Patents Assigned to Institute for Basic Science
  • Publication number: 20200110026
    Abstract: The present invention relates to a high-speed imaging system for measuring a target object within a sample, comprising: a light source emitting a plane wave; an angle-adjustment mirror adjusting an angle of the plane wave emitted from the light source; an optical interferometer dividing the plane wave whose angle was adjusted by the angle-adjustment mirror into a reference wave and a sample wave and forming an interference wave between the reference wave reflected from a reference mirror and the sample wave reflected from the target object; a camera module obtaining the interference wave, and an imaging controller controlling the angle-adjustment mirror to adjust the angle of the plane wave sequentially, forming a time-gated reflection matrix by using the interference waves obtained by the camera module in accordance with each angle of the plane wave, and imaging the target object based on the time-gated reflection matrix.
    Type: Application
    Filed: October 3, 2019
    Publication date: April 9, 2020
    Applicants: Korea University Research and Business Foundation, Institute For Basic Science
    Inventors: Won-Shik CHOI, Moon-Seok KIM, Yong-Hyeon JO, Seok-Chan YOON
  • Patent number: 10564043
    Abstract: The present invention relates to a apparatus and method for measuring a waveform of a light wave. A light wave measurement apparatus according to an embodiment of the present invention includes a pulse separation unit to separate an input light wave into a fundamental pulse and a signal pulse, a time delay adjustment unit to adjust a time delay between the fundamental pulse and the signal pulse, a focusing unit to focus the fundamental pulse and the signal pulse whose time delay is adjusted on an ionization material, and an ionization yield measurement unit to measure an ionization yield from electrons and/or ions generated by the focused fundamental pulse and signal pulse. The waveform of the input light wave is obtained by obtaining an ionization yield modulation changed by the signal pulse as a function of the time delay.
    Type: Grant
    Filed: May 17, 2018
    Date of Patent: February 18, 2020
    Assignees: Institute For Basic Science, Gwangju Institute of Science And Technology
    Inventors: Kyung-Taec Kim, Chang-Hee Nam, Seung-Beom Park, Wo-Sik Cho, Kyung-Seung Kim
  • Patent number: 10517963
    Abstract: Provided is a gene delivery including a polymer network formed by binding phenylboronic acid, sugar, and a low-molecular weight branched polymer. The gene delivery may be stably maintained in vivo and efficiently deliver a gene specifically to cancer cells, such that the gene delivery system may be usefully used as a gene delivery system for chemotherapy.
    Type: Grant
    Filed: October 28, 2016
    Date of Patent: December 31, 2019
    Assignees: Institute for Basic Science, POSTECH ACADEMY-INDUSTRY FOUNDATION
    Inventors: Won Jong Kim, Jinhwan Kim
  • Publication number: 20190200589
    Abstract: The present invention relates to: a transgenic Caenorhabditis elegans in which a glutamine tRNA 5? terminus-derived fragment (Gln 5?-tsRNA) is overexpressed; a preparation method therefor; and a method for screening for aging-associated factors by using the transgenic Caenorhabditis elegans. A transgenic Caenorhabditis elegans model provided in the present invention is an animal model in which Gln 5?-tsRNA is overexpressed such that aging is inhibited. When the model of the present invention is used, anti-aging mechanisms can be easily investigated, thereby significantly contributing to various research fields such as that of developing new anti-aging drugs and screening for age-inducing materials.
    Type: Application
    Filed: April 21, 2017
    Publication date: July 4, 2019
    Applicants: Postech Academy-Industry Foundation, Institute for Basic Science, Daegu Gyeongbuk Institute of Science
    Inventors: Hong Gil NAM, Gyoo Yeol JUNG, Seung Jae LEE, Woo Seon HWANG, Gi Won SHIN, Mi Hwa SEO
  • Patent number: 10301332
    Abstract: Provided is a method of controlling release of nitric oxide, and more particularly, to a method of selectively releasing nitric oxide depending on a change in pH using calcium phosphate. The method of selectively releasing nitric oxide according to the present invention may stably deliver nitric oxide to a desired site, and induce release of nitric oxide by a change in pH, thereby making it possible to improve a therapeutic effect while preventing a loss of nitric oxide.
    Type: Grant
    Filed: November 22, 2016
    Date of Patent: May 28, 2019
    Assignees: Institute for Basic Science, Postech Academy-Industry Foundation
    Inventors: Won Jong Kim, Jihoon Kim, Hyung Woo Choi
  • Patent number: 10219779
    Abstract: An apparatus for generating a 3D left ventricle image includes: an ultrasonic sensor transmitting ultrasonic waves to the heart and receiving echoes thereof, an image processor acquiring a plurality of 2D left ventricle images based on the echoes of the ultrasonic waves and extracting sets of left ventricle boundary coordinates from the plurality of 2D images, respectively and a controller calculating a position of the left ventricle in 3D space through transformation of the sets of left ventricle boundary coordinates extracted by the image processor and generating a 3D left ventricle image based on the position of the left ventricle in 3D space.
