Patents Assigned to Hyperfine Operations, Inc.
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Publication number: 20250148601Abstract: Systems and methods for simulating structures and images are disclosed. The techniques described herein can include obtaining a first image of a subject. The techniques can include determining a location for simulating a structure within the first image. The techniques can include simulating, according to the location, a shape for the structure. The techniques can include generating a mask according to the location and the shape for the structure. The techniques can include applying the mask to the first image to generate a second image simulating the structure.Type: ApplicationFiled: January 10, 2025Publication date: May 8, 2025Applicant: Hyperfine Operations, Inc.Inventors: Michal Sofka, Jo Schlemper
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Publication number: 20250139788Abstract: Systems and methods for training and deploying machine learning segmentation models to produce foreground masks of images are provided. The model may be used to generate foreground masks. A first method includes receiving images and annotations indicative of which pixels are in the foregrounds of the images, and generating, based on the images and the annotations, a model configured to receive, as input, a subject image and provide, as output, one or more probability maps indicative of foreground probabilities for pixels in the subject image. A foreground probability is indicative of a likelihood that the pixel is part of a foreground object or artifact in the image. Another method includes receiving a subject image, and generating a foreground mask for the subject image at least in part by applying a machine learning model to the subject image, the model having been generated based on disclosed training methods.Type: ApplicationFiled: January 3, 2025Publication date: May 1, 2025Applicant: Hyperfine Operations, Inc.Inventors: David Edmunds, Jo Schlemper, Michal Sofka
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Publication number: 20250127416Abstract: A magnetic resonance (MR) imaging system, comprising a magnetics system having a plurality of magnetics components configured to produce magnetic fields for performing magnetic resonance imaging, and a sensor configured to detect electromagnetic interference conducted by a patient into an imaging region of the MR imaging system. The sensor may comprise at least one electrical conductor configured for electrically coupling to the patient. The MR imaging system may further comprise a noise reduction system configured to receive the electromagnetic interference from the sensor and to suppress electromagnetic interference in detected MR signals received by the MR imaging system based on the electromagnetic interference detected by the sensor.Type: ApplicationFiled: May 20, 2024Publication date: April 24, 2025Applicant: Hyperfine Operations, Inc.Inventors: Hadrien A. Dyvorne, Laura Sacolick, Carole Lazarus, Eddy B. Boskamp, Jeremy Christopher Jordan
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Publication number: 20250110196Abstract: Systems and methods for suppressing electromagnetic interference (EMI) in magnetic resonance (MR) data are provided. The systems and methods include identifying a first subset of the MR data that is affected by EMI and suppressing EMI in the first subset to obtain a second subset of the MR data. Suppressing EMI in the first subset is performed by: applying a filter to the first subset of the MR data in order to suppress contribution of MR spin echo signals in the first subset of the MR data thereby obtaining signal-suppressed MR data; suppressing EMI in the signal-suppressed MR data to obtain EMI-suppressed MR data; and applying an inverse of the filter to the EMI-suppressed MR data to obtain the second subset of the MR data. The systems and methods include generating an MR image using the second subset of the MR data and outputting the generated MR image.Type: ApplicationFiled: December 12, 2024Publication date: April 3, 2025Applicant: Hyperfine Operations, Inc.Inventors: Deepansh Srivastava, Dingtian Zhang
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Publication number: 20250102603Abstract: An apparatus for providing a B0 magnetic field for a magnetic resonance imaging system. The apparatus includes at least one permanent B0 magnet to contribute a magnetic field to the B0 magnetic field for the MRI system and a ferromagnetic frame configured to capture and direct at least some of the magnetic field generated by the B0 magnet. The ferromagnetic frame includes a first post having a first end and a second end, a first multi-pronged member coupled to the first end, and a second multi-pronged member coupled to the second end, wherein the first and second multi-pronged members support the at least one permanent B0 magnet.Type: ApplicationFiled: April 29, 2024Publication date: March 27, 2025Applicant: Hyperfine Operations, Inc.Inventors: Cedric Hugon, Hadrien A. Dyvorne, Michael Stephen Poole
