Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of malaria.

Abstract: The invention relates to a method for detecting RNA sequences. The invention also relates to nucleotide sequences, primers, probes and microarrays.

Abstract: The invention relates to pan pollen immunogens such as polypeptides, proteins and peptides, and methods and uses of such immunogens for modulating or relieving an immune response in a subject. For example, the immunogens can be used for treating a subject for an allergic immune response or inducing or promoting immunological tolerance to the immunogen or a pollen allergen in a subject.

Abstract: The present invention relates to a drug carrier having L-DNA nanocage structure prepared by using L-DNA, the mirror form of natural DNA, as a backbone. The drug carrier of the present invention has very superior cellular uptake efficiency and serum stability, so that it can be applied to deliver various drugs into cells usefully.

Abstract: A motorized walker is provided that can enable users to walk without being slowed by the walker and without needing to exert themselves to push the walker forward. The motorized walker provides additional haptic speed cues to inform the user's posture and locomotion control to prevent falling.

Abstract: A sensor can include a conductive region in electrical communication with at least two electrodes, the conductive region can include a complex, and the complex can include a carbon nanotube that is functionalized by a porphyrin.

Abstract: The present invention relates to the technical field of terminal devices of the Internet of Things, more specifically to a semantic method for terminal devices of the Internet of Things capable of analyzing the application characteristics of terminal devices of the Internet of Things, setting down the rules for building ontology base; analyzing and building initial ontology base by using the ontology base building tool; pre-processing information from network and sensors; collecting information uploaded by sensors, updating the initial ontology base, and expanding the ontology base by collecting information searched by network. The method establishes program plan by object-oriented mode, analyzes implementing results by using existing test data or simulated data, and realizes domain updating and expansion of sensor ontology according to specific applications. The whole development and evolution of sensor ontology is increasing gradually in a spiral form.

Abstract: A layered oxide material, a preparation method, an electrode, a secondary battery and use are disclosed. The layered oxide material has a general chemical formula NaxCuiFejMnkMyO2+?, in which M is an element that is doped for replacing the transition metals; x, y, i, j, k, and ? are respectively the molar ratios of respective elements, provided that x, y, i, j, k, and ? satisfy the relations: y+i++j+k=1, and x+my+2i+3j+4k=2(2+?), where 0.8?x?1, 0<i?0.3, 0<j?0.5, 0<k?0.5, 0.02???0.02, and m is the valence of M. The layered oxide material has a space group of R3m.

Abstract: The present invention relates to a method for producing a Polyporus squamosus-derived PSL1b recombinant lectin, which binds specifically to sialic acid containing glycoconjugates, from an Escherichia coli PSL1b strain (deposit number: KCTC12507BP) or a Pichia pastoris PSL1b strain (deposit number: KCTC12500BP) and a lectin produced thereby. The recombinant lectin of the present invention can be useful as an active ingredient of a composition or a kit for measuring or detecting glycoproteins, glycopeptides, glycolipids, sugar precursors, or oligosaccharides having sialic acid moieties.

Abstract: The present invention, in some aspects, provides methods, reagents, compositions, and kits for the radiolabeling of proteins, for example, of proteins useful for positron emission tomography (PET) or single-photon emission computed tomography (SPECT) (e.g., for diagnostic and therapeutic applications), using sortase-mediated transpeptidation reactions. Some aspects of this invention provide methods for the conjugation of an agent, for example, a radioactive agent or molecule to diagnostic or therapeutic peptides or proteins. Compositions comprising sortagged, radiolabeled proteins as well as reagents for generating radiolalebed proteins are also provided. Kits comprising reagents useful for the generation of radiolabeled proteins are provided, as are precursor proteins that comprise a sortase recognition motif.

Abstract: A method of screening solvents for the solubilization of petroleum hydrocarbons is disclosed. The method includes dissolving petroleum hydrocarbons in a selected solvent to form a first solution, adding an ionic liquid to the first solution and blending to form a second solution and measuring absorbance of the second solution using spectroscopic techniques. The solubilization of petroleum hydrocarbons in the solvent is then determined based on the difference between the measured absorbance of the first and second solution. A system for screening solvents for the solubilization of petroleum hydrocarbons is also disclosed. The system can be used in removal of wax deposition in refinery process equipment, process flow lines, during piping operations, upgradation of wax, prevention of clogging of pipelines, processing of sludge or for removing sludge from petroleum tank installations and enhancing the crude oil flow.

