Abstract: An ultrasound scanning system includes a graphical user interface that provides visually intuitive feedback to a user to assist the user in properly aligning an ultrasound scanner to a desired acquisition state. In addition to providing pose information, the feedback may direct the user as to a target contact force applied by the ultrasound scanner to a surface undergoing a scan.

Abstract: Some embodiments herein provide compositions and methods for expressing secreted and cell-surface-bound polypeptides in a single cell. In some embodiments, secreted and cell-surface polypeptide are produced from a single polynucleotide. The polynucleotide can comprise a sequence (or sequence encoding a polypeptide) that mediates separation of a membrane anchor from the polypeptide. In some embodiments, a desired ratio of secreted to surface-bound polypeptide is obtained by selecting a sequence that mediates a desired level of separation of the membrane anchor from the polypeptide.

Abstract: The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides vaccine nanocarriers capable of stimulating an immune response in T cells and/or B cells, in some embodiments, comprising at least one immunomodulatory agent, and optionally comprising at last one targeting moiety and optionally at least one immunostimulatory agent. The invention provides pharmaceutical compositions comprising inventive vaccine nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive vaccine nanocarriers and pharmaceutical compositions thereof. The invention provides methods of prophylaxis and/or treatment of diseases, disorders, and conditions comprising administering at least one inventive vaccine nanocarrier to a subject in need thereof.

Abstract: A fiber wadding for filling bone defects having a flocculent three-dimensional structure is disclosed. The fiber wadding includes a plurality of fibers that contain a biodegradable resin as a principal component and a siloxane. Outside diameter of the plurality of fibers of the wadding is from about 0.05 ?m to about 30 ?m. Bulk density of the fiber wadding is about 0.005-0.3 g/cm3.

Abstract: A solid-state circuit breaker for a DC power system which may operate unidirectional and bidirectional and does not require an external power supply to provide current interruption protection during an event of a short circuit fault.

Abstract: Systems and methods for the formation of nanostructures, including carbon-based nanostructures, are generally described. In certain embodiments, substrate configurations and associated methods are described.

Abstract: A model-based neuromechanical controller for a robotic limb having at least one joint includes a finite state machine configured to receive feedback data relating to the state of the robotic limb and to determine the state of the robotic limb, a muscle model processor configured to receive state information from the finite state machine and, using muscle geometry and reflex architecture information and a neuromuscular model, to determine at least one desired joint torque or stiffness command to be sent to the robotic limb, and a joint command processor configured to command the biomimetic torques and stiffnesses determined by the muscle model processor at the robotic limb joint. The feedback data is preferably provided by at least one sensor mounted at each joint of the robotic limb. In a preferred embodiment, the robotic limb is a leg and the finite state machine is synchronized to the leg gait cycle.

Abstract: An encoder generates a compressed data sequence from an original data sequence using many-to-one mapping independently of a source model associated with the original data sequence and without extracting the source model. A decoder uses both the source model associated with the original data sequence and the mapping applied during compression that is devoid of, in substance, the source model, to regenerate, at least in part, the original uncompressed data sequence from the compressed data sequence that does not include a significant portion of the source model.

Abstract: Network coding and multiple packet reception (MPR) are used together in a wireless network. In at least one implementation, a novel medium access control (MAC) protocol is provided that enhances throughput in a wireless mesh network that uses network coding and MPR by providing fairness to information flows, rather than fairness to individual nodes.

Abstract: A cysteine hydrazide nicotinamide (Cyhn) reagent designed for the enrichment of bacterial glycoproteins is provided. Methods for purification of free oligosaccharides and their analysis are also provided.

Abstract: Monomers and polymers, and a method of making polymers that retain the ability of the polymer to form reversible and irreversible bonds are provided. Gels comprising the polymers have the ability to coordinate metal ions and bind biopolymers.

Abstract: This disclosure relates to photovoltaic and photoelectrosynthetic cells, devices, methods of making and using the same.