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Patent number: 12228629Abstract: Techniques for denoising a magnetic resonance (MR) image are provided, including: obtaining a noisy MR image; denoising the noisy MR image of the subject using a denoising neural network model, and outputting a denoised MR image. The denoising neural network model is trained by: generating first training data for training a first neural network model to denoise MR images by generating a first plurality of noisy MR images using clean MR data associated with a source domain and first MR noise data associated with the target domain; training the first neural network model using the first training data; generating training data for training the denoising neural network model by applying the first neural network model to a second plurality of noisy MR images and generating a plurality of denoised MR images; and training the denoising neural network model using the training data for training the denoising neural network model.Type: GrantFiled: October 7, 2021Date of Patent: February 18, 2025Assignee: Hyperfine Operations, Inc.Inventors: Neel Dey, Jo Schlemper, Seyed Sadegh Moshen Salehi, Michal Sofka, Prantik Kundu
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Patent number: 12189014Abstract: Techniques for compensating for presence of eddy currents during the operation of a magnetic resonance imaging (MRI) system in accordance with a pulse sequence, the pulse sequence comprising a gradient waveform associated with a target gradient field. The techniques include: compensating for presence of eddy currents during operation of the MRI system at least in part by correcting the gradient waveform using a nonlinear function of a characteristic of the gradient waveform to obtain a corrected gradient waveform; and operating the MRI system in accordance with the corrected gradient waveform to generate the target gradient field.Type: GrantFiled: May 22, 2023Date of Patent: January 7, 2025Assignee: Hyperfine Operations, Inc.Inventors: Hadrien A. Dyvorne, Cedric Hugon, Rafael O'Halloran, Laura Sacolick
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Patent number: 12181553Abstract: A magnetic resonance imaging (MRI) system, comprising: a magnetics system comprising: a B0 magnet configured to provide a B0 field for the MRI system; gradient coils configured to provide gradient fields for the MRI system; and at least one RF coil configured to detect magnetic resonance (MR) signals; and a controller configured to: control the magnetics system to acquire MR spatial frequency data using non-Cartesian sampling; and generate an MR image from the acquired MR spatial frequency data using a neural network model comprising one or more neural network blocks including a first neural network block, wherein the first neural network block is configured to perform data consistency processing using a non-uniform Fourier transformation.Type: GrantFiled: March 23, 2022Date of Patent: December 31, 2024Assignee: Hyperfine Operations, Inc.Inventors: Jo Schlemper, Seyed Sadegh Mohseni Salehi, Michal Sofka, Prantik Kundu, Ziyi Wang, Carole Lazarus, Hadrien A. Dyvorne, Laura Sacolick, Rafael O'Halloran, Jonathan M. Rothberg
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Patent number: 12169230Abstract: A method of producing a permanent magnet shim configured to improve a profile of a B0 magnetic field produced by a B0 magnet is provided. The method comprises determining deviation of the B0 magnetic field from a desired B0 magnetic field, determining a magnetic pattern that, when applied to magnetic material, produces a corrective magnetic field that corrects for at least some of the determined deviation, and applying the magnetic pattern to the magnetic material to produce the permanent magnet shim. According to some aspects, a permanent magnet shim for improving a profile of a B0 magnetic field produced by a B0 magnet is provided. The permanent magnet shim comprises magnetic material having a predetermined magnetic pattern applied thereto that produces a corrective magnetic field to improve the profile of the B0 magnetic field.Type: GrantFiled: July 11, 2023Date of Patent: December 17, 2024Assignee: Hyperfine Operations, Inc.Inventors: Cedric Hugon, Michael Stephen Poole, Tyler S. Ralston
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Patent number: 12153113Abstract: In some aspects, a method of operating a magnetic resonance imaging system comprising a B0 magnet and at least one thermal management component configured to transfer heat away from the B0 magnet during operation is provided. The method comprises providing operating power to the B0 magnet, monitoring a temperature of the B0 magnet to determine a current temperature of the B0 magnet, and operating the at least one thermal management component at less than operational capacity in response to an occurrence of at least one event.Type: GrantFiled: September 18, 2019Date of Patent: November 26, 2024Assignee: Hyperfine Operations, Inc.Inventors: Jonathan M. Rothberg, Jeremy Christopher Jordan, Michael Stephen Poole, Laura Sacolick, Todd Rearick, Gregory L. Charvat
