Abstract: A preparation method of separation membrane is provided. First, a polyimide composition including a dissolvable polyimide, a crosslinking agent and a solvent is provided. The dissolvable polyimide is represented by formula 1: wherein B is a tetravalent organic group derived from a tetracarboxylic dianhydride containing aromatic group, A is a divalent organic group derived from a diamine containing aromatic group, A? is a divalent organic group derived from a diamine containing aromatic group and carboxylic acid group, and 0.1?X?0.9. The crosslinking agent is an aziridine crosslinking agent, an isocyanate crosslinking agent, an epoxy crosslinking agent, a diamine crosslinking agent, or a triamine crosslinking agent. A crosslinking process is performed on the polyimide composition. The polyimide composition which has been subjected to the crosslinking process is coated on a substrate to form a polyimide membrane. A wet phase inversion process is performed on the polyimide membrane.

Abstract: A detecting device includes a first coil, a third coil, a second coil, and a fourth coil. The first coil generates a first magnetic field on a to-be-measured object. The third coil generates a third magnetic field under the to-be measured object. The second coil generates a second magnetic field. After the fourth coil receives the second magnetic field, a voltage is induced. The induced voltage is amplified by an amplify circuit to drive the third coil. The directions of the currents generated by the first coil and the third coil, respectively, are the same.

Abstract: An intelligent system and method for preparing cryo-electron microscopy samples is provided. The system includes a control center, an ultra-low temperature liquid tank, a sample holding mechanism configured to limit a position of a to-be-processed sample, a sample processing mechanism configured to cut or polish the sample, a position adjustment mechanism, and a sample transfer mechanism configured to transfer a processed sample. In a working process, the control center controls the ultra-low temperature liquid tank to provide a preset temperature environment based on a target sample type, activates the position adjustment mechanism based on position information of the sample holding mechanism in the first chamber to drive the sample processing mechanism to perform processing according to a preset processing route, and activates, based on information about the processed sample to be transferred into the second chamber, the sample transfer mechanism to transfer the processed sample in a preset environment.

Abstract: The present invention relates to a protein binding to GARP in the presence of TGF-? and uses thereof.

Abstract: A method for detecting and repairing external diseases of a buried drainage pipeline includes steps of: S1, controlling a robot to enter the pipeline to perform comprehensive detection of pipeline diseases; S2, analyzing detected pipeline diseases with a computer terminal based on detection results of the robot, and determining locations of external diseases of the pipeline; S3, controlling the robot to detect a depth of the external diseases of the pipeline relative to a ground surface; S4, determining a projection position of the external diseases of the pipeline on the ground surface according to detection results of the step S2, and drilling a hole from the ground surface; determining a drilling depth according to detection results of the step S3, and inserting a grouting pipe; and S5, grouting and repairing the external diseases of the pipeline through the grouting pipe.

Abstract: A smart screw according to an embodiment may comprise: a screw main body which penetrates an artificial joint including a shell disposed on a hip joint of an object and a liner disposed on the inner surface of the shell and is then inserted into the hip joint; a transducer including a coupling layer that senses a sound wave signal reflected from the liner, a piezo-electric layer formed to determine a frequency of the sound wave signal, and a sound absorbing layer for absorbing the sound wave signal; and a processing module for generating a sound wave signal toward the liner and receiving the sound wave signal sensed by the coupling layer, measuring the thickness of the liner on the basis of the received sound wave signal, and transferring data about the measured thickness of the liner to the outside.

Abstract: Embodiments of nanostructures comprising metal oxide and methods for forming the nanostructure on surfaces are disclosed. In certain embodiments, the nanostructures can be formed on a substrate made of a nickel titanium alloy, resulting in a nanostructure containing both titanium oxide and nickel oxide. The nanostructure can include a lattice layer disposed on top of a nanotube layer. The distal surface of the lattice layer can have a titanium oxide to nickel oxide ratio of greater than 10:1, or about 17:1, resulting in a nanostructure that promotes human endothelial cell migration and proliferation at the interface between the lattice layer and human cells or tissue. The nanostructure may be formed on the outer surface of an implantable medical device, such a stent or an orthopedic implant (e.g. knee implant, bone screw, or bone staple).

Abstract: The present application discloses compounds which are activators of autophagic flux and pharmaceutical compositions comprising said activators. It further discloses use of said compounds and pharmaceutical compositions in the treatment of neurodegenerative diseases, particularly proteinopathies and tauopathies such as Alzheimer's disease. It further discloses methods of enhancing autophagic flux.

Abstract: The present invention provides a method, device, and system for adjusting a contention window size for performing channel access. The method includes: receiving uplink scheduling information on the uplink transmission including a new data indicator (NDI) associated with a specific subframe in a first uplink transmission burst; determining a contention window size based on the NDI; generating a random number N (N?0) in the determined contention window size based on the NDI associated with the specific subframe; and performing the uplink transmission on the specific cell after sensing a channel on the specific cell at least for N slots while the channel on the specific cell is idle. If the NDI is toggled, the contention window size is reset to a minimum value, and if the NDI is not toggled, the contention window size is increased to a next higher allowed value.

