Abstract: Compound of Formula A and pharmaceutically acceptable salts thereof and crystalline Forms I and II of Compound of Formula A! Also, methods for the preparation of such compounds, pharmaceutical compositions comprising such compounds, and methods for their uses.
Type:
Grant
Filed:
December 12, 2013
Date of Patent:
February 3, 2015
Assignee:
Hutchison Medipharma Limited
Inventors:
Wei-Guo Su, Weihan Zhang, Hong Jia, Yumin Cui, Yongxin Ren, Yang Sai, Zhenping Wu, Wenji Li, Jiangyong Shao, Zhenping Tian
Abstract: A compound of the following formula: wherein R1, R2, R3, R4, R5, T, U, V, X, Y, Z, G, and Z are defined herein. It also discloses a method of treating an angiogenesis-related disorder, e.g., cancer or age-related macular degeneration, with such a compound.
Abstract: Compound of Formula A and pharmaceutically acceptable salts thereof and crystalline Forms I and II of Compound of Formula A! Also, methods for the preparation of such compounds, pharmaceutical compositions comprising such compounds, and methods for their uses.
Type:
Application
Filed:
December 12, 2013
Publication date:
July 17, 2014
Applicant:
HUTCHISON MEDIPHARMA LIMITED
Inventors:
WEI-GUO SU, WEIHAN ZHANG, HONG JIA, YUMIN CUI, YONGXIN REN, YANG SAI, ZHENPING WU, WENJI LI, JIANGYONG SHAO, ZHENPING TIAN
Abstract: Provided are pyridopyrazine compounds of formula (1), pharmaceutical compositions thereof and methods of use therefore, wherein R1, R2, R3, R4 and m are as defined in the specification.
Abstract: Compound of Formula A and pharmaceutically acceptable salts thereof and crystalline Forms I and II of Compound of Formula A! Also, methods for the preparation of such compounds, pharmaceutical compositions comprising such compounds, and methods for their uses.
Type:
Grant
Filed:
November 23, 2010
Date of Patent:
February 25, 2014
Assignee:
Hutchison MediPharma Limited
Inventors:
Wei-Guo Su, Weihan Zhang, Hong Jia, Yumin Cui, Yongxin Ren, Yang Sai, Zhenping Wu, Wenji Li, Jiangyong Shao, Zhenping Tian
Abstract: Quinazoline derivatives of the following formula: wherein R1, R2, R3, R4, R5, X, Y, and Z are defined herein. It also discloses a method of treating cancer with one of these compounds.
Abstract: Provided are certain triazolopyridines and triazolopyrazines of Formula 1. wherein X, Y, R1, R2, R3, R4 and R5 have any of the meanings described herein; processes for their preparation, pharmaceutical compositions containing them, and their use in the treatment of cell proliferative disorders.
Abstract: The present invention provides pyrimidinyl indole compounds as novel kinase inhibitors for the treatment of cancer and inflammatory diseases.
Abstract: Quinazoline derivatives of the following formula: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, and Z are defined herein. It also discloses a method of treating an angiogenesis-related disorder with one of these compounds.
Abstract: Provided are certain quinazoline compounds, compositions thereof and methods of use thereof. These quinazoline compounds can effectively inhibit the overexpression and/or overactivity of epidermal growth factor receptor (EGFR).
Type:
Application
Filed:
May 25, 2011
Publication date:
July 4, 2013
Applicant:
Hutchison Medipharma Limited
Inventors:
Weihan Zhang, Wei-Guo Su, Haibin Yang, Yumin Cui, Yongxin Ren, Xiaoqiang Yan
Abstract: An apparatus for integrating sensors with a traffic signal. A camera is operably disposed within a housing. The housing is attached to an object such that the camera can observe traffic flowing past a traffic signal. A visor is attached to the housing such that an optical aperture of the camera is covered by the visor, wherein the visor comprises a roof having an angle that slopes, relative to the housing, towards the optical aperture, wherein the visor further comprises a floor connected to the roof, and wherein the floor extends outwardly from the housing.
Abstract: Quinazoline derivatives of the following formula: wherein R1, R2, R3, R4, R5, X, Y, and Z are defined herein. It also discloses a method of treating cancer with one of these compounds.
Abstract: The present invention provides pyrimidinyl indole compounds as novel kinase inhibitors for the treatment of cancer and inflammatory diseases.
Abstract: An extract of Andrographis paniculata extract containing andrographolide, 14-deoxyandrographolide, 14-deoxy-11,12-dehydroandrographolide, neoandrographolide, polysacchorides, and flavanoids. Also disclosed is a pharmaceutical composition containing such an extract and its use for treating inflammatory bowel disease.
Abstract: A compound of the following formula: wherein R1, R2, R3, R4, R5, T, U, V, X, Y, Z, G, and Z are defined herein. It also discloses a method of treating an angiogenesis-related disorder, e.g., cancer or age-related macular degeneration, with such a compound.
Abstract: Provided are devices, methods, communication managers and user interface solutions that enable access to multiple services from a mobile communications device. A mobile communication device that provides telephony services via a PSTN also includes multiple communication channels that exploit packet data transfer via an IP network, for example enabling VoIP, instant messaging and other internet-based communication services to be initiated from a mobile telephone.
Type:
Grant
Filed:
October 13, 2008
Date of Patent:
September 25, 2012
Assignee:
Hutchison Whampoa Three G IP (Bahamas) Limited
Inventors:
Christopher Henry Seal, Gaetano Vitolo, Kevin David Joyce, Nadir El Yakhlifi
Abstract: Quinazoline derivatives of the following formula: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, and Z are defined herein. It also discloses a method of treating an angiogenesis-related disorder with one of these compounds.
Abstract: This invention relates to a method of inhibiting TNF? or IL-1? expression with an extract of Andrographis paniculata. The extract contains andrographolide, 14-deoxy-andrographolide, 14-deoxy-11,12-dehydrogen-andrographolide, and neoandrographolide.
Abstract: This invention relates to a method of inhibiting TNF? or IL-1? expression with an extract of Andrographis paniculata. The extract contains andrographolide, 14-deoxy-andrographolide, 14-deoxy-11,12-dehydrogen-andrographolide, and neoandrographolide.