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Publication number: 20240361405Abstract: Some aspects of the technology described herein provide for a deployable guard device configured to be coupled to a portable magnetic resonance imaging (MRI) device, the deployable guard device comprising: a plurality of arms that, when the deployable guard device is in a deployed position, at least partially surround a region within which a magnetic field strength of a magnetic field generated by the portable MRI device equals or exceeds a threshold field strength; and at least one deployment device configured to generate a force to facilitate moving the deployable guard device from an undeployed position to the deployed position.Type: ApplicationFiled: July 10, 2024Publication date: October 31, 2024Applicant: Hyperfine Operations, Inc.Inventors: Richard Q. Wang, Jonathan C. Schultz, Christopher Thomas McNulty, Ethan Liu, Yin Shing Chong, Timothy Bernhardt
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Patent number: 12130345Abstract: The present disclosure provides techniques for using opto-isolator circuitry to control switching circuitry configured to be coupled to a radio-frequency (RF) coil of a magnetic resonance imaging (MRI) system. In some embodiments, opto-isolator circuitry described herein may be configured to galvanically isolate switch controllers of the MRI system from the switching circuitry and/or provide feedback across an isolation barrier. Some embodiments provide an apparatus including switching circuitry configured to be coupled to an RF coil of an MRI system and a drive circuit that includes opto-isolator circuitry configured to control the switching circuitry. Some embodiments provide an MRI system that includes an RF coil configured to, when operated, transmit and/or receive RF signals to and/or from a field of view of the MRI system, switching circuitry coupled to the RF coil, and a drive circuit that includes opto-isolator circuitry configured to control the switching circuitry.Type: GrantFiled: September 13, 2023Date of Patent: October 29, 2024Assignee: Hyperfine Operations, Inc.Inventor: Michael Twieg
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Publication number: 20240345192Abstract: There is provided a radio frequency (RF) coil apparatus for facilitating magnetic resonance imaging (MRI) of at least a part of a patient's body that is positioned within an imaging region of an MRI system. The RF coil apparatus comprises at least one primary RF coil configured to emit RF pulses and generate a first magnetic field during operation of the MRI system and at least one secondary RF coil configured to generate a second magnetic field that, during operation of the MRI system, at least partially counteracts the first magnetic field in an external region outside of the imaging region of the MRI system.Type: ApplicationFiled: March 26, 2024Publication date: October 17, 2024Applicant: Hyperfine Operations, Inc.Inventor: Eddy B. Boskamp
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Patent number: 12105175Abstract: Techniques of prospectively compensating for motion of a subject being imaged by an MRI system, the MRI system comprising a plurality of magnetics components including at least one gradient coil and at least one radio-frequency (RF) coil, the techniques comprising: obtaining first spatial frequency data and second spatial frequency data by operating the MRI system in accordance with a pulse sequence, wherein the pulse sequence is associated with a sampling path that includes at least two non-contiguous portions each for sampling a central region of k-space; determining a transformation using a first image obtained using the first spatial frequency data and a second image obtained using the second spatial frequency data; correcting the pulse sequence using the determined transformation to obtain a corrected pulse sequence; and obtaining additional spatial frequency data in accordance with the corrected pulse sequence.Type: GrantFiled: June 12, 2023Date of Patent: October 1, 2024Assignee: Hyperfine Operations, Inc.Inventors: Carole Lazarus, Rafael O'Halloran, Hadrien A. Dyvorne
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Patent number: 12105173Abstract: Techniques for generating magnetic resonance (MR) images of a subject from MR data obtained by a magnetic resonance imaging (MRI) system, the techniques including: obtaining input MR data obtained by imaging the subject using the MRI system; generating a plurality of transformed input MR data instances by applying a respective first plurality of transformations to the input MR data; generating a plurality of MR images from the plurality of transformed input MR data instances and the input MR data using a non-linear MR image reconstruction technique; generating an ensembled MR image from the plurality of MR images at least in part by: applying a second plurality of transformations to the plurality of MR images to obtain a plurality of transformed MR images; and combining the plurality of transformed MR images to obtain the ensembled MR image; and outputting the ensembled MR image.Type: GrantFiled: May 5, 2023Date of Patent: October 1, 2024Assignee: Hyperfine Operations, Inc.Inventors: Jo Schlemper, Seyed Sadegh Mohseni Salehi, Michal Sofka
