Patents Assigned to Hutchison MediPharma Enterprises Limited
  • Pyrimidine derivatives
    Patent number: 8901143
    Abstract: A compound of the following formula: wherein R1, R2, R3, R4, R5, T, U, V, X, Y, Z, G, and Z are defined herein. It also discloses a method of treating an angiogenesis-related disorder, e.g., cancer or age-related macular degeneration, with such a compound.
    Type: Grant
    Filed: November 8, 2012
    Date of Patent: December 2, 2014
    Assignee: Hutchison MediPharma Enterprises Limited
    Inventors: Wei-Guo Su, Hong Jia, Weihan Zhang, Yumin Cui, Xiaoqiang Yan, Yongxin Ren, Jifeng Duan, Yang Sai
  • QUINAZOLINE DERIVATIVES
    Publication number: 20130217661
    Abstract: Quinazoline derivatives of the following formula: wherein R1, R2, R3, R4, R5, X, Y, and Z are defined herein. It also discloses a method of treating cancer with one of these compounds.
    Type: Application
    Filed: March 18, 2013
    Publication date: August 22, 2013
    Applicant: HUTCHISON MEDIPHARMA ENTERPRISES LIMITED
    Inventor: Hutchison Medipharma Enterprises Limited
  • Use of substituted quinazoline compounds in treating age-related macular degeneration
    Patent number: 8497372
    Abstract: Quinazoline derivatives of the following formula: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, and Z are defined herein. It also discloses a method of treating an angiogenesis-related disorder with one of these compounds.
    Type: Grant
    Filed: June 4, 2012
    Date of Patent: July 30, 2013
    Assignee: Hutchison Medipharma Enterprises Limited
    Inventors: Wei-Guo Su, Weihan Zhang, Xiaoqiang Yan, Yumin Cui, Yongxin Ren, Jifeng Duan
  • Quinazoline derivatives
    Patent number: 8426430
    Abstract: Quinazoline derivatives of the following formula: wherein R1, R2, R3, R4, R5, X, Y, and Z are defined herein. It also discloses a method of treating cancer with one of these compounds.
    Type: Grant
    Filed: June 30, 2008
    Date of Patent: April 23, 2013
    Assignee: Hutchison Medipharma Enterprises Limited
    Inventors: Weihan Zhang, Wei-Guo Su, Haibin Yang, Yumin Cui, Yongxin Ren, Xiaoqiang Yan
  • ANDROGRAPHIS PANICULATA EXTRACT
    Publication number: 20130023493
    Abstract: An extract of Andrographis paniculata extract containing andrographolide, 14-deoxyandrographolide, 14-deoxy-11,12-dehydroandrographolide, neoandrographolide, polysacchorides, and flavanoids. Also disclosed is a pharmaceutical composition containing such an extract and its use for treating inflammatory bowel disease.
    Type: Application
    Filed: September 11, 2012
    Publication date: January 24, 2013
    Applicant: HUTCHISON MEDIPHARMA ENTERPRISES LIMITED
    Inventors: Jifeng Duan, Zhiming Ma, Xiaoqiang Yan, Weihan Zhang, Tao Wang, Yu Cai
  • Pyrimidine derivatives
    Patent number: 8349859
    Abstract: A compound of the following formula: wherein R1, R2, R3, R4, R5, T, U, V, X, Y, Z, G, and Z are defined herein. It also discloses a method of treating an angiogenesis-related disorder, e.g., cancer or age-related macular degeneration, with such a compound.
    Type: Grant
    Filed: April 16, 2008
    Date of Patent: January 8, 2013
    Assignee: Hutchison Medipharma Enterprises Limited
    Inventors: Wei-Guo Su, Hong Jia, Weihan Zhang, Yumin Cui, Xiaoqiang Yan, Yongxin Ren, Jifeng Duan, Yang Sai
  • Use of substituted quinazoline compounds in treating angiogenesis-related diseases
    Patent number: 8212033
    Abstract: Quinazoline derivatives of the following formula: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, and Z are defined herein. It also discloses a method of treating an angiogenesis-related disorder with one of these compounds.
