Patents Assigned to Indiana University Foundation
  • Patent number: 4122163
    Abstract: New and more effective dentifrice preparations may be obtained by employing therein a cleaning and polishing constitutent comprising purified, calcined kaolin particles. Additionally, anticariogenic adjuvants such as sodium fluoride, NaF, may be incorporated in such dentifrice preparations.
    Type: Grant
    Filed: August 2, 1976
    Date of Patent: October 24, 1978
    Assignee: Indiana University Foundation
    Inventors: Joseph C. Muhler, Mark S. Putt
  • Patent number: 4121634
    Abstract: A device for opening glass-sealed vessels in order either to recover a gas from or to introduce a gas into a vacuum system or other confined atmosphere comprises first vessel receiving means adapted removably to receive therein a projecting end of the glass-sealed vessel along with second vessel receiving means similarly adapted removably to receive therein the projecting end of the glass-sealed vessel, with the proximal ends of the first and second vessel receiving means being positioned adjacent each other.
    Type: Grant
    Filed: August 29, 1977
    Date of Patent: October 24, 1978
    Assignee: Indiana University Foundation
    Inventors: John Michael Hayes, David John Des Marais
  • Patent number: 4117109
    Abstract: Dentifrice preparations exhibiting optimum cleaning ability and reduced abrasion may be obtained by employing therein low levels of a dental abrasive material (e.g., about 10-20% calcium pyrophosphate) in combination with an inert filler and one or more detergent agents. Additionally, increased therapeutic effectiveness may be achieved where anticariogenic adjuvants such as sodium fluoride, NaF, and stannous fluoride, SnF.sub.2, are incorporated in such dentifrice preparations.
    Type: Grant
    Filed: January 22, 1976
    Date of Patent: September 26, 1978
    Assignee: Indiana University Foundation
    Inventor: George K. Stookey
  • Patent number: 4108981
    Abstract: Improved anticariogenic oral compositions comprise a non-toxic and anticariogenically effective amount of one or more water-soluble alumium salts, a non-toxic stable complexing carboxylic acid or water-soluble salt thereof, and a carrier suitable for use in the oral cavity at a pH of about 7.0-9.0.
    Type: Grant
    Filed: August 2, 1976
    Date of Patent: August 22, 1978
    Assignee: Indiana University Foundation
    Inventors: Joseph C. Muhler, Mark S. Putt, Carl J. Kleber
  • Patent number: 4108979
    Abstract: Improved therapeutic dentifrice preparations comprise a nontoxic and anticariogenically effective amount of one or more water-soluble aluminum salts and a compatible dental abrasive selected from the group consisting of purified, calcined kaolin, calcined aluminum silicate, zirconium silicate, silica, alumina, calcined and uncalcined talcs, barium sulfate, resin abrasives, and mixtures thereof.
    Type: Grant
    Filed: August 2, 1976
    Date of Patent: August 22, 1978
    Assignee: Indiana University Foundation
    Inventors: Joseph C. Muhler, Mark S. Putt, Carl J. Kleber
  • Patent number: 4100918
    Abstract: This application discloses a dynamic knee extension assist device for paraplegic patients and others needing such a device. Cuffs adapted to be secured to a patient's thigh are provided along with mounting means adapted to be secured to a patient's leg below the knee. An elongated elastic member is provided with a means for removably mounting each end thereof to the cuff means at a predetermined tension. Also provided is means for pivotally securing the elastic means intermediate its ends to the mounting means. A lateral knee brace is rigidly disposed between the cuff and the mounting means. The elastic member provides a flexion moment when the patient is seated. As the patient arises, the flexion moment progressively diminishes and then converts to a progressively increasing extension moment as the patient continues to rise.
    Type: Grant
    Filed: March 25, 1977
    Date of Patent: July 18, 1978
    Assignee: Indiana University Foundation
    Inventor: John Glancy
  • Patent number: 4070247
    Abstract: Improved diagnostic media for isolating, identifying, and classifying Enterobacteriaceae comprise an effective amount of isopropyl-beta-D-thiogalactopyranoside in order to reduce the incidence of false lactose negative determinations and to differentiate between lac inducible and lac constitutive bacteria.
    Type: Grant
    Filed: March 30, 1977
    Date of Patent: January 24, 1978
    Assignee: Indiana University Foundation
    Inventor: Stanton C. Burt
  • Patent number: 4063035
    Abstract: A voiced-sound frequency analysis and display system displays two forms of spectral information about the signal: (1) the first and second formants as a point on an X-Y grid of a cathode ray tube, and (2) the full spectrum as a bar graph on an oscilloscope. Two sets of filters with associated circuitry perform the analysis. A scanning (peak hunting) second-formant selector circuit is also disclosed.
    Type: Grant
    Filed: November 12, 1976
    Date of Patent: December 13, 1977
    Assignee: Indiana University Foundation
    Inventors: Dudley Ralph Appelman, David Allen Link, Gerald Louret Stout
  • Patent number: 4043905
    Abstract: Selective monomolecular layers on siliceous surfaces used for the construction of high-resolution chromatographic columns are prepared by surface reactions with monohalogenated silanes, silazanes or silylamines, or monoalkoxy- or monoacetoxysilanes, and subsequent chemical modifications. Such monolayers form a basis for efficient films of chemically compatible stationary phases by introducing selective groups in gas-liquid chromatography and all forms of liquid chromatography, or for adsorbent modifications in gas-solid chromatography.
