Patents Assigned to Heartport, Inc.
  • Patent number: 8915959
    Abstract: The subject invention relates to a valve replacement system together with methods of preparation and use, are provided for endovascular replacement of a heart valve in a host. The valve replacement system includes up to five components: a prosthetic valve device, a valve introducer device, an intraluminal procedure device, a procedure device capsule, and a tissue cutter. The system provides for endovascular removal of a malfunctioning valve and subsequent replacement with a permanent prosthetic heart valve.
    Type: Grant
    Filed: October 23, 2001
    Date of Patent: December 23, 2014
    Assignee: Heartport, Inc.
    Inventor: John H. Stevens
  • Patent number: 8617190
    Abstract: A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple.
    Type: Grant
    Filed: March 28, 2011
    Date of Patent: December 31, 2013
    Assignee: Heartport, Inc.
    Inventors: Hanson S. Gifford, III, Lee R. Bolduc, Jeffrey A. Stein, Paul C. DiCesare, Peter F. Costa, William A. Holmes
  • Patent number: 7935129
    Abstract: A device for engaging tissue having a preexisting opening includes a generally annular-shaped ring having a width disposed about a longitudinal axis, and at least two staple members extending from the ring. Each of the at least two staple members have a thickness and at least a distal portion formed of an elastic material. The distal portions of the staple members have a first configuration, where the distal portions are separated by a first distance and wherein the distal portions are substantially parallel to the longitudinal axis, and a second configuration, where the distal portions are separated by a second distance, the second distance being less than the first distance, and the at least two staple members engage tissue surrounding the preexisting opening. The annular-shaped ring has a width that is greater than the thickness of the at least two staple members.
    Type: Grant
    Filed: March 1, 2004
    Date of Patent: May 3, 2011
    Assignee: Heartport, Inc.
    Inventors: Hanson S. Gifford, III, Lee R. Bolduc, Jeffrey A. Stein, Paul C. DiCesare, Peter F. Costa, William A. Holmes
  • Patent number: 7763041
    Abstract: Surgical clips, and methods of use thereof, are provided for tissue approximation and attachment, and more particularly, for sealingly joining a graft vessel to a target vessel. The graft vessel has a free end and a graft vessel wall defining a graft lumen. The target vessel has a target vessel wall defining a target lumen and has an opening in the target vessel wall. The anastomosis clip includes a clip body having a distal extremity with a distal end and a proximal extremity with a proximal end. The distal end is configured to penetrate through the graft vessel wall near the free end and through the target vessel wall near the opening such that both the distal and proximal ends of the clip body are outside the graft and target vessels. At least a portion of the clip body is shapable so as to compress the graft vessel wall against the target vessel wall with the target vessel lumen in communication with the graft vessel lumen.
    Type: Grant
    Filed: July 29, 2003
    Date of Patent: July 27, 2010
    Assignee: Heartport, Inc.
    Inventors: Lee R. Bolduc, Hanson S. Gifford, III, James I. Fann
  • Patent number: 7651510
    Abstract: Systems for anastomosing a first hollow tissue structure to a second hollow tissue structure are disclosed. In an exemplary embodiment, such a system comprises at least one tissue securing member adapted to secure the first and second hollow tissue structures together, and a device for applying the tissue securing member to the tissue structures. The tissue securing member is preferably configured to pass through only one of the tissue structures, and is movable from a first configuration to a second configuration which results in a compressive force being applied to the tissue structures. The systems are particularly useful for performing anastomosis of blood vessels in heart surgery.
    Type: Grant
    Filed: January 12, 2001
    Date of Patent: January 26, 2010
    Assignee: Heartport, Inc.
    Inventors: Lee R. Bolduc, James R. Gannoe, Philip R. Houle
  • Patent number: 7213601
    Abstract: A method of treatment of congestive heart failure comprises the steps of introducing an aortic occlusion catheter through a patient's peripheral artery, the aortic occlusion catheter having an occluding member movable from a collapsed position to an expanded position; positioning the occluding member in the patient's ascending aorta; moving the occluding member from the collapsed shape to the expanded shape after the positioning step; introducing cardioplegic fluid into the patient's coronary blood vessels to arrest the patient's heart; maintaining circulation of oxygenated blood through the patient's arterial system; and reshaping an outer wall of the patient's heart while the heart is arrested so as to reduce the transverse dimension of the left ventricle.
