Abstract: A thermal management system for an enclosure containing electrical components includes a thermoelectric cooling unit for controlling temperature inside the enclosure and a controller for the cooling unit, the controller being configured so that it can be installed within and protected by the enclosure, rather than requiring its own separate secure enclosure. The controller can further be installed within a housing of the thermoelectric cooling unit, which housing does not increase the footprint of the cooling unit. The housing can include a cover that separates the space within the housing into two compartments, with the controller mounted at an angle that allows the controller to fit within one of the compartments and under the cover.

Abstract: The present invention provides spiro-oxazolones, which act as V1a receptor modulators, and in particular as V1a receptor antagonists, their manufacture, pharmaceutical compositions containing them and their use as medicaments. The present compounds are useful as therapeutics acting peripherally and centrally in the conditions of inappropriate secretion of vasopressin, anxiety, depressive disorders, obsessive compulsive disorder, autistic spectrum disorders, schizophrenia, aggressive behavior and phase shift sleep disorders, in particular jetlag.

Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R1?, R2, R3, R4 are as defined herein, compositions including the compounds and methods of using the compounds.

Abstract: A float drain for an enclosure can include a basket to collect liquid from the enclosure, a sealing structure surrounding an outlet of the basket, and a float configured to seat against the sealing surface to prevent fluid flow out of the outlet and to rise off of the sealing surface due to buoyancy forces as the liquid collects in the basket. The float drain can include other features, including: ribs or other protrusions extending into an interior are of the basket to space the float apart from an inner wall of the basket; an angled orientation of the sealing surface; and a trough, at least partly defined by the sealing structure, to collect debris.

Abstract: The present inventions relate generally to compositions, kits, and methods for the treatment of stress-related disorders, including but not limited to post-traumatic stress disorder.

Abstract: Embodiments of the invention provide a rod guide for mounting a latch rod to an enclosure. A guide member can include a guide-member support surface and a guide opening to receive the latch rod. A base member can include a base-member support surface. The base member can support the guide member with the guide opening at different distances from the surface of the enclosure when the guide-member support surface is seated on the base-member support surface with the guide member disposed at different respective rotational orientations relative to the base member.

Abstract: Herein are reported humanized anti-IL-1beta antibodies that are humanized variants of the murine anti-IL-1beta antibody H34. A specific humanized antibody comprises (a) a HVR-H1 comprising the amino acid sequence of SEQ ID NO: 25, (b) a HVR-H2 comprising the amino acid sequence of SEQ ID NO: 27, and (c) a HVR-H3 comprising the amino acid sequence of SEQ ID NO: 28.

Abstract: Embodiments of the disclosure provide an encapsulated compressor overload, an encapsulated compressor relay start, an encapsulated head pressure control switch and a wiring diagram for a circuit for air conditioning units which prevent gases from being ignited by means of encapsulating sparking components, use of solid-state switching devices, and/or wiring circuits in such a way that open contacts do not contain enough energy to produce a spark capable of igniting the atmosphere.

Abstract: The invention relates to a pump device for operating vacuum drainage systems and for pumping sewage, in particular on watercrafts. This pump device comprises a drive device having a drive shaft that comprises a first shaft end and a second shaft end and can be rotated by means of the drive device. The pump device further comprises a centrifugal pump which has at least one impeller that is connected in a torque-proof manner to the drive shaft in the region of the first shaft end.

Abstract: The invention relates to bispecific antibodies comprising a first antigen-binding site that specifically binds to PD1 and a second antigen-binding site that specifically binds to TIM3, in particular to bispecific antibodies, wherein the bispecific antibody binds to TIM3 with a lower binding affinity when compared to the binding to PD1. The invention further relates to methods of producing these molecules and to methods of using the same.

Abstract: The disclosure relates to a portable fuel container system which can facilitate extracting substantially all of the contents contained therein, without having to physically manipulate the container to do so, thereby minimizing spillage and waste. Embodiments of the fuel container system can include a fuel container enclosing a fluid cavity and a fluid dispenser. A collection channel may be recessed in the base section of the container and configured to gravitationally draw fluid to an end of the channel having an aperture, which forms a low point of the fluid cavity. A fluid dispenser can be coupled to the aperture and be in fluid communication with the cavity. The dispenser can include a valve and flexible conduit, allowing the user to position the dispenser to a desired location before activating the flow of fluid.

Abstract: The present invention relates to compounds of formula (I): or pharmaceutically acceptable salts thereof, wherein L and R1 to R5 are as described herein, as well as processes for their manufacture, pharmaceutical compositions comprising them, and their use as medicaments.

Abstract: The present invention relates to compounds according to Formula (II): or a stereoisomer, tautomer or pharmaceutically acceptable salt or ester thereof, wherein A, R1 and R2 are defined herein. Also described are pharmaceutically acceptable compositions of Formula (II) compounds as well as methods for utilizing the compounds of Formula (II) and the pharmaceutically acceptable compositions of Formula (II) compounds as antibacterial agents and ?-lactamase inhibitors, useful in the treatment of infectious diseases.

Abstract: A method for determining whether reconstitution of a solution in a container is completed comprises the steps of: selecting a predetermined amount of a solid substance and a predetermined amount of a liquid solvent from which the reconstituted solution is to be prepared, preparing a solution by solving the predetermined amount of the solid substance in the predetermined amount of the liquid solvent, measuring the impedance (Z) or the resistance (R) of the solution, determining whether the change of the measured impedance (Z) or the resistance (R) within a measuring time interval of a predetermined duration is below a defined threshold, and determining that reconstitution of the solution is completed when the change of the measured impedance (Z) is below the defined threshold.

Abstract: The invention relates to a carbon brush arrangement for connection to an electric motor, comprising at least one carbon brush (17, 18) connected to a connection means (29) provided with a plastic connection housing (32) via a connection conductor (15, 16) provided with a plastic sheath (24, 25), said plastic sheath (24, 25) consisting of perfluoroalkoxy polymer (PFA) in at least a region of transition (33, 34) to the connection housing (32).

Abstract: The invention provides novel compounds having the general formula: wherein R1, R2, R3, R4, R5, R6, W1, W2, W3, A and X are as described herein, compositions including the compounds and methods of using the compounds for the treatment and prophylaxis of respiratory syncytial virus infection.