Patents Assigned to I-SEN, INC.
-
Patent number: 8226004Abstract: A biosensor can be measured by a method that includes: determining malfunction of a production lot information sensing unit; alerting malfunction when the production lot information sensing unit malfunctions; encoding the production lot information through the production lot information sensing unit when the production lot information sensing unit does not malfunction; and detecting a component of a sample through a biosensor strip by using the encoded production lot information.Type: GrantFiled: November 11, 2008Date of Patent: July 24, 2012Assignee: i-SENS, Inc.Inventors: Geun Sig Cha, Hakhyun Nam, Gang Cui, Keun-Ki Kim, Shim-Ho Lee
-
Publication number: 20110210726Abstract: Disclosed are an electrochemical biosensor which comprises a production lot information identification portion, on which information is recorded in a magnetization mark, and a measuring device which can automatically identify the production lot information of the biosensor with the insertion of the electrochemical biosensor into the measuring device. The electrochemical biosensor and the measuring device thereof can record production lot information in the form of magnetization marks on an electrochemical biosensor strip and read the information as digital signals through a magnetoresistance sensor device, which can be mounted on the surface of a circuit board using Surface Mounted Technology (SMT). Without the need for a high-priced filter or a complicated calculation system, the magnetic detector system has a simple construction and realizes economic efficiency in the construction of the measuring device.Type: ApplicationFiled: February 26, 2008Publication date: September 1, 2011Applicant: I-SENS, INC.Inventors: Gang Cui, Keun Ki Kim, Dong Hoon Han, Moon Hwan Kim, Hakhyun Nam, Geun Sig Cha
-
Publication number: 20110147457Abstract: A biosensor can be measured by a method that includes: determining malfunction of a production lot information sensing unit; alerting malfunction when the production lot information sensing unit malfunctions; encoding the production lot information through the production lot information sensing unit when the production lot information sensing unit does not malfunction; and detecting a component of a sample through a biosensor strip by using the encoded production lot information.Type: ApplicationFiled: November 11, 2008Publication date: June 23, 2011Applicant: I-SENS, INC.Inventors: Geun Sig Cha, Hakhyun Nam, Gang Cui, Keun-Ki Kim, Shim-Ho Lee
-
Publication number: 20110011739Abstract: Disclosed is an electrochemical biosensor having a sample introduction channel in which an insulator is employed to introduce a small amount of a sample uniformly and accurately and to adjust an area of a working electrode, thereby guaranteeing the accurate quantitative analysis of a sample. Provided with a sample collection barrier at a sample entrance, the biosensor allows a sample to be introduced at higher accuracy and to be analyzed with higher reproducibility and reliability.Type: ApplicationFiled: October 24, 2008Publication date: January 20, 2011Applicant: I-SENS, INC.Inventor: Gang Cui
-
Publication number: 20100273248Abstract: The present invention provides a solution bag that is used for medical treatment and stores solution used for an apparatus for analyzing blood chemistry that measures and analyzes the concentrations of electrolytes, the partial pressures of gases, and the concentrations of metabolites or the volume ratio of red blood cells contained in blood.Type: ApplicationFiled: October 30, 2008Publication date: October 28, 2010Applicant: I-SENS, INC.Inventors: Jeonghan Ha, Heejun Lee, Tae Young Kang, Jungwon Shin, Hakhyun Nam, Geun Sig Cha
-
Publication number: 20100200428Abstract: Disclosed is a microfluidic sensor complex structure comprising a lower plate, a middle plate and an upper plate. A reference electrode, a working electrode and an electrode connection are formed on the lower plate. The middle plate comprises a microfluidic channel passage therein. The upper plate is overlaid on the middle plate so as to induce a capillary phenomenon on the microfluidic channel passage formed on in the middle plate. The microfluidic sensor complex structure allows the motion of a sample to be driven only by a capillary phenomenon, without additional operation, and allows an immune response, washing, and electrochemical analysis in one round once a sample is introduced thereinto. Hence, it requires only a short time period for measurement, is convenient to handle, and shows sensitivity and selectivity. Also, it can be produced on a mass scale because it can be formed of typical organic polymers using a simple method.Type: ApplicationFiled: July 24, 2008Publication date: August 12, 2010Applicants: I-SENS, INC., NANO-DITECH CORPORATIONInventors: Moon Hee Choi, Seung Hyeun Jung, Young Hoon Kim, Joo-Heon Park, Hakhyun Nam, Geun Sig Cha
-
