Abstract: Embodiments described herein relate to compositions including bridged bicyclic compounds such as iptycene-based structures and extended iptycene structures. In some embodiments, the compositions may be useful in organic light-emitting diodes (OLEDs), organic photovoltaics, and other devices.
Type:
Application
Filed:
March 23, 2016
Publication date:
September 29, 2016
Applicant:
Massachusetts Institute of Technology
Inventors:
Timothy M. Swager, Troy Andrew Van Voorhis, Marc A. Baldo, Tony Wu, Katsuaki Kawasumi, Tianyu Zhu
Abstract: The present invention provides methods for treating cancer using combinations of bromodomain and extra-terminal (BET) protein inhibitors and certain chemotherapeutic drugs.
Type:
Application
Filed:
November 7, 2014
Publication date:
September 29, 2016
Applicant:
Dana-Farber Cancer Institute, Inc.
Inventors:
James E. Bradner, Michael R. McKeown, Margaret A. Shipp, Bjoern Chapuy, Kwok-kin Wong, Zhao Chen
Abstract: In one aspect, the present disclosure involves a re-aeration device and re-aeration method for constructed wetland. In one aspect, the re-aeration device comprises a re-aeration pipe and a windmill. The re-aeration pipe has a tubular structure with openings at both ends; one end inserts into the wetland substrate, and the other end connects with the windmill for receiving and accelerating air flow. The re-aeration pipe may also contain several telescoped or parallel arranged pipes with openings at both ends as well as with different pipe diameters and lengths, which connect with the windmill to form the re-aeration device. The present disclosure also provides a method of re-aeration for constructed wetlands by using the above-mentioned device. The re-aeration device provided herein has features of being simple in structure, environment friendly, and low-cost.
Type:
Application
Filed:
January 27, 2016
Publication date:
September 29, 2016
Applicant:
Research Institute of Forestry New Technology, Chinese Academy of Forestry
Abstract: The present invention relates to a nanosecond pulse laser device. The nanosecond pulse laser device of the present invention comprises: a light source which outputs a nanosecond pulse laser beam; a lens which focuses the laser beam; a Raman shift optical fiber which generates pulse lasers corresponding to a plurality of wavelengths through stimulated Raman scattering of the focused laser beam; a wavelength divider which divides, from among the pulse lasers, the pulse lasers of a predetermined wavelength; an optical switch which selects the pulse lasers outputted from the wavelength divider to mutually alternate the wavelengths in response to a switch control signal which is applied from the outside; and a wavelength combiner which combines and outputs the pulse lasers whose wavelengths are alternatively outputted from the switch.
Type:
Application
Filed:
July 8, 2014
Publication date:
September 29, 2016
Applicants:
KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE, PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION
Abstract: Methods of heterogeneous crystallization and related systems are provided. In some embodiments, a method comprises crystallizing an agent in a suspension comprising a heteronucleant and the dissolved agent. Crystallization may occur on the surface of the heteronucleant with little or no bulk crystallization and/or secondary nucleation. In some embodiments, a crystallizer may be configured to inhibit secondary nucleation and/or bulk crystallization, for example, by reducing the formation of free crystals that may serve as nucleation surfaces while allowing for adequate mass and heat transfer. In some such embodiments, the crystallizer may be designed to flow (e.g., continuously) a suspension comprising a heteronucleant and an agent in a fluidized state. The methods and systems of the present invention may be used in a wide variety of applications, including the crystallization of pharmaceutically active agents.
Type:
Application
Filed:
February 26, 2016
Publication date:
September 29, 2016
Applicant:
Massachusetts Institute of Technology
Inventors:
Bernhardt Levy Trout, Allan Stuart Myerson, Siva Rama Krishna Perala, Christopher James Testa, Keith Dale Jensen
Abstract: Possible outcomes can be determined by combining simulation methods on a pool of input variables. Certain members of the pool are identified as members of a first set of variables (e.g., priority set), and certain other members of the pool of input variables are identified as members of a second set of variables (e.g., non-priority set). A first set of possible values for the first set of variables can be generated by applying a first simulation method. A second set of possible values for the second set of variables can be generated by applying a second simulation method that differs from the first simulation method in various ways, such as accuracy, completion time, and computational expense. A copula data structure can be used to maintain correlations between the variables of the pool of input variables when generating a hybrid set of simulated values based on the first and second simulation.
Type:
Application
Filed:
February 26, 2016
Publication date:
September 29, 2016
Applicant:
SAS Institute Inc.
