Patents Assigned to Institut National de la Recherche Agronomique
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Patent number: 11834468Abstract: The present invention provides protected tetrasaccharides, their process of preparation and their use in the synthesis of oligosaccharides, in particular fragments of O-antigens from Shigella flexneri, for example of serotype 1a, 1b, 2a, 2b, 3a, X, 4a, 4b, 5a, 5b, 7a or 7b.Type: GrantFiled: July 3, 2018Date of Patent: December 5, 2023Assignees: INSTITUT PASTEUR, INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Laurence Mulard, Guillaume Le Heiget, Zhaohu Hu, Louis-Antoine Barel, Isabelle Andre, Claire Moulis, Magali Remaud-Simeon, Sophie Barbe, Mounir Benkoulouche, Akli Ben Imeddourene
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Patent number: 11717543Abstract: The present invention relates to a bacterial strain of the Faecalibacterium prausnitzii species selected from a bacterial strain belonging to one of the phylogroups I, II and III, for use in the treatment and/or prevention of visceral abdominal pain in an individual. The present invention also concerns compositions comprising said bacterial strains as well as specific strains as such.Type: GrantFiled: June 22, 2020Date of Patent: August 8, 2023Assignees: INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA), INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS, ECOLE D'INGENIEURS DE PURPANInventors: Philippe Langella, Sylvie Miquel, Rebeca Martin Rosique, Luis Bermudez Humaran, Muriel Thomas, Harry Sokol, Frédéric Carvalho, Vassilia Theodorou
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Patent number: 11678679Abstract: A meat analogue may include a macrostructure of connected sheared fibers oriented parallel to one another and gaps positioned between the sheared fibers. The macrostructure may include meat and may include a vegetable protein. An extrusion system may include an extruder and a die. The extrusion system may produce a meat analogue. A meat analogue may include an animal protein. The extruder may be connectable to the die. The extrusion system may be configured to direct a material including an animal protein from the extruder to the die and through a fluid path extending through the die. The die may be configured to inject a fat or a fat analogue into the material such that the fat or the fat analogue is embedded but visually distinct from the material including the animal protein when the fat or the fat analogue and the material exit the die.Type: GrantFiled: April 8, 2020Date of Patent: June 20, 2023Assignees: SOCIÉTÉ DES PRODUITS NESTLÉ S.A., UNIVERSITE DE MONTPELLIER, INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUEInventors: Patrick Pibarot, Christophe Joseph Etienne Schmitt, Christian Sanchez, Marie-Héléne Morel
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Patent number: 11666599Abstract: The present invention relates to a novel pharmaceutical use of bromide, i.e. the treatment of autism spectral disorder (ASD).Type: GrantFiled: November 28, 2017Date of Patent: June 6, 2023Assignees: INSERM, INTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, INRA, INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE, CNRS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE STRASBOURGInventors: Sébastien Roux, Thierry Plouvier, Julie Le Merrer, Jérôme Becker
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Patent number: 11635372Abstract: A process for detecting the sensitivity of one or more polymers and/or of one or more mixtures of polymers to a compound, including the steps of exposing a plurality of individualized micro-deposits including the polymer(s) and/or the mixture(s) of polymers to the compound, and detecting, by interferometry, a variation in appearance of an assembly of micro-deposits exposed to the compound and/or a variation in the dimensions and/or refractive index of at least one of the micro-deposits exposed to the compound, linked to an interaction between the polymer(s) and/or the mixture(s) of polymers and the compound.Type: GrantFiled: June 1, 2018Date of Patent: April 25, 2023Assignees: Universite De Lille, Centre National De La Recherche Scientifique, Institut National De La Recherche Agronomique, Institute National Des Sciences Appliquees De ToulouseInventors: Vincent Senez, Alexis Vlandas, Sebastien Lamant, Bernard Cathala, Celine Moreau, Gabrielle Veronese, Sophie Bozonnet, Elisabeth Laville, Megane Cleret
