Patents Assigned to I-SEN, INC.
  • Publication number: 20210007641
    Abstract: The present invention relates to a method of managing biometric information and, more particularly, a method of managing biometric information being capable of preventing the use of a sensor module of which an expiration date has expired, or a defective sensor module by determining the validity of a sensor module of a continuous biometric information measuring device on the basis of the generation date of sensor usage information or production lot information received from the continuous biometric information measuring device and preventing a reuse or a shared use of the sensor module on the basis of user information provided in a measurement message received from the continuous biometric information measurement device.
    Type: Application
    Filed: January 24, 2019
    Publication date: January 14, 2021
    Applicant: I-SENS, INC.
    Inventors: Jeong Je PARK, Jin Won LEE, Ji Seon NAH, Hyo Seon PARK, Jin Ho KIM, Ha Na LEE
  • Patent number: 10890557
    Abstract: The present disclosure relates to an electron transfer mediator comprising the osmium complex or a salt thereof, a reagent composition for an electrochemical biosensor, and an electrochemical biosensor, where the osmium compound or its salt maintains a stable oxidation-reduction form for an extended time period, a capacity to react with oxidoreductase being capable of performing the redox reaction of the target analytes, and no effect of oxygen partial pressure.
    Type: Grant
    Filed: December 31, 2015
    Date of Patent: January 12, 2021
    Assignee: I-SENS, INC.
    Inventors: In Jun Yoon, Jae Ho Shin, Yeon Ho Jung, Geun Sig Cha, Hakhyun Nam
  • Patent number: 10690619
    Abstract: A method for measuring a concentration of an analyte in a bio-sample using an electrochemical bio-sensor according to an exemplary embodiment of the present invention is characterized by a step of obtaining predetermined features from induced currents obtained by applying a DC voltage according to chronoamperometry in which, after a whole blood sample is injected to the electrochemical bio-sensor, a concentration of an analyte is obtained from an induced current obtained by applying a DC voltage for a certain time and from all induced currents obtained by further applying several step-ladder perturbation potentials for a short time subsequent to the DC voltage for the certain time, and is also characterized by minimization of a measurement error caused by a hindering material by forming a calibration equation by combining the at least one feature in a function and optimizing various conditions of the bio-sample through DeletedTextsmultivariable analysis.
    Type: Grant
    Filed: December 8, 2014
    Date of Patent: June 23, 2020
    Assignee: I-SENS, INC.
    Inventors: Geun Sig Cha, Hakhyun Nam, Seok-Won Lee, Sung Hyuk Choi, Youngjea Kang, Myeongho Lee, Ho Dong Park, Sung Pil Cho
  • Patent number: 10371709
    Abstract: A modular automatic analyzer using a circular type cartridge enabling centrifugation according to an exemplary embodiment of the present invention includes: a main body frame; an X-axis conveying unit which reciprocally moves in an X-axis direction with respect to the main body frame; a circular type cartridge accommodating housing which is installed with respect to the X-axis conveying unit so as to be reciprocally movable in the X-axis direction by the X-axis conveying unit, a single rotation drive unit which is installed in the circular type cartridge accommodating housing and is rotated step by step at a predetermined interval or rotated at a high speed for centrifugation, a circular type cartridge which is installed at an upper surface of the circular type cartridge accommodating housing so as to be rotatably connected to the rotation drive unit and has wells disposed to be spaced apart from each other at predetermined intervals in a circumferential direction of a disc-shaped main body, a tip lifting uni
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: August 6, 2019
    Assignee: I-SENS, INC.
    Inventors: Kyungho Kim, Jae Phil Do, Jaewon Jung, Jung Uk Ha, Sang Taek Shin, Seok-Won Lee, Yungjoon Jin, Yusung Kim
  • Patent number: 10371693
    Abstract: A portable blood glucose measurement device is provided. The device includes, in an externally exposed way, a temperature measurement medium of which the temperature quickly changes according to outside temperature changes provided on one side surface of a case. The device further includes an infrared temperature sensor. The device measures the temperature of the temperature measurement medium with the infrared temperature sensor in a noncontact manner, and calculates a blood glucose measurement result by considering the measured temperature so as to accurately reflect the outside temperature of an actual blood glucose measuring environment. The temperature measurement medium can be configured to sensitively respond to the outside temperature independently from the case such that the temperature of the temperature measurement medium, in accordance with the change in outside temperature, quickly and accurately changes so as to measure the temperature in a more accurate manner.
