Patents Assigned to Hyperfine Operations, Inc.
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Publication number: 20260140210Abstract: Systems and methods for operating a magnetic resonance imaging (MRI) system are provided. The MRI system includes a magnetics system and a power system configured to provide power to at least some of the magnetics system. The power system includes an energy storage device and a power supply configured to receive mains electricity. The MRI system also includes at least one controller configured to control the MRI system to operate in accordance with a pulse sequence at least in part by generating, by using power supplied by the power supply and supplemental power supplied by the energy storage device, at least one gradient field using at least one gradient coil of the magnetics system.Type: ApplicationFiled: June 20, 2025Publication date: May 21, 2026Applicant: Hyperfine Operations, Inc.Inventor: Michael Twieg
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Publication number: 20260083343Abstract: According to some aspects, a magnetic resonance imaging system capable of imaging a patient is provided. The magnetic resonance imaging system comprising at least one B0 magnet to produce a magnetic field to contribute to a B0 magnetic field for the magnetic resonance imaging system and a member configured to engage with a releasable securing mechanism of a radio frequency coil apparatus, the member attached to the magnetic resonance imaging system at a location so that, when the member is engaged with the releasable securing mechanism of the radio frequency coil apparatus, the radio frequency coil apparatus is secured to the magnetic resonance imaging system substantially within an imaging region of the magnetic resonance imaging system.Type: ApplicationFiled: May 16, 2025Publication date: March 26, 2026Applicant: Hyperfine Operations, Inc.Inventors: Anne Michele Nelson, Christopher Thomas McNulty, Jeremy Christopher Jordan, Michael Stephen Poole, Gang Chen
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Publication number: 20260051100Abstract: Systems and methods for training a machine-learning model to generate denoised and dealiased image data are provided. The present disclosure provides techniques for training a machine-learning (ML) model to generate denoised and dealiased imaging data. A method includes (1) training a first ML model using a first training dataset comprising first image data to obtain a second ML model; and (2) training (a) the second ML model or (b) a third ML model using a second training dataset to obtain a fourth ML model. The second training dataset includes (i) the first image data and (ii) training image data obtained by applying at least one of the second ML model or the third ML model to second image data. The denoising and dealiasing ML model may be either the fourth ML model or derived from the fourth ML model.Type: ApplicationFiled: October 27, 2025Publication date: February 19, 2026Applicant: Hyperfine Operations, Inc.Inventor: Jo Schlemper
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Patent number: 12553968Abstract: An apparatus for providing a B0 magnetic field for a magnetic resonance imaging system. The apparatus includes at least one permanent B0 magnet to contribute a magnetic field to the B0 magnetic field for the MRI system and a ferromagnetic frame configured to capture and direct at least some of the magnetic field generated by the B0 magnet. The ferromagnetic frame includes a first post having a first end and a second end, a first multi-pronged member coupled to the first end, and a second multi-pronged member coupled to the second end, wherein the first and second multi-pronged members support the at least one permanent B0 magnet.Type: GrantFiled: April 29, 2024Date of Patent: February 17, 2026Assignee: Hyperfine Operations, Inc.Inventors: Cedric Hugon, Hadrien A. Dyvorne, Michael Stephen Poole
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Patent number: 12514463Abstract: A magnetic resonance (MR) imaging system, comprising a magnetics system having a plurality of magnetics components configured to produce magnetic fields for performing magnetic resonance imaging, and a sensor configured to detect electromagnetic interference conducted by a patient into an imaging region of the MR imaging system. The sensor may comprise at least one electrical conductor configured for electrically coupling to the patient. The MR imaging system may further comprise a noise reduction system configured to receive the electromagnetic interference from the sensor and to suppress electromagnetic interference in detected MR signals received by the MR imaging system based on the electromagnetic interference detected by the sensor.Type: GrantFiled: May 20, 2024Date of Patent: January 6, 2026Assignee: Hyperfine Operations, Inc.Inventors: Hadrien A. Dyvorne, Laura Sacolick, Carole Lazarus, Eddy B. Boskamp, Jeremy Christopher Jordan