    Type: Grant
    Filed: September 17, 2003
    Date of Patent: May 8, 2007
    Assignee: Heartport, Inc
    Inventors: John H. Stevens, Lee R. Bolduc, Stephen W. Boyd, Brian S. Donlon, Hanson S. Gifford, III, Philip R. Houle, Daniel C. Rosenman
  • Patent number: 7131447
    Abstract: A method for closed-chest cardiac surgical intervention relies on viewing the cardiac region through a thoracoscope or other viewing scope and endovascularly partitioning the patient's arterial system at a location within the ascending aorta The cardiopulmonary bypass and cardioplegia can be induced, and a variety of surgical procedures performed on the stopped heart using percutaneously introduced tools. The method of the present invention will be particularly suitable for forming coronary artery bypass grafts, where an arterial blood source is created using least invasive surgical techniques, and the arterial source is connected to a target location within a coronary artery while the patient is under cardiopulmonary bypass and cardioplegia.
    Type: Grant
    Filed: April 26, 2004
    Date of Patent: November 7, 2006
    Assignee: Heartport, Inc.
    Inventors: Wesley D. Sterman, Lawrence C. Siegel, Patricia E. Curtis, John H. Stevens, William S. Peters, Timothy R. Machold
  • Patent number: 7122044
    Abstract: A stapler for stapling a tubular structure to another structure. The stapler has an anvil which is expandable from a collapsed position to an expanded position. The stapler has a recess which receives at least a portion of the tubular structure and a shoulder which receives an everted end of the tubular structure. A first actuator moves the anvil relative to the shoulder for compressing the structures which are to be stapled together. A second actuator is used for driving the staples through the structures to be stapled together.
    Type: Grant
    Filed: April 28, 2004
    Date of Patent: October 17, 2006
    Assignee: Heartport, Inc.
    Inventors: Lee R. Bolduc, Christopher F. Heck
  • Patent number: 7112211
    Abstract: A system for performing an end-to-side vascular anastomosis. including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple.
    Type: Grant
    Filed: January 9, 2003
    Date of Patent: September 26, 2006
    Assignee: Heartport, Inc.
    Inventors: Hanson S. Gifford, III, Lee R. Bolduc, Jeffrey A. Stein, Paul C. DiCesare, Peter F. Costa, William A. Holmes
  • Patent number: 7100614
    Abstract: Devices, systems, and methods are provided for accessing the interior of the heart and performing procedures therein while the heart is beating. In one embodiment, a tubular access device having an inner lumen is provided for positioning through a penetration in a muscular wall of the heart, the access device having a means for sealing within the penetration to inhibit leakage of blood through the penetration. The sealing means may comprise a balloon or flange on the access device, or a suture placed in the heart wall to gather the heart tissue against the access device. An obturator is removably positionable in the inner lumen of the access device, the obturator having a cutting means at its distal end for penetrating the muscular wall of the heart. The access device is preferably positioned through an intercostal space and through the muscular wall of the heart.
    Type: Grant
    Filed: March 15, 2002
    Date of Patent: September 5, 2006
    Assignee: Heartport, Inc.
    Inventors: John H. Stevens, Bruce A. Reitz, Alex T. Roth, William S. Peters, Hanson S. Gifford
  • Patent number: 7056326
    Abstract: Systems for anastomosing a first hollow tissue structure to a second hollow tissue structure are disclosed. In an exemplary embodiment, such a system comprises at least one tissue securing member adapted to secure the first and second hollow tissue structures together, and a device for applying the tissue securing member to the tissue structures. The tissue securing member is preferably configured to pass through only one of the tissue structures, and is movable from a first configuration to a second configuration which results in a compressive force being applied to the tissue structures. The systems are particularly useful for performing anastomosis of blood vessels in heart surgery.