    Type: Grant
    Filed: May 22, 2015
    Date of Patent: August 6, 2019
    Assignee: I-SENS, INC.
    Inventors: Jin Won Lee, Chang Woo Ryu, Geun Sig Cha, Hak hyun Nam
  • Patent number: 10125384
    Abstract: The present invention relates to a stabilizing composition useful for improving the stability of reagent for redox reaction, and a reagent composition for redox reaction having an improved stability. The reagent composition for redox reaction can be applied for a reagent for electrochemical biosensor.
    Type: Grant
    Filed: January 25, 2013
    Date of Patent: November 13, 2018
    Assignee: I-SENS. INC.
    Inventors: Sung-Kwon Jung, Moon Hwan Kim, Eun Hye Im, Myeongho Lee, Ung Ki Lee, Geun Sig Cha, Hakhyun Nam
  • Patent number: 10024816
    Abstract: A personal blood glucose meter and a method for sensing abnormal measurement using the same are disclosed. A personal blood glucose meter includes: a sensor strip for collecting and applying a blood sample, wherein the sensor strip includes a reagent; an electrode unit including a plurality of electrodes for receiving the blood sample from the sensor strip to generate electric current based on potential differences; an MCU for measuring currents value generated from the electrode unit to determine whether a glucose value of the blood sample is normal or abnormal; a potential supply unit for applying a predetermined potential to the electrode unit; and a display unit displaying resultant output from the MCU.
    Type: Grant
    Filed: October 9, 2012
    Date of Patent: July 17, 2018
    Assignee: I-SENS, Inc.
    Inventors: Tae Eun Kim, Myeong-Ho Lee, Min Woo Suh, Geun Sig Cha, Hakhyum Nam
  • Patent number: 10000785
    Abstract: A composition of redox-reagent containing metal-containing complex and thionine or its derivative as electron transfer mediator for use in an electrochemical biosensor, and a biosensor containing the same are provided. With the increase in reaction rate between redox enzyme-thionine (or its derivative)-metal-containing complex in the composition of redox-reagent containing metal-containing complex and thionine or its derivative, glucose detection efficiency markedly increases, and the composition is hardly influenced from high humidity and interfering substances. Accordingly, the composition of redox-reagent is useful in fabricating an electrochemical biosensor for detecting glucose in blood.
    Type: Grant
    Filed: September 25, 2012
    Date of Patent: June 19, 2018
    Assignee: I-SENS, INC.
    Inventors: Sung-kwon Jung, Moon Hwan Kim, Myeong-Ho Lee, Ung-Ki Lee, Yeon-Ho Jung, Han-Be Park, Hakhyun Nam, Geun Sig Cha
  • Patent number: 9879362
    Abstract: The present invention relates to a method for producing nanofibers storing and transferring nitric oxide, and nanofibers produced thereby. The present invention may include: a filling step for filling a first material with nitric oxide; a synthesis step for synthesizing a second material having a functional group capable of covalently bonding to the first material; a sol-gel reaction step for carrying out a sol-gel reaction of the first material filled with nitric oxide with the second material to produce a gel; and an electrospinning step for electrospinning the gel to produce a nanofiber.
    Type: Grant
    Filed: March 7, 2014
    Date of Patent: January 30, 2018
    Assignee: I-SENS, INC.
    Inventors: Jae Ho Shin, Woo-Young Jung, Mingoo Kim, Jonghae Youn
  • Publication number: 20170350850
    Abstract: The present disclosure relates to an electron transfer mediator comprising the osmium complex or a salt thereof, a reagent composition for an electrochemical biosensor, and an electrochemical biosensor, where the osmium compound or its salt maintains a stable oxidation-reduction form for an extended time period, a capacity to react with oxidoreductase being capable of performing the redox reaction of the target analytes, and no effect of oxygen partial pressure.
    Type: Application
    Filed: December 31, 2015
    Publication date: December 7, 2017
    Applicant: I-SENS, INC.
    Inventors: In Jun YOON, Jae Ho SHIN, Yeon Ho JUNG, Geun Sig CHA, Hakhyun NAM
  • Publication number: 20170292967
    Abstract: A modular automatic analyzer using a circular type cartridge enabling centrifugation according to an exemplary embodiment of the present invention includes: a main body frame; an X-axis conveying unit which reciprocally moves in an X-axis direction with respect to the main body frame; a circular type cartridge accommodating housing which is installed with respect to the X-axis conveying unit so as to be reciprocally movable in the X-axis direction by the X-axis conveying unit, a single rotation drive unit which is installed in the circular type cartridge accommodating housing and is rotated step by step at a predetermined interval or rotated at a high speed for centrifugation, a circular type cartridge which is installed at an upper surface of the circular type cartridge accommodating housing so as to be rotatably connected to the rotation drive unit and has wells disposed to be spaced apart from each other at predetermined intervals in a circumferential direction of a disc-shaped main body, a tip lifting uni
    Type: Application
    Filed: April 7, 2017
    Publication date: October 12, 2017
    Applicant: I-SENS, INC.