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Patent number: 12504487Abstract: An apparatus for providing a B0 magnetic field for a magnetic resonance imaging system. The apparatus includes at least one first B0 magnet configured to produce a first magnetic field to contribute to the B0 magnetic field for the magnetic resonance imaging system, the at least one first B0 magnet comprising a first plurality of permanent magnet rings including at least two rings with respective different heights.Type: GrantFiled: June 28, 2023Date of Patent: December 23, 2025Assignee: Hyperfine Operations, Inc.Inventors: Michael Stephen Poole, Cedric Hugon, Christopher Thomas McNulty
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Patent number: 12461177Abstract: A radio frequency apparatus is described herein for facilitating imaging of a patient positioned within a magnetic resonance imaging system comprising a B0 magnet. The radio frequency apparatus may be configured to detect magnetic resonance signals emitted from anatomy of a patient when positioned within a low-field magnetic resonance imaging system, the radio frequency apparatus comprising a flexible substrate capable of being positioned about the anatomy of the patient and a plurality of radio frequency coils coupled to the flexible substrate, each of the plurality of radio frequency coils forming a plurality of turns.Type: GrantFiled: July 14, 2023Date of Patent: November 4, 2025Assignee: Hyperfine Operations, Inc.Inventors: Gang Chen, Anne Michele Nelson
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Patent number: 12446832Abstract: Aspects relate to providing radio frequency components responsive to magnetic resonance signals. According to some aspects, a radio frequency component comprises at least one coil having a conductor arranged in a plurality of turns oriented about a region of interest to respond to corresponding magnetic resonant signal components. According to some aspects, the radio frequency component comprises a plurality of coils oriented to respond to corresponding magnetic resonant signal components. According to some aspects, an optimization is used to determine a configuration for at least one radio frequency coil.Type: GrantFiled: June 14, 2023Date of Patent: October 21, 2025Assignee: Hyperfine Operations, Inc.Inventors: Michael Stephen Poole, Gregory L. Charvat, Todd Rearick, Jonathan M. Rothberg
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Publication number: 20250321304Abstract: A radio frequency (RF) coil apparatus is described herein for facilitating imaging of a patient positioned within a magnetic resonance imaging (MRI) system, the MRI system comprising a B0 magnet. The apparatus may comprise a frame comprising a first plate and a second plate disposed opposite the first plate; and an RF transmit coil comprising a plurality of conductors connected in series, the plurality of conductors being would around the frame and forming a plurality of turns. According to some aspects, there is provided an MRI system configured to image a patient positioned within the MRI system, the MRI system comprises a B0 magnet that produces a B0 magnetic field and the RF coil apparatus.Type: ApplicationFiled: June 24, 2025Publication date: October 16, 2025Applicant: Hyperfine Operations, Inc.Inventors: Eddy B. Boskamp, Michael Stephen Poole
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Patent number: 12442880Abstract: Techniques are described for controlling components of a Magnetic Resonance Imaging (MRI) system with a single controller, such as a Field Programmable Gate Array (FPGA), by dynamically instructing the controller to issue commands to the components using a processor coupled to the controller. According to some aspects, the controller may issue commands to the components of the MRI system whilst actively receiving commands from the processor to be later issued to the components.Type: GrantFiled: July 3, 2023Date of Patent: October 14, 2025Assignee: Hyperfine Operations, Inc.Inventors: Laura Sacolick, Jonathan Lowthert, Jeremy Christopher Jordan, Hadrien A. Dyvorne
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Patent number: 12436212Abstract: Methods and apparatus for reducing noise in RF signal chain circuitry for a low-field magnetic resonance imaging system are provided. A switching circuit in the RF signal chain circuitry may include at least one field effect transistor (FET) configured to operate as an RF switch at an operating frequency of less than 10 MHz. A decoupling circuit may include tuning circuitry coupled across inputs of an amplifier and active feedback circuitry coupled between an output of the amplifier and an input of the amplifier, wherein the active feedback circuitry includes a feedback capacitor configured to reduce a quality factor of an RF coil coupled to the amplifier.Type: GrantFiled: April 24, 2023Date of Patent: October 7, 2025Assignee: Hyperfine Operations, Inc.Inventors: Hadrien A. Dyvorne, Todd Rearick
