Abstract: A method and associated apparatus combine a calculation of chaos of a quantifiable cardiac characteristic associated with a patient with a measurement of a non-increasing parasympathetic activity of the patient to detect a physiological abnormality of the patient.
Abstract: The present invention provides a Peyer's patch activator containing a polysaccharide obtained from sugar cane as an active ingredient, wherein the polysaccharide contains ?-glucan as a main component and has a peak molecular weight within a range of 720,000 to 1,080,000, with a proportion of glucose in all component sugars being 80% or more, and proportions of nonreducing terminal glucose and ?-1,6-linked glucose being 20 to 30% and 15 to 25%, respectively.
Type:
Grant
Filed:
September 18, 2013
Date of Patent:
August 22, 2017
Assignees:
Mitsui Sugar Co., Ltd., The Kitasato Institute
Abstract: A wavelength converting member includes silica glass and a plurality of fluorescent material particles including an oxynitride or nitride fluorescent material and dispersed in the silica glass. The plurality of fluorescent material particles include at least two kinds of fluorescent material particles including (i) first fluorescent material particles that emit a fluorescence having a first peak wavelength and (ii) second fluorescent material particles that emit a fluorescence having a second peak wavelength. The wavelength converting member has a density within a range from 0.8 g/cm3 to 1.2 g/cm3.
Type:
Grant
Filed:
January 25, 2016
Date of Patent:
August 22, 2017
Assignees:
SHARP KABUSHIKI KAISHA, NATIONAL INSTITUTE FOR MATERIALS SCIENCE
Abstract: A network capable of being used in a datacenter is described. In some embodiments, the network can comprise a set of optical fiber rings, wherein each optical fiber ring carries data traffic on one or more wavelengths, and wherein each optical fiber ring is partitioned into multiple sectors. A reconfigurable optical add-drop multiplexer (ROADM) can be coupled to at least one optical fiber in each of at least two sectors. An electro-optical-switch can be coupled to each ROADM in each of the at least two sectors. A set of switches can be coupled to each electro-optical-switch in each of the at least two sectors. The set of switches can comprise a first layer of aggregation switches that is coupled to a second layer of edge switches, wherein the edge switches can be coupled to servers in a datacenter.
Abstract: The present invention is related to genomic nucleotide sequencing. In particular, the invention describes a paired end sequencing method that enables the sequencing of unique read pairs by co-localizing both 5? ends on a single emulsion polymerase chain reaction bead. The method may use a customized forked adaptor primer pair that is compatible with massively parallel sequencing techniques. The compositions and methods disclosed herein contemplate sequencing complex genomes, amplified genomic regions, as well as detecting chromosomal structural rearrangements.
Abstract: The invention provides proteins from group B streptococcus (Streptococcus agalactiae) and group A streptococcus (Streptococcus pyogenes), including amino acid sequences and the corresponding nucleotide sequences. Data are given to show that the proteins are useful antigens for vaccines, immunogenic compositions, and/or diagnostics. The proteins are also targets for antibiotics.
Type:
Grant
Filed:
May 26, 2016
Date of Patent:
August 22, 2017
Assignees:
Novartis AG, J. Craig Venter Institute, Inc.
Inventors:
John Telford, Vega Masignani, Maria Scarselli, Guido Grandi, Herve Tettelin, Claire Fraser
Abstract: A polymer and a pharmaceutical composition employing the same are disclosed. The polymer includes a first repeating unit, a second repeating unit, and a third repeating unit. In particular, the first repeating unit is the second repeating unit is wherein R1 is C1-6 alkyl group; and the third repeating unit is wherein X is and Y is a hydrophilic polymeric moiety.
Type:
Grant
Filed:
December 24, 2015
Date of Patent:
August 22, 2017
Assignee:
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Abstract: Disclosed herein is a method of using erythroid expression levels of RNF41 as a predictive biomarker for responsiveness to lenalidomide (LEN) in patients with non-del(5q) MDS.
