Patents Assigned to Institute for Basic Science
  • Patent number: 11905445
    Abstract: According to the present invention, an organic light-emitting composite and a method of manufacturing the organic light-emitting composite are provided. According to exemplary embodiments, an organic light-emitting composite includes a polymer matrix; a first light-emitting material provided in the polymer matrix; and a second light-emitting material provided in the polymer matrix and obtained by oxidizing the first light-emitting material, wherein the second light-emitting material may have the same molecular weight as that of the first light emitting-material.
    Type: Grant
    Filed: January 22, 2019
    Date of Patent: February 20, 2024
    Assignees: POSTECH ACADEMY-INDUSTRY FOUNDATION, INSTITUTE FOR BASIC SCIENCE
    Inventors: Hee Cheul Choi, Jin Young Koo, Minkyung Lee
  • Patent number: 11879183
    Abstract: The present invention relates to a manufacturing method for single crystalline metal foil including: thermally treating poly-crystalline metal foil positioned to be spaced apart from a base to manufacture single crystalline metal foil, and a single crystalline metal foil manufactured thereby. According to the present invention, single crystalline metal foil having a large area may be obtained by thermally treating the poly-crystalline metal foil under a condition at which stress applied to the poly-crystalline metal foil is minimized.
    Type: Grant
    Filed: June 22, 2021
    Date of Patent: January 23, 2024
    Assignees: INSTITUTE FOR BASIC SCIENCE, UNIST (ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY)
    Inventors: Rodney S. Ruoff, Sunghwan Jin
  • Publication number: 20240007298
    Abstract: Disclosed is an electronic device for computing a solution to a linear system using a block matrix. The electronic device includes a memory configured to store data, and a processor configured to perform a plurality of operations by executing instructions. The electronic device computes the solution to the linear system without directly computing an inverse matrix R?1 of a block matrix R, using an inverse matrix of at least one of a plurality of sub-blocks matrices A, B, C, and D that constitute a block matrix R representing the linear system, and an inverse matrix of at least one of combinations of the plurality of sub-block matrices A, B, C, and D. According, the solution to the linear system can be efficiently computed.
    Type: Application
    Filed: October 31, 2022
    Publication date: January 4, 2024
    Applicant: INSTITUTE FOR BASIC SCIENCE
    Inventor: Kyung Ah SHIM
  • Patent number: 11785348
    Abstract: Disclosed are an endoscopic reflection microscope using an optical fiber bundle and an image acquisition method using the same. The endoscopic reflection microscope includes an incident wave output unit configured to output an incident wave to a target object through any one optical fiber in an optical fiber bundle, a reflected wave receiver configured to receive a reflected wave output from the target object in response to the incident wave through a plurality of corresponding optical fibers in the optical fiber bundle, and an image acquirer configured to establish a reflection matrix corresponding to the reflected wave and to acquire an image in which at least one of phase retardation of the incident wave or phase retardation of the reflected wave is compensated for based on the established reflection matrix.
    Type: Grant
    Filed: September 24, 2021
    Date of Patent: October 10, 2023
    Assignees: Korea University Research and Business Foundation, Institute for Basic Science
    Inventors: Won Shik Choi, Won Jun Choi, Mun Kyu Kang
  • Publication number: 20230272057
    Abstract: The present invention relates to mouse antibodies that bind to angiopoietin-2 (Ang2), humanized anti-Ang2 antibodies derived therefrom, and the use thereof. The anti-Ang2 antibodies have a dual function of activating the Tie2 receptor together with neutralizing Ang2. The anti-Ang2 antibodies show the property of normalizing abnormal and pathological blood vessels, and thus exhibits therapeutic efficacy against various diseases and disorders associated with abnormal blood vessels. The present invention further provides an angiogenesis inhibitor and a composition for treatment of diseases associated with abnormal Ang2 expression and Tie2 dysregulation, which comprise the antibody as an active ingredient, and a composition for diagnosing diseases associated with Ang2 inhibition and Tie2 activation, which comprises the antibody.
    Type: Application
    Filed: October 12, 2022
    Publication date: August 31, 2023
    Applicants: Institute for Basic Science, Korea Advanced Institute of Science and Technology
    Inventors: Gou Young Koh, Jeomil Bae, Mi Jeong Kim, Jin-Sung Park, Su Jin Seo, Jaeryung Kim, Jang Ryul Park, Pilhan Kim, Wangyuhl Oh
  • Publication number: 20230256417
    Abstract: The present application relates to a filter having a photocatalyst attached thereto, which comprises: a substrate; and a photocatalyst bonded on the substrate, in which the photocatalyst has each photocatalyst bonded and combined by a polymer binder, and the substrate and the photocatalyst are bonded by a hydrophilic polymer binder.