Abstract: Provided is a piezoelectric material excellent in piezoelectricity. The piezoelectric material includes a perovskite-type complex oxide represented by the following General Formula (1). A(ZnxTi(1-x))yM(1-y)O3??(1) wherein A represents at least one kind of element containing at least a Bi element and selected from a trivalent metal element; M represents at least one kind of element of Fe, Al, Sc, Mn, Y, Ga, and Yb; x represents a numerical value satisfying 0.4?x?0.6; and y represents a numerical value satisfying 0.1?y?0.9.

Abstract: The invention relates to the production of one or more terpenoids through microbial engineering, and relates to the manufacture of products comprising terpenoids.

Abstract: The invention relates to recombinant expression of a taxadiene synthase enzyme and a geranylgeranyl diphosphate synthase (GGPPS) enzyme in cells and the production of terpenoids.

Abstract: A method for efficiently preparing ferrate based on nascent state interfacial activity. The method is as follows: (a) preparing nascent iron solution; (b) adding an oxidizing agent to the iron solution of step (a); (c) adding alkali solution or alkali particles to the mixed solution of step (b), mixing by stirring, and carrying out solid-liquid separation; (d) adding a stabilizing agent to the liquid separated out in step (c), and thus obtaining ferrate solution. The yield is 78-98%. The prepared ferrate solution is stable and can be stored for 3-15 days.

Abstract: A method of preparing a core-shell nanorod can include growing a shell of a core-shell nanorod (M1X1)M2X2 in a solution through a slow-injection of M2 precursor solution and X2 precursor solution, wherein the core-shell nanorod includes a M1X1 core.

Abstract: A system and method for manipulating devices, such as a medical implant arranged within a subject, is provided. For non-invasive manipulation of a medical implant, a subject having a non-ferromagnetic medical implant arranged therein is arranged within a system having a static magnetic field and a plurality of adjustable magnetic fields. The non-ferromagnetic medical implant includes at least one cavity and at least one ferromagnetic or ferrimagnetic material arranged within the at least one cavity. The plurality of adjustable magnetic fields of the system are controlled to induce forces on the at least one ferromagnetic or ferrimagnetic material arranged within the at least one cavity to thereby apply the induced forces to the non-ferromagnetic medical implant to effectuate a non-invasive, in vivo manipulation of the non-ferromagnetic medical implant. Other implementations include the manipulation devices such as robotic medical systems, using magnetic fields to drive the robotic medical system.

Abstract: A circuit for expanding a dynamic range. In one embodiment, the circuit includes: a transducer generating a signal current on an output terminal in response to a physical quantity, the signal current comprising an AC current and a DC current; a dynamic range enhancement circuit having a digital control signal input terminal and producing a variable opposition current in response to a digital signal applied to the digital control signal input terminal; an amplifier; an analog to digital converter in electrical communication with the amplifier; and a digital feedback circuit in communication with the output terminal of the analog to digital converter and in electrical communication with the digital control signal input terminal of the dynamic range enhancement circuit, wherein the opposition current from the dynamic range enhancement circuit is set substantially equal to the DC current portion of the signal current from the transducer.

Abstract: Methods and apparatus for modulating a particle pulse include a succession of Hermite-Gaussian optical modes that effectively construct a three-dimensional optical trap in the particle pulse's rest frame. Optical incidence angles between the propagation of the particle pulse and the optical pulse are tuned for improved compression. Particles pulses that can be modulated by these methods and apparatus include charged particles and particles with non-zero polarizability in the Rayleigh regime. Exact solutions to Maxwell's equations for first-order Hermite-Gaussian beams demonstrate single-electron pulse compression factors of more than 100 in both longitudinal and transverse dimensions. The methods and apparatus are useful in ultrafast electron imaging for both single- and multi-electron pulse compression, and as a means of circumventing temporal distortions in magnetic lenses when focusing ultra-short electron pulses.