Patents Assigned to Horiba ABX SAS
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Publication number: 20110167029Abstract: The invention provides a method for use in an automated biological liquid analysis machine that measures at least four physical parameters for each cell detected, the method both performing classification, by discrimination and enumeration, into a set of at least three cell classes and also representing them.Type: ApplicationFiled: August 5, 2009Publication date: July 7, 2011Applicant: HORIBA ABX SASInventor: Sebastien Raimbault
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Patent number: 7963152Abstract: The invention relates to a modular device for implementation in a biological fluid analysis system. It comprises functional modules, each comprising a support for supporting hydraulic components, the support including at least two plates having etched therein circuits that enable channels to be defined when the two plates are assembled side by side. According to the invention, said functional modules comprise at least a preparation first functional module for preparing a fluid for analysis and supporting at least one dilution vessel, and an injection second functional module for injecting the fluid prepared in said dilution vessel towards an analysis unit, said first and second modules being connected to one another.Type: GrantFiled: September 19, 2006Date of Patent: June 21, 2011Assignee: Horiba ABX SASInventors: Roger Le Comte, Guilhem Couderc, Didier Cremien, Paul Moreno
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Publication number: 20110089340Abstract: The invention relaters to a device (100) for biological analysis by measurement of photoluminescence in a fluid in a measurement tank (111). This device (100) comprises at least two light sources (121, 131) adapted to emit in different spectral areas respectively appropriate for measurement of absorption and fluorescence, and a sensor device (140) comprising a sensor (141), an optical system (142), and filter means (144), which three elements are mutualized in accordance with the invention to enable absorption and/or fluorescence to be measured. In accordance with the invention the internal gain of the sensor (141) is configurable to enable the fluorescence and absorption measurements to be executed sequentially.Type: ApplicationFiled: June 25, 2009Publication date: April 21, 2011Applicant: HORIBA ABX SASInventors: Benoit Merchez, Patrick Brunel, Philippe Nerin
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Patent number: 7858032Abstract: A device including a pre-analytical module provided with at least one tube stirrer for homogenizing blood and preventing clot formation and disposed on a line for single-tube transfer between an area for storing analyzable tubes, and at least one unitary operating whole blood analyzer and automatic tube-loading/unloading device arranged between the tube stirrer and the single-tube transfer line. The device is suitable for blood analyzers.Type: GrantFiled: March 11, 2005Date of Patent: December 28, 2010Assignee: Horiba ABX SASInventors: Roger Le Comte, François Dupoteau
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Patent number: 7777869Abstract: The invention concerns a device (DA) for analyzing microscopic elements, comprising firstly a measuring space (CM) for microscopic elements to be analyzed, secondly at least one source (S) delivering conjugated rays at the measuring space (CM), having at least two different analyzing wavelengths and designed to interact with the microscopic elements in the measuring space (CM) to form interacting rays, thirdly coding means (M) for encoding the rays upstream of the measuring space (CM) with different codes, fourthly optical filtering means (FO) for selectively filtering the interacting rays of fluorescence and/or diffusion depending on their wavelength, fifthly detecting means (DE, DF) for transforming into electric signals part at least of the interacting rays from the measuring space (CM), and sixthly analyzing means (MA) including decoding means (DRE, DRF) for decoding the electric signals to enable data representing the analyzed microscopic elements to be determined.Type: GrantFiled: April 14, 2006Date of Patent: August 17, 2010Assignee: Horiba ABX SASInventors: Philippe Nerin, Didier Lefevre
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Patent number: 7768691Abstract: A dedicated polychromatic light generating device including optical pumping devices used to deliver radiation with at least two different excitation wavelengths and a light-guiding device used to deliver polychromatic light at an output when excited by the radiation in a non-linear interaction regime.Type: GrantFiled: March 8, 2005Date of Patent: August 3, 2010Assignees: Horiba ABX SAS, Universite de Limoges, Centre National de la Recherche Scientifique CNRSInventors: Philippe Nerin, Pierre-Alain Champert, Sébastien Fevrier, Philippe Roy, Vincent Couderc, Philippe Leproux, Ludovic Grossard
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Patent number: 7724371Abstract: An optical device for examining a fluid including a measuring space including a compulsory passage for the fluid to be examined, at least one source delivering a selected light to an optical illuminator serving to collect at least part of the light having traversed the compulsory passage and to deliver the selected light to analyze the collected light so as to deliver signals representing data borne by the collected light. The optical illuminator includes a first light guide including one end, opposite the source, and configured to deliver the light, derived from the source, in accordance with a selected geometry to illuminate the compulsory passage in a substantially uniform manner and under a substantially constant intensity.Type: GrantFiled: November 7, 2005Date of Patent: May 25, 2010Assignee: Horiba ABX SASInventors: Philippe Nerin, Paul Moreno, Didier Cremien
