Abstract: An apparatus for generating burst-mode laser includes: a trigger signal generator for generating a burst trigger signal; a first light source for generating a first optical signal in a form of pulse; a second light source for generating a second optical signal in the form of pulse; an optical switch for selecting between the first optical signal and the second optical signal according to the burst trigger signal to output the selected one; an optical amplifier for amplifying the optical signal output from the optical switch; and a wavelength tuner for tuning a wavelength of the optical signal amplified by the optical amplifier. An oscillation line-width and/or a polarization state of the first optical signal are different from an oscillation line-width and/or a polarization state of the second optical signal.
Type:
Grant
Filed:
December 27, 2013
Date of Patent:
November 15, 2016
Assignee:
GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY
Abstract: A multiple oscillation-type generator includes: a first reciprocating member arranged inside a fluid and configured to reciprocate by lifting force, lowering force, or flow energy resulting from the fluid; a second reciprocating member arranged inside the fluid at a distance from the first reciprocating member and configured to reciprocate by lifting force, lowering force, or flow energy resulting from the fluid; a first conversion unit connected to the first reciprocating member and configured to convert reciprocating movements into rotational movements; a second conversion unit connected to the second reciprocating member and configured to convert reciprocating movements into rotational movements; a main power shaft configured to make rotational movements by rotational movements of the first conversion unit and the second conversion unit; and a generation unit configured to produce electric power using transferred rotational movements of the main power shaft.
Type:
Grant
Filed:
September 29, 2014
Date of Patent:
November 15, 2016
Assignee:
KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY
Inventors:
Jin Hwan Ko, Kwang-Soo Lee, Patar Ebenezer Sitorus
Abstract: A device and method is provided for a new and improved device for attaching tendon to bone wherein the intramedullary bone anchor, comprising a top section, a bottom section, a center section, a first end having a top inner portion and a top outer portion, a second end having a top inner portion and a top outer portion, and at least two holes extending from the top section through the bottom section, wherein the first end and second end are tapered and have seating geometry. The bone anchor is generally crescent-shaped or cylindrical.
Type:
Grant
Filed:
January 2, 2013
Date of Patent:
November 15, 2016
Assignee:
American Hand Institute, LLC
Inventors:
Tyson Cobb, Alejandro Badia, Stacey Berner, Steven Topper, Vincent van Donck
Abstract: A method for decomposing a target nucleic acid polymer, comprising: bonding a probe nucleic acid polymer and a microparticle to form a probe nucleic acid polymer-bonded microparticle, adding a target nucleic acid polymer to the probe nucleic acid polymer contained within the probe nucleic acid polymer-bonded microparticle to form an addition microparticle, and energizing the microparticle contained within the addition microparticle into a high-energy state and then using energy transfer from this high-energy state microparticle to decompose the target nucleic acid polymer.
Abstract: Embodiments of the present invention are directed to compositions and methods for anti-HIV (anti-CD4 binding site) potent VRC01-like (PVL) antibodies targeted to gp120 having an amino acid substitution in the heavy chain at a residue in the anti-CD4 binding site PVL antibody that is equivalent to Phe43 in CD4 and an amino acid substitution in the light chain, these antibodies having improved potency and breadth.
Type:
Grant
Filed:
December 13, 2012
Date of Patent:
November 15, 2016
Assignees:
THE ROCKEFELLER UNIVERSITY, CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventors:
Ron Diskin, Pamela J. Bjorkman, Michel Nussenzweig, Johannes Scheid
Abstract: A method, apparatus, and system are configured to recommend content using metadata including an event metadata unit, a searching unit, and a control unit. The event metadata generating unit is configured to generate event metadata regarding content selected by a user. The searching unit which, on the basis of the generated event metadata and social metadata regarding content uploaded to an SNS server associated with the user, is configured to search the content uploaded to the SNS server to recommend content to be provided to the user. The control unit is configured to provide the recommended content to the user using the social metadata regarding the searched recommended content.
Type:
Grant
Filed:
November 30, 2012
Date of Patent:
November 15, 2016
Assignee:
Korea Institute of Science and Techonology
Abstract: Novel hexon isolated from simian adenovirus serotype 19 encoded in the polynucleotide defined as SEQ ID NO: 3, hepervariable region thereof, chimeric adenovirus comprising the same, and therapeutic use thereof provides a solution to the problem of safety and effective systemic treatment for developing gene therapeutic agents using adenovirus.