Abstract: A computing system displays an initial graph with icons. Each icon graphically represents data associated with a respective entity. The first icon is connected in the initial graph to other icon(s). The system receives an indication of a graphical network pattern. The graphical network pattern is defined by a user selection of a second icon in the initial graph and: a user selection of a third icon in the initial graph; or a user selection of a graphical representation in the initial graph of a relationship between the second icon and the third icon. The system sends computer instructions indicating a network pattern query for searching an electronic database for electronic record(s) corresponding to a queried network pattern. The system receives a dataset indicating located electronic record(s) corresponding to the queried network pattern. The system generates output data indicating an output graph for a graphical representation of the located record(s).

Abstract: A method for generating a nested container with no intersection and same layer full coverage, including: giving a right undirected graph G(V, E, W) and network measurement index set {Ti} for dividing nodes in G, each network measurement index Ti corresponding to a Ci layer container set {Ci k}; deleting an edge weighing greater than Ti, and segmenting G into subgraphs, each a connected component; setting all nodes in the subgraph Gcm not in the Ci layer container as set L; selecting one node from set L as current anchor aj; starting with anchor aj, performing breadth-first search on all nodes in L and Ci+1 layer container containing aj with the path communicated therewith less than Ti forming a Ci layer container with anchor aj; setting j?=j+1, determining whether L is a null set; setting m=m+1, determining whether all subgraphs are processed; setting i=i?1, and determining whether i=1 is satisfied.

Abstract: The present subject matter provides compositions, formulations, and methods for inhibiting, treating, or preventing aberrant angiogenesis in a subject.

Abstract: The present invention relates to inhibin analogs, their method of production and their use in the treatment and prophylaxis of disease or conditions associated with reduced levels of inhibin and activin-mediated signaling.

Abstract: Illustrative embodiments of technologies for nucleotide sequence screening are disclosed. In one illustrative embodiment, a system may include a server to communicate with a remote frontend over a network in order to receive a request to screen one or more nucleotide sequences for hazardous content and to report a result of the screening. The system may also include a compute engine to compare each nucleotide sequence to each of a plurality of reference sequences stored in a reference database, to detect whether hazardous content is present in each nucleotide sequence based upon the comparison of that nucleotide sequence to each of the plurality of reference sequences, and to assign one of a plurality of threat levels to each nucleotide sequence based upon the detection of whether hazardous content is present in that nucleotide sequence. The reported result may include the threat level assigned to each nucleotide sequence.

Abstract: Pharmaceutical compositions comprise a 1-ADP-heptose conjugate and may include an immunogen or an immune checkpoint inhibitor, and are used to promote an immune response.

Abstract: Disclosed herein is a composition including a recombinant nucleic acid sequence that encodes an antibody to a Middle East Respiratory Syncytial Coronavirus (MERS-CoV) viral antigen. Also disclosed herein is a method of generating a synthetic antibody in a subject by administering the composition to the subject. The disclosure also provides a method of preventing and/or treating an MERS-CoV virus infection in a subject using said composition and method of generation.

Abstract: Provided are: a peptide for regulating reactivity to a serotonin reuptake inhibitor-based antidepressant; a vector and a pharmaceutical composition for preventing or treating depression, which comprise same; a method for screening for an antidepressant by evaluating the activity of mossy cells; and the like.

Abstract: A light absorber includes an insulating substrate; a reflective layer that is provided on the insulating substrate, that is composed of a metal, and that has conductivity; a conductive pattern that is disposed on the reflective layer and that has defined therein at least one first opening; a nano-antenna that is disposed on the reflective layer and that vertically overlaps the at least one first opening; and an insulating pattern having a first portion that is interposed between the reflective layer and the conductive pattern and having a second portion that is interposed between and completely fills a vertical space between the reflective layer and the nano-antenna so that the reflective layer, the conductive pattern, and the nano-antenna are electrically insulated from each other.

Abstract: The invention is a special designed pattern heterogeneous substrate, which is epitaxially deposited on a heterogeneous substrate by two step growth, and a thermal cycle annealing is added to reduce the lattice mismatch between the layers and the difference in thermal expansion coefficient, thereby obtaining a better stress. The quality of the semiconductor epitaxial layer is improved, and the present invention can easily grasp the timing of stress release when the semiconductor is grown on the heterogeneous substrate, avoid cracks in the semiconductor epitaxial layer, and form a crack free zone in the middle of the semiconductor epitaxial layer.

Abstract: A conjugated cationic dendrimer comprising end groups conjugated to charge-shielding groups, wherein some charge-shielding groups are chemically linked to active pharmaceutical ingredients.