Patents Assigned to Hutchison MediPharma Enterprises Limited
  • CYTOKINE INHIBITORS
    Publication number: 20090118292
    Abstract: A compound of Formula I: Each variable is defined in the specification. This invention relates to a method of decreasing a level of a cytokine (e.g., TNF? or interlukine such as IL-1?) in a subject with a compound of Formula I. It also relates to a method of treating a disorder mediated by an overproduction of a cytokine with such a compound.
    Type: Application
    Filed: November 2, 2007
    Publication date: May 7, 2009
    Applicant: Hutchison Medipharma Enterprises Limited
    Inventors: Wei Deng, Wei-Guo Su, Yu Cai, Jeff Duan
  • ANDROGRAPHIS PANICULATA EXTRACT
    Publication number: 20090117209
    Abstract: An extract of Andrographis paniculata extract containing andrographolide, 14-deoxyandrographolide, 14-deoxy-11,12-dehydroandrographolide, neoandrographolide, polysacchlorides, and flavanoids. Also disclosed is a pharmaceutical composition containing such an extract and its use for treating inflammatory bowel disease.
    Type: Application
    Filed: November 2, 2007
    Publication date: May 7, 2009
    Applicant: Hutchison Medipharma Enterprises Limited
    Inventors: Jifeng Duan, Zhiming Ma, Xiaoqiang Yan, Weihan Zhang, Tao Wang, Yu Cai
  • Costunolide derivatives
    Patent number: 7488836
    Abstract: A compound of the following formula: wherein X, Y, and Z are as defined herein. Also disclosed are methods for inhibiting TNF? expression, IL-1? expression, iNOS expression, and NF-?B activity and methods for treating autoimmune disease, cancer, or atherosclerosis with such a compound.
    Type: Grant
    Filed: August 14, 2007
    Date of Patent: February 10, 2009
    Assignee: Hutchison Medipharma Enterprises Limited
    Inventors: Weiguo Su, Hong Jia, Weihan Zhang, Xiaoqiang Yan, Jifeng Duan, Tao Wang, Yu Cai
  • Crude extracts from
    Patent number: 7341748
    Abstract: This invention relates to a method of inhibiting TNF? or IL-1? expression with an extract of Andrographis paniculata. The extract contains andrographolide, 14-deoxy-andrographolide, 14-deoxy-11,12-dehydrogen-andrographolide, and neoandrographolide.
    Type: Grant
    Filed: April 27, 2005
    Date of Patent: March 11, 2008
    Assignee: Hutchison MediPharma Enterprises Limited
    Inventors: Xiaoqiang Yan, Tao Wang, Zhiming Ma, Weihan Zhang, Jifeng Duan, Yu Cai
  • DIHYDROBENZOQUINONE COMPOUNDS
    Publication number: 20070286906
    Abstract: Dihydrobenzoquinone compounds of the following formula: wherein R1, R2, R3, and R4 are defined herein. Also disclosed is a method of treating cancer with one of the dihydrobenzoquinone compounds.
    Type: Application
    Filed: April 27, 2007
    Publication date: December 13, 2007
    Applicant: Hutchison MediPharma Enterprises Limited
    Inventors: Weihan Zhang, Weiguo Su, Yumin Cui, Yongxin Ren, Xiaoqiang Yan, Jifeng Duan