Patents Assigned to Illinois, University of
  • Patent number: 12270040
    Abstract: The present invention is directed to a transgenic soybean plant having increased oleic acid content comprising a polynucleotide comprising a fatty acid thioesterase (FAT) related promoter that functions in the soybean plant operably linked to a polynucleotide encoding a polypeptide having FAT activity. The invention is further directed to a method of increasing oleic acid content of a soybean plant comprising transforming a soybean plant with a polynucleotide comprising a fatty acid thioesterase (FAT) related promoter that functions in the soybean plant operably linked to a polynucleotide encoding a polypeptide having FAT activity.
    Type: Grant
    Filed: May 27, 2022
    Date of Patent: April 8, 2025
    Assignee: Board of Trustees of Southern Illinois University
    Inventors: Khalid Meksem, Naoufal Lakhssassi, Dounya Knizia, Zhou Zhou
  • Patent number: 12270039
    Abstract: The present invention is directed to a transgenic soybean plant with increased oleic acid content comprising a polynucleotide encoding a fatty acid desaturase (FAD) related promoter that functions in the soybean plant operably linked to a polynucleotide encoding a polypeptide having FAD activity. The invention is also related to a plant of an agronomically elite soybean variety with increased oleic acid content comprising a polynucleotide encoding a fatty acid desaturase (FAD) related promoter that functions in the soybean plant operably linked to a polynucleotide encoding a polypeptide having FAD activity. The invention is still further directed to a method of increasing the oleic acid content of a soybean plant comprising transforming the soybean plant with a polynucleotide encoding a fatty acid desaturase (FAD) related promoter that functions in the soybean plant operably linked to a polynucleotide encoding a polypeptide having FAD activity.
    Type: Grant
    Filed: May 16, 2022
    Date of Patent: April 8, 2025
    Assignee: Board of Trustees of Southern Illinois University
    Inventors: Khalid Meksem, Naoufal Lakhssassi, Dounya Knizia
  • Patent number: 12251537
    Abstract: A syringe device and methods for device for separating liquids of different densities are provided where the syringe device includes a hollow syringe barrel, a perforated plunger seal with a seal hole, and a hollow plunging tube with a closed bottom with at least one tube hole.
    Type: Grant
    Filed: August 4, 2020
    Date of Patent: March 18, 2025
    Assignee: Board of Trustees of Southern Illinois University
    Inventors: Ashim Gupta, Michael W. Neumeister, Sohyung Cho, Scott Moore, Robert B. Zajeski, Jr.
  • Patent number: 12231857
    Abstract: A method for personalized sound modification, with a personal sound system having a microphone; a user device which includes a processor, computer readable medium, and optionally the microphone; and a sound output device; is provided. The method includes: providing a user hearing profile including lower and upper limits of the user's auditory dynamic range at a plurality of sound frequencies, prepared with the personal sound system; receiving a sound signal from the microphone; optionally separating the sound signal into a plurality of frequency channels; amplifying or attenuating sound frequencies in the sound signal which have a volume level outside the lower or upper limits of the user's auditory dynamic range, respectively, and forming a modified sound signal with which the sound output device will produce sounds within the user's auditory dynamic range; and providing the modified sound signal to the sound output device.
    Type: Grant
    Filed: May 6, 2022
    Date of Patent: February 18, 2025
    Assignee: Board of Trustees of Northern Illinois University
    Inventor: King Chung
  • Publication number: 20250039613
    Abstract: A flexible conductive hearing aid, comprises: (i) a flexible substrate, (ii) components, on or in the flexible substrate, including (a) a microphone, configured to produce an electrical signal from sound, (b) electronic circuits, connected to the microphone, configured to amplifying the electrical signal, (c) an actuator, connected to the electronic circuits, configures to produce vibrations in the flexible substrate from the amplified electrical signal, and (d) a power source, connected to the microphone and the electrical circuits. Furthermore, the flexible conductive hearing aid comprise (iii) optionally, a flexible top layer, on the components, and (iv) optionally, a flexible bottom layer, wherein the flexible substrate is on the flexible bottom layer.
    Type: Application
    Filed: December 8, 2022
    Publication date: January 30, 2025
    Applicant: Board of Trustees of Northern Illinois UNiversity
    Inventor: S. Mohammad J. Moghimi
  • Publication number: 20250023128
    Abstract: A process for charging a discharged electrochemical cell includes applying a voltage bias to the discharged electrochemical cell; and illuminating the cathode, the anode, or both the cathode and the anode with light having a narrow band of wavelengths corresponding to the respective band gaps of the electrode active materials.
