments, administering the HIV neutralizing peptide, sulfated HIV-1 envelope protein or immunogenic fragment generates an immune response in a subject.

Abstract: A rowing simulation trainer includes a base frame, a pulling unit, an inertia wheel unit and a guiding unit. The pulling unit includes a shaft, a first belt wheel, two cord wheels, two pulling cords, two handgrips and two elastic coiled plates. The guiding unit includes two mounting tubes. Each of the two pulling cords extends through one of the two mounting tubes. Thus, the two cord wheels and the two pulling cords cooperate to drive the inertia wheel unit and are respectively operated independently without interfering with each other. In addition, the two pulling cords are limited by the two mounting tubes so that the two pulling cords are kept in line with and will not be deflected from the two cord wheels.

Abstract: The present invention discloses an intelligent household air purification cabinet type body-building apparatus, comprising a box body, a running machine, an air purifier and a power supply. The intelligent household air purification cabinet type body-building apparatus is further provided with an intelligent control system which comprises a controller, a central control computer, a pressure frequency detection device, an audio device, a display device and a signal receiving and transmitting device. A use method of the body-building apparatus comprises five steps of facility unfolding and need setting, environment preparation, body-building process, statistical analysis of body-building completion, and folding. The present invention has the advantages of small occupation space, complementary functions, no need of adding a power supply, supply of body-building environment beneficial to a human body, convenient operation and capability of long-term sustainable improvement.

Abstract: A downtime registration service is discussed herein that enables client systems that rely on electronic record management systems to continue generating records during a downtime event for the electronic record management system without relying on a workaround that requires temporary identifiers or reentry of data. The downtime registration system improves the efficiency and accuracy of electronic systems because workarounds that involve using temporary identifiers, or reentering data collected during the downtime, increase the amount of work done and the chance for errors to be introduced into the records. The client systems are in communication with an outside facility providing advanced services, which track the records generated during normal operation (i.e., not downtime) so that new records created during downtime properly reuse existing record identifiers or assign new identifiers that correspond to the clients' record keeping policies.

Abstract: Automated criteria template generation and automated criteria population in a contract model for improving the efficiency, functionality, and accuracy of systems for contract modeling and claim valuation are provided. When modeling contracts for claim valuation, terms are entered into a contract model, and criteria are entered that determine whether a particular term matches an item on a claim. A contract modeling and claim valuation system collects and stores criteria data that have matched service terms during claim valuations, and prioritizes the criteria for building criteria templates for associated service terms. When a contract model is being built, and entry of a particular service term is received, the contract modeler searches for criteria templates that are associated with the service term. A criteria template is selected, and the criteria in the criteria template are automatically loaded into a criteria section of the contract modeler graphical user interface.

Abstract: Processes for detecting Dengue virus (DENV) nucleic acid in a sample are provided including producing an amplification product by amplifying DENV nucleotide sequence and detection of an amplification by hybridization of a probe or other technique. The processes use primers or probes with introduced mutations and or degenerate bases that provide excellent superiority in detection and serotyping of DENV in a sample.

Abstract: Improvements in an exercise machine where the fan blades alter the resistance created by the blades or vanes by moving a cone that pushes the blades out from a central position. The blades or vanes push against the cone with springs. The cone is then moved into or out of the central axle to alter the effective diameter of the blades or vanes. A twist or contouring of the blades or vanes can be obtained at the same time to alter the resistance. In another embodiment, the fan blades can be individually or collectively adjusted to change the resistance. As the diameter is increased the speed of the blade tips increases as a squared function of the radius without changing the rotational speed of the vane(s). The shape, angle, scoop or tilt of the blade or vanes can also be altered to change the resistance.

Abstract: Biometric markers are seen as a secure and convenient way to control an individual's access to systems. The data that comprise these access controls, however, can be spoofed by nefarious third parties. Therefore, systems and methods are provided that track metadata related to the usage of biometric markers as access control devices to improve the security of systems using biometric markers for access control and to improve the speed and efficiency for systems when re-granting access for an individual in the event that access was revoked or suspended. A bureau collects metadata related to the authentication of individuals via biometric markers and the activities of the individual and the systems accessed. These metadata are used by the bureau to alert affected parties of potential misuse of biometric data and to reduce the processing requirements, storage requirements, and number of communications to on-board or re-authenticate an individual.