    Inventors: Kyungho KIM, Jae Phil DO, Jaewon JUNG, Jung Uk HA, Sang Taek SHIN, Seok-Won LEE, Yungjoon JIN, Yusung KIM
  • Patent number: 9753004
    Abstract: The present invention relates to an electrochemical biosensor with improved hematocrit measurement accuracy for measuring blood glucose. According to the present invention, an electrochemical biosensor including a first electrode part for correcting a measured hematocrit value and a second electrode part for measuring a glucose concentration is effective in improving accuracy of a measured hematocrit value and in more improving accuracy of a measured blood glucose concentration using the measured hematocrit values for correction, because an insulation cover is made thinner than a working electrode and an auxiliary electrode, so that areas of a first working electrode and a first auxiliary electrode of the first electrode part exposed to a blood sample become equal; a distance between the first working electrode and the second working electrode becomes constant; and electrode areas are maintained constantly by the insulation cover even when a positioning error occurs during printing.
    Type: Grant
    Filed: December 1, 2014
    Date of Patent: September 5, 2017
    Assignee: I-Sens, Inc.
    Inventors: Myeong Ho Lee, Moon Hwan Kim, Ung Ki Lee, Han Be Park, Sung-Kwon Jung, Hakhyun Nam, Geun Sig Cha
  • Patent number: 9702842
    Abstract: Provided are an amperometric sensor and device for electrochemically quantifying nitrosothiol (RSNO), which is associated with storage and delivery of nitric oxide (NO) in the human body. The amperometric sensor for measuring a concentration of RSNO includes an electrode configured to measure an electric current generated by an oxidation reaction of NO, and a means configured to start and stop photo-induced decomposition of RSNO. Here, the electric current is measured by the oxidation reaction of NO before and after the photo-induced decomposition of RSNO. The amperometric sensor may measure separate signals of RSNO and NO, which are present in the sample at the same time, using one electrode, thereby preventing an inhibition action caused by NO during the measurement of RSNO. Also, the amperometric sensor is simple in structure and easy to manufacture and may be applied to manufacture of a small electrode, and thus may be developed as a sensor for in vivo measurements.
    Type: Grant
    Filed: April 14, 2011
    Date of Patent: July 11, 2017
    Assignee: I-SENS, INC.
    Inventors: Sung A Hong, Da Yeon Sung, Jun Hee Han, Jea Hun Song, Hakhyun Nam, Geun Sig Cha, Jae Ho Shin
  • Publication number: 20170188915
    Abstract: The present invention relates to a measurement error correction device of a bio-measurer and, more specifically, provides a measurement correction device which: enables a device for measuring a measurement error to be arranged inside a bio-measurer such that a measurement error can be corrected after the bio-measurer is manufactured; and enables a user to directly confirm, automatically or by the user's selection, whether the bio-measurer is normally operated at an early stage of the operation of the bio-measurer, thereby reducing the time and the cost for correcting a measurement error during a manufacturing process of the bio-measurer.
    Type: Application
    Filed: May 27, 2015
    Publication date: July 6, 2017
    Applicant: I-SENS, INC.
    Inventors: Tae Eun KIM, Jin Ho KIM, Hyo Seon PARK, Geun Sig CHA, Hak hyun NAM
  • Publication number: 20170138929
    Abstract: A portable blood glucose measurement device is provided. The device includes, in an externally exposed way, a temperature measurement medium of which the temperature quickly changes according to outside temperature changes provided on one side surface of a case. The device further includes an infrared temperature sensor. The device measures the temperature of the temperature measurement medium with the infrared temperature sensor in a noncontact manner, and calculates a blood glucose measurement result by considering the measured temperature so as to accurately reflect the outside temperature of an actual blood glucose measuring environment. The temperature measurement medium can be configured to sensitively respond to the outside temperature independently from the case such that the temperature of the temperature measurement medium, in accordance with the change in outside temperature, quickly and accurately changes so as to measure the temperature in a more accurate manner.