    Type: Application
    Filed: February 15, 2023
    Publication date: August 17, 2023
    Applicants: RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY, INSTITUTE FOR BASIC SCIENCE
    Inventors: Hyoyoung Lee, Jung Sue CHOI, Hak Sung LEE, Yeon Su HAN, Tae Hun YANG, Hyun KO
  • Publication number: 20230257892
    Abstract: The present disclosure relates to an electrolysis catalyst including a graphitic carbon layer; and a first metal and a second metal oxide dispersed in the graphitic carbon layer, wherein the first metal is electron-deficient.
    Type: Application
    Filed: February 15, 2023
    Publication date: August 17, 2023
    Applicants: RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY, INSTITUTE FOR BASIC SCIENCE
    Inventors: Hyoyoung Lee, Xinghui Liu
  • Patent number: 11660312
    Abstract: The present invention relates to a Bifidobacterium bifidum inducing regulatory T cells (Treg), a polysaccharide derived from Bifidobacterium bifidum, and a probiotic strain producing a polysaccharide and, more particularly, a polysaccharide containing ?-1-6-glucan as an effective ingredient, a probiotic strain producing ?-1-6-glucan, a food comprising the polysaccharide or strain as an effective ingredient for alleviation of immune disease or inflammatory disease, a therapeutic agent comprising the polysaccharide or strain as an effective ingredient for alleviation of immune disease or inflammatory disease, a method for preparing induced regulatory T cells (iTreg) by treatment with the polysaccharide or strain, and a cell therapy product for prevention or treatment of immune disease or inflammatory disease, comprising the induced regulatory T cells prepared by the method.
    Type: Grant
    Filed: June 14, 2018
    Date of Patent: May 30, 2023
    Assignees: INSTITUTE FOR BASIC SCIENCE, POSTECH ACADEMY-INDUSTRY FOUNDATION
    Inventors: Sin-Hyeog Im, Ravi Verma, Changhon Lee
  • Patent number: 11648525
    Abstract: The present invention relates to a reaction method for forming a layered structure of immiscible liquid-phase concentric layers within a rotary reactor and a reaction system including the layered structure, and may provide a basis capable of efficiently performing a multistage reaction in terms of time and space.
    Type: Grant
    Filed: January 22, 2020
    Date of Patent: May 16, 2023
    Assignees: INSTITUTE FOR BASIC SCIENCE, UNIST(ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY)
    Inventors: Cybulski Olgierd, Dygas Miroslaw, Mikulak-klucznik Barbara, Sobolev Yaroslav, Grzybowski Bartosz A
  • Publication number: 20230088084
    Abstract: Disclosed is a method for preparing a graphyne including: supplying a precursor represented by the following Chemical Formula 1 to a chamber including a first zone and a second zone; vaporizing or subliming the precursor in the first zone; and depositing the precursor vaporized or sublimed in the second zone on a metal substrate to form the graphyne: (in Chemical Formula 1, X is carbon or nitrogen, and R1 to R3 may be selected from the group consisting of hydrogen, bromine, fluorine, chlorine, and iodine, respectively).
    Type: Application
    Filed: July 20, 2022
    Publication date: March 23, 2023
    Applicants: Research & Business Foundation Sungkyunkwan University, INSTITUTE FOR BASIC SCIENCE
    Inventors: Hyoyoung LEE, Sohyeon SEO, Jungsue CHOI
  • Patent number: 11550136
    Abstract: According to the present disclosure, an optical signal emitted from a single molecule is received to measure a central location of the single molecule while changing a phase of a structured illumination having a periodic pattern to measure a phase of a pattern in which a fluorescence intensity is periodically changed in accordance with a distance between the pattern and the single molecule while displacing the periodic pattern by a specific interval to measure the central location of the single molecule, thereby improving an accuracy of the central location of the single molecule with low photons and as a result, the resolution of the image may be enhanced.