Abstract: An electrophoresis chip that can be small and simple and that can analyze a sample with high accuracy is provided. The electrophoresis chip includes an upper substrate 4, a lower substrate 1, an introduction reservoir 2a, a recovery reservoir 2b and a capillary channel for sample analysis 3x. The introduction reservoir 2a and the recovery reservoir 2b are formed in the lower substrate 1. The introduction reservoir 2a and the recovery reservoir 2b are in communication with each other via the capillary channel for sample analysis 3x. The introduction reservoir 2a receives a sample to be measured. The sample is electrophoretically introduced directly into the capillary channel for sample analysis 3x by creating a potential difference between the introduction reservoir 2a and the recovery reservoir 2b, and is also analyzed in the capillary channel for sample analysis 3x during the separation of the sample while the sample is being continuously supplied.
Type:
Grant
Filed:
April 28, 2008
Date of Patent:
November 15, 2016
Assignees:
National Institute of Advanced Industrial Science and Technology, ARKRAY, Inc.
Abstract: A system for filtering a terminal location by combining WiFi location information and sensor information, the system includes a filter that filters an inaccurate location of a terminal by combining location information calculated from WiFi signals and sensor information, and by using indicators to remove abnormal location information.
Type:
Grant
Filed:
January 30, 2015
Date of Patent:
November 15, 2016
Assignee:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Young Su Cho, Myung In Ji, Joo Young Kim, Yang Koo Lee, Sang Joon Park, Jong Hyun Park
Abstract: Disclosed herein are materials and methods for treating cancer. In particular, compositions for stimulating tumor immunity through modulation of MFG-E8 are provided.
Abstract: A translation enhancer-driven positive feedback vector system is disclosed which is designed to facilitate identification of a Translational Enhancer Element (TEE) and to provide a means for overexpression of gene products. The system exploits both transcriptional and translational approaches to control the expression levels of genes and/or gene products. Methods are also disclosed for screening libraries of random nucleotide sequences to identify translational elements and for overproduction of proteins, which have uses in both research and industrial environments.
Type:
Grant
Filed:
May 18, 2015
Date of Patent:
November 15, 2016
Assignee:
The Scripps Research Institute
Inventors:
Vincent P. Mauro, Gerald M. Edelman, Wei Zhou
Abstract: An optical alignment device using pulse UV irradiates an alignment film with pulse UV to perform optical alignment of liquid crystal. The optical alignment device using pulse UV may include a chamber, a lamp which is installed at an upper portion of the chamber and emits pulse UV light, a stage which is provided at a lower portion of the chamber and on which a substrate having an alignment film formed on a surface thereof is placed, and a polarizer which is installed detachably between the stage and the lamp.
Type:
Grant
Filed:
November 25, 2013
Date of Patent:
November 15, 2016
Assignee:
Korea Institute of Industrial Technology
Inventors:
Gyo Jic Shin, Sang Kug Lee, Kyung Ho Choi
Abstract: A system and method are disclosed in which in a conventional non-grounding man-machine interface having no reaction base on the human body and for giving the existence of a virtual object and the impact force of a collision to a person, a haptic sensation of a torque, a force and the like can be continuously presented in the same direction, which cannot be presented by only the physical characteristic of a haptic sensation presentation device. In a haptic presentation device, the rotation velocity of at least one rotator in the haptic presentation device is controlled by a control device, and a vibration, a force or a torque as the physical characteristic is controlled, so that the user is made to conceive various haptic information of the vibration, force, torque or the like.
Type:
Grant
Filed:
August 31, 2015
Date of Patent:
November 15, 2016
Assignees:
National Institute of Advanced Industrial Science and Technology, Miraisens, Inc.
Abstract: A method of dynamic adjusting a generation frequency of messages in vehicular networks is provided, including: receiving updating requests and emergent degree of the vehicle event, and then determining whether the generation frequency of messages meets the dynamic change of the vehicle, if not satisfied, selecting a different adjustment method according to the event emergent degree. When the event is emergent, its generation frequency can be raised immediately by an interruptive adjustment and to suppress the generation frequency of messages of the others. Conversely, adjusting its generation frequency by a progressive adjustment and reducing the generation frequency of messages of the other lower-priority vehicles. According to the present disclosure, it prevents lower priority messages from occupying the channel overly, and emergency messages with higher priority can be satisfied immediately when it needed.