    Type: Application
    Filed: July 5, 2024
    Publication date: January 16, 2025
    Applicants: UChicago Argonne, LLC, New York University, Northern Illinois University
    Inventors: Christopher S. Johnson, Yingwen Cheng, Bowen AN, Yaxin Shen, Andre Taylor, Jason Lipton, Yuanyuan MA
  • Patent number: 12162935
    Abstract: Compositions and treatment regimen that includes the compositions, suitable for preventing, treating and restoring hearing acuity in a subject are provided. The treatment regimen includes an amount of capsaicin and an amount of a TNF-? inhibitor (such as etanercept) that are delivered relatively simultaneously to a subject. Methods of providing a pretreatment to a subject suitable for preventing hearing loss are also provided. The capsaicin and TNF? inhibitor may be provided in different delivery forms to the subject. Methods of providing a treatment for hearing loss with a TNF? inhibitor alone, such as entanercept, or with capsaicin alone, are also provided.
    Type: Grant
    Filed: February 8, 2021
    Date of Patent: December 10, 2024
    Assignee: Board of Trustees of Southern Illinois University
    Inventors: Debashree Mukherjea, Vickram Ramkumar, Leonard Rybak
  • Patent number: 12155075
    Abstract: A pyrolyzed MOF catalyst for in the carbon dioxide reduction reaction and methods of making the catalyst. The catalysts are composed of highly porous transition metal organic frameworks exhibiting large pores with regular distribution of transition metals within the structure.
    Type: Grant
    Filed: March 12, 2021
    Date of Patent: November 26, 2024
    Assignees: UChicago Argonne, LLC, Board of Trustees of Northern Illinois University
    Inventors: Di-Jia Liu, Dominic Rebollar
  • Patent number: 12133762
    Abstract: A system for patient cardiac imaging and tissue modeling. The system includes a patient imaging device that can acquire patient cardiac imaging data. A processor is configured to receive the cardiac imaging data. A user interface and display allow a user to interact with the cardiac imaging data. The processor includes fat identification software conducting operations to interact with a trained learning network to identify fat tissue in the cardiac imaging data and to map fat tissue onto a three-dimensional model of the heart. A preferred system uses an ultrasound imaging device as the patient imaging device. Another preferred system uses an MRI or CT image device as the patient imaging device.
    Type: Grant
    Filed: April 27, 2022
    Date of Patent: November 5, 2024
    Assignee: Board of Trustees of Southern Illinois University
    Inventors: Jon Klingensmith, Colin Gibbons, Michaela Kulasekara, Vu Quang Dinh
  • Patent number: 12106908
    Abstract: The present disclosure relates to a device that includes a first layer having an active material and a stabilizing material, where the active material includes a semiconductor, the stabilizing material includes at least one of an oligomer, an elastomer, a polymer, and/or a resin, and the stabilizing material provides to the device an improved performance metric compared to a device constructed of the first layer but constructed of only the active material (i.e., in the absence of the stabilizing material).
    Type: Grant
    Filed: April 25, 2023
    Date of Patent: October 1, 2024
    Assignees: Alliance for Sustainable Energy, LLC, Board of Trustees of Northern Illinois University
    Inventors: Kai Zhu, Fei Zhang, Tao Xu
  • Patent number: 11918588
    Abstract: A method for treating a subject with symptoms of tinnitus and pharmaceutical compositions for treating tinnitus, the pharmaceutical compositions comprising one or more of the following: sazetidine, a pharmaceutically acceptable salt of sazetidine, varenicline, a pharmaceutically acceptable salt of varenicline, or any combination thereof.
    Type: Grant
    Filed: February 6, 2020
    Date of Patent: March 5, 2024
    Assignee: Board of Trustees of Southern Illinois University
    Inventors: Donald Caspary, Thomas Brozoski, Brandon Cox
  • Patent number: 11912687
    Abstract: The present disclosure describes novel compounds that are somatostatin receptor type 4 agonists.
    Type: Grant
    Filed: September 3, 2021
    Date of Patent: February 27, 2024
    Assignee: Board of Trustees of the Southern Illinois University
    Inventors: Kenneth A. Witt, Albert M. Crider, William Neumann, Audrey Hospital, Karin Sandoval, Maria Kontoyianni
  • Patent number: 11846033
    Abstract: An iron-containing Chevrel phase material, contains iron and Mo6S8 clusters, in particular an iron-containing Chevrel phase material having a formula FexMo6S8, wherein 2?x?4. The iron-containing Chevrel phase provides an efficient catalyst for the electrochemical production of ammonia from water and nitrogen gas.
    Type: Grant
    Filed: May 18, 2021
    Date of Patent: December 19, 2023
    Assignee: Board of Trustees of Northern Illinois University
    Inventors: Yingwen Cheng, Ke Lu
  • Patent number: 11834416
    Abstract: The present disclosure is directed to a cleavable agent for enhanced magnetic resonance generally corresponding to the formula Y-L-R, wherein Y represents a catalyst-binding moiety having at least one isotopically labeled heteroatom, L represents a cleavable bond, and R represents a hyperpolarized payload having at least one isotopically labeled carbon. Also disclosed herein is a method of cleaving the cleavable agent for enhanced magnetic resonance.