Inventors:
Zhiping Yang, Donald James Erdman, Stacey Michelle Christian, Wei Chen
Abstract: A heat exchanger for a steam generator according to one embodiment of the present invention comprises a plate and channels formed on the plate by an photo-chemical etching method, wherein the channels comprise: a primary heat transmission section formed in a manner of having a bent or curved flow path so as to be extended longer than the length at which one side and the other side are connected in a straight line; and a flow path resistance section, formed having a smaller width than the width of the channels formed on the primary heat transmission section and being connected to the one side of the primary transmission section in a manner of having a bent or curved flow path so as to be extended longer than the length at which an inlet and an outlet are connected in a straight line.
Abstract: The present invention features compositions and methods for identifying a subject having a B cell neoplasia or related condition responsive to treatment with lenalidomide and lenalidoinide-related compounds.
Type:
Application
Filed:
November 7, 2014
Publication date:
September 29, 2016
Applicants:
THE BROAD INSTITUTE, INC., THE BRIGHAM & WOMEN'S HOSPITAL, INC.
Inventors:
BENJAMIN LEVINE EBERT, STEVEN A. CARR, JAN KRÖNKE, NAMRATA D. UDESHI, EMMA FINK
Abstract: This invention provides a vaccinia virus that grows specifically in a cancer cell and damages such cancer cell and the use of such virus for treatment of cancer. Such mitogen-activated protein kinase-dependent vaccinia virus strain lacks functions of vaccinia virus growth factor (VGF) and O1L, it does not grow in normal cells but grows specifically in cancer cells, and it has oncolytic properties that specifically damage cancer cells.
Type:
Application
Filed:
November 20, 2014
Publication date:
September 29, 2016
Applicants:
National University Corporation Tottori University, The Chemo-Sero-Therapeutic Research Institute
Abstract: Provided is a DC current breaker having a high-speed breaking function appropriate to a voltage-type converter and a DC current breaking method. In addition, provided is a DC current breaker and a DC current breaking method capable of reducing cost of the breaker and securing economical competiveness by using a relatively simple configuration.
Type:
Application
Filed:
September 5, 2014
Publication date:
September 29, 2016
Applicant:
KOREA ELECTROTECHNOLOGY RESEARCH INSTITUTE
Inventors:
Woo Young LEE, Sang Hun PARK, Ki Dong SONG, Hyun Jae JANG, Jin Kyo CHONG
Abstract: A method for fabricating assemblies includes providing first and second components that include ceramic, metal, or composite; positioning a multiphase joining interlayer between the first and second components, wherein the joining interlayer includes a first phase that melts at a first temperature and a second phase interspersed throughout the first phase, and wherein the second phase melts at a second temperature that is lower than the melting temperature of the first phase; and heating the joining interlayer to a temperature in the range of 725° C. to 1450° C. for a predetermined period of time to soften the first phase and melt the second phase, wherein the first phase remains in a solid or a semi-solid state, and wherein the second phase segregates to the boundaries of the first phase and transforms the joining interlayer into a substantially porosity-free adherent material that joins the first component to the second component.
Type:
Application
Filed:
June 8, 2016
Publication date:
September 29, 2016
Applicant:
EDISON WELDING INSTITUTE, INC.
Inventors:
Edward D. HERDERICK, Kirk E. COOPER, Nathan D. AMES
Abstract: Provided is a magnetic resonance imaging (MRI) apparatus for generating an MR image based on a steady state free procession (SSFP) sequence. The MRI apparatus includes: a radio frequency (RF) controller configured to apply to an object a first RF pulse corresponding to a first slice and a second RF pulse corresponding to a second slice; a gradient magnetic field controller configured to control respective gradient magnetic fields in a first direction corresponding to the first and second RF pulses, from among spatial encoding gradients, to have opposite polarities with respect to each other; a data acquisition unit configured to acquire first and second MR signals corresponding to the first and second slices; and an image processor configured to generate first and second MR images corresponding to the first and second slices, respectively, based on the acquired first and second MR signals.
Type:
Application
Filed:
March 24, 2016
Publication date:
September 29, 2016
Applicants:
KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
Abstract: A method for detecting onset of oscillatory instability in a device is described. The method includes obtaining a symbolic time series of a time series signal corresponding to a dynamic state variable of the device. The method further includes detecting the onset of oscillatory instability in the device based on the symbolic time series.
Abstract: In a medical phantom using a plurality of unit blocks related to an example of the present invention, the plurality of unit blocks includes a first unit block of a hexahedron shape with an empty interior; and a second unit block of a hexahedron shape with an empty interior, having a plurality of ridges formed on a top and a plurality of furrows formed on a bottom to be combined with the plurality of ridges, and the medical phantom is determined according to a combination form of the first unit block and the second unit block.
