Patents Assigned to Hisamitsu Pharmaceutical Co., Inc.
  • Patent number: 8664224
    Abstract: External preparations for athlete's foot treatment capable of enhancing patient's compliance and capable of reducing the symptom of rubefaction, comprising an anti-trichophyton drug mixed with at least one compound selected from among 1-menthol, menthol analogue compounds and bactericidal compounds.
    Type: Grant
    Filed: July 15, 2011
    Date of Patent: March 4, 2014
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Toshihiro Shirouzu, Youichi Kawamura, Hiroki Kawatsura, Mitsuhiko Tokunaga
  • Patent number: 8647664
    Abstract: A patch preparation having a backing layer and a drug layer laminated on the backing layer; wherein the drug layer contains an adhesive containing at least one compound selected from the group consisting of fentanyl and pharmaceutically acceptable salts thereof, polyisobutylene, and a silicon-containing polymer; and a mass ratio of the polyisobutylene and the silicon-containing polymer in the adhesive is 20:1 to 7:3.
    Type: Grant
    Filed: June 27, 2007
    Date of Patent: February 11, 2014
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Sachiko Honma, Tetsuro Tateishi
  • Publication number: 20140037710
    Abstract: A method for producing a patch including a support layer and an adhesive layer, comprising the step of forming the adhesive layer with use of an adhesive layer composition obtained by mixing an alkali metal diacetate, a drug, and a nonaqueous adhesive base such that the molar ratio between the drug and the alkali metal diacetate (the number of moles of the drug:the number of moles of the alkali metal diacetate) is from 1:0.5 to 1:15.
    Type: Application
    Filed: April 12, 2012
    Publication date: February 6, 2014
    Applicant: HISAMITSU PHARMACEUTICAL CO., INC.
    Inventors: Eiji Hashimoto, Isao Hagiwara, Yukihisa Naka, Hideharu Chono
  • Publication number: 20140037694
    Abstract: The present invention addresses the problem of providing a low-molecular weight adjuvant which can be administered safely without inducing skin irritation or the like by transdermal or transmucosal administration and is for efficiently enhancing the immunogenicity of an antigen. The present invention relates to an adjuvant for transdermal or transmucosal administration, containing at least one member selected from polyhydric alcohols and derivatives thereof including glycerol, glycerol derivatives and the like.
    Type: Application
    Filed: February 24, 2012
    Publication date: February 6, 2014
    Applicant: HISAMITSU PHARMACEUTICAL CO., INC.
    Inventors: Kumi Morimoto, Seiji Tokumoto
  • Patent number: 8580281
    Abstract: Provided is a medicated patch containing a medicinal agent and an adhesive base material and having an acid value of no greater than 28, where the medicinal agent is varenicline or a pharmaceutically acceptable salt of varenicline.
    Type: Grant
    Filed: February 9, 2009
    Date of Patent: November 12, 2013
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Kumi Morimoto, Akio Takeuchi, Takashi Yasukochi, Kaori Yamaguchi, Kenji Ishigaki
  • Patent number: 8574621
    Abstract: The present invention provides an adhesive patch for the treatment of tinea unguium intended to be applied once a day, comprising terbinafine and/or a pharmacologically acceptable salt thereof in an amount of 3 mg/cm2, wherein the adhesive patch is used so that the terbinafine concentration in nails may be 295±127 ng/mg and the terbinafine concentration in plasma may be 23 pg/mL or less, 8 weeks after the start of application, per cm2 of the patch size.
    Type: Grant
    Filed: February 7, 2011
    Date of Patent: November 5, 2013
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Arata Toshimitsu, Naoko Fujita, Toshihiro Kogure
  • Patent number: 8545873
    Abstract: A transdermal patch comprising a backing 2 and an adhesive layer 3 laminated on the backing 2, wherein the adhesive layer 3 comprises a rosin-based resin and petroleum resin as a tackifier, the total compounding amount of the rosin-based resin and the petroleum resin is in a range of 15% by mass to 50% by mass, and compounding amount of the petroleum resin is ? times by mass to 4 times by mass as that of the rosin-based resin.
    Type: Grant
    Filed: March 13, 2012
    Date of Patent: October 1, 2013
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Yasunori Takada, Koji Tanaka, Yasuhiro Ikeura
  • Patent number: 8524273
    Abstract: A transdermal absorption preparation having a support and a pressure-sensitive adhesive layer consisting of multiple layers, wherein the pressure-sensitive adhesive layer comprises a drug-retaining layer containing a drug and an acrylic pressure-sensitive adhesive and a skin adhesion layer containing a styrene-isoprene-styrene block copolymer. This preparation can continuously release bisoprolol at a constant concentration. Moreover, it can be easily produced.
