Patents Assigned to Hong Kong University of Science and Technology
  • Patent number: 9315465
    Abstract: AIE (aggregation-induced emission)-active TPE derivatives, TPE-TPP, TPE-MitoR and TPE-IQ are contemplated. These specific TPE derivatives are useful as fluorescent agents for mitochondrial imaging and as apoptosis inducers. Possessing high specificity to mitochondria, superior photostability and appreciable tolerance to microenvironment change, TPE derivatives are well-suited imaging agents for mitochondrial targeting and morphological change tracking. Because of their synthetic flexibility, TPE derivatives can be further modified as dual-functional probes for an array of applications such as sensing of ROS, metal ions, or pH change in mitochondria.
    Type: Grant
    Filed: January 27, 2014
    Date of Patent: April 19, 2016
    Assignee: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Benzhong Tang, Yuning Hong, Sijie Chen, Wai Tung Leung, Engui Zhao, Haiqin Deng
  • Patent number: 9314421
    Abstract: The present invention provides a novel system and method for transscleral delivery of therapeutic agents, including macromolecules, into a target site in intrascleral space using ultrasound. Advantageously, the present invention not only significantly enhances transscleral diffusivity of macromolecular therapeutic agents, but also causes little damages to ocular tissues and structure.
    Type: Grant
    Filed: March 4, 2010
    Date of Patent: April 19, 2016
    Assignee: The Hong Kong University of Science and Technology
    Inventors: Ying Chau, Chi Yeung Cheung, Yu Yu
  • Patent number: 9299863
    Abstract: A solar cell photovoltaic device using ultrathin films of polycrystalline silicon and deep uneven surface structures is disclosed. According to one embodiment, the uneven structures include one or more pits having a depth of at least 10 microns. According to another embodiment, the uneven structures include one or more cones or columns having a height or at least 10 microns. Because the unevenness of the structures, the photovoltaic device is able to use a very thin layer of polycrystalline silicon to effectively trap and absorb light.
    Type: Grant
    Filed: May 7, 2009
    Date of Patent: March 29, 2016
    Assignee: The Hong Kong University of Science and Technology
    Inventors: Hoi Sing Kwok, Zhiguo Meng, Man Wong
  • Patent number: 9298050
    Abstract: A liquid crystal cell structure comprising transparent terahertz (THz) windows, alignment layers, protective layers, in-plane electrodes, out-of-plane electrodes, and a liquid crystal (LC) layer. The in-plane electrodes generate in-plane electric fields that are parallel to the liquid crystal layer and the out-of-plane electrodes generate out-of-plane electric fields that are perpendicular to the liquid crystal layer. The in-plane and out-of-plane electrodes have wire-grid patterns to increase THz wave transmission efficiency. The wire-grid patterned electrodes are transparent to THz waves that have parallel polarization compared to a grating vector of the wire grid pattern and are opaque to THz waves of perpendicular polarization. These two electrodes are controlled independently to tune the optical properties of the LC and improve the operating speed of THz LC devices.
    Type: Grant
    Filed: August 30, 2012
    Date of Patent: March 29, 2016
    Assignees: The Hong Kong University of Science and Technology, The Chinese University of Hong Kong
    Inventors: Emma MacPherson, Hongkyu Park, Fan Fan, Vladimir Grigorievich Chigrinov, Edward Philip John Parrott
  • Patent number: 9287344
    Abstract: Providing for a monolithic magnetic induction device having low DC resistance and small surface area is described herein. By way of example, the magnetic induction device can comprise a substrate (e.g., a semiconductor substrate) having trenches formed in a bottom layer of the substrate, and holes formed in the substrate between the trenches and an upper layer of the substrate. Additionally, the magnetic induction device can comprise a conductive coil embedded or deposited within the trenches. The magnetic induction device can further comprise a set of conductive vias formed in the holes that electrically connect the bottom layer of the substrate with the upper layer. Further, one or more integrated circuit components, such as active devices, can be formed in the upper layer, at least in part above the conductive coil. The vias can be utilized to connect to integrated circuit components with the conductive coil, where suitable.
    Type: Grant
    Filed: August 23, 2011
    Date of Patent: March 15, 2016
    Assignee: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Johnny Kin On Sin, Rongxiang Wu, Ron Shu Yuen Hui
  • Patent number: 9286691
    Abstract: The subject disclosure relates to motion estimation and compensation of feature-motion decorrelation. In an aspect, coupled filtering can be employed to solve feature-motion decorrelation problems. In further aspects, a linear convolution model can be employed to model image variation caused by motion, and an image before motion and a warped image after motion can be filtered with a pair of filters having motion parameters shared with a tissue motion model. Compensation of feature-motion decorrelation in ultrasound images demonstrates various aspects of the subject disclosure.
    Type: Grant
    Filed: April 12, 2010
    Date of Patent: March 15, 2016
    Assignee: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Weichuan Yu, Tianzhu Liang
  • Patent number: 9283204
    Abstract: This invention relates to extracts and refined fractions of a traditional Chinese medicinal herb, Alpinia officinarum (AO), components thereof, and the use of such compounds and compositions to treat neurodegenerative or neuropathological conditions or to inhibit aggregation of a-synuclein.