Patent number: 7704747Abstract: Disclosed herein is a dual blood glucose meter. The dual blood glucose meter includes a meter body, a measurement strip, a variety of electronic parts and upper and lower strip receiving ports. The meter body is provided with a liquid crystal display panel on the front thereof to display measured numerical values and various pieces of pictorial information. The measurement strip is brought into contact with blood at a blood collection spot so as to measure blood glucose of the blood. The electronic parts are used to measure the blood glucose of the blood. The upper and lower strip receiving ports are formed at upper and lower ends of the meter body to receive the measurement strip, and are each electrically connected to the electric parts.Type: GrantFiled: April 15, 2004Date of Patent: April 27, 2010Assignee: i-SENS, Inc.Inventors: Moon Hwan Kim, Keun Ki Kim, Gang Cui, Hakhyun Nam, Geun-Sig Cha
-
Patent number: 7695608Abstract: An electrochemical biosensor and a biosensor measuring device. The electrochemical biosensor includes a plurality of electrodes, capillary sample cell portions, reaction reagent layers, electrode connection portions, and a production lot information identification portion. The production lot information identification portion is configured such that the production lot information is recorded thereon has one or more infrared absorption/reflection marks, which indicate information about differences between production lots through the printing and/or attachment of colored or colorless materials, having differences in absorbency or reflectivity of infrared rays, in conformity of a predetermined pattern or through the attachment of transparent films.Type: GrantFiled: May 14, 2007Date of Patent: April 13, 2010Assignee: i-SENS, Inc.Inventors: Keun Ki Kim, Jae Hyun Yoo, Gang Cui, Moon Hwan Kim, Hakhyun Nam, Geun Sig Cha
-
Publication number: 20090308744Abstract: Disclosed relates to an electrochemical determination system of glycated proteins, the system comprising: a filtering means for filtering labeled compounds bound to glycated proteins and non-glycated proteins after adding labeling compounds, capable of selectively binding to the glycated proteins to a solution, in which glycated/non-glycated proteins coexist, to be bound all to the glycated proteins; and a quantifying means for quantifying the filtered labeling compounds, not bound to the glycated proteins. The system of the present invention filters the residual labeled compounds left after binding to glycated proteins to quantify, instead of directly quantifying glycated proteins via the known glycated protein determination methods, thus simplifying the configuration of the system that can provide exact determinations with a low cost.Type: ApplicationFiled: July 29, 2006Publication date: December 17, 2009Applicant: I-SENS, INC.Inventors: Hakhyun Nam, Fenghua Zhang, Soon Hye Yang, Bo Kyeong Kang, Gang Cui, Moon Hee Choi, Joung Su Lee, Geun Sig Cha
-
Patent number: 7455756Abstract: A biosensor, for use in measurement of an analyte, includes a microporous membrane support, a first electrode system, a second electrode system, and a pair of insulating films. The first electrode system is formed on the surface of the microporous membrane support and the second electrode system is formed on the opposite surface of the microporous membrane support. The biosensor enables a rapid, simple, separation-free, and selective detection of the analytes. The biosensor does not require any bulky additional electrode, so that miniaturization, point-of-car testing, and disposability can be achieved.Type: GrantFiled: May 30, 2002Date of Patent: November 25, 2008Assignee: i-SENS, Inc.Inventors: Moon-Hee Choi, Gang Cui, Jae-Hyun Yoo, Ho-Choll Cho, Min-Sun Kim, Fenghua Zhang, Hakhyun Nam, Geun-Sig Cha
-
Publication number: 20080237062Abstract: An electrochemical biosensor and a biosensor measuring device. The electrochemical biosensor includes a plurality of electrodes, capillary sample cell portions, reaction reagent layers, electrode connection portions, and a production lot information identification portion. The production lot information identification portion is configured such that the production lot information is recorded thereon has one or more infrared absorption/reflection marks, which indicate information about differences between production lots through the printing and/or attachment of colored or colorless materials, having differences in absorbency or reflectivity of infrared rays, in conformity of a predetermined pattern or through the attachment of transparent films.Type: ApplicationFiled: May 14, 2007Publication date: October 2, 2008Applicant: I-SENS, INC.Inventors: Keun Ki Kim, Jae Hyun Yoo, Gang Cui, Moon Hwan Kim, Hakhyun Nam, Geun Sig Cha
-
Patent number: 7288174Abstract: There is provided the reagent layer composition that can substantially reduce the measurement bias arising from hematocrits. The addition of fatty acid (4-20 carbons) and quaternary ammonium salt to a commonly used reagent layer composition composed of an enzyme, an electron transfer mediator, and several water soluble polymers not only reduce the hematocrit level-dependent bias but also provide very stable performance for an extended period of time. Disclosed are also various types of sub microliter sample volume electrochemical biosensors that are suitable to use with the reagent layer composition of present invention.Type: GrantFiled: February 12, 2004Date of Patent: October 30, 2007Assignee: i-SENS, Inc.Inventors: Gang Cui, Jae-Hyun Yoo, Moon-Hwan Kim, Ju-Yong Kim, Jung-Hee Uhm, Hakhyun Nam, Geun-Sig Cha