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Patent number: 11596657Abstract: The present invention relates to the preventive or curative treatment of metabolic syndrome and the associated disorders with AhR agonist or microorganism producing AhR agonist.Type: GrantFiled: July 11, 2017Date of Patent: March 7, 2023Assignees: INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE, SORBONNE UNIVERSITÉ, ASSISTANCE PUBLIQUE—HÔPITAUX DE PARIS, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALEInventors: Harry Sokol, Jane Mea Natividad, Bruno Lamas, Henri Duboc, Mathias Lavie-Richard, Marie-Laure Michel, Philippe Langella
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Patent number: 11498942Abstract: The present invention is directed to an isolated synthetic tripeptide of formula H-D-Phe-N-Methyl-L-Val-L-Ala-OMe (SEQ ID NO:1), or a derivative thereof, and to the corresponding lipotripeptides, which are specific to Mycobacterium avium subsp. paratuberculosis (Map) S-type strain, as well as derivatives and conjugates thereof. The invention also concerns the use of these antigens in different methods and tests for detecting Map infection, especially by detecting humoral response and cell mediated response of infected animals. The invention is also directed to a genetic signature of Map and a mass spectrometry and NMR spectroscopy signature of Map presence or infection.Type: GrantFiled: December 20, 2017Date of Patent: November 15, 2022Assignees: INSTITUT PASTEUR, INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA), THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTUREInventors: John P. Bannantine, Gilles Etienne, Sylvie Bay, Franck Biet
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Patent number: 11484569Abstract: The invention concerns a Reg3? polypeptide (also known as Hepatocarcinoma-Intestine-Pancreas/Pancreatitis Associated Protein (HIP/PAP)) for use in the protection of oxygen sensitive gram-positive bacteria, compositions comprising the polypeptide and their use. The inventors have shown that an increase in the concentration of the h Reg3? lectin into the gastrointestinal tract (GIT) lumen of hReg3?-transgenic mice induced significant changes in the composition of the gut microbiota, and dramatically improved host resistance to intestinal inflammation. hReg3? exerted a potent antioxidant activity on intestinal epithelial cells during colitis, and in particular the ROS scavenging activity, in particular, by promoting the survival of highly oxygen sensitive bacteria. Inventors also showed that h Reg3?-transgenic mice resist better to DSS-induced colitis after antibiotherapy.Type: GrantFiled: July 13, 2018Date of Patent: November 1, 2022Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS, INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA), UNIVERSITÉ PARIS-SUDInventors: Joël Dore, Jamila Faivre, Nicolas Moniaux, Christian Brechot, Marion Darnaud
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Patent number: 11453886Abstract: The present invention relates to GFLV virus-like particles and the uses thereof in various fields, such as the pharmaceutical, agro, or veterinary areas.Type: GrantFiled: March 13, 2018Date of Patent: September 27, 2022Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE STRASBOURG, INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE, INSTITUT FRANCAIS DE LA VIGNE ET DU VIN, VRIJE UNIVERSTEIT BRUSSELInventors: Serge Muyldermans, Gérard Demangeat, Ahmed Ghannam, Léa Ackerer, Caroline Hemmer, Christophe Ritzenthaler, Vianney Poignavent
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Publication number: 20220295840Abstract: A modulated protein composition is described with improved flavor properties over a vegetable protein. Methods of making a modulated protein composition including the use of a volatile modulating yeast culture to ferment a vegetable protein to produce the modulated protein composition are described. Also disclosed are a fermented vegetable composition made from a modulated protein composition, and ingredients and foods including a fermented vegetable composition or a modulated protein composition.Type: ApplicationFiled: July 31, 2019Publication date: September 22, 2022Applicants: SODIMA, INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA), INSTITUT DES SCIENCES ET INDUSTRIES DU VIVANT ET DE L'ENVIRONNEMENTInventors: Sébastien Fraud, Cynthia El Youssef, Pascal Bonnarme, Sophie Landaud-Liautaud, Sandra Helinck