    Type: Grant
    Filed: June 2, 2004
    Date of Patent: June 6, 2006
    Assignee: Heartport, Inc.
    Inventors: Lee R. Bolduc, James R. Gannoe, Philip R. Houle
  • Patent number: 7028692
    Abstract: A method for closed-chest cardiac surgical intervention relies on viewing the cardiac region through a thoracoscope or other viewing scope and endovascularly partitioning the patient's arterial system at a location within the ascending aorta. The cardiopulmonary bypass and cardioplegia can be induced, and a variety of surgical procedures performed on the stopped heart using percutaneously introduced tools. The method of the present invention will be particularly suitable for forming coronary artery bypass grafts, where an arterial blood source is created using least invasive surgical techniques, and the arterial source is connected to a target location within a coronary artery while the patient is under cardiopulmonary bypass and cardioplegia.
    Type: Grant
    Filed: September 19, 2001
    Date of Patent: April 18, 2006
    Assignee: Heartport, Inc.
    Inventors: Wesley D. Sterman, Lawrence C. Siegel, Patricia E. Curtis, John H. Stevens, William S. Peters, Timothy R. Machold
  • Patent number: 7025722
    Abstract: The invention provides a system and method for performing less-invasive surgical procedures within a body cavity. In a preferred embodiment, the invention provides a system and method for isolating a surgical site such as an anastomosis between an internal mammary artery and a coronary artery in a thoracoscopic coronary artery bypass grafting procedure. The system comprises a foot (11) pivotally coupled to the distal end of a shaft (3) by a linkage (13). The foot has first and second engaging portions (15, 17) with contact surfaces for engaging a tissue surface. The engaging portions are movable between an open position, where the contact surfaces are separated by a gap, and a collapsed position, where the foot is configured for delivery through the percutaneous penetration.
    Type: Grant
    Filed: April 30, 2004
    Date of Patent: April 11, 2006
    Assignee: Heartport, Inc.
    Inventors: Mark A. Vierra, Alex T. Roth
  • Patent number: 6994669
    Abstract: The invention provides a stabilizer having a foot to stabilize a patient's heart. The stabilizer has a first foot which is larger than a second foot. The first foot has lateral surfaces which are used to retract other parts of the heart while contact surfaces stabilize the target artery.
    Type: Grant
    Filed: January 27, 2000
    Date of Patent: February 7, 2006
    Assignee: Heartport, Inc.
    Inventors: James R. Gannoe, Daniel M. Brounstein, Meir Moshe, Jan Komtebedde, David Evans, Andrew H. Hancock
  • Patent number: 6974434
    Abstract: An endovascular system for arresting a patient's heart and maintaining the patient on cardiopulmonary bypass. A venous cannula, venting catheter and an aortic occlusion device are all coupled together so that the blood drawn into each of these catheters may be fed to a pump. A manifold has valves which control flows through the venous cannula, venting catheter and aortic occlusion device. A blood storage element is also provided so that the amount of blood in the perfusion circuit may be varied if necessary. The blood storage element is preferably positioned in parallel with the pump so that the pump may be used to add and remove blood to and from the blood storage element.
    Type: Grant
    Filed: July 11, 2002
    Date of Patent: December 13, 2005
    Assignee: Heartport, Inc.
    Inventors: Craig P. Roberts, John M. Toomasian, Sylvia W. Fan
  • Patent number: 6939297
    Abstract: The invention provides a stabilizer having a foot to stabilize a patient's heart. The stabilizer has a first foot which is larger than a second foot. The first foot has lateral surfaces which are used to retract other parts of the heart while contact surfaces stabilize the target artery.
    Type: Grant
    Filed: November 6, 2001
    Date of Patent: September 6, 2005
    Assignee: Heartport, Inc.