    Type: Grant
    Filed: August 10, 2011
    Date of Patent: March 15, 2016
    Assignee: The Hong Kong University of Science and Technology
    Inventors: Nancy Yuk Yu Ip, Kenny Ka Kin Chung, Fanny Chui Fun Ip, Guangmiao Fu
  • Patent number: 9279806
    Abstract: Compounds that exhibit aggregation induced emission (AIE), and more particularly to water-soluble conjugated polyene compounds that exhibit aggregation induced emission. The conjugated polyene compounds can be used as bioprobes for DNA detection, G-quadruplex identification, and potassium-ion sensing. The polyenes also can be utilized as an external fluorescent marker to study conformational structures, to monitor folding processes of label-free oligonucleotides with G-rich strand sequences, and to visualize DNA bands in PAGE assay. The polyenes have applications in high-throughput anticancer drug screening and are useful for the development of efficient anti-cancer drugs. Furthermore, the present subject matter can also be used to monitor fibrillation of amyloid proteins and to facilitate the storage and delivery thereof.
    Type: Grant
    Filed: February 4, 2014
    Date of Patent: March 8, 2016
    Assignee: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Benzhong Tang, Yuning Hong, Sijie Chen, Tsz Kin Ryan Kwok, Wai Tung Leung
  • Publication number: 20160038599
    Abstract: The present invention provides compositions, and related kits and methods, for formation of hydrogels. The compositions comprise one or more chemically crosslinkable agents dissolved in an aqueous solution to form a precursor solution. The chemically crosslinkable agents useful in the present invention are selected from polymers modified with a molecule selected from acrylate, maleimide, vinylsulfone, N-hydroxysuccinimide, aldehyde, ketone, carbodiimide, carbonate, iodoacetyl, mercaptonicotinamide, quinone, thiol, amine, and combinations thereof. The precursor solution is characterized as being in an aqueous form at a non-physiologic physical-chemical condition and undergoing gelation when in contact with another fluid or body at a physiologic physical-chemical condition.
    Type: Application
    Filed: April 17, 2014
    Publication date: February 11, 2016
    Applicant: Hong Kong University of Science and Technology
    Inventors: Ying Chau, Yu Yu, Jieying Zhong
  • Publication number: 20160026926
    Abstract: The invention provides a clothing matching system and a method for generating at least an outfit suggestion comprising the steps of determining a colour classification of a user, providing a plurality of articles of clothing, selecting a dress code based on the user preference and generating at least one outfit suggestion based on the colour classification of the user, the plurality of clothing items and the selected dress code.
    Type: Application
    Filed: November 12, 2013
    Publication date: January 28, 2016
    Applicants: Singapore University of Technology and Design, Hong Kong University of Science and Technology, University of California, Los Angeles
    Inventors: Sai-Kit Yeung, Tony Chan, Lap-Fai Yu, Demetri Terzopoulos
  • Publication number: 20160023202
    Abstract: An impregnated and activated ion exchange material prepared by a process is provided that includes: impregnating an ion exchange precursor material, wherein impregnation of the ion exchange precursor material includes reacting the ion exchange precursor material with an impregnator solution, thereby increasing the surface area and the hydrophilicity of the ion exchange precursor material; activating the impregnated ion exchange precursor material to increase the porosity of the impregnated ion exchange precursor material, wherein the ion exchange precursor material comprises at least one of nonmetallic printed (NMP) circuit board, amorphous aluminosilicate, or mixtures thereof. In other aspects, a method for fabricating an ion exchanger and a method for removing heavy metal ions from a solution are provided.
    Type: Application
    Filed: March 12, 2014
    Publication date: January 28, 2016
    Applicant: The Hong Kong University of Science and Technology
    Inventors: Pejman Hadi Myavagh, Gordon McKay
  • Patent number: 9237646
    Abstract: A conductive thin film device includes a substrate and a thin film structure applied to the substrate. The thin film structure is applied as a first layer and forms a one-dimensional nanomaterial networked layer deposited on the substrate. A coating layer overlays the one-dimensional nanomaterial networked layer and can be made from graphene or graphene oxide. The coating layer at least partially covers the nanomaterial networked layer, thereby forming the device as a double-layer structure.
    Type: Grant
    Filed: May 10, 2013
    Date of Patent: January 12, 2016
    Assignee: The Hong Kong University of Science and Technology
    Inventors: Matthew Ming Fai Yuen, Xinfeng Zhang, Wayman Ngai Man Wong
  • Patent number: 9231709
    Abstract: Systems, methods, and apparatus are described that employ specially designed interference patterns to build an in-band side channel without degrading the effective throughput of the main channel. A first device (100) includes a control component (130) that generates control information and an interference component (140) that transmits the control information (450) through emission of patterned interference data concurrently while other users are transmitting other data (420). A second device (300) receives the patterned interference data and the other data via a single antenna (350) and decodes the patterned interference data to extract the control data (450). The first device (100) transmits the other data (420) on a side channel (440) that resides in the same spectrum as the main channel (410) in which the other data (420) is emitted. The first device (100) encodes the interference patterns such that the control data (450) can be safely transmitted and extracted without effecting other data transmission.
