Patents Assigned to Institut National de la Recherche Agronomique (Inra)
  • Patent number: 6824797
    Abstract: This invention relates to a method for extracting, fractionating and purifying polyphenolic compounds originating from plants, wherein the purification is performed by adsorption on an adsorbing styrene-divinyl benzene resin, followed by the elution of the polyphenolic compounds.
    Type: Grant
    Filed: February 15, 2002
    Date of Patent: November 30, 2004
    Assignees: Institut National de la Recherche Agronomique INRA, SCALIME France
    Inventors: Pascale Goupy, Marie-Josephe Amiot-Carlin, Jean-Louis Escudier, Michel Mikolajczak, Michel Martin
  • Patent number: 6800754
    Abstract: A method for directly producing a mixture of cellulose sulfoacetate derivatives by esterification of cellulosic material, characterized in that it comprises the following steps i) the cellulosic material is suspended in a glacial acetic acid solution and the excess acetic acid is eliminated ii) the cellulosic acid that is swollen with acetic acid is suspended in a sulfuric acid solution in glacial acetic acid and iii) the cellulose material is made to react by adding acetic anhydride.
    Type: Grant
    Filed: March 4, 2002
    Date of Patent: October 5, 2004
    Assignee: Institut National de la Recherche Agronomique (INRA)
    Inventors: Gaelle Chauvelon, Luc Saulnier, Alain Buleon, Jean-Francois Thibault
  • Patent number: 6616939
    Abstract: The invention concerns a rehydration fluid composition, useful in particular for feeding young animals no longer able to digest milk, comprising lactose or glucose or a product based on lactose or glucose: a mineral supplement ensuring restoration of digestive losses. The invention is characterised in that the composition further comprises an efficient quantity of soluble vegetable proteins and vegetable lipids ensuring suitable appropriate energy intake.
    Type: Grant
    Filed: May 4, 2001
    Date of Patent: September 9, 2003
    Assignee: Institut National de la Recherche Agronomique (INRA)
    Inventors: Christian Remesy, Christian Demigne
  • Patent number: 6586025
    Abstract: Process for enhancing the flavour of a cheese or of a cheese-flavoured food product whose preparation comprises a maturation step in the presence of lactic acid bacteria, characterized in that a preparation additive comprising at least one keto acid chosen from the group consisting of &agr;-ketoglutaric acid, &agr;-ketoisocaproic acid ketoisovaleric acid and phenylpyruvic acid is used to increase the catabolism of the amino acids in the cheese or food product by the said bacteria.
    Type: Grant
    Filed: January 20, 2000
    Date of Patent: July 1, 2003
    Assignee: Institut National de la Recherche Agronomique (INRA)
    Inventors: Mireille Yvon, Jean-Claude Gripon
  • Patent number: 6582951
    Abstract: The invention concerns the integration of a gene of interest into the genome of a Yarrowia strain devoid of zeta sequences, by transforming said strain using a vector bearing zeta sequences.
    Type: Grant
    Filed: April 27, 2001
    Date of Patent: June 24, 2003
    Assignees: Institut National de la Recherche Agronomique - INRA, Centre National de la Recherche Scientifique - CNRS
    Inventors: Jean-Marc Nicaud, Claude Gaillardin, Georges Pignede
  • Publication number: 20030040049
    Abstract: A mutant lactic bacteria with a capacity for overexpressing one or more peptidases, wherein gene codY is inactivated.
    Type: Application
    Filed: April 15, 2002
    Publication date: February 27, 2003
    Applicant: Institut National de la Recherche Agronomique-INRA
    Inventors: Eric Guedon, Jamila Anba-Mondoloni, Christine Delorme, Pierre Renault
  • Publication number: 20020187207
    Abstract: This invention relates to a method for extracting, fractionating and purifying polyphenolic compounds originating from plants, wherein the purification is performed by adsorption on an adsorbing styrene-divinyl benzene resin, followed by the elution of the polyphenolic compounds.
    Type: Application
    Filed: February 15, 2002
    Publication date: December 12, 2002
    Applicant: INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE INRA
    Inventors: Pascale Goupy, Marie-Josephe Amiot-Carlin, Jean-Louis Escudier, Michel Mikolajczak, Michel Martin
  • Publication number: 20020142322
    Abstract: The invention relates to a method for evaluating muscular proteolysis. The invention is essentially characterized in that it consists in determinining the Cathepsin L content and/or mRNA content thereof in a muscular sample or blood sample from the human or animal body and includes a muscular proteolysis evaluation agent in order to carry out said method.
