Patents Assigned to Illinois, University of
  • Publication number: 20230151378
    Abstract: The present invention is directed to a transgenic soybean plant having increased seed protein content and/or increased seed oil content comprising a polynucleotide encoding a ?-ConGlycinin soybean seed storage promoter that functions in the soybean plant operably linked to a polynucleotide encoding a soybean seed storage polypeptide having ?-ConGlycinin activity. The invention is further directed to a method of increasing seed protein content and/or increasing seed oil content of a soybean plant comprising transforming the soybean plant with a polynucleotide encoding a ?-ConGlycinin soybean seed storage promoter that functions in the soybean plant operably linked to a polynucleotide encoding a soybean seed storage polypeptide having ?-ConGlycinin activity.
    Type: Application
    Filed: October 28, 2022
    Publication date: May 18, 2023
    Applicant: Board of Trustees of Southern Illinois University
    Inventors: Khalid Meksem, Naoufal Lakhssassi
  • Patent number: 11571686
    Abstract: The present disclosure provides a method that embodies a simple and effective route to remove homogeneous catalysts from solutions wherein NMR/MRI signal amplification by reversible exchange (SABRE) or parahydrogen-induced polarization (PHIP) is performed. A method for recovering a homogeneous SABRE/PHIP catalyst for reuse is also described.
    Type: Grant
    Filed: February 17, 2020
    Date of Patent: February 7, 2023
    Assignees: Board of Trustees of Southern Illinois University, Vanderbilt University, The Regents of the University of California
    Inventors: Boyd M. Goodson, Eduard Y. Chekmenev, Igor V. Koptyug, Kirill V. Kovtunov, Roman V. Shchepin, Bryce E. Kidd, Jonathan Gesiorski, Max E. Gemeinhardt, Danila A. Barskiy
  • Publication number: 20230001400
    Abstract: The present disclosure provides a method that embodies a simple and effective route to remove homogeneous catalysts from solutions wherein NMR/MRI signal amplification by reversible exchange (SABRE) or parahydrogen-induced polarization (PHIP) is performed. A method for recovering a homogeneous SABRE/PHIP catalyst for reuse is also described.
    Type: Application
    Filed: February 17, 2020
    Publication date: January 5, 2023
    Applicants: Board of Trustees of Southern Illinois University, Vanderbilt University, The Regents of the University of California
    Inventors: Boyd M. Goodson, Eduard Y. Chekmenev, Igor V. Koptyug, Kirill V. Kovtunov, Roman V. Shchepin, Bryce E. Kidd, Jonathan Gesiorski, Max E. Gemeinhardt, Danila A. Barskiy
  • Patent number: 11533435
    Abstract: A multifunctional camera system having a bendable arm configured to be inserted into the thoracic cavity of a patient and camera head at a distal end of the bendable arm. The camera head has a high definition video camera and a light source. The camera head has a view adjustment mechanism for changing a view angle of the camera without changing the position of the camera head. A controller controls the view adjustment mechanism under command of a surgeon.
    Type: Grant
    Filed: April 5, 2019
    Date of Patent: December 20, 2022
    Assignee: Board of Trustees of Southern Illinois University
    Inventors: Traves Crabtree, Timothy York, Mitch McKay, Mingshao Zhang
  • Publication number: 20220380789
    Abstract: The present invention is directed to a transgenic soybean plant having increased oleic acid content comprising a polynucleotide comprising a fatty acid thioesterase (FAT) related promoter that functions in the soybean plant operably linked to a polynucleotide encoding a polypeptide having FAT activity. The invention is further directed to a method of increasing oleic acid content of a soybean plant comprising transforming a soybean plant with a polynucleotide comprising a fatty acid thioesterase (FAT) related promoter that functions in the soybean plant operably linked to a polynucleotide encoding a polypeptide having FAT activity.
    Type: Application
    Filed: May 27, 2022
    Publication date: December 1, 2022
    Applicant: Board of Trustees of Southern Illinois University
    Inventors: Khalid Meksem, Naoufal Lakhssassi, Dounya Knizia, Zhou Zhou
  • Publication number: 20220364106
    Abstract: The present invention is directed to a transgenic soybean plant with increased oleic acid content comprising a polynucleotide encoding a fatty acid desaturase (FAD) related promoter that functions in the soybean plant operably linked to a polynucleotide encoding a polypeptide having FAD activity. The invention is also related to a plant of an agronomically elite soybean variety with increased oleic acid content comprising a polynucleotide encoding a fatty acid desaturase (FAD) related promoter that functions in the soybean plant operably linked to a polynucleotide encoding a polypeptide having FAD activity. The invention is still further directed to a method of increasing the oleic acid content of a soybean plant comprising transforming the soybean plant with a polynucleotide encoding a fatty acid desaturase (FAD) related promoter that functions in the soybean plant operably linked to a polynucleotide encoding a polypeptide having FAD activity.