Type:
Grant
Filed:
December 5, 2013
Date of Patent:
August 22, 2017
Assignee:
H. Lee Moffitt Cancer Center and Research Institute, Inc.
Abstract: A method for performing a non-contrast-enhanced magnetic resonance angiography (“MRA”) for a subject is provided. The method includes directing a magnetic resonance imaging (“MRI”) system to perform a pulse sequence to acquire k-space data from imaging slices that are oriented away from an axial direction of the subject. The method includes repeating the pulse sequence for a plurality of imaging slices, wherein a field-of-view (“FOV”) of at least one of the plurality of imaging slices is shifted by a predetermined value. The method also includes reconstructing, using the acquired k-space data, one or more angiographic images indicative of the subject's vasculature.
Abstract: A super resolution optofluidic microscope device comprises a body defining a fluid channel having a longitudinal axis and includes a surface layer proximal the fluid channel. The surface layer has a two-dimensional light detector array configured to receive light passing through the fluid channel and sample a sequence of subpixel shifted projection frames as an object moves through the fluid channel. The super resolution optofluidic microscope device further comprises a processor in electronic communication with the two-dimensional light detector array. The processor is configured to generate a high resolution image of the object using a super resolution algorithm, and based on the sequence of subpixel shifted projection frames and a motion vector of the object.
Type:
Grant
Filed:
March 23, 2011
Date of Patent:
August 22, 2017
Assignee:
California Institute of Technology
Inventors:
Guoan Zheng, Changhuei Yang, Samuel Yang, Seung Ah Lee
Abstract: The present invention relates to a composition including an Amomi Rotundus Fructus extract or a fraction thereof as an active ingredient, which can be used for the prevention, amelioration, or treatment of acute renal failure.
Type:
Grant
Filed:
November 6, 2013
Date of Patent:
August 22, 2017
Assignee:
KOREA INSTITUTE OF ORIENTAL MEDICINE
Inventors:
Hyun Kyoo Shin, Ju Young Jung, Hye Kyung Ha, Chang Seob Seo, Young Jung Kim
Abstract: The present invention provides a thin-film transistor in which transistor characteristics such as drain current and threshold voltage are improved, and a method of manufacturing the same. The present invention provides a thin-film transistor provided with a source electrode (108), a drain electrode (109), a semiconductor layer (105), a gate electrode (103), and an insulating layer (104); wherein the semiconductor layer (105) contains a composite metal oxide obtained by adding to a first metal oxide an oxide having an oxygen dissociation energy that is at least 200 kJ/mol greater than the oxygen dissociation energy of the first metal oxide, whereby the amount of oxygen vacancy is controlled; and the insulating layer (104) is provided with an SiO2 layer, a high-permittivity first layer, and a high-permittivity second layer, whereby the dipoles generated at the boundary between the SiO2 layer and the high-permittivity layers are used to control the threshold voltage.
Type:
Grant
Filed:
May 2, 2014
Date of Patent:
August 22, 2017
Assignee:
National Institute for Materials Science
Abstract: A battery for use in electronic devices and which is safely ingested into a body and a related method of making the battery. The battery includes an anode, a cathode and a quantum tunneling composite coating. The quantum tunneling composite coating covers at least a portion of at least one of the anode or the cathode and provides pressure sensitive conductive properties to the battery including a compressive stress threshold for conduction. The compressive stress threshold may be greater than a pre-determined applied stress in a digestive tract of the body in order to prevent harm if the battery is ingested. The battery may include a waterproof seal that extends between the quantum tunneling composite coating and a gasket separating the anode and cathode to inhibit the battery from short circuiting in a conductive fluid below the compressive stress threshold.