    Type: Application
    Filed: August 30, 2001
    Publication date: October 3, 2002
    Applicant: Institut National de la Recherche Agronomique: INRA
    Inventors: Marc Ferrara, Christiane Deval, Daniel Bechet
  • Patent number: 6169172
    Abstract: The use of a prolactin receptor intracytoplasmic domain or a growth hormone receptor intracytoplasmic domain, or of a fragment of either one of said domains, for achieving the secretion of a protein of interest produced in a eukaryotic host cell, is disclosed.
    Type: Grant
    Filed: March 16, 1998
    Date of Patent: January 2, 2001
    Assignees: Institut National de la Recherche Agronomique (Inra), Centre National de la Recherche Scientifique (Cnrs)
    Inventors: G{acute over (e)}rard Devauchelle, Laurence Garnier, Claire Cahoreau, Martine Cerutti
  • Patent number: 6096321
    Abstract: A CS31A protein capsule subunit having an aminoacid sequence modified by at least one heterologous peptide, the CS31A protein capsule comprising said subunit, and micro-organisms having the CS31A protein capsule with its subunit aminoacid sequence modified by at least one heterologous peptide, are disclosed. Methods for preparing said subunits, CS31A protein capsules comprising same, and micro-organisms having CS31A protein capsules, as well as the use thereof for preparing vaccines, producing peptides and preparing immunoassays, are also disclosed.
    Type: Grant
    Filed: February 16, 1996
    Date of Patent: August 1, 2000
    Assignee: Institut National de la Recherche Agronomique-INRA
    Inventors: Jean-Pierre Girardeau, Christine Martin, Marie-Claire Mechin, Maurice Der Vartanian, Fran.cedilla.ois Bousquet
  • Patent number: 5717070
    Abstract: The present invention is directed to a family of phospholipid binding and transporting proteins, a method for preparing same from fungi, and their use in cosmeticology, the agri-foodstuffs industry and pharmacology Phospholipid proteins are capable of binding, transporting and/or rearranging lipids between membranes, optionally in combination with active principles. Furthermore, the phospholipid proteins are hydrophobic and acidic, have a molecular weight of under 50 kDa, and may be prepared from a non-toxic filamentous fungus capable of developing on a lipid-enriched medium, particularly from raw extracts of fungi.
    Type: Grant
    Filed: January 23, 1995
    Date of Patent: February 10, 1998
    Assignee: Institut National de la Recherche Agronomique-Inra
    Inventors: Eric Record, Laurence Lesage, Didier Marion, Bernard Cahagnier, Daniel Richard-Molard, Marcel Asther
  • Patent number: 5565333
    Abstract: A DNA sequence derived by the mutation from a ColE1-type replication origin is provided, wherein the sequence is characterized in that it includes at least one of the following mutations, which are defined in relation to the wild ColE1 origin: a Guanine to Adenine transversion in position 2976; and a Guanine deletion in position 3057. This sequence increases the number of copies of the plasmids which include it. Plasmids containing the replication origin, and their uses in the amplification of DNA sequences and the production of polypeptides by genetic engineering, are also disclosed.
    Type: Grant
    Filed: May 16, 1994
    Date of Patent: October 15, 1996
    Assignees: Institut National de la Recherche Agronomique (INRA), Centre National de la Recherche Scientifique (CNRS)
    Inventors: Gerard Devauchelle, Laurence Garnier, Martine Cerutti, Viviane Valverde, Jean-Michel Masson
  • Patent number: 5338675
    Abstract: A novel toxin of the genus Hirsutella which is useful in controlling invertebrate pests.
    Type: Grant
    Filed: June 23, 1992
    Date of Patent: August 16, 1994
    Assignees: University of Florida, l'Institut National de la Recherche Agronomique (INRA), Le Centre National de la Recherche Scientifique (CNRS)
    Inventors: Clayton W. McCoy, Alain J. Vey, Isabelle M. Mazet
  • Patent number: 5328827
    Abstract: Synthetic oligonucleotides of 17 or more consecutive nucleotides of the 49 bases of formula (A) to be used as molecular probes for sexing the embryos or foetuses of ruminant mammals or as molecular probes for detecting a Y chromosome in a spermatozoid population of ruminant mammals of the Bos genus and their use in process of amplification and hybridization assays.
    Type: Grant
    Filed: December 28, 1992
    Date of Patent: July 12, 1994
    Assignees: Institut National de la Recherche Agronomique - INRA, Institut Pasteur, Commissariat a l'Energie Atomique
    Inventors: Colin Bishop, Corinne Cotinot, Marc Fellous, Marek Kirszenbaum, Marcel Vaiman
  • Patent number: 5212087
    Abstract: The present invention relates to ars sequences which are efficacious in Yarrowia lipolytica, as well as to plasmids carrying these sequences.The strains of Y. lipolytica transformed with the said plasmids may be used in fermentation processes enabling proteins of industrial importance to be prepared.