    Type: Grant
    Filed: February 27, 2007
    Date of Patent: September 3, 2013
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Satoshi Amano, Sachiko Honma, Tetsuro Tateishi, Natsumi Kase
  • Publication number: 20130226098
    Abstract: An applicator 10 for applying a microneedle to a skin includes a tubular housing 11, a piston 20 which transmits a biasing force of a spring 40 to the microneedle, fixation means (a claw receiving portion 16 and claw portions 22a) for fixing the piston 20 against the biasing force of the spring 40 in the housing 11, and a cap 30 provided near a first end of the housing 11. A projecting portion 31 for releasing the piston 20 fixed by the fixation means is provided at a surface of the cap 30 facing the piston 20. The cap 30 is provided to be freely movable in an extending direction of the housing 11 such that the projecting portion 31 can contact the fixation means when the piston 20 is fixed by the fixation means.
    Type: Application
    Filed: October 6, 2011
    Publication date: August 29, 2013
    Applicant: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Seiji Tokumoto, Makoto Ogura, Kazuya Machida
  • Patent number: 8512742
    Abstract: Provided is a transdermal preparation, which is capable of long-term (1-day to 7-day) release of a basic drug from a preparation, continuously and at a consistent concentration; shows little reduction over time in the drug content, even if multiple drugs are contained in the preparation; and is produced by a simple process. The transdermal preparation comprises a substrate, and an adhesive layer containing a basic drug and a water-soluble polymer.
    Type: Grant
    Filed: April 30, 2010
    Date of Patent: August 20, 2013
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Satoshi Amano, Tomohiro Shinoda, Natsumi Kase
  • Publication number: 20130211353
    Abstract: Provided is a percutaneous absorption type formulation of a drug such as imidafenacin and silodosin, wherein stable absorption through the skin is realized. The percutaneous absorption type formulation containing a drug such as imidafenacin and silodosin further contains a transdermal absorption promoting agent, and fatty acid ester and/or fatty acid amide that further improve(s) the function of the transdermal absorption promoting agent.
    Type: Application
    Filed: October 26, 2011
    Publication date: August 15, 2013
    Applicant: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Arata Toshimitsu, Hisakazu Kurita
  • Publication number: 20130209799
    Abstract: A support film for tape which is used for a tape, the support film for tape includes: a film-shaped support formed of polyurethane; and a barrier layer which includes a water-soluble polymer compound and montmorillonite and is formed on one surface of the support. The support film for tape has a percentage content of the montmorillonite in the barrier layer is equal to or more than 2 percent by weight and equal to or less than 22 percent by weight.
    Type: Application
    Filed: June 15, 2011
    Publication date: August 15, 2013
    Applicants: HISAMITSU PHARMACEUTICAL CO., INC., MARUTO SANGYO CO., LTD., TOPPAN PRINTING CO., LTD.
    Inventors: Yasunori Takada, Takito Shima, Tetsurou Tateishi, Tsuguki Nishihara, Chiaki Yoshida, Atsushi Matsushima, Tsuyoshi Takamiya
  • Publication number: 20130211352
    Abstract: The purpose of the invention is to produce an imidafenacin-containing percutaneously absorbed preparation, wherein the drug not only is not allowed to crystallize but also has adequate skin penetration. The imidafenacin-containing percutaneously absorbed preparation comprises isostearic acid and a fatty acid ester, which function as crystallization-preventing agents.
    Type: Application
    Filed: October 26, 2011
    Publication date: August 15, 2013
    Applicant: Hisamitsu Pharmaceutical Co., Inc.
    Inventor: Hisakazu Kurita
  • Publication number: 20130195957
    Abstract: A patch comprising a support and an adhesive agent layer, wherein the adhesive agent layer comprises at least one selected from the group consisting of tolterodine acetate and salts thereof.
    Type: Application
    Filed: July 27, 2011
    Publication date: August 1, 2013
    Applicant: HISAMITSU PHARMACEUTICAL CO., INC.
    Inventors: Tomohiro Shinoda, Naoyuki Uchida, Yasunori Takada
  • Patent number: D692146
    Type: Grant
    Filed: January 14, 2011
    Date of Patent: October 22, 2013
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Sayaka Mochizuki, Yuichi Toyofuku
  • Patent number: D698928
    Type: Grant
    Filed: April 29, 2011
    Date of Patent: February 4, 2014
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Mitsutoshi Tsuruta, Kentaro Ishimatsu, Kiyotaka Takada
  • Patent number: D699344
    Type: Grant
    Filed: April 19, 2011
    Date of Patent: February 11, 2014
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Seiji Tokumoto, Makoto Ogura, Kazuya Machida
  • Patent number: D699363
    Type: Grant
    Filed: February 14, 2013
    Date of Patent: February 11, 2014
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Sayaka Mochizuki, Yuichi Toyofuku
  • Patent number: D699856
    Type: Grant
    Filed: February 14, 2013
    Date of Patent: February 18, 2014
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Sayaka Mochizuki, Yuichi Toyofuku
  • Patent number: D702119
    Type: Grant
    Filed: February 17, 2012
    Date of Patent: April 8, 2014
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Tatsuaki Sakai, Shigeo Kusumi