Abstract: Articles and methods comprising persistent carbenes are provided, as well as related compositions. In some embodiments, a persistent carbene may be associated with a portion of a substrate (e.g., at least a portion of a surface on the substrate). In certain embodiments, the association of persistent carbene with the substrate may be used to affect certain properties of substrate (e.g., surface chemistry, stability). In some cases, a persistent carbene may be functionalized after association with a portion of a substrate. In some embodiments, a persistent carbene and at least one secondary compound may be associated with a portion of a substrate. Articles and methods of the present invention may be useful for applications involving electronics, sensing, microfabrication, nanotechnology, biomimetic, and drug delivery, amongst others.

Abstract: This disclosure relates to methods and compositions useful for the treatment of cancer and diseases and disorders associated with autophagy.

Abstract: Organic metal compounds, organic light-emitting devices, and lighting devices employing the same are provided. The organic metal compound has a chemical structure represented by formula (I): wherein each R1 is independent and can be hydrogen, halogen, C1-10 alkyl group, C5-10 cycloalkyl group, or C5-12 aryl group; R2 is trialkyl silyl group; and L is a picolinic acid ligand, a 2-(imidazol-2-yl) pyridine ligand, a 2-(4,5-dimethyl-imidazol-2-yl) pyridine ligand, a 3-(trifluoromethyl)-5-(pyridine-2-yl)-1,2,4-triazolate ligand, or a 3-(isobutyl)-5-(pyridine-2-yl)-1,2,4-triazolate ligand.

Abstract: Autonomously operating analog to digital converters are formed into a two dimensional array. The array may incorporate digital signal processing functionality. Such an array is particularly well-suited for operation as a readout integrated circuit and in combination with a sensor array, forms a digital focal plane array.

Abstract: Provided herein is a system and method for providing a virtual desktop service using a cache server, the system including a host server configured to provide the virtual desktop service to a user's device using a virtual machine, a distributed file system configured to store data for the virtual machine, and a cache server configured to, when a request to process data reading is received from the virtual machine inside the host server, pre-read a data segment for the requested process of data reading from the distributed file system and store the pre-read data segment in a cache, and perform the process of data reading using the cache.

Abstract: Provided is an information processing system configured to: receive a plurality of images; select a standard image; search, in extracting partial images for complementing a too bright region/too dark region in the standard image from a reference images, using correction images obtained by subjecting each of the images to multivalued processing for each division of luminance components, for regions having matching shapes of respective regions included in the correction image of the standard image and the correction images of the other images; and complement image portions corresponding to the too bright region and/or too dark region in the correction image of the standard image using image portions, which are matching regions and correspond to appropriately bright regions, to thereby generate a synthetic image.

Abstract: A spatial light modulator is constituted by a plurality of pixels. A rearrangement optical element guides the light generated by the plurality of pixels of the spatial light modulator onto the screen to rearrange a plurality of pixels on a screen. Each lens of a lens array emits the light generated by the plurality of pixels rearranged on the screen as light beams in respective different directions. A control device controls the spatial light modulator such that a three-dimensional image is presented by the plurality of light beams emitted by a plurality of lenses of the lens array.

Abstract: An electronic device according to an embodiment of the present invention may include a display configured to display a first screen; a force direction sensing unit configured to detect a force direction of a contact applied to one point by an external object; and a control unit configured to sense an occurrence of a predetermined event to logically divide the display into at least two regions including a first region and a second region, acquire a force direction of a first contact associated with the predetermined event from the force direction sensing unit, determine a region from among the at least two regions to display the first screen according to the force direction of the first contact, and display the first screen on the determined region.

Abstract: Provided is a method of transmitting control information using a physical uplink shared channel (PUSCH) region in a system employing a multi-input multi-output (MIMO) antenna system in which transmission is performed through a plurality of layers. A method of transmitting a channel quality indicator (CQI)/precoding matrix indicator (PMI) using a PUSCH region in a system employing a MIMO antenna system in which transmission is performed through a plurality of layers includes encoding the CQI/PMI using one channel encoder, and transmitting the encoded CQI/PMI using some or all of the layers. Accordingly, it is possible to transmit uplink control information through a PUSCH region using a plurality of layers.