Patents Assigned to Institut National des Sciences
  • Publication number: 20180264145
    Abstract: The invention relates to novel biocompatible hybrid nanoparticles of very small size, useful in particular for diagnostics and/or therapy. The purpose of the invention is to offer novel nanoparticles which are useful in particular as contrast agents in imaging (e.g. MRI) and/or in other diagnostic techniques and/or as therapeutic agents, which give better performance than the known nanoparticles of the same type and which combine both a small size (for example less than 20 nm) and a high loading with metals (e.g. rare earths), in particular so as to have, in imaging (e.g. MRI), strong intensification and a correct response (increased relaxivity) at high frequencies.
    Type: Application
    Filed: May 23, 2018
    Publication date: September 20, 2018
    Applicants: NANOH, UNIVERSITE LYON 1 CLAUDE BERNARD, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON
    Inventors: François LUX, Olivier TILLEMENT, Maxime SAINT JEAN, Pierre MOWAT, Pascal PERRIAT, Stéphane ROUX, Anna MIGNOT
  • Patent number: 10066234
    Abstract: The invention relates to yeast cells modified to express a functional type I RuBisCO enzyme, and a class II phosphoribulokinase. The expression of these enzymes recreates a Calvin cycle in said yeasts in order to enable the yeasts to use carbon dioxide.
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: September 4, 2018
    Assignees: Institut National de la Recherche Agronomique, Institut National Des Sciences Appliquees De Toulouse, Centre National de la Recherche Scientifique
    Inventors: Denis Pompon, Frederic Paques, Julie Lesage, Stephane Guillouet, Florence Bonnot, Jillian Marc, Nathalie Gorret, Carine Bideaux, Christel Boutonnet
  • Patent number: 10062145
    Abstract: The invention relates to a method for mapping the crystal orientations of a polycrystalline material, the method comprising: receiving (21) a series of images of the polycrystalline material, which images are acquired by an acquiring device in respective irradiation geometries; estimating (22) at least one intensity profile for at least one point of the material from the series of images, each intensity profile representing the intensity associated with the point in question as a function of irradiation geometry; and determining (24) a crystal orientation for each point in question of the material by comparing (23) the intensity profile associated with said point in question to theoretical signatures of intensity profiles of known crystal orientations, which signatures are contained in a database.
    Type: Grant
    Filed: January 23, 2015
    Date of Patent: August 28, 2018
    Assignees: INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE CLAUDE BERNARD LYON 1
    Inventor: Cyril Langlois
  • Publication number: 20180216138
    Abstract: The present invention relates to a novel polypeptide having the enzymatic activity of reduction of NADP+ using electrons from reduced ferredoxin (Ferredoxin-NADP+ reductase activity), a polynucleotide having a nucleotide sequence encoding such polypeptide and uses thereof. The invention relates to the modulation of the Ferredoxin NADP+ reductase activity in a microorganism by varying the expression level of the polynucleotide coding for such polypeptide. The invention also relates to the production of commodity chemicals, especially ethanol, n-butanol, 1,3-propanediol, 1,2-propanediol, isopropanol and acetone by fermenting microorganisms wherein their Ferredoxin NADP+ reductase activity is modulated.
    Type: Application
    Filed: July 22, 2016
    Publication date: August 2, 2018
    Applicants: Institut National des Sciences Appliquees, Centre National de la Recherche Scientifique (CNRS), Institut National de la Recherche Agronomique
    Inventors: Philippe Soucaille, Isabelle Meynial-Salles, Céline Foulquier, Antoine Riviere
  • Patent number: 10017748
    Abstract: The present invention relates to a recombinant process for the production of truncated or mutated dextransucrases while conserving the enzymatic activity or their specificity in the synthesis of the ?-1,6 bonds. The present invention relates to nucleic acid sequences of truncated or mutated dextransucrases, vectors containing the nucleic acid sequences and host cells transformed by sequences encoding truncated or mutated dextransucrases. In another aspect, the invention concerns a method for producing, in a recombinant manner, truncated or mutated dextransucrases which conserve their enzymatic activity or which conserve their specificity in the synthesis of ?-1,6 bonds and can produce, from saccharose, dextrans with high molar mass and modified rheological properties compared with the properties of dextran obtained with the native enzyme and isomalto-oligosaccharides with a controlled molar mass and dextrans.