    Type: Grant
    Filed: June 16, 2015
    Date of Patent: March 5, 2019
    Assignee: Institute for Basic Science
    Inventors: Chi Young Ahn, Ki Wan Jeon, Sang Woon Yun
  • Patent number: 10082385
    Abstract: A system for measuring displacement of an accelerating tube by using a micro-alignment telescope, which includes a vacuum chamber; a hollow accelerating tube in the vacuum chamber; a sighting target attached to a surface of the accelerating tube while protruding from the surface of the accelerating tube; the micro-alignment telescope spaced apart from one side surface of the vacuum chamber; a first lens device interposed between the micro-alignment telescope and the vacuum chamber; and a second lens device spaced apart from an opposite side surface of the vacuum chamber by a distance, wherein the vacuum chamber includes first and second viewports placed on the surfaces of the vacuum chamber in correspondence with each other, and the micro-alignment telescope, the first lens device, the first viewport, the sighting target, the second viewport and the second lens device are aligned on a same axis in one direction.
    Type: Grant
    Filed: May 20, 2016
    Date of Patent: September 25, 2018
    Assignee: Institute for Basic Science
    Inventors: Min-Ki Lee, Young-Kwon Kim, Yong-Woo Jo, Jong-Wan Choi, Woo-Kang Kim, Hee-Tae Kim
  • Publication number: 20180266891
    Abstract: The present invention relates to a apparatus and method for measuring a waveform of a light wave. A light wave measurement apparatus according to an embodiment of the present invention includes a pulse separation unit to separate an input light wave into a fundamental pulse and a signal pulse, a time delay adjustment unit to adjust a time delay between the fundamental pulse and the signal pulse, a focusing unit to focus the fundamental pulse and the signal pulse whose time delay is adjusted on an ionization material, and an ionization yield measurement unit to measure an ionization yield from electrons and/or ions generated by the focused fundamental pulse and signal pulse. The waveform of the input light wave is obtained by obtaining an ionization yield modulation changed by the signal pulse as a function of the time delay.
    Type: Application
    Filed: May 17, 2018
    Publication date: September 20, 2018
    Applicants: Institute for Basic Science, Gwangju Institute of Science and Technology
    Inventors: Kyung-Taec KIM, Chang-Hee Nam, Seung-Beom Park, Wo-Sik Cho, Kyung-Seung Kim
  • Publication number: 20180145342
    Abstract: A flow field including graphene foam for a fuel cell. The flow field is made of graphene foam that enhances mass transport and suffers no corrosion under operating conditions of the fuel cell when compared with conventional flow fields. In addition, compressed graphene foam has smaller in-plane pores due to the compression and has more tortuous pathways for flowing reactants, thereby increasing retention time of reactants and accelerating diffusion of reactants into a gas diffusion layer (GDL). Further, large through-plane pores inside the graphene foam transport reactants to entire areas of a catalyst layer, and faster flow velocity compared with the conventional membrane electrode assembly (MEA) is derived from a decreased flow field width due to compression. Therefore, mass transport of reactants and products is enhanced, and performance of the fuel cell is improved at high current density regions.
    Type: Application
    Filed: November 16, 2017
    Publication date: May 24, 2018
    Applicants: Seoul National University, R&DB Foundation, Institute for Basic Science, Kangwon National University, University-Industry Cooperation Foundation
    Inventors: Yung-Eun SUNG, Yong-Hun CHO, Ji Eun PARK, Chi-Yeong AHN, Sungjun KIM
  • Publication number: 20180145341
    Abstract: The present invention relates to a component including graphene foam and functioning as a flow field and a gas diffusion layer (GDL) for a fuel cell. More particularly, a component functioning as a flow field and a GDL for a fuel cell according to the present invention is made of graphene foam that enhances mass transport and suffers no corrosion under operating conditions of the fuel cell when compared with a conventional flow field, thereby realizing excellent performance and durability. Furthermore, the component functions as the GDL so a thickness of a membrane electrode assembly is reduced thereby improving cell performance significantly.
    Type: Application
    Filed: November 16, 2017
    Publication date: May 24, 2018
    Applicants: Seoul National University, R&DB Foundation, Institute for Basic Science, Kangwon National University, University-Industry Cooperation Foundation
    Inventors: Yung-Eun SUNG, Yong-Hun CHO, Ji Eun PARK, Chi-Yeong AHN, Sungjun KIM
  • Patent number: 9812333
    Abstract: Provided is a nanoscale patterning method using self-assembly, wherein nanoscale patterns having desirable shapes such as a lamella shape, a cylinder shape, and the like, may be formed by using a self-assembly property of a block copolymer, and low segment interaction caused in a structure of 10 nm or less which is a disadvantage of the block copolymer may be prevented. In addition, even though single photolithography is used, pattern density may double as that of the existing nano patterns, and pitch and cycle of the patterns may be controlled to thereby be largely utilized for electronic apparatuses requiring high integration of circuits such as a semiconductor device, and the like.