    Type: Grant
    Filed: August 26, 1974
    Date of Patent: August 23, 1977
    Assignee: Indiana University Foundation
    Inventors: Milos V Novotny, Karel Grohmann
  • Patent number: 4042680
    Abstract: Aqueous anionic maloaluminate complexes of the structure: ##STR1## at mildly alkaline pH are effective in reducing the incidence and severity of dental caries. These complexes may be advantageously incorporated in aqueous oral compositions, especially dentifrices, having pH values lying in the range of about 7.0 - 9.0.
    Type: Grant
    Filed: August 2, 1975
    Date of Patent: August 16, 1977
    Assignee: Indiana University Foundation
    Inventors: Joseph C. Muhler, Mark S. Putt, Carl J. Kleber, Clayton W. Yoho
  • Patent number: 4014095
    Abstract: An artificial tooth for use in a denture comprising a base portion, an occlusal portion, and an intermediate portion sandwiched between and secured to the base portion and occlusal portion, the intermediate portion being resilient to permit the occlusal portion yieldably to move relative to the base portion. The intermediate portion is disposed generally at equal vertical distances from the occlusal surface of the occlusal portion and the ridge lap surface of the base portion. Two connecting members, spaced apart in the mesial-distal direction, are provided for limiting the movement of the occlusal portion relative to the base position. Such members are rigidly connected to the occlusal portion and loosely pivotally connected to the base portion. The loose pivotal connection permits the occlusal portion to move from its normal portion toward the base portion even by tipping movement.
    Type: Grant
    Filed: October 8, 1975
    Date of Patent: March 29, 1977
    Assignee: Indiana University Foundation
    Inventor: Henry C. Heimansohn
  • Patent number: 3967321
    Abstract: The arm splint of an orthosis is attached to the forearm of a cervical 6 - cervical 7 motor lesion quadraplegic. The arm splint includes a thumb flange for holding the thumb of the patient, and a pivoting finger trough for holding the first and middle fingers of the patient. A Bowden cable is connected to the pivoting finger trough and is operated by a motor to cause the pivoting finger trough to pivot to close towards the thumb flange to provide finger prehension so that the patient can grasp objects. The motor is controlled by control circuitry that is operated by the patient touching a touch sensitive contact that is typically mounted on the arm rest of a wheelchair. The control means and the motor are powered by a twelve-volt car battery carried on the wheelchair. The control means also includes a time delay so that the patient can operate the control means by touching the touch sensitive contact and then move the arm and hand to a position ready for grasping.
    Type: Grant
    Filed: February 5, 1975
    Date of Patent: July 6, 1976
    Assignee: Indiana University Foundation
    Inventors: John Patrick Ryan, James Walter Cowan, Paul Kent Sharp, Marilyn Elaine Fess, James L. Babcock
  • Patent number: 3958334
    Abstract: An artificial tooth for use in a denture comprising a base portion, an occlusal portion, and an intermediate portion sandwiched between and secured to the base portion and occlusal portion, the intermediate portion being resilient to permit the occlusal portion yieldably to move relative to the base portion. The intermediate portion is disposed generally at equal vertical distances from the occlusal surface of the occlusal portion and the ridge lap surface of the base portion. An anchor wire or wires or other connecting members are provided for limiting the movement of the occlusal portion relative to the base portion. Such an anchor wire may preferably be rigidly connected to the occlusal portion and loosely pivotally connected to the base portion with the anchor wire extending downwardly through the sandwiched intermediate portion. The loose pivotal connection permits the occlusal portion to move from its normal position toward the base portion even by tipping movement.
    Type: Grant
    Filed: December 13, 1974
    Date of Patent: May 25, 1976
    Assignee: Indiana University Foundation
    Inventor: Henry C. Heimansohn
  • Patent number: 3958333
    Abstract: Artificial teeth for use in a denture comprising a denture base and a plurality of teeth anchored in the denture base, each tooth having a base portion providing a ridge lap surface and an occlusal portion providing an occlusal surface, wherein the improvement comprises one or more lugs extending outwardly from each tooth intermediate its occlusal surface and the ridge lap surface to serve as a locating lug or tab for positioning the tooth in the mold in which the denture base is formed on the base portions of the teeth. These locating lugs or tabs or at least those which are not embedded in the denture base are removed by grinding and polishing.
    Type: Grant
    Filed: March 6, 1975
    Date of Patent: May 25, 1976
    Assignee: Indiana University Foundation
    Inventor: Henry C. Heimansohn
  • Patent number: 3947592
    Abstract: Addiction to opiate drugs, e.g., heroin, is treated by administering a beta-adrenergic-receptor-blocking drug, e.g. propranolol, which is found to block the rewarding and euphoric effects of the narcotic and to prevent the recurrence of hunger for the narcotic after withdrawal with methadone.
    Type: Grant
    Filed: May 22, 1972
    Date of Patent: March 30, 1976
    Assignee: Indiana University Foundation
    Inventor: Hanus J. Grosz