Type:
Grant
Filed:
March 5, 2014
Date of Patent:
August 22, 2017
Assignees:
Brigham and Women's Hospital, Inc., Massachusetts Institute of Technology
Inventors:
Bryan Laulicht, Janet Freilich, Jeffrey M. Karp, Robert Langer
Abstract: The present invention provides a novel dihydroorotic acid dehydrogenase inhibitor which is applicable to various diseases. When used as an active ingredient, a compound represented by formula (I): (wherein X represents a halogen atom, R1 represents a hydrogen atom, R2 represents an alkyl group containing 1 to 7 carbon atoms, R3 represents —CHO, and R4 represents —CH2—CH?C(CH3)—R0 (wherein R0 represents an alkyl group containing 1 to 12 carbon atoms which may have a substituent on the terminal carbon and/or on a non-terminal carbon, etc.)), an optical isomer thereof or a pharmaceutically acceptable salt thereof has a high inhibitory effect on dihydroorotic acid dehydrogenase and can be used as an immunosuppressive agent, a therapeutic agent for rheumatism, an anticancer agent, a therapeutic agent for graft rejection, an antiviral agent, an anti-H. pylori agent, a therapeutic agent for diabetes or the like.
Type:
Grant
Filed:
June 14, 2016
Date of Patent:
August 22, 2017
Assignee:
INSTITUTE OF MITOCHONDRIA SCIENCE, INC.
Inventors:
Kiyoshi Kita, Ken Daniel Inaoka, Hiroyuki Saimoto, Masaichi Yamamoto
Abstract: Methods and device for controlling optical scattering are disclosed. An array of 4-fold asymmetric cylinders can act as optical elements scattering electromagnetic waves, where the orientation and dimension of each optical element is determined according to the desired polarization and phase shift response of the device. A Jones matrix can be calculated to determine the fabrication parameters of the optical elements.
Abstract: An apparatus includes a processor and a storage storing instructions causing the processor to: receive a request for data concerning a target node and neighboring nodes; multiply an identifier of the target node with an index multiplier to determine a location of an index entry of the target node within an index data; access the index entry to retrieve an identifier of a window and an indication of a location within the window at which a node entry of the target node may be accessed, and to retrieve an indication of data size of the node entry; access the node entry within the identified window to retrieve an amount of the node entry up to the data size to retrieve at least one identifier of at least one neighboring node within a single degree of separation of the target node; and output the at least one identifier.
Abstract: A user equipment (UE), a device to device (D2D) UE, a backhaul device and a positioning method thereof are provided. The D2D UE measures an uplink reference signal transmitted from the UE and generates an uplink measurement report message according to the measured uplink reference signal. The backhaul device receives the uplink measurement report message and determines location information on at least one of the UE and D2D UE based on the uplink measurement report message.
Abstract: According to embodiments of the disclosure, a flexible electronic device is provided. The flexible electronic device includes a flexible substrate, at least one component and at least one stress buffer. The component may be disposed on the flexible substrate and having a lateral surface. The stress buffer may be disposed adjacent to the lateral surface of the component and has a stiffness which is getting larger toward the component.
Type:
Grant
Filed:
December 26, 2014
Date of Patent:
August 22, 2017
Assignee:
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Abstract: An elastic skin suit simulates gravitational loading. By selecting material(s) of appropriate dimensions and appropriate moduli of elasticity, and optionally integrating inelastic portions to maintain a desired surface distribution, the suit can be adapted to impose a loading regime that simulates the loading of terrestrial gravity in a more continuous, shoulder-to-ankle manner than current loading suits.
Type:
Grant
Filed:
July 7, 2014
Date of Patent:
August 22, 2017
Assignee:
Massachusetts Institute of Technology
Inventors:
James Murray Andrew Waldie, Dava Jean Newman
Abstract: The purpose of the present invention is to provide a computer mouse with an automatic grip angle control function for reducing a sense of wrist fatigue by continuously changing a grip angle in a constant period during use.
Type:
Grant
Filed:
December 23, 2013
Date of Patent:
August 22, 2017
Assignees:
UNIST (ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY), GWANGJU UNIVERSITY INSTITUDE FOR EDUCATIONAL-INDUSTRIAL COOPERATION