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Patent number: 11445671Abstract: The present invention concerns an isolated polynucleotide responsible of haploid induction in maize plants and related processes. Additionally, the invention relates to plants that have been genetically transformed with the polynucleotide of the invention. The invention also relates to a process for screening a mutant plant population for enhanced haploid induction by using said isolated polynucleotide. The invention further relates to molecular markers associated with haploid induction in maize plants and their use in quality control for inducer lines.Type: GrantFiled: May 6, 2016Date of Patent: September 20, 2022Assignees: INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA), LIMAGRAIN EUROPE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Jean-Pierre Martinant, Jordi Comadran, Jean-Baptiste Laffaire, Peter Rogowsky, Thomas Widiez
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Publication number: 20220282186Abstract: A method for removing a biofilm present on a substrate includes providing a detergent component comprising a sequestrant, a wetting agent and a dispersant, and an enzymatic component containing at least one protease, and at least one polysaccharidase in solution in an aqueous phase in sequence or simultaneously, and applying the solution to the substrate for a predetermined period of time to effect biofilm removal from the substrate.Type: ApplicationFiled: May 17, 2022Publication date: September 8, 2022Applicants: S.A. REALCO, INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUEInventors: Gauthier Boels, Gordon Blackman, Christine Faille, Yannick Lequette, Martine Clarisse
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Patent number: 11365374Abstract: Composition for the removal of biofilms present on a substrate, characterized in that it comprises at least one detergent component comprising a sequestrant and also a wetting agent and a dispersant and at least one enzymatic component containing at least one protease, at least one laccase and at least one polysaccharidase, method of implementation thereof and uses thereof.Type: GrantFiled: July 24, 2018Date of Patent: June 21, 2022Assignees: S.A. REALCO, INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUEInventors: Gauthier Boels, Gordon Blackman, Christine Faille, Yannick Lequette, Martine Clarisse
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Patent number: 11341594Abstract: Apparatus to acquire an image of roots of a plant located in a target rhizotron. The apparatus includes: a turntable having a rotation axis and intended to support the target rhizotron; a lightening device; a first camera having an optical axis substantially oriented toward the rotation axis; a focus sensor arranged so as to provide a measure at least one parameter of the first camera; a control module, configured to receive the measure, compare the measure to comparison data, and inform an operator accordingly, the comparison data comprising data related to reference rhizotrons different than the target rhizotron, and/or data related to one or several previously acquired images of the target rhizotron.Type: GrantFiled: May 29, 2018Date of Patent: May 24, 2022Assignees: INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA), INOVIAFLOWInventors: Christophe Salon, Christian Jeudy, Christophe Baussart, Fédéric Chazallet, Mickael Lamboeuf, Julien Martinet
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Patent number: 11274122Abstract: The invention relates to a method for separating, from a culture medium, an enzymatic cocktail and the fungus Trichoderma Reesei, the culture medium resulting from enzyme production by the fungus, method in which: said culture medium is subjected, in a period of no longer than 30 h from the halting of production, to a separation on a filter press lined with a fabric having a porosity of 3-20 ?m, so as to obtain a filtrate having a corrected optical density OD at 600 nm of less than 2.5; and the liquid phase obtained is subjected to tangenital micro-filtration on a ceramic membrane having a cut-off limit of 0.5 to 1.4 ?m, so that the corrected OD at 600 nm does not exceed 0.1.Type: GrantFiled: July 11, 2017Date of Patent: March 15, 2022Assignees: IFP Energies Nouvelles, Institut National De La Recherche AgronomiqueInventors: Mohamed Fadhel Ben Chaabane, Romain Rousset