    Type: Application
    Filed: May 16, 2022
    Publication date: November 17, 2022
    Applicant: Board of Trustees of Southern Illinois University
    Inventors: Khalid Meksem, Naoufal Lakhssassi, Dounya Knizia
  • Patent number: 11480458
    Abstract: A pathogen transport modelled biomimetic sensor includes a stack of capacitive electrodes with a plurality of gaps therebetween. The gaps and electrodes are structured and arranged to model an outer layer and one or more sublayers of fresh food of interest. The electrodes are arranged to provide multiple measurable impedances that are affected in response to cell or polymeric biofilm presence that affects the electrostatic field around and between the electrodes and consequently changes the measurable impedances.
    Type: Grant
    Filed: March 19, 2020
    Date of Patent: October 25, 2022
    Assignee: Board of Trustees of Southern Illinois University
    Inventors: Mohammad Shavezipur, Minako Sumita, Roya Mazrouei
  • Patent number: 11437595
    Abstract: A light-harvesting material comprises a perovskite absorber doped with a metal chalcogenide. The light-harvesting material may be used in a photovoltaic device, comprising (1) a first conductive layer, (2) an optional blocking layer, on the first conductive layer, (3) a semiconductor layer, on the first conductive layer, (4) a light-harvesting material, on the semiconductor layer, (5) a hole transport material, on the light-harvesting material, and (6) a second conductive layer, on the hole transport material.
    Type: Grant
    Filed: July 10, 2019
    Date of Patent: September 6, 2022
    Assignee: Board of Trustees of Northers Illinois University
    Inventor: Tao Xu
  • Publication number: 20220158180
    Abstract: An anode of a battery comprises lithium metal, and a dopant, in the lithium metal. The anode has a thickness of at most 50 ?m, and the dopant is a metal with an electronegativity greater than lithium.
    Type: Application
    Filed: November 23, 2021
    Publication date: May 19, 2022
    Applicant: Board of Trustees of Northern Illinois University
    Inventors: Yingwen Cheng, Tao Xu, Ke Lu, Haiping Xu
  • Patent number: 11306305
    Abstract: The present disclosure provides CRISPR/Cas9 ribonucleoprotein compositions comprising chemically modified CRISPR RNA (crRNA) guide and trans-acting CRISPR RNA (tracrRNA) components. Methods of using the disclosed CRISPR/Cas9 ribonucleoprotein compositions are also provided.
    Type: Grant
    Filed: September 22, 2017
    Date of Patent: April 19, 2022
    Assignees: Board of Trustees of Southern Illinois University
    Inventors: Keith Gagnon, Masad Damha, Elise Malek-Adamian, Maryam Habibian, Daniel Timothy O'Reilly, Zachery Kartje
  • Patent number: 11232914
    Abstract: A photovoltaic device, comprises (1) a first conductive layer, (2) an optional blocking layer, on the first conductive layer, (3) a semiconductor layer, on the first conductive layer, (4) n light-harvesting material, on the semiconductor layer, (5) a hole transport material, on the light-harvesting material, and (6) a second conductive layer, on the hole transport material. The light harvesting material comprises, a pervoskite absorber, and the second conductive layer comprises nickel. The semiconductor layer tray comprise TiO2 nanowires. The light-harvesting material may comprise a pervoskite absorber containing a psuedohalogen.
    Type: Grant
    Filed: January 31, 2020
    Date of Patent: January 25, 2022
    Assignee: Board of Trustees of Northern Illinois University
    Inventor: Tao Xu
  • Publication number: 20220002274
    Abstract: The present disclosure describes novel compounds that are somatostatin receptor type 4 agonists.
    Type: Application
    Filed: September 3, 2021
    Publication date: January 6, 2022
    Applicant: Board of Trustees of the Southern Illinois University
    Inventors: Kenneth A. Witt, Albert M. Crider, William Neumann, Audrey Hospital, Karin Sandoval, Maria Kontoyianni
  • Patent number: 11217788
    Abstract: An anode of a battery comprises lithium metal, and a dopant, in the lithium metal. The anode has a thickness of at most 50 ?m, and the dopant is a metal with an electronegativity greater than lithium.