Type:
Grant
Filed:
July 23, 2014
Date of Patent:
November 15, 2016
Assignee:
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Abstract: Methods and compositions for inhibiting Nrf1 activity are provided for enhancing apoptosis in mammalian cells. Apoptosis is enhanced in mammalian cells by co-inhibiting Nrf1 activity and proteasome activity. Methods for identifying Nrf1 inhibitors are provided using an assay for screening Nrf1 inhibitors that enhance proteasome inhibition by preventing induced proteasome expression.
Type:
Grant
Filed:
November 8, 2010
Date of Patent:
November 15, 2016
Assignees:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventors:
Raymond J. Deshaies, Senthil Radhakrishnan, Candy S. Lee, Jefferson Y. Chan
Abstract: The present invention relates to a method for treating or preventing pathogenic infections in a subject having Cystic Fibrosis, COPD, and/or an open wound. This method involves selecting a subject having Cystic Fibrosis, COPD, and/or an open wound and administering to the selected subject a ceramidase under conditions effective to reduce ceramide and to treat or prevent the pathogenic infection. The method also involves the use of a ceramidase in combination with other drugs to reduce infection, reduce ceramide, or improve lung function in Cystic Fibrosis, COPD, and/or open wound patients.
Type:
Grant
Filed:
May 31, 2013
Date of Patent:
November 15, 2016
Assignees:
Icahn School of Medicine at Mount Sinai, Universitaet Duisberg-Essen, Yeda Research and Development Co. Ltd. at the Weizmann Institute of Science
Inventors:
Edward H. Schuchman, Erich Gulbins, Anthony Futerman, Yael Pewzner-Jung
Abstract: A MOSFET and a method for manufacturing the same are disclosed. The method comprises: a. providing a substrate (100), a dummy gate structure (200), a epitaxial protection layer (101) and a sacrificial spacer (205); b. covering the dummy gate structure (200) and the substrate (100) on one side thereof by a mask layer, and forming a vacancy (102) in the substrate; c. growing a semiconductor layer (300) on the semiconductor structure to fill in the vacancy (102); d. removing the epitaxial protection layer (101) and the sacrificial spacer (205), and sequentially forming source/drain extension regions, a spacer (201), source/drain regions, and an interlayer dielectric layer (500); and e. removing the dummy gate structure (200) to form a dummy gate vacancy, and forming a gate stack in the dummy gate vacancy. In the MOSFET structure of the present disclosure, negative effects of DIBL on device performance can be effectively reduced.
Type:
Grant
Filed:
October 22, 2013
Date of Patent:
November 15, 2016
Assignee:
INSTITUTE OF MICROELECTRONICS, CHINESE ACADEMY OF SCIENCES
Abstract: Disclosed is an electrochemical gas sensor using micro electro mechanical systems (MEMS). The MEMS electrochemical gas sensor includes: a substrate a lower central region of which is etched by a predetermined thickness; a first insulation film formed on the substrate; a heat emitting resistance body formed on the first insulation film; a second insulation film formed on the heat emitting resistance body; a reference electrode formed in an upper central region of the second insulation film; a solid electrolyte formed on the reference electrode; and a detection electrode formed on the solid electrolyte.
Type:
Grant
Filed:
September 14, 2012
Date of Patent:
November 15, 2016
Assignee:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Seung Eon Moon, Nak Jin Choi, Hyung Kun Lee, Jae Woo Lee, Woo Seok Yang, Jong Dae Kim
Abstract: The present invention provides compositions comprising hyaluronan with high elasticity, as well as methods for improving joint function, reducing pain associated with joint function and treating osteoarthritis by introducing into a joint a therapeutically effective amount of a composition comprising hyaluronan with high elasticity.
Abstract: Disclosed herein are an N-(pyrazolylmethyl)arylsulfonamide derivative useful as a calcium ion channel blocker, a pharmaceutically acceptable salt thereof, and the medicinal use thereof as a therapeutic agent using its calcium ion channel blocking effect.
Type:
Grant
Filed:
February 26, 2015
Date of Patent:
November 15, 2016
Assignee:
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventors:
Ghil Soo Nam, Kyung Il Choi, Jung Hyun Kim, Ae Nim Pae, Jin Ri Hong, Jae Kyun Lee