    Type: Grant
    Filed: November 27, 2019
    Date of Patent: December 5, 2023
    Assignees: Board of Trustees of Southern Illinois University, Vanderbilt University
    Inventors: Boyd M. Goodson, Eduard Y. Chekmenev, Bryce E. Kidd, Jamil A. Mashni, Miranda Limbach, Yuqing Hou, Fan Shi
  • Patent number: 11753422
    Abstract: The present disclosure relates to a composition that includes a material of at least one of a perovskite structure, a perovskite-like structure, and/or a perovskitoid structure, where the material includes an isotope of an element, the isotope has more neutrons than protons, and the isotope is incorporated into the perovskite structure, the perovskite-like structure, and/or the perovskitoid structure. In some embodiments of the present disclosure, the isotope may make up between greater than 0% and 100% of the element.
    Type: Grant
    Filed: August 19, 2021
    Date of Patent: September 12, 2023
    Assignees: Alliance for Sustainable Energy, LLC, Board of Trustees of Northern Illinois University
    Inventors: Kai Zhu, Jinhui Tong, Tao Xu, Xun Li
  • Patent number: 11682530
    Abstract: The present disclosure relates to a device that includes a first layer having an active material and a stabilizing material, where the active material includes a semiconductor, the stabilizing material includes at least one of an oligomer, an elastomer, a polymer, and/or a resin, and the stabilizing material provides to the device an improved performance metric compared to a device constructed of the first layer but constructed of only the active material (i.e., in the absence of the stabilizing material).
    Type: Grant
    Filed: November 3, 2021
    Date of Patent: June 20, 2023
    Assignees: Alliance for Sustainable Energy, LLC, Board of Trustees of Northern Illinois University
    Inventors: Kai Zhu, Fei Zhang, Tao Xu
  • Patent number: 11677072
    Abstract: An anode of a battery comprises lithium metal, and a dopant, in the lithium metal. The anode has a thickness of at most 50 ?m, and the dopant is a metal with an electronegativity greater than lithium.
    Type: Grant
    Filed: November 23, 2021
    Date of Patent: June 13, 2023
    Assignee: Board of Trustees of Northern Illinois University
    Inventors: Yingwen Cheng, Tao Xu, Ke Lu, Haiping Xu
  • Publication number: 20230151378
    Abstract: The present invention is directed to a transgenic soybean plant having increased seed protein content and/or increased seed oil content comprising a polynucleotide encoding a ?-ConGlycinin soybean seed storage promoter that functions in the soybean plant operably linked to a polynucleotide encoding a soybean seed storage polypeptide having ?-ConGlycinin activity. The invention is further directed to a method of increasing seed protein content and/or increasing seed oil content of a soybean plant comprising transforming the soybean plant with a polynucleotide encoding a ?-ConGlycinin soybean seed storage promoter that functions in the soybean plant operably linked to a polynucleotide encoding a soybean seed storage polypeptide having ?-ConGlycinin activity.
    Type: Application
    Filed: October 28, 2022
    Publication date: May 18, 2023
    Applicant: Board of Trustees of Southern Illinois University
    Inventors: Khalid Meksem, Naoufal Lakhssassi
  • Publication number: 20230150943
    Abstract: The present disclosure is directed to a cleavable agent for enhanced magnetic resonance generally corresponding to the formula Y-L-R, wherein Y represents a catalyst-binding moiety having at least one isotopically labeled heteroatom, L represents a cleavable bond, and R represents a hyperpolarized payload having at least one isotopically labeled carbon. Also disclosed herein is a method of cleaving the cleavable agent for enhanced magnetic resonance.
    Type: Application
    Filed: January 4, 2023
    Publication date: May 18, 2023
    Applicants: Board of Trustees of Southern Illinois University, Vanderbilt University
    Inventors: Boyd M. Goodson, Eduard Y. Chekmenev, Bryce E. Kidd, Jamil A. Mashni, Miranda Limbach, Yuqing Hou, Fan Shi
  • Patent number: 11571686
    Abstract: The present disclosure provides a method that embodies a simple and effective route to remove homogeneous catalysts from solutions wherein NMR/MRI signal amplification by reversible exchange (SABRE) or parahydrogen-induced polarization (PHIP) is performed. A method for recovering a homogeneous SABRE/PHIP catalyst for reuse is also described.
    Type: Grant
    Filed: February 17, 2020
    Date of Patent: February 7, 2023
    Assignees: Board of Trustees of Southern Illinois University, Vanderbilt University, The Regents of the University of California
    Inventors: Boyd M. Goodson, Eduard Y. Chekmenev, Igor V. Koptyug, Kirill V. Kovtunov, Roman V. Shchepin, Bryce E. Kidd, Jonathan Gesiorski, Max E. Gemeinhardt, Danila A. Barskiy