Abstract: Targeting molecules are provided for use in delivering imaging agents to epithelial tissue. The targeting molecule comprises a polypeptide that forms a closed covalent loop, contains at least three peptide domains having ?-sheet character, each of the domains being separated by domains lacking ?-sheet character. The targeting molecule specifically binds to a basolateral factor attached to a basolateral domain of an epithelial cell surface causing internalization of a linked imaging agent into the cells. The polypeptide or imaging agent may be linked to a peptide amino acid sequence that directs delivery of the imaging agent to a carcinoma cell, a nucleus, or an endoplasmic reticulum.

Abstract: An asymmetric multi-layer insulative film of improved internal adhesive strength is made by combining a layer of polyimide and a high-temperature bonding layer, the high-temperature bonding layer being derived from a high temperature base polymer made of poly(tetrafluoroethylene-co-perfluoro[alkyl vinyl ether]) (PFA) and optionally blended with from 0–60 weight percent poly(tetrafluoroethylene-co-hexafluoropropylene) (FEP). The polyimide and high-temperature bonding layer laminate optionally also contains a layer of unsintered, partially sintered, or totally sintered polytetrafluoroethylene (PTFE) bonded directly to the high-temperature bonding layer. In addition, the polyimide high-temperature bonding layer laminate may be adhered to a poly(tetrafluoroethylene-co-hexafluoropropylene) (FEP) adhesive primer layer to more effectively bond the polyimide core layer to the high-temperature bonding layer.

Abstract: Improved suspensions of transition metal complexes of 2,6-diacylpyridine(bisimines) or 2,6-pyridinedicarboxaldehyde(bisimines), which are useful in catalysts for the polymerization or oligomerization of olefins, are prepared by sonicating a mixture of one or more of these complexes and an inert liquid. The resulting suspensions can be directly used as olefin polymerization or oligomerization catalyst components in oligomerization or polymerization processes. These processes may produce, for example, polyolefins useful for molding resins or films, or linear ?-olefins.

Abstract: This invention relates to an isolated nucleic acid fragment encoding a plant enzyme that catalyze steps in the biosynthesis of lysine, threonine, methionine, cysteine and isoleucine from aspartate, the enzyme a member selected from the group consisting of: dihydrodipicolinate reductase, diaminopimelate epimerase, threonine synthase, threonine deaminase and S-adenosylmethionine synthetase. The invention also relates to the construction of a chimeric gene encoding all or a portion of the enzyme, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the enzyme in a transformed host cell.

Abstract: A centrifuge for separating feed material into component parts, in one aspect primarily solid and primarily liquid parts, the centrifuge, in certain aspects, including a conveyor rotatably mounted in a rotatable housing, the conveyor having an interior and at least one impeller, the rotatable housing having a separating region with a pool area and a beach area with feed material passable through the interior of the conveyor, the feed material directed radially by the impeller(s) and spread by the impeller(s), in certain aspects along the conveyor or part thereof, onto part of the pool area, and/or in certain aspects onto the beach area.

Abstract: A process for producing a structure of a thin layer of semiconductor material obtained from a composite structure donor wafer. The donor wafer includes a lattice parameter matching layer of a matching substrate that advantageously has an upper layer of semiconductor material having a first lattice parameter. A film of semiconductor material having a second, nominal, lattice parameter that is substantially different from the first lattice parameter is strained by the matching layer. A region of weakness is created in the matching substrate to facilitate splitting. A relaxed layer has a nominal lattice parameter that is substantially identical to the first lattice parameter. The relaxed layer is transferred to a receiving substrate. A number of different wafers can be made by this process.

Abstract: A dispenser for storing and dispensing small items is provided. The dispenser includes a base container having an a hollow space for storing items to be dispensed, a cover sized to fit over the opening of the base container, and a wheel rotationally mounted under the cover which has a shaft and at least three fins radially extending from the shaft and spaced from each other around the shaft. The wheel is mounted under the cover such that the fins of the wheel can rotate under the cover and carry an item stored within the base container to a port in the cover. The rotating fins on the wheel are aligned so as to contact and pass over the raised boss on an inside surface of the cover each time the wheel is rotated 360 degrees. An actuator is also provided for manually rotating the wheel under the cover, which actuator is accessible from outside of the dispenser. Both the cover and the fins of the wheel are made of plastic.

Abstract: A method for implanting atomic species through an uneven surface of a semiconductor layer. The technique includes applying a covering layer upon the uneven surface in an amount sufficient and in a manner to increase surface uniformity. The method also includes implanting atomic species through the covering layer and uneven surface to obtain a more uniform depth of implantation of the atomic species in the layer.

Abstract: A process for making a radiation filter element comprises the steps of: exposing part of an assemblage to infrared radiation, the assemblage comprising a donor comprising (1) a support capable of transmitting infrared light, and (2) a transferable layer comprising a transferable material and an infrared-absorbing dye, the transferable layer of the donor being in contact with a receiver to provide an exposed assemblage comprising an exposed part of the transferable layer and an unexposed part of the transferable layer; separating the receiver and the support of the exposed assemblage to obtain an imaged receiver and a spent donor, wherein the imaged receiver comprises the receiver, a transferred portion of the transferable material and a transferred portion of the infrared-absorbing dye, said transferred portion of the IR dye having a color and the spent donor comprises the support and a retained portion of the transferable layer; and heating the transferred portion of the transferable material and the transfe

Abstract: Method of repairing defective areas in a stoving lacquer coating, in which the defective area ready for repair lacquering is coated with a powder coating composition or with an aqueous powder coating slurry, and the applied powder coating is then melted and cured by irradiation with near infrared radiation (NIR).