    Type: Grant
    Filed: September 29, 2010
    Date of Patent: July 3, 2012
    Assignee: Hutchison Medipharma Enterprises Limited
    Inventors: Wei-Guo Su, Weihan Zhang, Xiaoqiang Yan, Yumin Cui, Yongxin Ren, Jifeng Duan
  • ANDROGRAPHIS EXTRACT FORMULATIONS
    Publication number: 20110142944
    Abstract: A pharmaceutical formulation containing 50-90% by weight a powdered extract of Andrographis paniculata and 5-50% by weight a powdered blocking agent. The formulation may further contain a pore-forming agent, a filler, a lubricant, or a glidant. Also described are a method for preparing this pharmaceutical formulation and a method for treating inflammatory disease, immunological disease, or respiratory disease with it.
    Type: Application
    Filed: December 15, 2010
    Publication date: June 16, 2011
    Applicant: Hutchison Medipharma Enterprises Limited, Offshore Group Chambers
    Inventors: Yuqing Wang, Li Wang, Xun Zhang
  • Decahydronaphthalene compounds
    Patent number: 7902359
    Abstract: This invention relates to a compound of the following formula: wherein R1, R2, R3, G, and Z are defined herein. It also relates to is methods of treating autoimmune disease, cancer, and atherosclerosis with such a compound.
    Type: Grant
    Filed: December 11, 2007
    Date of Patent: March 8, 2011
    Assignee: Hutchison MediPharma Enterprises Limited
    Inventors: Tao Wang, Weihan Zhang, Xiaoqiang Yan, Weiguo Su, Jifeng Duan, Yu Cai
  • Cytokine inhibitors
    Patent number: 7868001
    Abstract: A compound of Formula I: Each variable is defined in the specification. This invention relates to a method of decreasing a level of a cytokine (e.g., TNF? or interlukine such as IL-1?) in a subject with a compound of Formula I. It also relates to a method of treating a disorder mediated by an overproduction of a cytokine with such a compound.
    Type: Grant
    Filed: November 2, 2007
    Date of Patent: January 11, 2011
    Assignee: Hutchison Medipharma Enterprises Limited
    Inventors: Wei Deng, Wei-Guo Su, Yu Cai, Jeff Duan
  • Substituted quinazoline compounds and their use in treating angiogenesis-related diseases
    Patent number: 7829574
    Abstract: Substituted quinazoline compounds of the following formula: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, and X are defined herein. It also discloses a pharmaceutical composition containing one of these compounds.
    Type: Grant
    Filed: May 9, 2008
    Date of Patent: November 9, 2010
    Assignee: Hutchison MediPharma Enterprises Limited
    Inventors: Wei-Guo Su, Weihan Zhang, Xiaoqiang Yan, Yumin Cui, Yongxin Ren, Jifeng Duan
  • Pyrimidine compounds
    Patent number: 7737157
    Abstract: Pyrimidine compounds of the following formula: wherein R1, R2, R3, R4, R5, X, Q1, Q2, and Q3 are defined herein. Also disclosed is a method of treating cancer with one of these compounds.
    Type: Grant
    Filed: August 29, 2008
    Date of Patent: June 15, 2010
    Assignee: Hutchison MediPharma Enterprises Limited
    Inventors: Wei-Guo Su, Hong Jia, Rick B. Ye, Yang Sai
  • PYRIMIDINE COMPOUNDS
    Publication number: 20100056512
    Abstract: Pyrimidine compounds of the following formula: wherein R1, R2, R3, R4, R5, X, Q1, Q2, and Q3 are defined herein. Also disclosed is a method of treating cancer with one of these compounds.
    Type: Application
    Filed: August 29, 2008
    Publication date: March 4, 2010
    Applicant: Hutchison MediPharma Enterprises Limited
    Inventors: Wei-Guo Su, Hong Jia, Rick B. Ye, Yang Sai
  • QUINAZOLINE DERIVATIVES
    Publication number: 20100009958
    Abstract: Quinazoline derivatives of the following formula: wherein R1, R2, R3, R4, R5, X, Y, and Z are defined herein. It also discloses a method of treating cancer with one of these compounds.