    Inventors: James R. Gannoe, Daniel M. Brounstein, Meir Moshe, Jan Komtebedde, David Evans, Andrew H. Hancock
  • Patent number: 6913600
    Abstract: Devices and methods are provided for temporarily inducing cardioplegic arrest in the heart of a patient and for establishing cardiopulmonary bypass in order to facilitate surgical procedures on the heart and its related blood vessels. Specifically, a catheter based system is provided for isolating the heart and coronary blood vessels of a patient from the remainder of the arterial system and for infusing a cardioplegic agent into the patient's coronary arteries to induce cardioplegic arrest in the heart. The system includes an endoaortic partitioning catheter having an expandable balloon at its distal end which is expanded within the ascending aorta to occlude the aortic lumen between the coronary ostia and the brachiocephalic artery. Means for centering the catheter tip within the ascending aorta include specially curved shaft configurations, eccentric or shaped occlusion balloons and a steerable catheter tip, which may be used separately or in combination.
    Type: Grant
    Filed: September 25, 1998
    Date of Patent: July 5, 2005
    Assignee: Heartport, Inc.
    Inventors: Kirsten L. Valley, David W. Snow, Timothy C. Corvi, Brian S. Donlon, Stephen W. Boyd, Sylvia W. Fan, Alex T. Roth, William S. Peters, Richard J. Mueller, Jr., Hanson S. Gifford, III
  • Patent number: 6913601
    Abstract: A catheter system is provided for accessing the coronary ostia transluminally from a peripheral arterial access site, such as the femoral artery, and for inducing cardioplegic arrest by direct infusion of cardioplegic solution into the coronary arteries. In a first embodiment, the catheter system is in the form of a single perfusion catheter with multiple distal branches for engaging the coronary ostia. In a second embodiment, multiple perfusion catheters are delivered to the coronary ostia through a single arterial cannula. In a third embodiment, multiple perfusion catheters are delivered to the coronary ostia through a single guiding catheter. In a fourth embodiment, multiple catheters are delivered to the coronary ostia through a single guiding catheter which has distal exit ports that are arranged to direct the perfusion catheters into the coronary ostia.
    Type: Grant
    Filed: May 22, 2001
    Date of Patent: July 5, 2005
    Assignee: Heartport, Inc.
    Inventors: Frederick G. St. Goar, William S. Peters, Philip C. Evard, Stephen W. Boyd, Craig L. Adams, Richard L. Mueller, Jr., John H. Stevens
  • Patent number: 6902556
    Abstract: A method and device for occluding a patient's ascending aorta, maintaining circulation of oxygenated blood in the patient and delivering cardioplegic fluid to arrest the patient's heart. An aortic occlusion catheter has an occluding member for occluding the ascending aorta. The aortic occlusion catheter passes through a cannula. Delivery of oxygenated blood is accomplished through either the cannula of the aortic occlusion catheter. In another aspect of the invention, an arterial cannula having a curved or angled distal portion. An introducer straightens the distal portion for introduction into the patient. In still another aspect of the invention, an open-mesh stabilizer is used to stabilize a discoid occluding member.
    Type: Grant
    Filed: June 5, 2002
    Date of Patent: June 7, 2005
    Assignee: Heartport, Inc.
    Inventors: Kevin V. Grimes, Jan Komtebedde, Daniel C. Rosenman, Hanson S. Gifford, III, Michi E. Garrison, Wesley D. Sterman, David M. Taylor, A. Adam Sharkawy, Pinaki Ray
  • Patent number: 6899704
    Abstract: The invention provides devices and methods for performing less-invasive surgical procedures within an organ or vessel. In an exemplary embodiment, the invention provides a method of closed-chest surgical intervention within an internal cavity of a patient's heart or great vessel. According to the method, the patient's heart is arrested and cardiopulmonary bypass is established. A scope extending through a percutaneous intercostal penetration in the patient's chest is used to view an internal portion of the patient's chest. An internal penetration is formed in a wall of the heart or great vessel using cutting means introduced through a percutaneous penetration in an intercostal space in the patient's chest. An interventional tool is then introduced, usually through a cannula positioned in a percutaneous intercostal penetration.
    Type: Grant
    Filed: July 10, 2001
    Date of Patent: May 31, 2005
    Assignee: Heartport, Inc.
    Inventors: Wesley D. Sterman, Michi E. Garrison, Hanson S. Gifford, III, John H. Stevens, William S. Peters