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Publication number: 20250306150Abstract: A magnetic resonance imaging (MRI) system, comprising: a magnetics system comprising: a B0 magnet configured to provide a B0 field for the MRI system; gradient coils configured to provide gradient fields for the MRI system; and at least one RF coil configured to detect magnetic resonance (MR) signals; and a controller configured to: control the magnetics system to acquire MR spatial frequency data using non-Cartesian sampling; and generate an MR image from the acquired MR spatial frequency data using a neural network model comprising one or more neural network blocks including a first neural network block, wherein the first neural network block is configured to perform data consistency processing using a non-uniform Fourier transformation.Type: ApplicationFiled: November 14, 2024Publication date: October 2, 2025Applicant: Hyperfine Operations, Inc.Inventors: Jo Schlemper, Seyed Sadegh Mohseni Salehi, Michal Sofka, Prantik Kundu, Ziyi Wang, Carole Lazarus, Hadrien A. Dyvorne, Laura Sacolick, Rafael O'Halloran, Jonathan M. Rothberg
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Publication number: 20250298108Abstract: A method of producing a permanent magnet shim configured to improve a profile of a B0 magnetic field produced by a B0 magnet is provided. The method comprises determining deviation of the B0 magnetic field from a desired B0 magnetic field, determining a magnetic pattern that, when applied to magnetic material, produces a corrective magnetic field that corrects for at least some of the determined deviation, and applying the magnetic pattern to the magnetic material to produce the permanent magnet shim. According to some aspects, a permanent magnet shim for improving a profile of a B0 magnetic field produced by a B0 magnet is provided. The permanent magnet shim comprises magnetic material having a predetermined magnetic pattern applied thereto that produces a corrective magnetic field to improve the profile of the B0 magnetic field.Type: ApplicationFiled: November 4, 2024Publication date: September 25, 2025Applicant: Hyperfine Operations, Inc.Inventors: Cedric Hugon, Michael Stephen Poole, Tyler S. Ralston
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Publication number: 20250283964Abstract: In some aspects, a method of operating a magnetic resonance imaging system comprising a B0 magnet and at least one thermal management component configured to transfer heat away from the B0 magnet during operation is provided. The method comprises providing operating power to the B0 magnet, monitoring a temperature of the B0 magnet to determine a current temperature of the B0 magnet, and operating the at least one thermal management component at less than operational capacity in response to an occurrence of at least one event.Type: ApplicationFiled: October 24, 2024Publication date: September 11, 2025Applicant: Hyperfine Operations, Inc.Inventors: Jonathan M. Rothberg, Jeremy Christopher Jordan, Michael Stephen Poole, Laura Sacolick, Todd Rearick, Gregory L. Charvat
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Publication number: 20250264564Abstract: Techniques of prospectively compensating for motion of a subject being imaged by an MRI system, the MRI system comprising a plurality of magnetics components including at least one gradient coil and at least one radio-frequency (RF) coil, the techniques comprising: obtaining first spatial frequency data and second spatial frequency data by operating the MRI system in accordance with a pulse sequence, wherein the pulse sequence is associated with a sampling path that includes at least two non-contiguous portions each for sampling a central region of k-space; determining a transformation using a first image obtained using the first spatial frequency data and a second image obtained using the second spatial frequency data; correcting the pulse sequence using the determined transformation to obtain a corrected pulse sequence; and obtaining additional spatial frequency data in accordance with the corrected pulse sequence.Type: ApplicationFiled: October 1, 2024Publication date: August 21, 2025Applicant: Hyperfine Operations, Inc.Inventors: Carole Lazarus, Rafael O'Halloran, Hadrien A. Dyvorne