    Type: Application
    Filed: June 30, 2008
    Publication date: January 14, 2010
    Applicant: Hutchison MediPharma Enterprises Limited
    Inventors: Weihan Zhang, Wei-Guo Su, Haibin Yang, Yumin Cui, Yongxin Ren, Xiaoqiang Yan
  • Costunolide derivatives
    Patent number: 7622465
    Abstract: Disclosed are methods for inhibiting TNF? expression, IL-1? expression, iNOS expression, and NF-?B activity and methods for treating autoimmune disease, cancer, or atherosclerosis with a compound of the following formula:
    Type: Grant
    Filed: December 16, 2008
    Date of Patent: November 24, 2009
    Assignee: Hutchison Medipharma Enterprises Limited
    Inventors: Wei-Guo Su, Hong Jia, Xiaoqiang Yan, Jifeng Duan, Tao Wang, Yu Cai, Weihan Zhang
  • QUINAZOLINE DERIVATIVES
    Publication number: 20090281130
    Abstract: Quinazoline derivatives of the following formula: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, and Z are defined herein. It also discloses a method of treating an angiogenesis-related disorder with one of these compounds.
    Type: Application
    Filed: May 9, 2008
    Publication date: November 12, 2009
    Applicant: Hutchison Medipharma Enterprises Limited
    Inventors: Wei-Guo Su, Weihan Zhang, Xiaoqiang Yan, Yumin Cui, Yongxin Ren, Jifeng Duan
  • Costunolide Derivatives
    Publication number: 20090131427
    Abstract: Disclosed are methods for inhibiting TNF? expression, IL-1? expression, iNOS expression, and NF-?B activity and methods for treating autoimmune disease, cancer, or atherosclerosis with a compound of the following formula:
    Type: Application
    Filed: December 16, 2008
    Publication date: May 21, 2009
    Applicant: HUTCHISON MEDIPHARMA ENTERPRISES LIMITED
    Inventors: Weiguo Su, Hong Jia, Weihan Zhang, Xiaoqiang Yan, Jifeng Duan, Tao Wang, Yu Cai
  • ANDROGRAPHIS PANICULATA EXTRACT
    Publication number: 20090117210
    Abstract: An extract of Andrographis paniculata extract containing andrographolide, 14-deoxyandrographolide, 14-deoxy-11,12-dehydroandrographolide, neoandrographolide, polysacchorides, and flavanoids. Also disclosed is a pharmaceutical composition containing such an extract and its use for treating inflammatory bowel disease.
    Type: Application
    Filed: November 4, 2008
    Publication date: May 7, 2009
    Applicant: Hutchison MediPharma Enterprises Limited
    Inventors: Jifeng Duan, Zhiming Ma, Xiaoqiang Yan, Weihan Zhang, Tao Wang, Yu Cai
  • Crude extracts from andrographis paniculata
    Patent number: RE42718
    Abstract: This invention relates to a method of inhibiting TNF? or IL-1? expression with an extract of Andrographis paniculata. The extract contains andrographolide, 14-deoxy-andrographolide, 14-deoxy-11,12-dehydrogen-andrographolide, and neoandrographolide.
    Type: Grant
    Filed: March 4, 2010
    Date of Patent: September 20, 2011
    Assignee: Hutchison Medipharma Enterprises Limited
    Inventors: Xiaoqiang Yan, Tao Wang, Zhiming Ma, Weihan Zhang, Jifeng Duan, Yu Cai
  • Crude extracts from
    Patent number: RE43423
    Abstract: This invention relates to a method of inhibiting TNF? or IL-1? expression with an extract of Andrographis paniculata. The extract contains andrographolide, 14-deoxy-andrographolide, 14-deoxy-11,12-dehydrogen-andrographolide, and neoandrographolide.
    Type: Grant
    Filed: July 22, 2011
    Date of Patent: May 29, 2012
    Assignee: Hutchison MediPharma Enterprises Limited
    Inventors: Xiaoqiang Yan, Tao Wang, Zhiming Ma, Weihan Zhang, Jifeng Duan, Yu Cai