    Type: Grant
    Filed: June 23, 2016
    Date of Patent: July 10, 2018
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DE RECHERCHE AGRONOMIQUE, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSE
    Inventors: Pierre F. Monsan, Magali Remaud-Simeon, Gabrielle Potocki-Veronese, Claire Moulis
  • Publication number: 20180177540
    Abstract: Some embodiments are directed to a method for controlling the viscosity of orthopedic bone cement during its curing in percutaneous vertebroplasty by allowing a controlled heating and/or cooling of the cement during the injection that leads to a dynamic and full control of the viscosity of the cement during the injection.
    Type: Application
    Filed: June 24, 2016
    Publication date: June 28, 2018
    Applicants: UNIVERSITÉ DE STRASBOURG, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DES SCIENCES APPLIQUÉES
    Inventors: Nicole LEPOUTRE, Laurence MEYLHEUC, Gabriela Iuliana BARA, Bernard BAYLE
  • Patent number: 9994623
    Abstract: The invention relates to novel entomotoxic polypeptides of the family of albumins 1b in legumes. Said polypeptides can be especially used as insecticides.
    Type: Grant
    Filed: December 9, 2014
    Date of Patent: June 12, 2018
    Assignees: INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON
    Inventors: Corinne Royer, Pedro Da Silva, Frédéric Gressent, Lamis Karaki, Yvan Rahbe
  • Patent number: 9975764
    Abstract: Method for producing a directed monolayer or multilayer assembly of colloidal nanoparticles attached to an electret substrate, including imparting a surface electric potential to an electret substrate according to a pattern of positive and/or negative electric charges, and contacting an electret substrate with a colloidal dispersion. The colloidal dispersion has electrically neutral or near neutral and electrically polarizable colloidal nanoparticles, and a nonpolarizing or weakly polarizing dispersion medium. The absolute value of the surface electric potential and the concentration of polarizable nanoparticles are no lower than a first surface electric potential threshold and no lower than a second concentration threshold, respectively, such as to obtain an assembly having a desired geometric shape, at least the first layer of which is compact in terms of the absence of undesired gaps having sizes greater than the size of two adjacent nanoparticles, preferably not greater than the size of one nanoparticle.
    Type: Grant
    Filed: February 27, 2014
    Date of Patent: May 22, 2018
    Assignees: Institut National des Sciences Appliquees de Toulouse, Centre National de la Recherche Scientifique, Universite Paul Sabatier Toulouse III
    Inventors: Laurence Ressier, Sangeetha Neralagatta Munikrishnaiah, Pierre Moutet
  • Publication number: 20180126566
    Abstract: The invention relates to a load-balancing device for an articulated arm capable of receiving a load having a weight, the balancing device being characterized in that it comprising a support system able to be fastened to a stationary element of the articulated arm, and an actuator element capable of being attached to a movable input element of the articulated arm, the balancing device also including a lever arm able to exert a force on the actuator element in order to apply said force on the input element of the articulated arm, the lever arm having an adjustable length as a function of the weight of the load.
    Type: Application
    Filed: December 18, 2015
    Publication date: May 10, 2018
    Applicants: Centre national de la recherche scientifique, Ecole Centrale de Nantes, Institut National des Sciences Appliquées
    Inventors: Sébastien BRIOT, Vigen ARAKELYAN
  • Patent number: 9926453
    Abstract: A method for coating a surface comprises applying a layer of coating composition onto the surface, mechanically forming parallel ribs on the layer, and simultaneously polymerizing the layer with ultraviolet radiations. The coating composition comprises a mass percentage of urethan-acrylate oligomer, with an average molar mass in number between 1000 and 5000 g·mol?1, between 35% and 75%. The coating composition further comprises a mass percentage of a diluting agent, copolymerizable with urethan-acrylate oligomers, between 15% and 60%, and a mass percentage of pyrogenic silica between 0.5% and 5%.
    Type: Grant
    Filed: December 22, 2010
    Date of Patent: March 27, 2018
    Assignees: AIRBUS, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON
    Inventors: Elisa Campazzi, Jocelyne Galy, Franck Gaudin, Jean-François Gerard, Martine Villatte
  • Patent number: 9905872
    Abstract: The invention relates to a process for preparing a composite material comprising a fluorinated polymeric matrix and a filler consisting in ion exchange inorganic particles comprising a step for in situ synthesis of said particles within the polymeric matrix, said matrix comprising at least one first copolymer comprising at least two types of fluorinated recurrent units, a type of which bears at least one pendant maleic anhydride group.
