Abstract: An isolated protein comprises respective amino acid sequences of each of a plurality of CTL epitopes from two or more different herpesvirus antigens and further comprises an intervening amino acid or amino acid sequence between at least two of said CTL epitopes comprising proteasome liberation amino acids or amino acid sequences and, optionally, Transporter Associated with Antigen Processing recognition motifs. The isolated protein is capable of rapidly expanding human cytotoxic T lymphocytes (CTL) in vitro and eliciting a CTL immune response in vivo upon administration to an animal as an exogenous protein. Typically, the isolated protein comprises no more than twenty (20) CTL epitopes derived from cytomegalovirus and/or Epstein-Barr virus antigens.

Abstract: A catalyst for producing light aromatics with heavy aromatics, a method for preparing the catalyst, and a use thereof are disclosed. The catalyst comprises a carrier, component (1), and component (2), wherein component (1) comprises one metal element or more metal elements selected from a group consisting of Pt, Pd, Ir, and Rh, and component (2) comprises one metal element or more metal elements selected from a group consisting of IA group, IIA group, IIIA group, IVA group, IB group, IIB group, IIIB group, IVB group, VB group, VIB group, VIIB group, La group, and VIII group other than Pt, Pd, Ir, and Rh. The catalyst can be used for producing light aromatics with heavy aromatics, whereby heavy aromatics hydrogenation selectivity and light aromatics yield can be improved.

Abstract: The invention encompasses methods and test strips for detecting the presence of cerebrospinal fluid (CSF) in a biological sample comprising removing sialo-transferrin and selectively detecting or measuring asialo-transferrin in the biological sample.

Abstract: The present invention provides methods of screening for and diagnosing prostate cancer and methods of choosing a therapeutic for prostate cancer based on using KDM5D expression level to identify which patients with hormone sensitive prostate cancer benefit from primary castration and taxane and who with castration resistant prostate cancer would benefit from docetaxel plus an androgen receptor antagonists added to the ongoing castration. The disclosure also provides methods of screening for and diagnosing prostate cancer and methods of choosing a therapeutic for prostate cancer based on a lower KDM5D expression having a more aggressive clinical course of prostate cancer in human patients.

Abstract: The present disclosure is concerned with benzoannulene compounds that are capable of inhibiting a viral infection and methods of treating viral infections such as, for example, chikungunya, Venezuelan equine encephalitis, dengue, influenza, and zika, using these compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: A multi-dimensional micro fluid focussing device. The device includes an apparatus for multi-dimensional micro fluid focussing. The device also includes an analyser for analysing the focused fluid. The apparatus includes a microchannel having an inlet defining a first region, a middle region and an outlet defining a second region. A first junction is formed at the intersection of the first region and the middle region. A second junction is formed at the intersection of the middle region and the second region. A first sheath positioned proximal to the first junction and a second sheath positioned at the second junction. The junctions formed, along with the positioning of the sheaths enable the multi-dimensional focusing of the fluid. The analyser includes a holder for removably retaining the apparatus. A microscope is positioned across the holder. A recording unit is coupled to the microscope.

Abstract: A radar device according to an embodiment of the inventive concept includes a clock generator, a transmitter, a receiver, and a signal processor. The clock generator outputs the transmission clock, outputs the reception clock at the second time after the delay from the first time when the transmission clock is outputted, and generates the notification signal when the delay has the minimum value. The transmitter emits a transmission signal based on the transmission clock. The receiver receives an echo signal corresponding to the transmission signal, and generates a first signal corresponding to the echo signal based on the reception clock. The signal processor obtains a third time point at which a delay has the minimum value based on the notification signal.

Abstract: The present invention provides a catalyst electrode for oxygen evolution comprising an electrode current collector comprising a carbon fiber fabric, a nanowire layer comprising a metal oxide-based porous nanowire grown radially from the surface of the carbon fiber, and a porous carbon coating layer disposed around the outer surface of the nanowire, thereby maximizing the specific surface area and increasing the electron transfer rate, and thus exhibiting an excellent catalytic activity for oxygen evolution reaction, and a preparation method thereof.

Abstract: Provided is a neural network system for processing data transferred from an external memory. The neural network system includes an internal memory storing input data transferred from the external memory, an operator performing a multidimensional matrix operation by using the input data of the internal memory and transferring a result of the multidimensional array operation as output data to the internal memory, and a data moving controller controlling an exchange of the input data or the output data between the external memory and the internal memory. The data moving controller reorders a dimension order with respect to an access address of the external memory to generate an access address of the internal memory, for the multidimensional matrix operation.

Abstract: The present application discloses a portable thermoelectric potential detector, which is small in size and easy to carry. A portable thermoelectric potential detector includes a test fixture for fixing a sample to be tested, a probe assembly unit for detecting the sample to be tested, and a collection and control unit for controlling detecting of the probe assembly and collecting a voltage signal of the probe assembly; the probe assembly unit includes two probe assemblies, each probe assembly includes a probe for loading on the surface of the sample to be tested and a linear motor for driving the probe to move and load on the surface of the sample to be tested; the collection and control unit is electrically connected to the linear motor, and is further configured to transmit a first control signal for controlling a moving distance and a loading force of the linear motor.

