Abstract: The present invention relates to a process for the production of 3-mono or 3,5-disubstituted-4-acetoxystyrene wherein the 3- or 3,5-substitution is independently C.sub.1 to C.sub.10 alkyl, chlorine, bromine, iodine, --NO.sub.2, --NH.sub.2, or --SO.sub.3 H, a process for its polymerization, hydrolysis, and use in a variety of compositions.
Type:
Grant
Filed:
August 2, 1988
Date of Patent:
September 19, 1989
Assignee:
Hoechst Celanese
Inventors:
Mohammad Aslam, Richard Vicari, Ralph Dammel, Juergen Lingnau, Karl-Friedrich Doessel
Abstract: Derivatives of bicyclic aminocarboxylic acids, a process and intermediates for their preparation, and their use.The invention relates to compounds of the formula ##STR1## in which n is 1-3, R denotes acyl and R.sup.1 denotes an esterifying group or another carboxyl-protecting group, a process and intermediates for their preparation, and their use.
Type:
Grant
Filed:
December 2, 1987
Date of Patent:
September 19, 1989
Assignee:
Hoechst Aktiengesellschaft
Inventors:
Derek Barton, Pierre Potier, Yolande Herve, Josiane Thierry
Abstract: This invention provides novel isotropic condensation polymers which exhibit nonlinear optical response, and which have utility as a transparent optical component in optical light switch an light modulator devices.
Abstract: A process for producing cyanoethyl derivatives of hydroxyethylated polybenzimidazole is provided. The process comprises the steps of preparing an hydroxyethylated polybenzimidazole solution, mixing with that solution a base with a pka of at least 9 to form an hydroxyethylated polybenzimidazole anion and reacting the anion with acrylonitrile to produce a cyanoethyl derivative of the hydroxyethylated polybenzimidazole polymer. The derivative can be formed into ultrafilters, ion exchange membranes and for other such separatory articles.
Abstract: The present invention relates to a process for the production of 3-mono or 3,5-disubstituted-4-acetoxystyrene wherein the 3- or 3,5-substitution is independently C.sub.1 to C.sub.10 alkyl, chlorine, bromine, iodine, --NO.sub.2, --NH.sub.2, or --SO.sub.3 H, a process for its polymerization, hydrolysis, and use in a variety of compositions.
Type:
Grant
Filed:
February 21, 1989
Date of Patent:
September 19, 1989
Assignee:
Hoechst Celanese Corporation
Inventors:
Mohammad Aslam, Richard Vicari, Ralph Dammel, Juergen Lingnau, Karl-Friedrich Doessel
Abstract: A process is provided for preparing homopolyanhydrides or regularly alternating copolyanhydrides by condensing a bis(trimethylsilyl) ester of a dicarboxylic acid, e.g., an alkylenedicarboxylic acid such as sebacic acid or a bis(p-carboxyphenoxy)alkane such as 1,3-bis(p-carboxyphenoxy)propane, with a dicarboxylic acid chloride, e.g., an alkylenedicarboxylic acid chloride such as sebacoyl chloride or a phenylenedicarboxylic acid chloride such as terephthaloyl chloride or isophthaloyl chloride, to yield the polyanhydride and chlorotrimethylsilane as a by-product. The process may be carried out in the presence of a condensation catalyst, e.g., a highly ionized organic or inorganic fluoride, such as tetrabutylammonium fluoride.
Abstract: Novel 4-(benzisothiazol-3-yl)phenoxyacetic acid 1',1'-dioxides of the formula ##STR1## where X is hydrogen, halogen or loweralkyl; R.sub.1 is hydrogen or loweralkyl; R.sub.2 and R.sub.3 are each independently Cl, Br or CH.sub.3, and related compounds, methods for preparing same and methods of treatment by administering compositions containing such a compound are described. These compounds are useful as diuretics.
Abstract: In the device for evaluating test strips having individual test sections, which consist of a terminal, a work platform with holder for the test strips and a sensing head, a position mark 5 is arranged for each test section 9 on the side of the holder 13. On the work platform 15, the sensing head 14 is arranged so as to be capable of of traversing the test sections 9 and the position marks 5. The sensing head 14 is provided with light sources 6, which are directed towards the test sections 9, of different wavelength and with a light receiver and with at least one position detector 10 which is directed towards the position marks.
Abstract: There are provided novel homopolyanhydrides of carboxyaryloxyalkanoic acids, e.g. p-carboxyphenoxyacetic acid or 6-(p-carboxyphenoxy)hexanoic acid, capable of being formed into shaped articles. The homopolyanhydrides may be prepared by heating under reflux a solution of the acid monomer in acetic anhydride to form a mixed anhydride of the acid monomer and acetic acid and melt polycondensing the prepolymer by heating it under vacuum in an inert atmosphere. Due to their property of hydrolytic cleavage at predictable rates, the homopolyanhydrides are suitable as polymer matrices providing for the controlled release of an agent such as a drug.
Abstract: A process for the preparation of cefodizime of the formula ##STR1## wherein (a) a compound of the formula II (ATS) ##STR2## wherein R.sub.1 represents hydrogen or an aminoprotective group and A represents a hydrogen atom or one equivalent of an alkali metal or alkaline earth metal, of ammonium or of an organic nitrogen base, is first reacted with a compound of the formula IIIR--SO.sub.2 Halwherein R represents an optionally substituted alkyl, aryl or aralkyl radical and Hal represents a halogen atom, in an organic solvent and, if appropriate, in the presence of a base,(b) a compound of the formula I (TACS) ##STR3## in which A has the above meaning, is reacted with a silylating agent in an organic solvent and, if appropriate, in the presence of a base, and(c) the two products formed in (a) and (b) are reacted in their reaction solutions, and any protective group R.sub.1 present in the end product of the formula I is eliminated.