    Type: Grant
    Filed: April 22, 2014
    Date of Patent: February 27, 2018
    Assignees: COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES, INSTITUT NATIONAL DES SCIENCES APPLIQUEES, ARKEMA FRANCE
    Inventors: Jean-François Gerard, Véronique Bounor Legare, Sérigne Seck, Pierrick Buvat, Janick Bigarre, Benoît Blondel, Jérôme Chauveau
  • Patent number: 9882280
    Abstract: A dihedral shaped device is provided, which includes two plates forming between them an angle of [pi]?2[alpha], where 0<[alpha]<[pi]/4. Each plate has a ground plane, at least one dielectric layer and a network of radiating elements. An incident wave is reflected by the device by virtue of a double reflection from both plates. The network of radiating elements of each plate allows a phase shift to be generated, from the exterior towards the centre of the dihedron, along an axis perpendicular to an axis of intersection of the two plates, according to a set phase law, allowing a deviation to be introduced relative to a specular reflection for a given operating frequency.
    Type: Grant
    Filed: November 7, 2013
    Date of Patent: January 30, 2018
    Assignees: INSTITUT NATIONAL DES SCIENCES APPLIQUEES, CNRS—CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Raphael Gillard, Stephane Meric
  • Publication number: 20170355870
    Abstract: The invention relates to a composition comprising at least one electroactive fluorinated terpolymer, and at least one second polymer compatible with the electroactive fluorinated terpolymer and having a glass transition temperature lower than that of the electroactive fluorinated terpolymer. The invention also relates to a method for producing said composition, and to a device such as an actuator comprising a substrate and a film of the above-mentioned composition.
    Type: Application
    Filed: January 11, 2016
    Publication date: December 14, 2017
    Applicants: ARKEMA FRANCE, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON
    Inventors: Fabrice DOMINGUES DOS SANTOS, Thierry LANNUZEL, Jean-Fabien CAPSAL, Pierre-Jean COTTINET, Jeremy GALINEAU, Minh-Quyen LE
  • Patent number: 9819198
    Abstract: This invention relates to an electronic system including a radiative electromagnetic emitter for emitting an activation signal including sequentially an energy supply signal followed by an identification signal, the power of the energy supply signal being at least ten times greater than the power of the identification signal, further including an interface connected to an energy supply source; an electric load; a circuit for deactivating a placing of electric load on standby, including: a receiver including a reception interface, a rectifier configured to generate a DC activation voltage on the basis of an activation signal, a switch configured to selectively connect/disconnect to the load from the energy supply, an identification circuit configured to extract an identifier of the activation signal and configured to apply the activation voltage as closure control signal for turning off the switch if a match of the identifier is determined.
    Type: Grant
    Filed: March 7, 2013
    Date of Patent: November 14, 2017
    Assignees: Ecole Centrale De Lyon, Universite Lyon 1 Claude Bernard, Institut National Des Sciences Appiquees De Lyon, University De Limoges, Centre National De La Recherch
    Inventors: Christian Vollaire, Marc Thevenot, Vlad Marian, Cyrille Menudier
  • Publication number: 20170313998
    Abstract: The present invention relates to a new isolated polypeptide comprising an amino acid sequence having at least 94%, 95%, 99% or 100% identity to the full length amino acid sequence set forth in SEQ ID NO: 1, and having a polyester degrading activity, and uses thereof.
    Type: Application
    Filed: October 20, 2015
    Publication date: November 2, 2017
    Applicants: CARBIOS, INSTITUT NATIONAL DE LA RECHERCHE AGRONONIQUE, INSTITUT NATIONAL DES SCIENCES APPLIQUEES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: PABLO ALVAREZ, EMILIE AMILLASTRE, SOPHIE DUQUESNE, ALAIN MARTY
  • Patent number: 9802061
    Abstract: The disclosure is related to an apparatus and method for charged hadron therapy verification. The apparatus comprises a collimator comprising a plurality of collimator slabs of a given thickness, spaced apart so as to form an array of mutually slit-shaped openings, configured to be placed at a right angle to the beam line, so as to allow the passage of prompt gammas from the target, the collimator being defined at least by three geometrical parameters being the width and depth of the slit-shaped openings and a fill factor. The disclosure is also related to a method for charged hadron therapy verification with a multi-slit camera.