    Type: Grant
    Filed: October 16, 2018
    Date of Patent: January 10, 2023
    Assignees: Korea University Research and Business Foundation, INSTITUTE FOR BASIC SCIENCE
    Inventors: Sang Hee Shim, Ji Woong Kwon
  • Publication number: 20220381695
    Abstract: A focus scan type imaging device for imaging a target object in a sample that induces aberration proposed. The device includes: a light source unit for emitting a beam; an optical interferometer for splitting the beam emitted from the light source into a sample wave and a reference wave, and providing an interference wave formed by interference between a reflection wave that is the sample wave reflected from the sample and the reference wave; a camera module for imaging the interference wave; a scanning mirror disposed on an optical path of the sample wave of the optical interferometer and configured to reflect the sample wave to cause the sample wave to scan the sample; a wavefront shaping modulator disposed on the optical path of the sample wave of the optical interferometer; and an imaging controller configured to operate in a phase map calculation mode and in an imaging mode.
    Type: Application
    Filed: October 12, 2020
    Publication date: December 1, 2022
    Applicants: Korea University Research and Business Foundation, INSTITUTE FOR BASIC SCIENCE
    Inventors: Won-Shik CHOI, Seok-Chan YOON, Ho-Jun LEE
  • Patent number: 11498962
    Abstract: The present invention relates to mouse antibodies that bind to angiopoietin-2 (Ang2), humanized anti-Ang2 antibodies derived therefrom, and the use thereof. The anti-Ang2 antibodies have a dual function of activating the Tie2 receptor together with neutralizing Ang2. The anti-Ang2 antibodies show the property of normalizing abnormal and pathological blood vessels, and thus exhibits therapeutic efficacy against various diseases and disorders associated with abnormal blood vessels. The present invention further provides an angiogenesis inhibitor and a composition for treatment of diseases associated with abnormal Ang2 expression and Tie2 dysregulation, which comprise the antibody as an active ingredient, and a composition for diagnosing diseases associated with Ang2 inhibition and Tie2 activation, which comprises the antibody.
    Type: Grant
    Filed: August 17, 2020
    Date of Patent: November 15, 2022
    Assignees: Institute for Basic Science, Korea Advanced Institute of Science and Technology
    Inventors: Gou Young Koh, Jeomil Bae, Mi Jeong Kim, Jin-Sung Park, Su Jin Seo, Jaeryung Kim, Jang Ryul Park, Pilhan Kim, Wangyuhl Oh
  • Publication number: 20220355282
    Abstract: The composite according to the present invention comprises: a mesoporous inorganic support having vacancy defects; and metal alloy nanoparticles dispersed in and bound to the mesoporous inorganic support and containing a precious metal element and an earth rare element. The composite according to the present invention has a very high specific surface area since the alloy is dispersed and present in the form of ultrafine nanoparticles in the porous support, and thus can show remarkably improved activity when used as a material for a chemical reaction, including a catalyst.
    Type: Application
    Filed: September 29, 2020
    Publication date: November 10, 2022
    Applicants: Institute For Basic Science, Korea Advanced Institute of Science and Technology
    Inventors: Ryong Ryoo, Jaeheon Kim, Changbum Jo, Jeongchul Kim
  • Patent number: 11491327
    Abstract: A bio electrode and a method of forming the same are provided. The bio electrode comprises a first core-shell nanowire/polymer composite comprising a first core-shell nanowire and a first polymer. The method of forming a bio electrode comprises a step of forming a core-shell nanowire by carrying out epitaxial growth of a biocompatible metal on a surface of a core comprising a conductive metal.
    Type: Grant
    Filed: September 4, 2018
    Date of Patent: November 8, 2022
    Assignees: Seoul National University R&DB Foundation, INSTITUTE FOR BASIC SCIENCE
    Inventors: Daehyeong Kim, Taeghwan Hyeon, Suji Choi, Sangihn Han, Dongjun Jung
  • Patent number: 11435505
    Abstract: A wavelength multiplexing device is disclosed. When light is irradiated on a first longitudinal end region of a metal nano-structure, surface plasmon polaritons are generated in the first longitudinal end region. The surface plasmon polaritons and the light are coupled with each other to form first coupled surface plasmon polaritons, wherein the first coupled surface plasmon polaritons propagate along and on a surface of the metal nano-structure. When the first coupled surface plasmon polaritons reach a two-dimensional material layer, excitons are induced in the two-dimensional material layer, wherein the induced excitons and the first coupled surface plasmon polaritons are coupled with each other to form second coupled surface plasmon polaritons. The second coupled surface plasmon polaritons propagate along and on a surface of the metal nano-structure toward a second longitudinal end thereof.