    Type: Grant
    Filed: January 27, 1989
    Date of Patent: May 18, 1993
    Assignee: Institut National de la Recherche Agronomique (INRA)
    Inventors: Phillippe Fournier, Claude Gaillardin, Bernard Kudla, Henri Heslot
  • Patent number: 5154748
    Abstract: These compounds, represented by the formula (I) below, are used by way of agents inducing resistance to cryptogamic diseases in plants capable of being infested by a pathogenic fungus, for example, for the protection of wheat especially with respect to Septoria nodorum, Erysiphe graminis and Gaemannomyces graminis; of capsicum with respect to Phytophthora capsici; of melon with respect to Pseudoperonospora cubensis; of tomato with respect to Phytophthora infestans; and of "Xanthi" tobacco with respect to Phytophthora parasitica var. nicotianae.
    Type: Grant
    Filed: February 23, 1990
    Date of Patent: October 13, 1992
    Assignees: Institut National de la Recherche Agronomique (INRA), Centre National de la Recherche Scientifique (CNRS)
    Inventors: Maud Bruneteau, Paul-Michel Molot, Thadee Staron, Olivier Lhomme, Pierre Mas
  • Patent number: 5099009
    Abstract: Plant wall-rich products originating, for example, from higher plants naturally rich in pectins, algae, or from by-products, such as wheat bran, potato pulp, shells or oil works residues, and the like, are modified to contain a fraction of water-soluble polysaccharides which is higher than, in particular equal to at least twice that existing naturally, without modification of their overall chemical composition. To obtain them, water is added, if necessary to the natural product in the divided state, to form a mixture capable of undergoing a shearing treatment, and the resulting product is subjected to a shearing force before extrusion, resulting in modified products as aggregates which can be converted into powder. By means of aqueous extraction, performed directly on the extruded product, a water-soluble fraction is obtained, from which there are isolated, for example, pectins, with a degree of methylation .gtoreq.
    Type: Grant
    Filed: September 1, 1989
    Date of Patent: March 24, 1992
    Assignee: Institut National de la Recherche Agronomique (INRA)
    Inventors: Jean-Francois Thibault, Guy Della Valle, Marie-Christine Ralet
  • Patent number: 4981618
    Abstract: These compounds, represented by the formula (I) below, are used by way of agents inducing resistance to cryptogamic diseases in plants capable of being infested by a pathogenic fungus, for example, for the protection of wheat especially with respect to Septoria nodorum, Erysiphe graminis and Gaemannomyces graminis; of capsicum with respect to Phytophthora capsici; of melon with respect to Pseudoperonospora cubensis; of tomato with respect to Phytophthora infestans; and of "Xanthi" tobacco with respect to Phytophthora parasitica var. nicotianae. ##STR1## in which Z denotes the residues ##STR2## with 0.ltoreq.n1.ltoreq.15; 0.ltoreq.m1.ltoreq.15 and n1+m1=15; and CH.sub.3 --(CH.sub.2).sub.n2 --CH--(CH.sub.2).sub.m2 --, with 0.ltoreq.n2.ltoreq.18; 0.ltoreq.m2.ltoreq.18, and n2+m2=18.
    Type: Grant
    Filed: February 24, 1989
    Date of Patent: January 1, 1991
    Assignees: Institut National de la Recherche Agronomique (INRA), Centre National de la Recherche Scientifique
    Inventors: Maud Bruneteau, Paul-Michel Molot, Thadee Staron, Olivier Lhomme, Pierre Mas
  • Patent number: 4957865
    Abstract: The invention relates to a virus for cloning or expression of a foreign gene, characterized in that it consists of all or part of the genome of avian erythroblastosis virus and contains at least one foreign gene situated between the 3 LTR sequences.
    Type: Grant
    Filed: June 4, 1986
    Date of Patent: September 18, 1990
    Assignee: Institut National de la Recherche Agronomique (INRA)
    Inventors: Jacques Samarut, Gerard Verdier, Miloud Benchaibi, Pierre Savatier, Didier Poncet, Frederic Flamant, Jiao-Hao Xiao, Pierrick Thoraval, Frederique Chambonnet, Victor Nigon
  • Patent number: 4652454
    Abstract: The present invention relates to a rehydrating composition and a complement for its preparation.The rehydrating composition comprises:lactose or a lactose-based product; anda complement containing chloride, acetate and or propionate anions and sodium, potassium and/or magnesium cations.The composition is applied especially to the feeding of young ruminants and piglets which can no longer digest milk normally.
    Type: Grant
    Filed: January 11, 1984
    Date of Patent: March 24, 1987
    Assignee: Institut National de la Recherche Agronomique (INRA)
    Inventors: Christian Remesy, Christian Demigne