Abstract: A preparation method and uses of a high-performance water-soluble acrylic resin with high solid content and low viscosity. The method polymerizes the free radical solution in a mixed solvent by a continuous method to produce an acrylic resin and the resin is rendered water-soluble through salification. Modification with versatate introduces a large branched structure. Silicone functional monomer is used to modify the acrylic resin. Amino resin is used as a curing agent to directly prepare a waterborne amino-acrylic coating with a simple process, and the coating has good hardness, fullness, water and alcohol resistance and salt spray resistance.

Abstract: Systems and methods for determining and indicating an energy range of a host vehicle. A sensor can be positioned to acquire data corresponding to an amount of energy stored in an energy storage system of the host vehicle. An anticipated operating condition for a forthcoming location of the host vehicle can be determined based on at least one operating condition provided from at least one of a plurality of vehicles that 1) has a vehicle type that is the same as a vehicle type of the host vehicle and 2) is located at a respective location that is proximate to the forthcoming location of the host vehicle. The remaining energy range can be determined based on 1) the amount of energy stored in the energy storage system and 2) the anticipated operating condition, and an output system of the host vehicle can indicate the remaining energy range for the host vehicle.

Abstract: Provided is a spiking neural network system for dynamical control of flexible, stable, and hybrid memory storage. An information storage method may include converting input information to a temporal pattern in a form of a spike; and storing the information that is converted to the temporal pattern in a spiking neural network. The storing may comprise storing information by applying, to the spiking neural network, a spike-timing-dependent plasticity (STDP) learning rate that is an unsupervised learning rule.

Abstract: A method for calibrating phase-frequency characteristics of low frequency accelerometer based on time-spatial synchronization, comprises: measuring excitation displacement of the low frequency accelerometer to realize excitation acceleration measurement of the low frequency accelerometer; realizing alignment of the excitation acceleration signal of the low frequency accelerometer with output voltage signal of the low frequency accelerometer in the spatial domain based on TSS technology, fitting the excitation acceleration signal and the output voltage signal respectively by SAM, and calculating phase ?F of the excitation acceleration signal at a zero position of horizontal long-stroke shaker and phase ?Z of the output voltage signal at the time when a zero encoder on the shaker outputs pulse; and calculating the sensitivity phase of the low frequency accelerometer with ?Z and ?F, and determining phase-frequency characteristics of the low frequency accelerometer by calibrating the sensitivity phases at differe

Abstract: The present invention relates to synthetic membranes and use of these synthetic membranes for isolation of volatile organic compounds and purification of water. The synthetic membrane includes a hydrophobic polymer layer located on a polymeric membrane support layer. The invention includes a method of isolating volatile organic compounds with the synthetic membrane by contacting a volatile organic mixture with the hydrophobic polymer layer of the synthetic membrane and removing volatile organic compounds from the polymeric membrane support layer of the synthetic membrane by a process of pervaporation. The invention also includes a method of purifying water with the synthetic membrane by contacting an ionic solution with the hydrophobic polymer layer of the synthetic membrane and removing water from the polymeric membrane support layer of the synthetic membrane by a process of reverse osmosis. The invention also relates to methods of isolating non-polar gases by gas fractionation.

Abstract: Provided is a face pose correction apparatus for correcting a face pose, using a person-specific frontal model specialized for input three-dimensional (3D) facial data. The face pose correction apparatus may comprise: a generation unit for generating corrected first facial data by performing a 3D rigid transformation of input 3D facial data on the basis of a pre-stored 3D standard facial model; and a correction unit for generating a first subject-specialized frontal model which is a bilateral symmetry model of the first facial data, and correcting the first facial data by performing the 3D rigid transformation of the first facial data on the basis of the generated first subject-specialized frontal model.

Abstract: Provided is a production method of kakeromycin and a derivative thereof showing an antifungal activity and cytotoxicity and expected as a new antifungal agent or anticancer agent, by chemical synthesis. A production method of a compound represented by the formula (1): wherein R is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group; and n is 0 or 1, or a salt thereof, including a step of subjecting a compound represented by the formula (2): wherein R and n are as defined above, or a salt thereof, to an oxidation reaction.

Abstract: The present invention discloses a method of re-transmission of a lost MMT packet by a packet transmission apparatus. The method includes generating a media processing unit (MPU) based on a media fragment unit (MFU) and generating an MMT asset by encapsulating the MPU; generating an MMT packet based on the MPU included in the generated MMT asset; and transmitting the generated MMT packet, wherein the method further comprises adding, in a signaling message related to re-transmission of the MMT packet, delay_constrained_ARQ_flag to indicate whether or not the MMT packet transmission apparatus supports a delay-constrained automatic repeat request (ARQ) function.

Abstract: Systems and methods for implementing confidential communications between nodes of a network provide reduced power consumption, require less memory, and provide improved security, relative to previously-known systems and method. Preferred embodiments implement protocol functions in hardware, as opposed to software, to yield some or all of the foregoing improvements. Some embodiments use a hashing circuit for multiple purposes, while maintaining its ability to compute successive intermediate hash values. Some embodiments improve security of systems using circuits configured to leverage a favorable data format.

Abstract: Various fentanyl derivatives are described. The derivatives exhibit high binding affinity to opioid receptors, but also have decreased blood brain permeability as compared to standard fentanyl. This, the resulting derivatives can be less addictive than standard fentanyl. Methods of making such derivatives are also disclosed in this document.