Type:
Grant
Filed:
December 1, 1986
Date of Patent:
September 19, 1989
Assignee:
Hoechst Aktiengesellschaft
Inventors:
Ottmar Jaenicke, Hans Wagner, Manfred Worm
Abstract: There are described compounds of the formula: ##STR1## where, X is hydrogen, loweralkyl, loweralkoxy or halogen;Y is hydrogen, loweralkyl or halogen;Z is hydrogen, loweralkyl or halogen;R is hydrogen, loweralkyl, loweralkenyl, loweralkylcarbonyl, dimethylaminoloweralkyl or ##STR2## m being an integer of 1 to 6, with the proviso that when R is loweralkenyl the double bond is not alpha to the nitrogen atom;which compounds are useful analgesic, anticonvulsant and antidepressant agents, and for treating various memory dysfunctions characterized by decreased cholinergic function such as Alzheimer's disease.
Type:
Grant
Filed:
December 27, 1988
Date of Patent:
September 19, 1989
Assignee:
Hoechst-Roussel Pharmaceuticals, Inc.
Inventors:
Richard C. Effland, Joseph T. Klein, Larry Davis, Gordon E. Olsen
Abstract: The instant invention involves a process for preparing carboxylic acid esters which comprises coreacting a carboxylic acid and an aliphatic mono or polyol by maintaining one of the reactants in a reactor at elevated temperatures and adding the other reactant to the reactor over a period of time. By employing this process esterification times are significantly reduced.
Type:
Grant
Filed:
March 7, 1988
Date of Patent:
September 19, 1989
Assignee:
Hoechst Celanese Corp.
Inventors:
Thomas M. Powanda, Robert H. Imes, George L. Collins
Abstract: A method for treating paper or other fibrous materials to improve the holdout characteristics of printing inks, lacquers and coating compositions. The method involves the application of an organophilic complex of(a) a water-insoluble hydrated cation-exchangeable film-forming smectitic layered silicate having an ion exchange capacity of at least 50 milliequivalents/100 g and(b) an organic radical derived from an onium compound attached thereto.The organophilic complex forms a barrier layer by reaction with the organic solvent contained in the printing ink, lacquer or other coating composition.
Abstract: There are disclosed compounds having the formula ##STR1## where n is 1, 2 or 3;X is hydrogen, loweralkyl, loweralkoxy, halogen, hydroxy, nitro or trifluoromethylR.sub.1 and R.sub.2 are each independently hydrogen, lower alkyl or arylloweralkyl, but both may not be arylloweralkyl simultaneously;R.sub.3 and R.sub.4 are each independently hydrogen, lower alkyl, arylloweralkyl, formyl or lower alkylcarbonyl, or alternatively the group --NR.sub.3 R.sub.4 taken as a whole constitutes ##STR2## stereo isomers thereof and pharmaceutically acceptable acid addition salts thereof, which are useful for the treatment of various memory dysfunctions characterized by decreased cholinergic function, such as Alzheimer's disease.
Abstract: This invention provides novel polysiloxane polymers which exhibit nonlinear optical response, and which have utility as a transparent optical component in electrooptic light modulator devices.
Type:
Grant
Filed:
January 24, 1986
Date of Patent:
September 19, 1989
Assignee:
Hoechst Celanese Corp.
Inventors:
Ronald N. DeMartino, Hyun-Nam Yoon, James B. Stamatoff, Alan Buckley
Abstract: Polyesters of 4,4'bis[2-(4-hydroxyphenyl)hexafluoroisopropyl]diphenyl ether having high transparency, high solvent solubility and excellent melt processability are prepared. They possess high thermal and radiation stability and are useful in the preparation of protective films, protective paints, films, fibers, diffusion membranes and shaped articles where high service temperature and radiation resistance are desired.
Abstract: This invention provides novel isotropic acrylic copolymers which exhibit nonlinear optical response, and which have utility as a transparent optical component in optical light switch and light modulator devices.
Abstract: There are disclosed compounds of the formula, ##STR1## where X and Y are each independently hydrogen, loweralkyl, halogen or trifluoromethyl; Z is hydrogen or 2- or 3-Cl, Br, I, CHO or CH.dbd.CR.sub.1 R.sub.2 where R.sub.1 and R.sub.2 are each independently hydrogen or loweralkyl; R is hydrogen, ##STR2## where n is 1, 2 or 3, R.sub.3 is loweralkyl, and R.sub.4 is hydrogen or loweralkyl, or alternatively the group --NR.sub.3 R.sub.4 as a whole is ##STR3## where R.sub.6 is loweralkyl, ##STR4## and R.sub.7 is loweralkyl or ##STR5## R.sub.8 being hydrogen, loweralkyl, halogen, trifluoromethyl or methoxy; and R.sub.5 is hydrogen, loweralkyl or arylloweralkyl.
Abstract: A process is described for recovering gallium from a basic aqueous sodium aluminate solution by means of liquid-liquid extraction, in which process the aqueous sodium aluminate solution to be extracted is brought into contact with a water-insoluble extraction solution, comprising essentially a water-insoluble substituted hydroxyquinoline and a selected water-insoluble aldoxime as extractant, and a water-insoluble organic solvent for the extractant, the organic phase is separated off from the aqueous phase after bringing the two solutions into contact, and the gallium is recovered from the organic phase.
Abstract: In one embodiment this invention provides a frequency doubling optical waveguide consisting of a substrate-supported polymeric thin film which exhibits second order nonlinear optical response, and which has a periodic structure for quasi-phase matching of propagating laser wave energy.In a preferred embodiment the waveguide has a two-dimensional channel structure for intensified single mode wave transmission.