-
Patent number: 7258769Abstract: There is provided electrochemical biosensors with a sample introducing part, comprising a sample introducing passage, an air discharge passage, and a void. The sample introducing passage communicates with the air discharge passage, and the void is formed at the point of communication. Also, disclosed is the electrochemical biosensor with the said sample introducing part and a fluidity determining electrode.Type: GrantFiled: April 17, 2002Date of Patent: August 21, 2007Assignee: I-Sens, Inc.Inventors: Gang Cui, Ju-Yong Kim, Moon-Hwan Kim
-
Patent number: 6746583Abstract: There is provided a microchip-based differential-type carbon dioxide gas sensor for detecting dissolved carbon dioxide levels. It functions with at least one working electrode composed of an unbuffered hydrogel membrane containing a certain amount of sodium bicarbonate and a pH-sensitive gas-permeable membrane; and a reference electrode composed of a buffered hydrogel membrane and a pH-sensitive gas-permeable membrane. The unbuffered hydrogel membrane contains carbonic anhydrase, which reduces the time period for the hydration of carbon dioxide, thereby allowing the quick measurement of the level of carbon dioxide. In addition to being significantly improved in stabilization, sensing, and recovering time periods, the differential-type carbon dioxide gas sensor can be fabricated in small sizes and quickly measure levels of carbon dioxide dissolved in sample solution.Type: GrantFiled: June 8, 2001Date of Patent: June 8, 2004Assignee: i-Sens, Inc.Inventors: Jae Seon Lee, Jae Ho Shin, Min Hyung Lee, Hakhyun Nam, Geun Sig Cha
-
Patent number: 6726818Abstract: Disclosed is a porous membrane built-in biosensor comprising (a) at least one substrate; (b) an electrode layer patterned on the substrate, consisting of an electrode system and a circuit connector; (c) an insulator, formed on parts of the electrode layer, for electrically separating the electrode system from a circuit connector; and (d) a porous membrane via the insulator on the electrode system, wherein, when a whole blood sample is introduced to the biosensor, the whole blood sample is separated into its components during the chromatographic motion through the porous membrane so that only blood plasma can be contacted with the electrode system. The porous membrane built-in biosensor is provided with a sample inlet, which allows samples to be introduced in a constant quantity to the biosensors porous membranes without pretreatment.Type: GrantFiled: July 13, 2001Date of Patent: April 27, 2004Assignee: i-Sens, Inc.Inventors: Gang Cui, Jae Hyun Yoo, Byung Wook Woo, Moon Hwan Kim, Hyun Joon Oh, Hakhyun Nam, Geun Sig Cha
-
Patent number: 6663756Abstract: Disclosed is a microchip-based differential-type potentiometric oxygen gas sensor, which comprises a working electrode and a reference electrode. The working electrode is composed of a cobalt-plated electrode, a buffered hydrogel, and an ion sensitive gas permeable membrane while the reference electrode is composed of an oxygen non-sensitive silver chloride electrode and the same ion-selective gas-permeable membrane of working electrode. By taking advantage of the corrosion potential, the microchip-based oxygen gas sensor can accurately and quickly detect the content of dissolved oxygen in a sample solution. With this structure, the oxygen gas sensor is applied to a microchip-based all potentiometric multi-sensor capable of detecting two or more ions and gas species on a single chip.Type: GrantFiled: October 18, 2001Date of Patent: December 16, 2003Assignee: i-Sens Inc.Inventors: Dong Kwon Lee, Tae Young Kang, Sung Hyuk Choi, Jae Seon Lee, Hakhyun Nam, Geun Sig Cha
-
Patent number: 6509148Abstract: Disclosed is a method for fabricating biosensors, using hydrophilic polyurethane. Bio-active reagents, including enzymes, antibodies, antigens, cells and receptors, are mixed with hydrophilic polyurethane and the mixture is directly coated over a signal transducer to form a sensing film which serves as a signal detector. The method using hydrophilic polyurethane allows the simplification of the fabrication of biosensors without conducting complicated chemical reactions and washing steps, such as crosslinking. The bio-active reagent entrapped within the hydrophilic polyurethane film can retains its high activity for an extended period of time and the intrinsic potentiometric response of the underlying ion-selective polymeric membrane is not affected by the bio-active reagent immobilized polyurethane film coated on its sensing surface. Therefore, the biosensors are superior in specificity, selectivity, and stability.Type: GrantFiled: February 10, 2000Date of Patent: January 21, 2003Assignee: i-Sens, Inc.Inventors: Geun Sig Cha, Hakhyun Nam, Jae Ho Shin