    Type: Grant
    Filed: December 26, 2014
    Date of Patent: November 7, 2017
    Assignees: Korea Advanced Institute of Science and Technology, Institute for Basic Science
    Inventors: Sang Ouk Kim, Hyoung-Seok Moon
  • Patent number: 9745329
    Abstract: Provided is a method of preparing a silylative-reduced N-heterocyclic compound by reducing an N-heteraromatic compound including a sp2 hybridized nitrogen atom while simultaneously introducing a silyl group into a beta-position with respect to a nitrogen atom of the N-heteroaromatic compound, using a silane compound, in the presence of an organoboron catalyst.
    Type: Grant
    Filed: January 29, 2015
    Date of Patent: August 29, 2017
    Assignees: Institute for Basic Science, Korea Advanced Institute of Science and Technology
    Inventors: Sukbok Chang, Sehoon Park, Narasimhulu Gandhamsetty, Seewon Joung, Sung-Woo Park
  • Publication number: 20170191123
    Abstract: The present invention relates to a method for analyzing a genotype using a target-specific nuclease and, specifically, to a method for diagnosing cancer or analyzing a genotype by removing wild type DNA or particular genotype DNA using a target-specific nuclease or a variant thereof to amplify or concentrate only a small amount of DNA which has a difference in variation, such as a mutation, or genotype, and to a method for separating target DNA sesusing a target-specific nuclease or a variant thereof. Such methods are novel paradigm methods contrary to existing simple target-specific nucleases for post-PCR recognition of normal genotype and carcinogenic genotype, and can be favorably used in the early diagnosis of cancer or analysis of similar genotypes.
    Type: Application
    Filed: May 28, 2015
    Publication date: July 6, 2017
    Applicants: Toolgen Incorporated, Institute for Basic Science
    Inventors: Jin Soo Kim, So Jung Kim, Seung Hwan Lee, Seok Joong Kim
  • Publication number: 20150366533
    Abstract: Disclosed is a method for generating a 3D image of a left ventricle of the heart. The method includes: acquiring, by an image processor, a 2D left ventricle image; extracting, by the image processor, left ventricle boundary coordinates from the 2D image; calculating, by a controller, a position of the left ventricle in 3D space through transformation of the extracted left ventricle boundary coordinates; and generating, by the controller, a 3D left ventricle image based on the calculated position of the left ventricle in 3D space.
    Type: Application
    Filed: June 16, 2015
    Publication date: December 24, 2015
    Applicant: Institute for Basic Science
    Inventors: Chi Young Ahn, Ki Wan Jeon, Sang Woon Yun
  • Publication number: 20150366531
    Abstract: Disclosed is an ultrasonic diagnostic apparatus.
    Type: Application
    Filed: June 16, 2015
    Publication date: December 24, 2015
    Applicant: Institute for Basic Science
    Inventors: Chi Young Ahn, Ki Wan Jeon, Jung II Choi
  • Patent number: 8891468
    Abstract: Disclosed herein are a content-based network system and a method of controlling the transmission of content therein. The content-based network system includes a plurality of user terminals, a plurality of access points, a plurality of content origin servers, and a transmission control device. The plurality of access points is wirelessly connected to the plurality of user terminals. The plurality of content origin servers provides content to the access points. The transmission control device determines the priority of transmission of the content based on the characteristics of the content and allocates channels and sets interfaces based on the determined priority of transmission of the content.
    Type: Grant
    Filed: May 31, 2012
    Date of Patent: November 18, 2014
    Assignee: Institute for Basic Science
    Inventor: Sangsu Jung
  • Patent number: 8806194
    Abstract: The present invention relate to a method for authenticating a low performance device, and more particularly, to a device authenticating method, in which a low performance device such as a smart meter of a smart grid is authenticated in a matrix operation instead of an exponential operation through a homomorphic hash function (HHF) of a non-square matrix M, so that the amount of operations required for authenticating the device can be reduced and the device can be safely authenticated even without a separate certificate authority.
    Type: Grant
    Filed: August 17, 2012
    Date of Patent: August 12, 2014
    Assignee: Institute For Basic Science
    Inventors: Young Sam Kim, Joon Heo, Mun Seok Jeong
  • Publication number: 20140040432
    Abstract: The present invention relate to a content caching device, and more particularly, to such a content caching device in which the priority of a content requested by a user terminal is calculated based on content usage features such as the number of requests or the latest request interval of the requested content, and the like, the requested content is controlled to be selectively stored in a short-term storage unit based on the calculated priority of the requested content, and among the contents stored in the short-term storage unit, a content needed to be stored for a long time period is controlled to be stored in a separate long-term storage unit based on the storage time of the requested content in the short-term storage unit.
    Type: Application
    Filed: October 15, 2012
    Publication date: February 6, 2014
    Applicant: Institute for Basic Science
    Inventors: Sangsu JUNG, Okyu KWON, Joon HEO
  • Patent number: 8543811
    Abstract: An identity-based ring signature authentication method provides an efficient identity-based ring signature method, which has a constant number of bilinear pairing computations independent the number of ring members in a verification process. The method does not use a special type of function, e.g., MapToPoint.
    Type: Grant
    Filed: December 8, 2011
    Date of Patent: September 24, 2013
    Assignee: Institute for Basic Science
    Inventors: Kyung Ah Shim, Young Ran Lee