Abstract: Fluorinated copolymers useful in photoresist compositions and associated processes for microlithography are described. These copolymers are comprised of a fluoroalcohol or protected fluoroalcohol functional group which simultaneously imparts high ultraviolet (UV) transparency and developability in basic media to these materials and a repeat unit derived from an acrylate monomer containing a fluoroalkyl group or a hydroxyl substituted alkyl group. The materials of this invention have high UV transparency, particularly at 193 and 157 nm, which makes them highly useful for lithography at these short wavelengths.

Abstract: The invention provides an apparatus for splitting a substrate apart, the substrate comprising two adjoining wafers defining between them a cleavage plane, the apparatus being characterized in that it comprises: means for feeding splitter means with a plurality of substrates disposed in a substrate-storage direction; splitter means for splitting apart wafers of the substrates, the splitter means comprising moving jaws; and means for performing controlled displacement of certain substrate wafers after they have been split apart in a direction that is substantially parallel to the substrate-storage direction, whereby the apparatus is suitable for splitting apart the plurality of substrates. The invention also provides an associated splitting method.

Abstract: An aqueous coating composition having a pH of 6.0–10.0 comprises 30% to 70% by weight of film-forming binder and correspondingly 70% to 30% by weight of an aqueous liquid carrier for the binder; wherein the binder comprises a. 20% to 95% by weight, based on the weight of the binder, of a urethane oligomer having a weight average molecular weight of 300 to 2500 and having acid functionality and neutralized with an amine and to form a water-dispersible product; and b. 5% to 80% by weight, based on the weight of the binder, of a water-compatible alkylated melamine formaldehyde crosslinking agent; finishes formed from the composition have good gloss and distinctness of image and excellent acid etch and mar resistance.

Abstract: Liquid coating compositions and methods for formulating the same are disclosed. The compositions comprise the combination of an epoxy-functional silane, a multipodal silane, and a strong acid dispersed within a solvent. The liquid coating compositions are formulated to be applied to a substrate and thereafter cured. The resultant coating is transparent and abrasion-resistant. The coating may include additional additives or may be specifically formulated to possess specific properties as may be desired for a specific application. Such coating compositions can further be formulated such that the refractive index thereof can be adjusted to correspond to the refractive index of the substrate to which the liquid coating compositions are applied.

Abstract: The invention relates to methods of forming a relaxed or pseudo-relaxed layer on a substrate, wherein the relaxed layer may be a semiconductor material. An implementation of the method includes growing an elastically stressed semiconductor material layer on a donor substrate, forming a glassy layer of a viscous material and bonding it to the stressed layer, removing a portion of the donor substrate to form a structure that includes the glassy layer, the stressed layer and a surface layer of donor substrate, and then heat treating the structure at a temperature of at least a viscosity temperature of the glassy layer to relax the stressed layer. The glassy layer can also be bonded to a receiving substrate so that the structure can be transferred thereto. Implementations also relate to structures obtained from the method.

Abstract: A bi-directional relationship manager is described for setting a new reference value for managing bi-directional relationships between objects in an object model. The bi-directional relationship manager receives bi-directional relationship information indicating interrelation between objects having one or more bi-directional relationships. It creates proxy objects based on the bi-directional relationship information for selected bi-directional relationship objects having bi-directional relationships. A created proxy object receives a new reference value to be set in a selected object relating to a bi-directional relationship. It determines, using one or more of the proxy objects, a new peer value to be set in a peer object which has the bi-directional relationship with the selected object, and sets the new peer value to a proxy object created for the peer object.

Abstract: A method of producing a substrate that has a transfer crystalline layer transferred from a donor wafer onto a support. The transfer layer can include one or more foreign species to modify its properties. In the preferred embodiment an atomic species is implanted into a zone of the donor wafer that is substantially free of foreign species to form an embrittlement or weakened zone below a bonding face thereof, with the weakened zone and the bonding face delimiting a transfer layer to be transferred. The donor wafer is preferably then bonded at the level of its bonding face to a support. Stresses are then preferably applied to produce a cleavage in the region of the weakened zone to obtain a substrate that includes the support and the transfer layer. Foreign species are preferably diffused into the thickness of the transfer layer prior to implantation or after cleavage to modify the properties of the transfer layer, preferably its electrical or optical properties.

Abstract: The DNA of the invention are characterised in that they concern the whole or part of genes, with their reading frame, to be found in Neisseria meningitidis, but not in Neisseria gonorrhoeae, or in Neisseria lactamica except the genes involved in the biosynthesis of the polysaccharide capsule, frp A, frp C, opc, por A, rotamase the sequence IC1106, IgA protease, pilline, pilC, transferrin binding proteins and opacity proteins. The invention also concerns the polypeptides corresponding to these DNA and the antibodies directed against these polypeptides. It is applicable in the prevention and the detection of meningococcus induced infections and meningitis.