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Publication number: 20100062521Abstract: A subject of the invention is a packaging device for automated biological analyses, characterized in that it comprises the sample(s) to be analyzed, reagent(s), and the information necessary to carry out one (or more) analyse(s) of a sample of biological liquid and a location intended to receive the waste products from the analysis and optionally to treat them.Type: ApplicationFiled: May 15, 2007Publication date: March 11, 2010Applicant: Horiba ABX SASInventors: Sylvie Veriac, Valérie Paya-Souquet, François Dupoteau
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Publication number: 20090142844Abstract: The present invention relates to a method of preparing analyses of total blood samples and to a device that is useful for implementing the method, said samples being conserved in tubes including at least one identification means for identifying the sample, the device comprising: at least one compartment constituting a said storage zone for storing said tubes before and after analysis; and at least one said read means for reading said identification means of said tubes; and at least one preparation zone for preparing said blood samples prior to analysis and including means for verifying and/or treating said tubes containing said samples, and in particular at least one agitator means for agitating said tubes; and at least one access zone giving access to at least one automatic analyzer of total blood, said access zone enabling a said tube to be placed in said analyzer; and robotic gripper and displacement means controlled by an automatic controller and suitable for taking hold of and replacing said tubes indType: ApplicationFiled: July 4, 2006Publication date: June 4, 2009Applicant: HORIBA ABX SASInventor: Roger Le Comte
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Publication number: 20080283754Abstract: The invention concerns a device (DA) for analyzing microscopic elements, comprising firstly a measuring space (CM) for microscopic elements to be analyzed, secondly at least one source (S) delivering conjugated rays at the measuring space (CM), having at least two different analyzing wavelengths and designed to interact with the microscopic elements in the measuring space (CM) to form interacting rays, thirdly coding means (M) for encoding the rays upstream of the measuring space (CM) with different codes, fourthly optical filtering means (FO) for selectively filtering the interacting rays of fluorescence and/or diffusion depending on their wavelength, fifthly detecting means (DE, DF) for transforming into electric signals part at least of the interacting rays from the measuring space (CM), and sixthly analyzing means (MA) including decoding means (DRE, DRF) for decoding the electric signals to enable data representing the analyzed microscopic elements to be determined.Type: ApplicationFiled: April 14, 2006Publication date: November 20, 2008Applicant: HORIBA ABX SASInventors: Philippe Nerin, Didier Lefevre
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Publication number: 20080124745Abstract: The invention concerns a method for differentiating and counting cellular components present in a biological fluid sample comprising a primary cytological analysis step typically implemented by a flow cytometry equipment (1) to obtain a set of primary results enabling the set of cellular components of the sample to be differentiated and counted in different populations; and a complementary step of cytological analysis of a particular type of cellular components, based on an identified cellular peculiarity, to obtain complementary results enabling at least one cell population or subpopulation of the sample to be differentiated and counted for identification of said cellular peculiarity. The invention is applicable in particular to hematological analyses.Type: ApplicationFiled: July 6, 2005Publication date: May 29, 2008Applicant: HORIBA ABX SASInventor: Didier Lefevre
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Publication number: 20070216989Abstract: A dedicated polychromatic light generating device including optical pumping devices used to deliver radiation with at least two different excitation wavelengths and a light-guiding device used to deliver polychromatic light at an output when excited by the radiation in a non-linear interaction regime.Type: ApplicationFiled: March 8, 2005Publication date: September 20, 2007Applicants: HORIBA ABX SAS, Universite De Limoges, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRSInventors: Philippe Nerin, Pierre-Alain Champert, Sebastien Fevrier, Philippe Roy, Vincent Couderc, Philippe Leproux, Ludovic Grossard
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Publication number: 20070189926Abstract: A device for supplying whole blood analyzers with tubes of blood. A stirring device is arranged upstream with respect to at least one analyzer. A first transport device conveys blood tubes one after another in front of the stirring device, and a second transport device conveys the blood tubes stirred by the stirring device one after another to a sampling point of the analyzer. A mechanism picks up separately the blood tubes which are not yet stirred, places the tubes in front of the stirring device to be stirred thereby, and to be separately removed from the stirring device and placed on a transport for conveying the stirred tubes to the sampling point of the analyzer, thereby making it possible to use at least one analyzed devoid of stirring.Type: ApplicationFiled: March 11, 2005Publication date: August 16, 2007Applicant: HORIBA ABX SASInventor: Roger Le Comte