    Type: Grant
    Filed: June 1, 2020
    Date of Patent: September 6, 2022
    Assignees: Research & Business Foundation Sungkyunkwan University, INSTITUTE FOR BASIC SCIENCE
    Inventors: Hyun Seok Lee, Young Hee Lee
  • Patent number: 11437616
    Abstract: The disclosure describes a nanowire for an anode material of a lithium ion cell and a method of preparing the same. The nanowire includes silicon (Si) and germanium (Ge). The nanowire has a content of the silicon (Si) higher than a content of the germanium (Ge) at a surface thereof, and has the content of germanium (Ge) higher than the content of the silicon (Si) at an inner part thereof.
    Type: Grant
    Filed: March 13, 2019
    Date of Patent: September 6, 2022
    Assignees: INSTITUTE FOR BASIC SCIENCE, POSTECH ACADEMY-INDUSTRY FOUNDATION
    Inventors: Hee Cheul Choi, Hyungki Kim
  • Patent number: 11428851
    Abstract: A wavelength multiplexing device is disclosed. When light is irradiated on a first longitudinal end region of a metal nano-structure, surface plasmon polaritons are generated in the first longitudinal end region. The surface plasmon polaritons and the light are coupled with each other to form first coupled surface plasmon polaritons, wherein the first coupled surface plasmon polaritons propagate along and on a surface of the metal nano-structure. When the first coupled surface plasmon polaritons reach a two-dimensional material layer, excitons are induced in the two-dimensional material layer, wherein the induced excitons and the first coupled surface plasmon polaritons are coupled with each other to form second coupled surface plasmon polaritons. The second coupled surface plasmon polaritons propagate along and on a surface of the metal nano-structure toward a second longitudinal end thereof.
    Type: Grant
    Filed: June 1, 2020
    Date of Patent: August 30, 2022
    Assignees: Research & Business Foundation Sungkyunkwan University, INSTITUTE FOR BASIC SCIENCE
    Inventors: Hyun Seok Lee, Young Hee Lee
  • Patent number: 11419534
    Abstract: A core-shell nanowire, a method of forming the core-shell nanowire and a stretchable composite comprising the core-shell nanowire are provided. The core-shell nanowire comprises a core comprising a conductive metal and a shell comprising a biocompatible metal. The method of forming the core-shell nanowire comprises a step of forming a core-shell nanowire by carrying out epitaxial growth of a biocompatible metal on a surface of a core comprising a conductive metal. The stretchable composite comprises a first core-shell nanowire/polymer composite comprising first core-shell nanowires and a first polymer, a first insulating layer disposed on the first core-shell nanowire/polymer composite, and a second core-shell nanowire/polymer composite disposed on the first insulating layer and comprising second core-shell nanowires and a second polymer.
    Type: Grant
    Filed: October 25, 2018
    Date of Patent: August 23, 2022
    Assignees: Seoul National University R&DB Foundation, INSTITUTE FOR BASIC SCIENCE
    Inventors: Taeghwan Hyeon, Daehyeong Kim, Sangihn Han, Suji Choi, Dongjun Jung
  • Publication number: 20220257964
    Abstract: The system for modulating the activity of cells according to an exemplary embodiment of the present invention may include a rotating magnetic field generating device which has an internal space in which a magnetic force generating unit and a living body can be disposed and forms a rotating magnetic field which satisfies Relationship Formulas 1 and 2 below; and magnetic particles disposed in the living body and capable of binding to a bioactive material and generating a torque when a rotating magnetic field is applied to transmit the torque to the bioactive material. |Mc|?1 mT??[Relationship Formula 1] |M75?Mc|/D75?5.0 T/m??[Relationship Formula 2] In Relationship Formulas 1 and 2 above, Mc is the strength of the magnetic field at the position of the rotation axis, D75 is the distance from the rotation axis to the 75% position of the distance to the magnetic force generating unit, and M75 is the strength of the magnetic field at the position D75.
    Type: Application
    Filed: February 17, 2022
    Publication date: August 18, 2022
    Applicants: UIF (University Industry Foundation), Yonsei University, Institute for Basic Science
    Inventors: Jin Woo CHEON, Jae Hyun LEE, Jung Uk LEE