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Publication number: 20250264563Abstract: Techniques for generating magnetic resonance (MR) images of a subject from MR data obtained by a magnetic resonance imaging (MRI) system, the techniques including: obtaining input MR data obtained by imaging the subject using the MRI system; generating a plurality of transformed input MR data instances by applying a respective first plurality of transformations to the input MR data; generating a plurality of MR images from the plurality of transformed input MR data instances and the input MR data using a non-linear MR image reconstruction technique; generating an ensembled MR image from the plurality of MR images at least in part by: applying a second plurality of transformations to the plurality of MR images to obtain a plurality of transformed MR images; and combining the plurality of transformed MR images to obtain the ensembled MR image; and outputting the ensembled MR image.Type: ApplicationFiled: September 30, 2024Publication date: August 21, 2025Applicant: Hyperfine Operations, Inc.Inventors: Jo Schlemper, Seyed Sadegh Mohseni Salehi, Michal Sofka
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Patent number: 12366622Abstract: A radio frequency (RF) coil apparatus is described herein for facilitating imaging of a patient positioned within a magnetic resonance imaging (MRI) system, the MRI system comprising a B0 magnet. The apparatus may comprise a frame comprising a first plate and a second plate disposed opposite the first plate; and an RF transmit coil comprising a plurality of conductors connected in series, the plurality of conductors being would around the frame and forming a plurality of turns. According to some aspects, there is provided an MRI system configured to image a patient positioned within the MRI system, the MRI system comprises a B0 magnet that produces a B0 magnetic field and the RF coil apparatus.Type: GrantFiled: July 14, 2023Date of Patent: July 22, 2025Assignee: Hyperfine Operations, Inc.Inventors: Eddy B. Boskamp, Michael Stephen Poole
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Patent number: 12352834Abstract: Systems and methods for operating a magnetic resonance imaging (MRI) system are provided. The MRI system includes a magnetics system and a power system configured to provide power to at least some of the magnetics system. The power system includes an energy storage device and a power supply configured to receive mains electricity. The MRI system also includes at least one controller configured to control the MRI system to operate in accordance with a pulse sequence at least in part by generating, by using power supplied by the power supply and supplemental power supplied by the energy storage device, at least one gradient field using at least one gradient coil of the magnetics system.Type: GrantFiled: December 21, 2023Date of Patent: July 8, 2025Assignee: Hyperfine Operations, Inc.Inventor: Michael Twieg
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Patent number: 12324656Abstract: According to some aspects, a magnetic resonance imaging system capable of imaging a patient is provided. The magnetic resonance imaging system comprising at least one B0 magnet to produce a magnetic field to contribute to a B0 magnetic field for the magnetic resonance imaging system and a member configured to engage with a releasable securing mechanism of a radio frequency coil apparatus, the member attached to the magnetic resonance imaging system at a location so that, when the member is engaged with the releasable securing mechanism of the radio frequency coil apparatus, the radio frequency coil apparatus is secured to the magnetic resonance imaging system substantially within an imaging region of the magnetic resonance imaging system.Type: GrantFiled: March 20, 2023Date of Patent: June 10, 2025Assignee: Hyperfine Operations, Inc.Inventors: Anne Michele Nelson, Christopher Thomas McNulty, Jeremy Christopher Jordan, Michael Stephen Poole, Gang Chen
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Publication number: 20250182306Abstract: Some implementations relate to methods, systems, and computer-readable media for medical imaging. A method includes providing as input to the neural network, a first image and a second image, wherein the first image and the second image are reconstructed from a fast spin echo (FSE) magnetic resonance (MR) imaging sequence, determining, using the neural network, a dense displacement field based at least on the first image and the second image, obtaining, using the neural network, a transformed image based on the first image and the dense displacement field, wherein the transformed image is aligned with the second image, computing a registration loss value based on comparison of the transformed image and the second image, and adjusting one or more parameters of the neural network based on the registration loss value.Type: ApplicationFiled: March 20, 2024Publication date: June 5, 2025Applicant: Hyperfine Operations, Inc.Inventors: Neel Dey, Jo Schlemper, Seyed Sadegh Mohseni Salehi, Li Yao, Michal Sofka