Type:
Application
Filed:
September 10, 2013
Publication date:
September 29, 2016
Applicant:
Korea Research Institute of Standards and Science
Abstract: Canine subjects are screened for vector-borne diseases using Thymidine kinase (TK1) activity level alone or in conjunction with c-reactive protein (CRP) as biomarkers in the blood serum. While the canine subject may or may not display health symptoms indicative specifically of a vector-borne disease, the activity level of TK1 or in conjunction with the concentration of CRP are combined in a novel method that provides a practitioner the means of determining whether the subjects has a high probability of being affected by a vector-borne disease.
Abstract: A system and process are disclosed for electrochemically upgrading bio-oils and bio-crudes that enhance yields of selected reduction products for subsequent production of bio-based fuels.
Type:
Application
Filed:
March 23, 2016
Publication date:
September 29, 2016
Applicants:
BATTELLE MEMORIAL INSTITUTE, BATTELLE ENERGY ALLIANCE, LLC
Inventors:
Michael A. Lilga, Asanga B. Padmaperuma, Tedd E. Lister, Eric J. Dufek, Lucia M. Petkovic, Luis A. Diaz-Aldana
Abstract: A device for handling oil pipes and a method for workover includes a base, which includes an oil pipe bearing area extending in a longitudinal direction, the oil pipe bearing area being provided therein with at least one positioning member arranged in a transverse direction perpendicular to the longitudinal direction of the base, for positioning an oil pipe; and a movable oil pipe grasping assembly, which is located above the base and configured to grasp the oil pipe and place the oil pipe in the oil pipe bearing area, or grasp the oil pipe from the oil pipe bearing area and place the oil pipe in an area outside the oil pipe bearing area. The device for handling oil pipes provided by the present disclosure is able to achieve automatic handling of oil pipes, thereby decreasing labor intensity of operators, and improving working efficiency and safety factors of the work.
Type:
Application
Filed:
March 24, 2016
Publication date:
September 29, 2016
Applicants:
China Petroleum & Chemical Corporation, Research Institute of Petroleum Engineering, Shengli Oil Field, SINOPEC
Inventors:
Zenglin WANG, Guangqi GAO, Lei ZHANG, Zeng FU, Huihui SONG, Qingsheng JIA, Bin WEI, Qingong ZHI, Qianwen TANG, Qiuhan SU, Fangyuan ZHANG, Liwei HAO
Abstract: The invention discloses a use of paracetamol and a pharmaceutical preparation containing the same in preparation of anti-HPV drugs. The novel anti-HPV pharmaceutical preparation of the invention has a significant anti-HPV effect and low toxicity, and can be used for preventing and treating clinical symptoms caused by HPV infection, especially common warts, plane warts, plantar wart, vulvar cancer, penile neoplasms, anal carcinoma, prostate cancer, bladder cancer, cervical cancer, rectal cancer, oral cancer, tonsil cancer and the like.
Type:
Application
Filed:
July 14, 2014
Publication date:
September 29, 2016
Applicant:
INSTITUTE OF BIOMEDICAL ENGINEERING CHINESE
Inventors:
Tianjun LIU, Shuai MENG, Lihui ZHAO, Ge HONG
Abstract: The present disclosure relates to a method of producing a multilayer hexagonal boron nitride (h-BN) thick film on a substrate, and more particularly, to a method of forming a multilayer h-BN thick film on a substrate including (a) a substrate heating step of heating a first substrate, (b) a h-BN precursor supply step of supplying h-BN precursors to the heated first substrate, (c) a precursor dissolving step of dissolving the supplied h-BN precursors in the first substrate, and (d) a substrate cooling step of cooling the first substrate containing the dissolved h-BN precursors therein, and a laminate including a multilayer h-BN thick film prepared by the preparation method and a substrate which forms a stack structure with the h-BN thick film
Type:
Application
Filed:
February 26, 2016
Publication date:
September 29, 2016
Applicant:
Korea Institute of Science and Technology (KIST)
Abstract: An RFID reader, RFID tag, and method thereof for performing a write check of tag data. According to an exemplary embodiment, the RFID reader may include: a transmitter to transmit a write check command to an RFID tag; a receiver to receive a response including a check value of data, which needs a write check, from an RFID tag that has received the write check command; and a controller to perform information transmission and reception processes, and check data written on the RFID tag by using the received response.
Type:
Application
Filed:
March 25, 2016
Publication date:
September 29, 2016
Applicant:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Kyu Won HAN, Chan Won PARK, Dong Beom SHIN, Sang Hyun MO