    Type: Grant
    Filed: April 16, 2019
    Date of Patent: January 4, 2022
    Assignee: Board of Trustees of Northern Illinois University
    Inventors: Yingwen Cheng, Tao Xu, Ke Lu, Haiping Xu
  • Patent number: 11156684
    Abstract: Provided are methods for nuclear spin polarization enhancement via signal amplification by reversible exchange at very low magnetic fields.
    Type: Grant
    Filed: October 28, 2015
    Date of Patent: October 26, 2021
    Assignees: Duke University, Vanderbilt University, Board of Trustees of Southern Illinois University
    Inventors: Warren S. Warren, Thomas Theis, Eduard Y. Chekmenev, Milton L. Truong, Aaron M. Coffey, Boyd Goodson, Fan Shi, Roman V. Shchepin
  • Patent number: 11136312
    Abstract: The present disclosure describes novel compounds that are somatostatin receptor type 4 agonists.
    Type: Grant
    Filed: May 11, 2018
    Date of Patent: October 5, 2021
    Assignee: Board of Trustees of the Southern Illinois University
    Inventors: Kenneth A. Witt, Albert M. Crider, William Neumann, Audrey Hospital, Karin Sandoval, Maria Kontoyianni
  • Patent number: 11116713
    Abstract: The present disclosure relates to compositions and methods for inhibiting the growth of, decreasing the amount of, and abolishing the growth of mutans streptococci.
    Type: Grant
    Filed: August 23, 2019
    Date of Patent: September 14, 2021
    Assignee: The Board of Trustees of Southern Illinois University
    Inventors: Kevin Rowland, Brian Hearring
  • Publication number: 20210252493
    Abstract: The present disclosure provides a method that embodies a simple and effective route to remove homogeneous catalysts from solutions wherein NMR/MRI signal amplification by reversible exchange (SABRE) or parahydrogen-induced polarization (PHIP) is performed. A method for recovering a homogeneous SABRE/PHIP catalyst for reuse is also described.
    Type: Application
    Filed: February 17, 2020
    Publication date: August 19, 2021
    Applicants: Board of Trustees of Southern Illinois University, Vanderbilt University, The Regents of the University of California
    Inventors: Boyd M. Goodson, Eduard Y. Chekmenev, Igor V. Koptyug, Kirill V. Kovtunov, Roman V. Shchepin, Bryce E. Kidd, Jonathan Gesiorski, Max E. Gemeinhardt, Danila A. Barskiy
  • Patent number: 11026793
    Abstract: Systems and methods for magnetic induction of a penile prosthesis are disclosed. The magnetic induction system includes a wand that has a coil arrangement covered with a thermal and electrical insulator sheath operable to generate an alternating magnetic field. The coil arrangement of the sheath is configured to receive the length of the penile prosthesis therein. The penile prosthesis may be made from a shape memory material such that application of alternating magnetic fields generated by the magnetic induction system induces eddy currents that raise the temperature of the penile prosthesis to a temperature above the austenitic transformation temperature that allows the penile prosthesis to achieve an erect state.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: June 8, 2021
    Assignee: The Board of Trustees of Southern Illinois University
    Inventors: Alberto Colombo, Kevin McVary, Brian Le
  • Patent number: 11016152
    Abstract: Provided are methods for nuclear spin polarization enhancement via signal amplification by reversible exchange at very low magnetic fields. The spin polarization is hyperpolarization of isotopically enriched heteronuclei by using a catalyst and parahydrogen to create a complex using iridium and applying magnetic fields in the microtesia range to transfer the spin order from parahydrogen to the complex.
    Type: Grant
    Filed: May 12, 2018
    Date of Patent: May 25, 2021
    Assignees: Vanderbilt University, Duke University, The Board of Trustees of Southern Illinois University
    Inventors: Eduard Y. Chekmenev, Danila A. Barskiy, Roman V. Shchepin, Warren S. Warren, Thomas Theis, Boyd Goodson
  • Patent number: 11000579
    Abstract: Provided herein are immunogenic compositions containing recombinant proteins capable of presenting all, or antigenic portions of, the Eimeria maxima, Eimeria tenella, and Eimeria acervulina IMP1 protein in developing active immunity to, and control of, coccidiosis. Also provided are methodologies of using the immunogenic compositions for administration to poultry and other animals in the control of coccidiosis. Nanoparticle-conjugated rIMP1 immunogenic compositions and methods of making and using them are provided.
    Type: Grant
    Filed: January 11, 2019
    Date of Patent: May 11, 2021
    Assignees: The United States of America, as represented by The Secretary of Agriculture, Board of Trustees of Souther Illinois University
    Inventors: Mark C. Jenkins, Vjollca Konjufca