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Publication number: 20220064076Abstract: The present invention relates to the field of crop fertilization, and particularly to a biofertilizing bacterial strain. In particular, the present invention relates to the bacterial strain deposited on Oct. 24, 2018, at the Collection Nationale de Culture de Microorganismes (CNCM), 28 rue du Dr. Roux, 75724 PARIS CEDEX 15, under the Budapest Treaty under number CNCM I-5372, and to the uses of this strain. The invention also relates to a composition comprising the above-mentioned bacterial strain and to a fertilization process comprising the application of this composition to a plant or to a soil.Type: ApplicationFiled: December 19, 2019Publication date: March 3, 2022Applicants: Université de Lorraine, Institut National de la Recherche AgronomiqueInventors: Sophie SLEZACK - DESCHAUMES, Séverine PIUTTI, Pierre L'YVONNET, Sandro ROSELLI
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Publication number: 20220055960Abstract: The present invention relates to the field of crop fertilization, and particularly to a biofertilizing bacterial strain. In particular, the present invention relates to the bacterial strain deposited on Oct. 24, 2018, at the Collection Nationale de Culture de Microorganismes (CNCM), 28 rue du Dr. Roux, 75724 PARIS CEDEX 15, under the Budapest Treaty under number CNCM I-5373, and to the uses of this strain. The invention also relates to a composition comprising the above-mentioned bacterial strain and to a fertilization process comprising the application of this composition to a plant or to a soil.Type: ApplicationFiled: December 19, 2019Publication date: February 24, 2022Applicants: Université de Lorraine, Institut National de la Recherche AgronomiqueInventors: Sophie SLEZACK - DESCHAUMES, Séverine PIUTTI, Pierre L'YVONNET, Sandro ROSELLI
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Patent number: 11236403Abstract: The invention concerns a continuous method for treating a lignocellulosic biomass before enzymatic hydrolysis, said method comprising a transfer of crushed then pressed biomass to a step of impregnation by an acid liquor, the impregnated biomass dripping over the area containing the impregnation liquor, then the resulting wet biomass is pressed and sent to a steam explosion step. The impregnation liquor is prepared in a dedicated area from the used liquor from the dripping operation and/or that from the pressing operation, prior to the explosion step. The invention also concerns the facility for implementing the method.Type: GrantFiled: July 11, 2017Date of Patent: February 1, 2022Assignees: INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE, IFP Energies nouvelles, AGRO INDUSTRIES RECHERCHE ET DEVELOPPEMENTInventors: Damien Hudebine, Romain Rousset, Olivier Carnnot
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Patent number: 11166991Abstract: The invention relates to a novel bacterial strain deposited with the CNCM under number 1-4969. This strain has properties that are useful in the treatment of respiratory disorders. The invention also relates to compositions and uses of said strain.Type: GrantFiled: January 27, 2017Date of Patent: November 9, 2021Assignee: Institut National De La Recherche AgronomiqueInventors: Muriel Thomas, Aude Remot-Brizion, Philippe Langella
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Patent number: 11103564Abstract: The present invention relates to a composition exhibiting a bile-salt hydrolase activity for its use for the treatment or the prevention of giardiasis, said composition comprising a bile-salt hydrolase (BSH)enzyme, a bacterium able to secrete a BSH, a recombinant host cell able to secrete a BSH, or a combination thereof. The present invention also relates to the use of a composition exhibiting a BSH activity for the treatment or the prevention of giardiasis, and to a pharmaceutical composition or a food composition comprising, as an active principle, a BSH, a lactic acid bacterium able to secrete a BSH, or a recombinant host cell able to secrete a BSH.Type: GrantFiled: June 19, 2019Date of Patent: August 31, 2021Assignees: INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE, MUSEUM NATIONAL D'HISTOIRE NATURELLE, ECOLE NATIONALE VETERINAIRE D'ALFORTInventors: Luis G. Bermudez-Humaran, Thibault Allain, Isabelle Florent, Philippe Langella, Philippe Grellier, Marie-Agnes Travers, Bruno Polack