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Patent number: 12099105Abstract: Systems and methods are provided herein for determining whether to extend scanning performed by a magnetic resonance imaging (MRI) system. According to some embodiments, there is provided a method for imaging a subject using an MRI system, comprising: obtaining data for generating at least one magnetic resonance image of the subject by operating the MRI system in accordance with a first pulse sequence; prior to completing the obtaining the data in accordance with the first pulse sequence, determining to collect additional data to augment and/or replace at least some of the obtained data; determining a second pulse sequence to use for obtaining the additional data; and after completing the obtaining the data in accordance with the first pulse sequence, obtaining the additional data by operating the MRI system in accordance with the second pulse sequence.Type: GrantFiled: June 30, 2023Date of Patent: September 24, 2024Assignee: Hyperfine Operations, Inc.Inventors: Laura Sacolick, Carole Lazarus, Rafael O'Halloran, Hadrien A. Dyvorne
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Publication number: 20240272256Abstract: According to some aspects, a device configured to be coupled to a portable magnetic resonance imaging (MRI) device is provided, the device comprising at least one light source arranged to, when operated, project a visible boundary around at least a portion of the portable MRI device, wherein the visible boundary demarcates a region within which a magnetic field strength of a magnetic field generated by the portable MRI device equals or exceeds a threshold. The at least one light source may be arranged such that an angle of the at least one light source relative to the portable MRI device is adjustable and wherein adjusting the angle of the at least one light source relative to the portable MRI device changes a shape and/or size of the visible boundary.Type: ApplicationFiled: March 1, 2024Publication date: August 15, 2024Applicant: Hyperfine Operations, Inc.Inventors: Michael Stephen Poole, Michael Twieg, Anne Michele Nelson, Richard Q. Wang
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Patent number: 12053270Abstract: According to some aspects, a system configured to facilitate imaging an infant using a magnetic resonance imaging (MRI) device is provided herein. The system comprises an infant-carrying apparatus comprising an infant support configured to support the infant and an isolette for positioning the infant relative to the MRI device, the isolette comprising: a base for supporting the infant-carrying apparatus; and a bottom surface configured to be coupled to the MRI device. In some embodiments, the infant-carrying apparatus further comprises at least one radio frequency (RF) coil coupled to the infant support and configured to be coupled to the MRI device to detect MR signals during imaging performed by the MRI device. A method for positioning an infant relative to an MRI device using an infant-carrying apparatus and isolette is further provided herein.Type: GrantFiled: January 13, 2023Date of Patent: August 6, 2024Assignee: Hyperfine Operations, Inc.Inventors: Jacobus Coumans, Christopher Thomas McNulty
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Publication number: 20240255596Abstract: The present disclosure provides techniques for using opto-isolator circuitry to control switching circuitry configured to be coupled to a radio-frequency (RF) coil of a magnetic resonance imaging (MRI) system. In some embodiments, opto-isolator circuitry described herein may be configured to galvanically isolate switch controllers of the MRI system from the switching circuitry and/or provide feedback across an isolation barrier. Some embodiments provide an apparatus including switching circuitry configured to be coupled to an RF coil of an MRI system and a drive circuit that includes opto-isolator circuitry configured to control the switching circuitry. Some embodiments provide an MRI system that includes an RF coil configured to, when operated, transmit and/or receive RF signals to and/or from a field of view of the MRI system, switching circuitry coupled to the RF coil, and a drive circuit that includes opto-isolator circuitry configured to control the switching circuitry.Type: ApplicationFiled: September 13, 2023Publication date: August 1, 2024Applicant: Hyperfine Operations, Inc.Inventor: Michael Twieg
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Publication number: 20240257366Abstract: A computer-implemented method that includes providing as input to the neural network, a first image and a second image. The method further includes obtaining, using the neural network, a first transformed image based on the first image that may be aligned with the second image. The method further includes computing a first loss value based on a comparison of the first transformed image and the second image. The method further includes obtaining, using the neural network, a second transformed image based on the second image that may be aligned with the first image. The method further includes computing a second loss value based on a comparison of the second transformed image and the first image. The method further includes adjusting one or more parameters of the neural network based on the first loss value and the second loss value.Type: ApplicationFiled: March 20, 2024Publication date: August 1, 2024Applicant: Hyperfine Operations, Inc.Inventors: Neel Dey, Jo Schlemper, Seyed Sadegh Mohseni Salehi, Li Yao, Michal Sofka