    Type: Grant
    Filed: March 30, 2011
    Date of Patent: January 5, 2016
    Assignee: The Hong Kong University of Science and Technology
    Inventors: Kaishun Wu, Qian Zhang, Lionel Ming Shuan Ni
  • Patent number: 9228949
    Abstract: Pyridine-containing polyenes and their applications as metal ion sensors. These polyenes are practically nonluminescent in the solution state but become highly emissive as nanoparticle suspensions in aqueous solutions or thin films in the solid state, due to aggregation-induced emission (AIE). The nanoaggregates of these compounds can work as “turn-off” fluorescent chemosensors for metal ions and display different fluorescence responses to various metal ions. For example, a characteristic red shift in the emission spectra is observed with a terpyridine-containing luminogen in the presence of Zn2+. However, the terpyridine-containing luminogen displays a magenta color upon selectively binding with Fe2+. This allows easy identification of both Zn2+ and Fe2+ ions in aqueous media. The function of the polyenes can be easily tuned by altering the substituent groups. Due to their AIE properties, these polyenes can be used in aqueous solutions and in solid substrates for metal sensing.
    Type: Grant
    Filed: September 4, 2012
    Date of Patent: January 5, 2016
    Assignee: The Hong Kong University of Science and Technology
    Inventors: Benzhong Tang, Yuning Hong, Wai Tung Leung
  • Patent number: 9217733
    Abstract: A method and system for detecting residual poison in human body are provided. Using the disclosed HPLC-Chip-mass spectrometry (MS)/MS and/or HPLC-MS/MS method to detect the residual poison, the method of the present invention mainly includes sample preparation, liquid chromatography and mass spectrometry. The method of the present invention has advantages of low sample size, high specificity, low detection limit, high sensitivity, low cost, high accuracy and stability, etc.
    Type: Grant
    Filed: November 5, 2010
    Date of Patent: December 22, 2015
    Assignee: The Hong Kong University of Science and Technology
    Inventors: Karl Wah Keung Tsim, Tina Tingxia Dong, Kevin Yue Zhu, Ka Wing Leung, Tiejie Wang
  • Patent number: 9214568
    Abstract: A thin film transistor includes: a source region; a drain region; and a polycrystalline thin film active channel region connected to the source region and the drain region, the active channel region comprising grains and being doped with a two-dimensional pattern comprising a plurality of doped regions, the plurality of doped regions each comprising at least portions of a plurality of the grains and at least one grain boundary.
    Type: Grant
    Filed: December 12, 2013
    Date of Patent: December 15, 2015
    Assignee: The Hong Kong University of Science and Technology
    Inventors: Hoi Sing Kwok, Meng Zhang, Shuming Chen, Wei Zhou, Man Wong
  • Patent number: 9200121
    Abstract: A poly(siloxane-diphenylbutadiyne) exhibiting thermosetting properties, a highly tunable glass transition temperature (Tg), and very high thermal and thermo-oxidative stability. In one embodiment, the poly(siloxane-diphenylbutadiyne) is a poly(tetrasiloxane-diphenylbutadiyne). The present subject matter also relates to a method of synthesizing the poly(tetrasiloxane-diphenylbutadiyne).
    Type: Grant
    Filed: April 7, 2013
    Date of Patent: December 1, 2015
    Assignee: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Benzhong Tang, Jie Li, Rongrong Hu, Wing Yip Lam
  • Patent number: 9191060
    Abstract: Signal processing, data encoding and/or decoding techniques are applied in a dictionary system. A dictionary is generated as a function of time shift and phase shift distortion. Atoms of the dictionary can be determined. Further, parameters of the dictionary can be flexibly chosen. In one aspect, signals can be processed as a function of the dictionary.
    Type: Grant
    Filed: April 16, 2013
    Date of Patent: November 17, 2015
    Assignee: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventor: Maosheng Xiong
  • Patent number: 9166197
    Abstract: The invention provides an organic light emitting diode (OLED), having a substrate, an anode layer of silver or gold, wherein the anode layer is treated with CF4 plasma to enhance the hole injection of the semitransparent anode layer.
    Type: Grant
    Filed: June 29, 2006
    Date of Patent: October 20, 2015
    Assignee: The Hong Kong University of Science and Technology
    Inventors: Hoi Sing Kwok, Man Wong, Huajun Peng, Jiaxin Sun
  • Patent number: 9166928
    Abstract: Systems and methods are presented relating to a three stage crossbar based switching system and a scheduling method for transmission of data packets and associated request and grant tokens. The first stage and third stage portions of the switching system contain TDM crossbars, which are interconnected by a middle stage set of crossbars. In an embodiment, the system switching module is a m×m crossbar switch comprising m inputs and m outputs. The switch has a size m2×m2 formed from m×m crossbar modules. Scheduling of data packet servicing is on a frame by frame basis relating to selection based on port addresses and port address groups. Further, time slot interchange is utilized to address time slot mismatch.
    Type: Grant
    Filed: September 27, 2012
    Date of Patent: October 20, 2015
    Assignee: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventor: Chin Tau Lea