    Type: Application
    Filed: May 22, 2015
    Publication date: May 18, 2017
    Applicant: I-SENS, INC.
    Inventors: Jin Won LEE, Chang Woo RYU, Geun Sig CHA, Hak hyun NAM
  • Patent number: 9512458
    Abstract: Disclosed is an electrochemical biosensor having a sample introduction channel in which an insulator is employed to introduce a small amount of a sample uniformly and accurately and to adjust an area of a working electrode, thereby guaranteeing the accurate quantitative analysis of a sample. Provided with a sample collection barrier at a sample entrance, the biosensor allows a sample to be introduced at higher accuracy and to be analyzed with higher reproducibility and reliability.
    Type: Grant
    Filed: October 24, 2008
    Date of Patent: December 6, 2016
    Assignee: I-SENS, INC.
    Inventors: Gang Cui, Jae Hyun Yoo, Ju Yong Kim, Keun Ki Kim, Moon Hwan Kim, Hakhyun Nam, Geun Sig Cha
  • Patent number: 9435792
    Abstract: Disclosed is a hemolysis reagent composition for the quantitative analysis of glycated hemoglobin (HbAlc) via an enzymatic method. The hemolysis reagent compositions of the present invention containing a zwitterionic surfactant and a nitrous compound considerably accelerate hemolysis rate due to the presence of the zwitterionic surfactant, and also induce the N-terminal ?-chain of hemoglobin released by hemolysis to be exposed to the outside of the hemoglobin molecule and assists the participation of a greater number of molecules in the reaction, thereby improving reaction sensitivity and reaction rate of the glycated hemoglobin, and the nitrous compound makes the protein structure of the hemoglobin flexibly modified so that the amino acid sequence of the N-terminal ?-chain of hemoglobin can be readily cut off, thereby significantly reducing the entire time required for the measurement and improving the accuracy of the measurement.
    Type: Grant
    Filed: November 16, 2012
    Date of Patent: September 6, 2016
    Assignee: I-SENS, INC.
    Inventors: Dongxuan Shen, Joo Young Cho, Kap Soo Park, Geun Sig Cha, Hakhyun Nam
  • Patent number: 9351678
    Abstract: A lancet holder includes a holder body having a lancet seat at one end to mount a lancet and receiving the lancet and elastic fixing portions arranged in pairs to face each other on the inner side of the holder body so that the lancet received in the holder body is vertically held, and elastically fixing the lancet.
    Type: Grant
    Filed: September 20, 2011
    Date of Patent: May 31, 2016
    Assignee: I-SEN, INC.
    Inventors: Geun Sig Cha, Hakhyun Nam, Eun-Jong Cha, Kyung-Ah Kim
  • Patent number: 9316655
    Abstract: The present invention relates to a biochemical analysis cartridge having improved operability. More particularly, the present invention provides a biochemical analysis cartridge including an insertion-type sample cartridge and a reaction cartridge receiving the insertion-type sample cartridge, in which, as the sample cartridge is inserted into the reaction cartridge, a reaction solution chamber moves toward a broken part of a covertape so as to automatically supply the reaction solution stored in the chamber. The biochemical analysis cartridge having improved operability according to the present invention can induce the mixing between a sample and a reaction solution by simply inserting them into the reaction cartridge and a reaction thereafter, thereby minimizing the process of a measurer to intervene in the assay, and subsequently improving user convenience and operability.
    Type: Grant
    Filed: January 29, 2015
    Date of Patent: April 19, 2016
    Assignee: I-SENS, INC.
    Inventors: Geun Sig Cha, Hakhyun Nam, Dongxuan Shen, Joo Young Cho, Jihoon Kim
  • Patent number: 9267876
    Abstract: The present invention relates to a cell for optical analysis, wherein a flow space of a low depth is formed by attachment, using a simple double-coated tape without out special processing, of a micro flow channel through which a liquid sample passes, thereby enabling: a very easy manufacturing method; a reduction of manufacturing costs, thereby allowing the cell to be more widely used; a maintenance of a short path length of light with respect to the flow space in which the liquid sample flows, thereby enabling accurate optical analysis without diluting a sample with high absorbance; an expansion of a flow space region along the plane vertical to the light-passing direction, thereby enabling smoother optical analysis and improving the accuracy of optical analysis.
    Type: Grant
    Filed: June 21, 2012
    Date of Patent: February 23, 2016
    Assignee: I-SENS, INC.
    Inventors: Young Jae Kang, Tae Young Kang