    Type: Grant
    Filed: May 8, 2015
    Date of Patent: October 31, 2017
    Assignees: Ion Beam Applications S.A., Université Claude Bernard Lyon 1, Institut National des Science Appliquées de Lyon, Centre National de Recherche Scientifique (CNRS)
    Inventors: Nicolas Freud, Frauke Roellinghoff, Etienne Testa, Marco Pinto, Julien Smeets
  • Patent number: 9797847
    Abstract: A device for the imaging of an object to be studied, combines: a prism made from a material with no losses (non-absorbent) for radiation in the microwave range; a sample holder on a front face of the prism for receiving the object to be studied; and a mobile emitting antenna on a rear face of the prism in order to emit radiation in the microwave range.
    Type: Grant
    Filed: March 28, 2014
    Date of Patent: October 24, 2017
    Assignees: Institut National Des Sciences Appliquees De Lyon, Centre National De La Recherche Scientifique (CNRS), Universite Claude Bernard Lyon 1, Universite D'Aix Marseille
    Inventors: Rodolphe Vaillon, Bernard Lacroix, Jean-Michel Geffrin, Mathieu Francoeur
  • Patent number: 9782224
    Abstract: A device for selectively grasping a part of a separate elongated body extending through the device, includes at least three partially mobile jaw members defining between them a through hole of variable diameter depending on their mutual relative positioning, supporting and driving elements to which the jaw members are mounted and which are adapted to provide a coordinated motion to the members around the elongated body situated in the variable through hole, resulting in a closing or opening of the through hole. The jaw members have an elongated shape with two opposed ends and the supporting and driving elements include a circular or annular support body to which a first end of each jaw member is connected and a mobile annular driving body to which a second opposed end of each jaw member is connected.
    Type: Grant
    Filed: August 9, 2013
    Date of Patent: October 10, 2017
    Assignees: UNIVERSITE DE STRASBOURG (ETABLISSEMENT PUBLIC NATIONAL A CARACTERE SCIENTIFIQUE, CULTUREL ET PROFESSIONNEL), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (ETABLISSEMENT PUBLIC NATIONAL A CARACTERE SCIENTIFIQUE ET TECHNOLOGIQUE), INSTITUT HOSPITALO-UNIVERSITAIRE DE CHIRURGIE MINI-INVASIVE (GUIDEE PAR L'IMAGE), INSTITUT NATIONAL DES SCIENCES APPLIQUEES (ESTABLISSEMENT PUBLIC NATIONAL A CARACTERE SCIENTIFIQUE, CULTUREL ET PROFESSIONNEL)
    Inventors: Olivier Piccin, Nitish Kumar, Laurence Meylheuc, Laurent Barbe, Bernard Bayle, Francois Schmitt
  • Publication number: 20170237988
    Abstract: Decoder, system and method for decoding multimedia data at the level of a terminal by managing the energy available for decoding comprising a decoder of the multimedia data, characterized in that said decoder comprises at least one low-consumption decoding chain comprising an activation module suitable for activating a first low-consumption decoding chain or loop filter and a low-consumption interpolation chain as a function of at least one parameter representative of constraints of user energy and/or of the mobile terminal and of one or more metadata Md associated with a decoding complexity and/or with a decoding energy.
    Type: Application
    Filed: October 16, 2015
    Publication date: August 17, 2017
    Applicants: INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE RENNE S, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Erwan NOGUES, Daniel MENARD, Maxime PELCAT, Erwan RAFFIN
  • Patent number: 9726598
    Abstract: A device for characterizing a fluid medium with the help of a photoelectric transducer comprises at least one semiconductor substrate possessing at least one space charge zone and presenting a reception surface for receiving the fluid medium in order to constitute an interface between the substrate and the fluid medium, a production system for producing a spot light beam that is amplitude-modulated and that lights at least one zone of the interface through the fluid medium, a measurement system for measuring values of a photoelectric magnitude delivered while performing the lighting so as to create a matrix of values of the photoelectric magnitude, and a processor system for processing values of the photoelectric magnitude delivered by the measurement system and adapted to use the matrix to determine an electronic signature characteristic of the fluid medium.
    Type: Grant
    Filed: December 17, 2013
    Date of Patent: August 8, 2017
    Assignees: Centre National de la Recherche Scientifique, Ecole Centrale de Lyon, Institut National des Sciences Appliquees de Lyon, Universite Claude Bernard Lyon I, Universite T. Chevtchenko de Kiev
    Inventors: Sergeii Lytvynenko, Dmytro Beilobrov, Volodymyr Lysenko, Valeriy Skryshevskyy